<?xml version="1.0" encoding="ISO-8859-1"?><cms:container xmlns:cms="http://edoc.hu-berlin.de/diml/module/cms"><cms:document><cms:meta><cms:entry id="front" part="front" ref="front" type="front"/><cms:entry type="title">Aus der Klinik für Allgemein-, Visceral-, Gefäß- und Thoraxchirurgie der Medizinischen Fakultät der Charité &#8211; Universitätsmedizin Berlin </cms:entry><cms:entry type="title">Regulation der Stabilität der proangiogenen Transkriptionsfaktoren c-Jun, Id1 und Id3 durch das COP9-Signalosom</cms:entry><cms:entry type="author">Matthias Berse</cms:entry><cms:entry id="chapter1" part="chapter1" ref="chapter1" type="chapter">1.</cms:entry><cms:entry id="N10091" part="chapter1" ref="N10091" type="citenumber">1</cms:entry><cms:entry id="N10098" part="chapter1" ref="N10098" type="section">1.1.</cms:entry><cms:entry id="N100A2" part="chapter1" ref="N100A2" type="citenumber">2</cms:entry><cms:entry id="N100AB" part="chapter1" ref="N100AB" type="mm">313#243</cms:entry><cms:entry id="N100C8" part="chapter1" ref="N100C8" type="citenumber">3</cms:entry><cms:entry id="I_Ref101617014" part="chapter1" ref="I_Ref101617014" type="link"/><cms:entry id="N100DC" part="chapter1" ref="N100DC" type="section">1.2.</cms:entry><cms:entry id="N100E1" part="chapter1" ref="N100E1" type="subsection">1.2.1.</cms:entry><cms:entry id="N100EB" part="chapter1" ref="N100EB" type="citenumber">4</cms:entry><cms:entry id="N10115" part="chapter1" ref="N10115" type="citenumber">5</cms:entry><cms:entry id="N1011C" part="chapter1" ref="N1011C" type="subsection">1.2.2.</cms:entry><cms:entry id="N10129" part="chapter1" ref="N10129" type="citenumber">6</cms:entry><cms:entry id="I_Ref101617281" part="chapter1" ref="I_Ref101617281" type="link"/><cms:entry id="I_Ref101617354" part="chapter1" ref="I_Ref101617354" type="link"/><cms:entry id="I_Ref101617713" part="chapter1" ref="I_Ref101617713" type="link"/><cms:entry id="N10141" part="chapter1" ref="N10141" type="section">1.3.</cms:entry><cms:entry id="N10146" part="chapter1" ref="N10146" type="subsection">1.3.1.</cms:entry><cms:entry id="N1014F" part="chapter1" ref="N1014F" type="subsection">1.3.2.</cms:entry><cms:entry id="N1015F" part="chapter1" ref="N1015F" type="citenumber">7</cms:entry><cms:entry id="N10168" part="chapter1" ref="N10168" type="mm">352#405</cms:entry><cms:entry id="N10188" part="chapter1" ref="N10188" type="citenumber">8</cms:entry><cms:entry id="N101A2" part="chapter1" ref="N101A2" type="subsection">1.3.3.</cms:entry><cms:entry id="N101AC" part="chapter1" ref="N101AC" type="citenumber">9</cms:entry><cms:entry id="N101B1" part="chapter1" ref="N101B1" type="subsection">1.3.4.</cms:entry><cms:entry id="N101C2" part="chapter1" ref="N101C2" type="section">1.4.</cms:entry><cms:entry id="N101C7" part="chapter1" ref="N101C7" type="subsection">1.4.1.</cms:entry><cms:entry id="N101CE" part="chapter1" ref="N101CE" type="citenumber">10</cms:entry><cms:entry id="N101D3" part="chapter1" ref="N101D3" type="subsection">1.4.2.