Bartels, Anna-Maria : Durchflußzytometrische Untersuchungen zur zellulären Pharmakokinetik von freiem und liposomal verkapseltem Daunorubicin

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Literaturverzeichnis

1. Reinhardt G., Seidel H.-J., Sonntag H.-G. et al .: "Ökologisches Stoffgebiet" . 1. Auflage Hippokrates , Stuttgart 1991

2. Robert Koch Institut ", Arbeitsgemeinschaft Bevölkerungsbezogener Krebsregister in Deutschland" , 2000

3. Forth W., Henschler D., Rummel W. et al .: "Pharmakologie und Toxikologie" . 6. Auflage Bibliographisches Institut & F.A. Brockhaus AG, Mannheim 1993

4. Weinshilboum R.M.: "The therapeutic revolution" . Clin Pharmacol Ther 1987 ; 42: 481

5. Karow T., Lang R.: "Pharmakologie und Toxikologie" . 7. Auflage Druckerei Hansen 1999, Pulheim

6. Storm G., Roerdink F.H., Steerenberg P.A. et al ".: Influence of lipid composition on the antitumour activity exerted by doxorubicin-containing liposomes in a rat solid tumour model." Cancer Res 1987 ; 47 : 3366

7. Storm G.,van Bloois L., Steerenberg P.A., et al ".: Liposome encapsulation of doxorubicin: pharmaceutical and therapeutic aspects" . J. Contrl. Release 1989 ; 9 : 215

8. Andreoni A., Colasanti A., Kisslinger A. et al ".: Fluorometric determination of the kinetics of anthracyclines uptake by cells" . J Biochem Biophys Meth 1993 ; 28 : 53- 68

9. Grochow L.B., Ames M.M .: A clinican´s guide to chemotherapy, pharmakokinetics and pharmacodynamic . William and Wilkins, Baltimore, Philadelphia, London 1998.

10. Di Marco A., Gaetani M., Dorigotti L. et al .: "Studi sperimentali sull´attivita´antineoplastica del nuovo antibiotico daunomicina." Tumori 1963 ; 49: 203-217

11. Dubost M., Ganter P., Maral R. et al .: Un nouvel antibiotique à propriétés cytostatique: la rubidomycine. C.R. Academie des Sciences 1963; 257: 1813-1815

12. Robert J.: Anthracyclines , in Grochow L.B. (Hrsg): "A clinican´s guide to chemotherapy, pharmacokinetics and pharmacodynamic" 1998 , S.93-131

13. Dorr R.T., Von Hoff D.D.: Cancer Chemotherapy Handbook . 2nd ed. Appleton & Lange , Norwalk 1994


72

14. Seeber S., Schütte J.: Therapiekonzepte Onkologie . 1. Auflage Springer Verlag , Berlin Heidelberg 1993

15. Doroshow J.H .: Anthracyclines and Anthracenediones ", Chapter 17. Cancer Chemotherapy and Biotherapy" , 2nd ed., edited by Bruce A., Chabner and Dan L. Longo. Lippincott-Raven Publishers , Philadelphia 1996

16. Sweatman T.W., Israel M .: Anthracyclines ", Chapter 5. Cancer Therapeutics, Experimental and Clinical Agents," edited by B. A. Teicher 1997

17. Zeller W.J ".: Anthrazykline: Onkologie. Grundlagen, Diagnostik, Therapie und Entwick- lung" , Zur Hausen-Onkologie . Ecomed 2000; S. 1-20

18. Nagasawa K., Natazuka T., Nomiyama M. et al.: "Transport Mechanism of Anthracycline Derivates in Human Leukemia Cell line: Uptake and Efflux of Daunorubicin and Doxorubicin in HL60 and its Resistant Cells and Comparison with those of Pirarubicin" . Biol. Pharm. Bull . 1996; 19 :100-105

19. Forssen E.A., Malé-Brune R., Adler-Moore J.P. et al .: "Fluorescence Imaging Studies for the Disposition of Daunorubicin Liposomes (DaunoXome) within Tumor Tissue" . Cancer Research 1996; 56 : 2059-2065

