Publikationen

Artikel

Becker M., Gembardt F., Maul B., Walther T., Siems W.-E.: Neprilysin-deficient mice reveal increased and enhanced alcohol consumption under conditions exerting social defeat stress. (in Vorbereitung)

Becker M., Metges C. C., Kluge R., Walther T., Siems W.-E.: Mice deficient in the neprilysin gene develop an obese phenotype. (in Vorbereitung)

Walther T., Stepan H., Pankow K., Becker M., Schultheiss H.-P., Siems W.-E.: Biochemical analysis of neutral endopeptidase activity reveals independent catabolism of atrial and brain natriuretic peptide. Biol. Chem., Vol. 385, pp. 179-184, February 2004

Maul B., Krause W., Pankow K., Becker M., Gembardt F., Alenina N., Walther T., Bader M., Siems W.-E.: Central angiotensin II controls alcohol consumption via its AT1 receptor. FASEB J. 2005 Sep;19(11):1474-81.

Walther T., Albrecht D., Becker A., Becker M., Schubert M., Maul B., Schultheiss H.P., Grecksch G., Siems W.-E.: Janus head neutral endopeptidase (NEP) - improved learning and memory in old-aged mice that are deficient in the amyloid ß-degrading peptidase NEP. (in Vorbereitung)

Siems W.-E., Maul B., Wiesner B., Becker M., Walther T., Rothe L., Winkler A.: Effects of kinins on mammalian spermatozoa and the impact of peptidolytic enzymes. Andrologia. 2003 Feb;35(1):44-54.

Poster / Vorträge

Mainz / 45. Frühjahrstagung der DGPT 2004

Becker M., Kluge R., Metges C. C., Gembardt F., Siems W.-E., Walther T. (Berlin/ Potsdam/ Dummerstorf/ Rotterdam): NEP-deficient mice develop a late-onset obese phenotype: A model for human polyfactorial adipositas.

Sun X., Pankow K., Becker M., Papsdorf G., Krause W., Danilov S., Siems W.E., Maul B. (Berlin ): Expression and enzymatic properties of domain selective murine ACE

Pankow K., Becker M., Krause G., Diehl A., Walther T., Siems W.-E. (Berlin/Rotterdam): Sequential differences in the natriuretic peptides influence their catabolism by neutral endopeptidase (EC 3.4.24.11).

Walther T., Albrecht D., Becker A., Beyermann M., Pankow K., Gembardt F., Becker M., Maul B., Grecksch G., Siems W.-E. (Berlin/Magdeburg/Rotterdam): Janus head neutral endopeptidase (NEP) - improved learning and memory in old-aged mice that are deficient in the amyloid β-degrading peptidase NEP. (Vortrag)

Potsdam / 40. Wissenschaftlicher Kongress der DGE 2003

Siems W.-E., Becker M., Maul B., Walther T.: Neutrale Endopeptidase-defiziente Mäuse entwickeln eine alters- und futterabhängige Fettleibigkeit. (Vortrag)

Mainz / 44. Frühjahrstagung der DGPT 2003

Becker M., Siems W.-E., Könnecke I., Maul B., Walther T. (Berlin): Obese phenotype in NEP knockout mice: Correlation with age and diet and possible molecular mechanism.

Pankow K., Becker M., Diehl A., Krause W., Maul B., Walther T., Siems W.-E. (Berlin): Importance of neutral endopeptidase (NEP) on the catabolism of natriuretic peptides – in-vitro experiments with NEP-deficient mice.

Mainz / 43. Frühjahrstagung der DGPT 2002

Becker M., Maul B., Krause W., Walther T., Saria A., Siems W.-E.: Neutral endopeptidase (NEP) activity modifies voluntary alcohol consumption in mice.

Berlin, Sept. 2001 / Tagung der Deutschen Ges. für Andrologie / Poster:

Müller C., Alejandre-Lafont E., Becker M., Siems W-E., Schill W-B., Köhn F-M: The enzymatic degradation of angiotensin I (A I) in human semen.