</cms:entry><cms:entry id="N101F9" part="chapter1" ref="N101F9" type="citenumber">11</cms:entry><cms:entry id="N1020E" part="chapter1" ref="N1020E" type="mm">468#270</cms:entry><cms:entry id="N10228" part="chapter1" ref="N10228" type="citenumber">12</cms:entry><cms:entry id="N10230" part="chapter1" ref="N10230" type="subsection">1.4.3.</cms:entry><cms:entry id="N1026F" part="chapter1" ref="N1026F" type="subsection">1.4.4.</cms:entry><cms:entry id="N10276" part="chapter1" ref="N10276" type="citenumber">13</cms:entry><cms:entry id="I_Ref101617686" part="chapter1" ref="I_Ref101617686" type="link"/><cms:entry id="N10285" part="chapter1" ref="N10285" type="section">1.5.</cms:entry><cms:entry id="N1028D" part="chapter1" ref="N1028D" type="subsection">1.5.1.</cms:entry><cms:entry id="N10297" part="chapter1" ref="N10297" type="citenumber">14</cms:entry><cms:entry id="N102A1" part="chapter1" ref="N102A1" type="mm">370#282</cms:entry><cms:entry id="N102B4" part="chapter1" ref="N102B4" type="subsection">1.5.2.</cms:entry><cms:entry id="N102BB" part="chapter1" ref="N102BB" type="citenumber">15</cms:entry><cms:entry id="N102C1" part="chapter1" ref="N102C1" type="mm">472#239</cms:entry><cms:entry id="N102D5" part="chapter1" ref="N102D5" type="citenumber">16</cms:entry><cms:entry id="I_Ref101617651" part="chapter1" ref="I_Ref101617651" type="link"/><cms:entry id="N102E1" part="chapter1" ref="N102E1" type="section">1.6.</cms:entry><cms:entry id="N102E6" part="chapter1" ref="N102E6" type="subsection">1.6.1.</cms:entry><cms:entry id="N102F6" part="chapter1" ref="N102F6" type="mm">579#184</cms:entry><cms:entry id="N1030D" part="chapter1" ref="N1030D" type="citenumber">17</cms:entry><cms:entry id="N10316" part="chapter1" ref="N10316" type="subsection">1.6.2.</cms:entry><cms:entry id="N1031B" part="chapter1" ref="N1031B" type="block">1.6.2.1.</cms:entry><cms:entry id="I_Ref101617293" part="chapter1" ref="I_Ref101617293" type="link"/><cms:entry id="N10335" part="chapter1" ref="N10335" type="citenumber">18</cms:entry><cms:entry id="I_Ref101617408" part="chapter1" ref="I_Ref101617408" type="link"/><cms:entry id="N10343" part="chapter1" ref="N10343" type="block">1.6.2.2.</cms:entry><cms:entry id="N10355" part="chapter1" ref="N10355" type="citenumber">19</cms:entry><cms:entry id="chapter2" part="chapter2" ref="chapter2" type="chapter">2.</cms:entry><cms:entry id="N10368" part="chapter2" ref="N10368" type="helpercitenumber">19</cms:entry><cms:entry id="N1036D" part="chapter2" ref="N1036D" type="citenumber">20</cms:entry><cms:entry id="chapter3" part="chapter3" ref="chapter3" type="chapter">3.</cms:entry><cms:entry id="N1037A" part="chapter3" ref="N1037A" type="section">3.1.</cms:entry><cms:entry id="N1037F" part="chapter3" ref="N1037F" type="subsection">3.1.1.</cms:entry><cms:entry id="N10384" part="chapter3" ref="N10384" type="helpercitenumber">20</cms:entry><cms:entry id="N10386" part="chapter3" ref="N10386" type="table"/><cms:entry id="N103E0" part="chapter3" ref="N103E0" type="subsection">3.1.2.</cms:entry><cms:entry id="N103E7" part="chapter3" ref="N103E7" type="citenumber">21</cms:entry><cms:entry id="N103EA" part="chapter3" ref="N103EA" type="table"/><cms:entry id="N10434" part="chapter3" ref="N10434" type="subsection">3.1.3.