20. Morjani H., Millot J.-M., Belhoussine R. et al.: "Anthracycline subcellular distribution in human leukemic cells by microspectrofluorometry: factors contributing to drug-induced cell death and reversal of multidrug resistance" . Leukemia 1997; 11: 1170-1179

21. Powis G ".: Anthracycline metabolism and free radical formation" , in: Powis G., Prough R. A. (Hrsg): Metabolism and action of anti-cancer drugs . Taylor & Francis , London 1987 ; S. 211- 260

22. Alberts D.S., Bachur N.R., Hotzman J.L ".:The pharmacokinetics of daunomycin in man" . Clin Pharmacol Ther 1971 ; 12 : 96-104

23. Huffman D.H., Bachur N.R. : "Daunorubicin metabolism in acute non-lymphozytic leukemia" . Blood 1972 b; 39 : 637-643

24. Rahmann A., Goodman A., Foo W ".: Clinical pharmacology of daunorubicin in phase I "

"patients with solid tumors: development of an analytic methodology for daunorubicin and its metabolits" . Semin Oncol 1984 ; 11 : 36-44

25. Possinger K., Hartenstein R., Ehrhart H ".: In-vitro Resistenztestung von Tumoren gegenüber Zytostatika" . Onkologie 1980 ; 6: 291-300


73

26. Boven E., de Jong J., Kuiper C.M. et al ".: Relationship Between the Tumour Tissue Pharmacokinetics and the Antiproliferativ Effects of Anthracyclines and their Metabolites" . European Journal of Cancer (Vol. 32A ) 1996 ; 8 : 1382-1387

27. Possinger K., Wagner H., Worst P. et al.: "Oral Administration of Idarubicin as First Line Cytostatic Therapy in Patients with Metastasized Breast Cancer and Favourable Prognosis" . Onkologie 1991 ; 14: 31-34

28. Cusack B.J., Young S.P., Vestal R. et al ".: Age-related pharmacokinetics of daunorubicin and daunorubicinol following intravenous bolus daunorubicin administration in the rat." Cancer Chemother Pharmacol 1997 ; 39 : 505-512

29. Nielsen D., Maare C., Skovsgaard T ".: Cellular Resistance to Anthracyclines. Gen. Pharmac. (Vol. 27) 1996; 2: 251-255Cassidy J.: Pharmacokinetics, Targeting and Delivery Systems in Anthracycline-resistant Cancers" . European Journal of Cancer (Vol. 31 A) 1995 ; 7 : 18-20

30. Bogush T.,Smirnova G., Shubina I. et al.: "Direct evaluation of intracellular accumulation of free and polymer-bound anthracyclines" . Cancer Chemother Pharmacol 1995 ; 35 : 501-505

31. Bangham A.D., Standish M.M., Watkins J.C.: "Diffusion of univalent ions across the lamellae of swollen phospholipids." J. Mol. Biol . 1965 ; 13 : 238-252

32. Sessa G., Weissmann G ".: Phospholipid spherules (liposomes) as a model for biological membranes" . J. Lipid. Res . 1968 ; 9 : 310-318

33. Ranson M., Howell A., Cheeseman S ".: Liposomal drug delivery" . Cancer Treatment Reviews 1996; 22: 365-379

34. Storm G., Crommelin D.J.A ".: Colloidal Systems for Tumor Targeting" . Hybridoma (Vol. 16 ) 1997 ; 1 : 119-125

35. Allen T.M., Hansen C.B., Lopes D.E. et al ".: Pharmacokinetics of long-circulating liposomes" . Advanced Drug Delivery Reviews 1995 ; 16 : 267-284

36. Oku N., Namba Y.: "Long-Circulating Liposomes" . Critical Reviews in Therapeutic Drug Carrier Systems 1994; 11 (4 ): 231-270

37. Forssen E.A., Ross M. E.: "Daunoxome Treatment of Solid Tumors: Preclinical and Clinical Investigations" . Journal of Liposome Research 1994 ; 4 : 481-512

38. Sharma A., Sharma U.S.: "Liposomes in drug delivery: progress and limitations" . International Journal of Pharmaceutics 1997 ; 154 : 123-140

