Aguirre-Arteta, Ana Maria: REGULATION OF DNA METHYLATION DURING DEVELOPMENT: ALTERNATIVE ISOFORMS OF DNA METHYLTRANSFERASE

B PERSONAL RECORD

Name: Ana Maria Aguirre-Arteta

Date of birth: 2.01.68, Bilbao (Spain)

Marital status: Single

Nationality: Spanish

EDUCATION

8/1986-6/1991 Bachelor in Technical Biology .

Basque University. Faculty of Biological Sciences.

Lejona. Spain .


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2/1993-2/1996 Master in Medical Sciences.

University of Natal. Durban. South Africa.

Title: The relative contribution of the p53 tumor suppressor gene and the human papilloma virus to cancer of the cervix in black women.

Supervisor: Dr RJ Pegoraro. Department of Chemical Pathology. University of Natal. Durban. South Africa.

2/1996-3/2000 PhD student.

Title: Regulation of DNA methylation during development: Alternative isoforms of DNA methyltransferase.

Max Delbrück Center for Molecular Medicine. Franz Volhard Clinic.

Humboldt University . Berlin. Germany.

Supervisors: Drs MC Cardoso and H Leonhardt.

RESEARCH EXPERIENCE

7/ -8/1991 Food and water analysis. Microbiology Department.

Bilbao Public Health. Spain.

5/-9/1992 Analysis of hazardous chemical compounds.

Technical Biology Department. Dublin City University. Glasnevin. Dublin. Ireland.

11/-12/1993 Training in chromatography techniques.

Langet Laboratories. Durban. South Africa.

MEETINGS AND PAPERS PRESENTED

Congresses: * Federation of South African Societies of Pathology 34th Annual Congress, 3-6 July 1994.

University of Cape Town. South Africa.

* Faculty Research Day, 7-Sep. 1994.

Faculty of Medicine. University of Natal. Durban. South Africa.

Title: Loss of heterozygosity of the p53 tumor suppressor gene is not common in cervical cancer in Black South Africans.

Congresses: * Federation of South African Societies of Pathology, 35th Annual Congress, 2-5 July 1995.

Bloemfontein. South Africa.

* Faculty Research Day, 6- Sep. 1995.

Faculty of Medicine. University of Natal. Durban. South Africa.

Title: Confirmation of the low frequency of p53 aberrations in tumors of the cervix.


III

AWARDS AND HONORS

During my research carried out in Dublin I was awarded the COMETT fellowship.

My Masters studies in South Africa were supported with a Postgraduate Scholarship from the Faculty of Medicine Kennedy Potts Cancer Research Endowment Fund and the Cancer Association of South Africa.

During my PhD studies in Berlin, I was awarded a prize for poster presentation at the 5th Graduate MDC Students‘ Symposium.

PUBLICATIONS

Chetty R., Bramdev A., Aguirre-Arteta A., Pegoraro R.J., Sataar N. Relation between retinoblastoma and p53 proteins in human papilloma viruses 16/18 positive and negative cancers of the uterine cervix. Journal of Clinical Pathology, 1997: 50 (5): 413-416.

Krämer J., Aguirre-Arteta A.M., Corinna T., Gross C.M., Dietz R., Cardoso M.C., Leonhardt H. A novel isoform of the smooth muscle cell differentiation marker smoothelin. Journal of Molecular Medicine, 1999: 77: 294-298.

*Margot J.B., *Aguirre-Arteta A.M., Di Giacco B.V., Pradham S., Roberts R.J., Cardoso M.C., Leonhardt H. Structure and Function of the Mouse DNA Methyltransferase Gene. Dnmt1 shows a tripartite structure. Journal of Molecular Biology, 2000: 297 (2): 293-300. *Shared first authorship.

Aguirre-Arteta A. M., Cardoso M. C., Leonhardt H. Expression of an alternative Dnmt1 isoform during muscle differentiation. Submitted.


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