</cms:entry><cms:entry id="N1043B" part="chapter3" ref="N1043B" type="table"/><cms:entry id="N104D4" part="chapter3" ref="N104D4" type="subsection">3.1.4.</cms:entry><cms:entry id="N104DB" part="chapter3" ref="N104DB" type="table"/><cms:entry id="N105D2" part="chapter3" ref="N105D2" type="subsection">3.1.5.</cms:entry><cms:entry id="N105D9" part="chapter3" ref="N105D9" type="citenumber">22</cms:entry><cms:entry id="N105DC" part="chapter3" ref="N105DC" type="table"/><cms:entry id="N10660" part="chapter3" ref="N10660" type="subsection">3.1.6.</cms:entry><cms:entry id="N10667" part="chapter3" ref="N10667" type="table"/><cms:entry id="N109BA" part="chapter3" ref="N109BA" type="subsection">3.1.7.</cms:entry><cms:entry id="N109C1" part="chapter3" ref="N109C1" type="table"/><cms:entry id="N10CFB" part="chapter3" ref="N10CFB" type="section">3.2.</cms:entry><cms:entry id="N10D00" part="chapter3" ref="N10D00" type="subsection">3.2.1.</cms:entry><cms:entry id="N10D0D" part="chapter3" ref="N10D0D" type="citenumber">23</cms:entry><cms:entry id="N10D3C" part="chapter3" ref="N10D3C" type="subsection">3.2.2.</cms:entry><cms:entry id="N10D46" part="chapter3" ref="N10D46" type="citenumber">24</cms:entry><cms:entry id="I_Ref101617786" part="chapter3" ref="I_Ref101617786" type="link"/><cms:entry id="N10D78" part="chapter3" ref="N10D78" type="subsection">3.2.3.</cms:entry><cms:entry id="N10D84" part="chapter3" ref="N10D84" type="subsection">3.2.4.</cms:entry><cms:entry id="N10D8B" part="chapter3" ref="N10D8B" type="citenumber">25</cms:entry><cms:entry id="N10D95" part="chapter3" ref="N10D95" type="subsection">3.2.5.</cms:entry><cms:entry id="N10DA0" part="chapter3" ref="N10DA0" type="subsection">3.2.6.</cms:entry><cms:entry id="N10DA7" part="chapter3" ref="N10DA7" type="citenumber">26</cms:entry><cms:entry id="I_Ref101616811" part="chapter3" ref="I_Ref101616811" type="link"/><cms:entry id="I_Ref101616831" part="chapter3" ref="I_Ref101616831" type="link"/><cms:entry id="I_Ref101616837" part="chapter3" ref="I_Ref101616837" type="link"/><cms:entry id="I_Ref101617748" part="chapter3" ref="I_Ref101617748" type="link"/><cms:entry id="N10DD3" part="chapter3" ref="N10DD3" type="subsection">3.2.7.</cms:entry><cms:entry id="N10E0A" part="chapter3" ref="N10E0A" type="citenumber">27</cms:entry><cms:entry id="I_Ref95673531" part="chapter3" ref="I_Ref95673531" type="link"/><cms:entry id="N10E1E" part="chapter3" ref="N10E1E" type="subsection">3.2.8.</cms:entry><cms:entry id="N10E31" part="chapter3" ref="N10E31" type="subsection">3.2.9.</cms:entry><cms:entry id="N10E3A" part="chapter3" ref="N10E3A" type="citenumber">28</cms:entry><cms:entry id="I_Ref95673582" part="chapter3" ref="I_Ref95673582" type="link"/><cms:entry id="N10E57" part="chapter3" ref="N10E57" type="subsection">3.2.10.</cms:entry><cms:entry id="N10E6A" part="chapter3" ref="N10E6A" type="citenumber">29</cms:entry><cms:entry id="N10E6F" part="chapter3" ref="N10E6F" type="subsection">3.2.11.</cms:entry><cms:entry id="N10EA5" part="chapter3" ref="N10EA5" type="citenumber">30</cms:entry><cms:entry id="N10EDD" part="chapter3" ref="N10EDD" type="subsection">3.2.12.