39. Massing U.: "Cancer therapy with liposomal formulations of anticancer drugs" . Int. J. Clin. Pharmacol. Ther. 1997 ; 35 : 87-90


74

NeXstar Pharmaceuticals: "DaunoXome, liposomal daunorubicin" . Braunschweig 1996

40. Sargent J.M., Elgie A.W., Williamson C.J. et al ".: In Vitro Sensitivity to the Liposomal Preparation, DaunoXome in CLL" . Anticancer Research 1999 ; 19 : 3253-3258

41. Richardson D.S., Kelsey S.M., Johnson S.A.: "Early evaluation of liposomal daunorubicin (DaunoXome) in the treatment of relapsed and refractory lymphoma. Investigational" New Drugs 1997 ; 15: 247-253

42. Forssen E.A., Coulter D.M, Proffitt R.T.: "Selective In Vivo Localization of Daunorubicin Small Unilamellar Vesicals in Solid Tumors" . Cancer Research 1992 ; 52 : 3255-3261

43. Gill P.S., Espina B.M., Muggia F. et al .: "Phase I/II Clinical and Pharmacokinetic Evaluation of Liposomal Daunorubicin." Journal of Clinical Oncology (Vol.13 ) 1995 ; 4 : 996-1003

44. Yeo W., Chan K.K., Mukwaya G. et al ".: Phase II studies with DaunoXome in patients with nonresectable hepatocellular carcinoma: clinical and pharmacokinetic outcomes." Cancer Chemother Pharmacol 1999 ; 44: 124-130

45. Fumagalli L., Zucchetti M., Parisi I. et al ".: The pharmacokinetics of liposomal encapsulated daunorubicin are not modified by HAART in patients with HIV-associated Kaposi´s sarcoma" . Cancer Chemother Pharmacol 2000 ; 45 : 495-501

46. Ermacora A., Michieli M., Pea F. et al ".: Liposome encapsulated daunorubicin (daunoxome) for acute leukemia" . Haematologica 2000; Vol.85 (3 )

47. Pratt G., Wiles M.E., Rawstron A.C. et al.: "Liposomal Daunorubicin: In Vitro and In Vivo Efficacy In Multiple Myeloma" . Hematological Oncology 1998 ; 16 : 47-55

Research Reports : "Daunoxome Data Presented at International Cancer Meeting. " Oncology (Vol. 10 ) 1996 ; 6: 830

48. Rahman A., Husai S.R., Siddiqui J. et al ".: Liposome -Mediated Modulation of Multidrug Resistance in Human HL-60 Leukemia Cells" . J Natl Cancer Inst 1992 ; 84 : 1909-1915

49. Van Engeland M., Nieland L.J.W., Ramaekers F.C.S ".: Annexin V-Affinity Assay: A Review on an Apoptosis Detection System Based on Phosphatidylserine Exposure" . Cytometry 1998 ; 31 : 1-9

50. Thomas C .: Histopathologie . 12.Auflage, Schattauer , Stuttgart 1998.

51. Bogensberger S., Boss N., Büttner M. et al .: Roche Lexikon Medizin 4.Auflage. Urban & Schwarzenberg , München 1999


75

52. Vial J-P., Belloc F., Dumain P. et al ".: Study of the apoptosis induced in vitro by antitumoral drugs on leukemic cells" . Leukemia Research (Vol. 21) 1997 ; 2 : 163-172

53. Gieseler F., Biersack H., Brieden T. et al .: "Cytotoxicity of anthracyclins: correlation with cellular uptake, intracellular distribution and DNA binding" . Ann Hematol 1994 ; 69 : 13-17

54. Gieseler F., Nüßler V., Brieden T., et al ".: Intracellular pharmacokinetics of anthracyclines in human leukemia calls: correlation of DNA-binding with apoptotic cell death" . Int J Clin Pharmacol Ther (Vol. 1 ) 1997 ; 36: 25-28

55. Negri C., Bernardi R., Donzelli M. et al ".: Induction of apoptotic cell death by DNA topoisomerase II inhibitor." Biochimi 1995; 77 : 893-899

56. Solary E., Bertrand R., Pommier Y ".: Apoptosis induced by DNA topoisomerase I and II inhibitors in human leukemic HL 60 cells" . Leuk Lymphoma 1994 ; 15 : 21-32

57. Darzynkiewicz Z., Juan G., Li X. et al.: "Cytometry in Cell Necrobiology: Analysis of Apoptosis and Accidental Cell Death (Necrosis)." Cytometry 1997 ; 27 : 1-20

58. Garland J.M., Halestrap A .: "Energy Metabolism during Apoptosis" . The Journal of Biological Chemistry (Vol. 272 ) 1997 ; 8 : 4680-4688

59. Shidoji Y., Nakamura N., Moriwaki H. et al.: "Rapid Loss in Mitochondrial Membrane Potential during Geranylgeranoic Acid-Induced Apoptosis" . Biochemical and Biophysical Research Communications 1997 ; 230 : 58-63

60. Hess K.L., Babcock G.F., Askew D.S. et al ".: A Novel Cytometric Method for Quantifying Phagocytosis of Apoptotic Cells" . Cytometry 1997 ; 27 : 145-152

61. Hara S., Dorota H., Bruno S. et al ".: Effect of Protease Inhibitors on Early Events of Apoptosis." Experimental Cell research 1996 ; 223 : 372-384

62. Gorman A.M., Samali A., McGowan A.J. et al .: "Use of Flow Cytometry Techniques in Studying Mechanisms of Apoptosis in Leukemic Cells" . Cytometry 1997 ; 29: 97-105

63. Wadia J.S., Chalmers-Redman R.M.E., Ju W.J.H. et al ".: Mitochondrial Membrane Potential and Nuclear Changes in Apoptosis Caused by Serum and Nerve Growth Factor Withdrawel: Time Course and Modification by (-) -Deprenyl" . The Journal of Neuroscience (Vol. 3 ) 1998 ; 18 : 932-947

64. Waring P., Beaver J.: "Cyclosporin A Rescue Thymocytes from Apoptosis Induced by Very Low Concentrations of Thapsigargin: Effects on Mitochondrial Function" . Experimental Cell Reseach 1996 ; 227: 264-276


76

65. Isaacs J.T.: "Role of programmed cell death in carcinogenesis" . Envir Health Perspectives (Suppl 5 ) 1993 ; 101: 27-34

66. Ferlini C., Di Cesare S., Rainaldi G. et al.: "Flow Cytometric Analysis of the Early Phases of Apoptosis by Cellular and Nuclear Techniques" . Cytometry 1996 ; 24 : 106-115

67. Foley G.E., Lazarus, Farber S. et al.: "Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia" . Cancer 1965; 18 : 522-529

68. Tarasiuk J., Foucrier J., Garnier-Suillerot A ".: Cell cycle dependent uptake and release anthracycline by drug-resistent and drug-sensitive human leukaemic K62 cells" . Biochem.Pharmacol . 1993 ; 45 (9 ): 1801-1808

69. Mc Gown A.T., Ward T.H., Fox B.W ".: Comparative Studies on the Uptake of Daunorubicin in Sensitive and Resistant P388 Cell Lines by Flow Cytometry and Biochemical Extraction Procedures" . Cancer Chemother Pharmacol 1983 ; 11 : 113-116

70. Flath B., Possinger K ".: Wert der Durchflußzytometrie bei der Diagnostik und Verlaufsbeurteilung von Leukämien und Lymphomen" . Krebs 1997 ; 16 (1 ): 16-21

71. Raffael A., Nebe C.Th., Valet G.: "Grundlagen der Durchflußzytometrie" in Schmitz-Rothe (Hrsg ): Durchflußzytometrie in der klinischen Zelldiagnostik . Schattauer , Stuttgart 1994 , S. 3-48

72. Jaroszeski M.J., Radcliff G.: "Fundamentals of Flow Cytometry" . Molecular Biotechnology 1999 ; 11 : 37-53

73. Longobardi Givan A.: Flow Cytometry: First Principals . Wiley-Liss, Inc ., New York 1992

74. Inoué S.: "Foundations of Confocal Scanned Imaging in Light Microscopy" in Pawley J.B.(Hrsg): Handbook of Biological Confocal Microscopy . Plenum Press , New York 1990 , S. 1-14

75. Sheppard C.J.R.: "Confocal Microscopy: Basic Principals and System Performance" in Cheng P.C., Lin T.H., Wu W.L. et al. (Hrsg): Multidimensional Microscopy . Springer, New York 1994 , S. 1-31

76. Gratton E., Van De Ven M.J. : "Laser Source for Confocal Microscopy" in Pawley J.B.(Hrsg): Handbook of Biological Confocal Microscopy . Plenum Press , New York 1990, S. 53-67


77

77. Kitagawa H ".: Theory and Principal Technologies of the Laser Scanning Confocal Microsopy " in Cheng P.C., Lin T.H., Wu W.L., et al.(Hrsg): Multidimensional Microscopy Springer , New York 1994 , 53-71

78. Stelzer E.H.K.: "The Intermediate Optical System of Laser Scanning Confocal Microscopes in" Pawley J.B.(Hrsg ): Handbook of Biological Confocal Microscopy . Plenum Press , New York 1990 ,S. 93-103

79. Wells K.S ".: Quantitative Fluorescence Imaging with Laser Scanning Confocal Microscopy" in Pawley J.B.(Hrsg): Handbook of Biological Confocal Microscopy . Plenum Press , New York 1990 ,S. 27-39

80. Nagasawa K., Takara K., Nomiyama M. et al.: "Transport Mechanisms of Anthracycline Derivates in Human Leukemia Cell lines: Uptake of Pirarubicin, Daunorubicin and Doxorubicin by K562 and Multidrug-Resistant K562/ADM Cells." Biol. Pharm. Bull . (Vol. 7 ) 1996 ; 19 : 971-976

81. Serafino A., Sinibaldi-Vallebona P., Pierimarchi P. et al ".: Induction of Apoptosis in Neoplastic Cells by Anthracycline Antitumor Drugs: Nuclear and Cytoplasmatic Triggering?." Anticancer Research 1999 ; 19: 1909-1918

82. Serafino A., Sinibaldi-Vallebona P., Gaudiano G. et al .: "Cytoplasmatic localisation of anthracycline antitumor drugs conjugated with reduced glutathione: a possible correlation with multidrug resistant mechanisms" . Anticancer Res 1998 ; 18 : 1159-1166

83. Forssen E., Chan K.K., Muggia F.M. et al ".: Clinical pharmacokinetics of liposomal daunorubicin." Proc Am Assoc Cancer Res 1990 ; 31 : 181

"Research Reports: Daunoxome an “Active Agent“ in Patients with Relapsed or Refractory NHL, Say Independent Investigators" . Oncology (Vol. 10 ) 1996 ; 12 : 1856

84. Lautier D., Bailly J.-D., Demur C. et al.: "Altered Intracellular Distribution of Daunorubicin in Immature Acute Myeloid Leukemia Cells." Int. J. Cancer 1997 ; 71 : 292-299

85. Chiodini B., Bassan R., Barbui T.: "Cellular Uptake and Antiproliferative Effects of Therapeutic Concentrations of Idarubicin or Daunorubicin and their Alcohol Metabolites, with or without Cyclosporin A, in MDR1+ Human Leukemic cells." Leukemia and Lymphoma 1999 ; 33 (5-6 ): 485-497

86. Nooter K., Oostrum R., Jonker R. et al.: "Effect of cyclosporin A on daunorubicin accumulation in multidrug-resistent P388 leukemic cells measured by real-time flow cytometry. " Cancer Chemother Pharmacol 1989 ; 23 : 296-300


78

87. Durand R.E., Olive P.L ".: Flow Cytometry Studies of Intracellular Adriamycin in Single Cells in vitro. " Cancer Research 1981 ; 41 : 3489-3494

88. Maciorowski Z., Delic J., Padoy E. et al.: "Comparative Analysis of Apoptosis Measured by Hoechst and Flow Cytometry in NHL" . Cytometry 1998 ; 32 : 44-50


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