</cms:entry><cms:entry id="N10EFC" part="chapter3" ref="N10EFC" type="citenumber">31</cms:entry><cms:entry id="N10F10" part="chapter3" ref="N10F10" type="subsection">3.2.13.</cms:entry><cms:entry id="N10F40" part="chapter3" ref="N10F40" type="subsection">3.2.14.</cms:entry><cms:entry id="N10F47" part="chapter3" ref="N10F47" type="citenumber">32</cms:entry><cms:entry id="N10F6A" part="chapter3" ref="N10F6A" type="subsection">3.2.15.</cms:entry><cms:entry id="N10F87" part="chapter3" ref="N10F87" type="citenumber">33</cms:entry><cms:entry id="N10F93" part="chapter3" ref="N10F93" type="subsection">3.2.16.</cms:entry><cms:entry id="N10FA0" part="chapter3" ref="N10FA0" type="citenumber">34</cms:entry><cms:entry id="N10FA8" part="chapter3" ref="N10FA8" type="subsection">3.2.17.</cms:entry><cms:entry id="N10FB3" part="chapter3" ref="N10FB3" type="subsection">3.2.18.</cms:entry><cms:entry id="N10FEB" part="chapter3" ref="N10FEB" type="citenumber">35</cms:entry><cms:entry id="N10FF3" part="chapter3" ref="N10FF3" type="subsection">3.2.19.</cms:entry><cms:entry id="N1102B" part="chapter3" ref="N1102B" type="subsection">3.2.20.</cms:entry><cms:entry id="N11032" part="chapter3" ref="N11032" type="citenumber">36</cms:entry><cms:entry id="N11047" part="chapter3" ref="N11047" type="subsection">3.2.21.</cms:entry><cms:entry id="N1105A" part="chapter3" ref="N1105A" type="citenumber">37</cms:entry><cms:entry id="I_Ref102972019" part="chapter3" ref="I_Ref102972019" type="link"/><cms:entry id="N11068" part="chapter3" ref="N11068" type="subsection">3.2.22.</cms:entry><cms:entry id="N1108B" part="chapter3" ref="N1108B" type="subsection">3.2.23.</cms:entry><cms:entry id="N11092" part="chapter3" ref="N11092" type="citenumber">38</cms:entry><cms:entry id="N110C1" part="chapter3" ref="N110C1" type="subsection">3.2.24.</cms:entry><cms:entry id="chapter4" part="chapter4" ref="chapter4" type="chapter">4.</cms:entry><cms:entry id="N110D5" part="chapter4" ref="N110D5" type="section">4.1.</cms:entry><cms:entry id="N110DA" part="chapter4" ref="N110DA" type="subsection">4.1.1.</cms:entry><cms:entry id="N110E1" part="chapter4" ref="N110E1" type="citenumber">39</cms:entry><cms:entry id="N110F6" part="chapter4" ref="N110F6" type="citenumber">40</cms:entry><cms:entry id="N110F9" part="chapter4" ref="N110F9" type="mm">585#608</cms:entry><cms:entry id="N11128" part="chapter4" ref="N11128" type="citenumber">41</cms:entry><cms:entry id="I_Ref101617062" part="chapter4" ref="I_Ref101617062" type="link"/><cms:entry id="N11133" part="chapter4" ref="N11133" type="subsection">4.1.2.</cms:entry><cms:entry id="N1114B" part="chapter4" ref="N1114B" type="citenumber">42</cms:entry><cms:entry id="N1114E" part="chapter4" ref="N1114E" type="mm">337#170</cms:entry><cms:entry id="I_Ref102678824" part="chapter4" ref="I_Ref102678824" type="link"/><cms:entry id="N11167" part="chapter4" ref="N11167" type="subsection">4.1.3.</cms:entry><cms:entry id="N1117A" part="chapter4" ref="N1117A" type="citenumber">43</cms:entry><cms:entry id="N1117D" part="chapter4" ref="N1117D" type="mm">300#532</cms:entry><cms:entry id="N1119F" part="chapter4" ref="N1119F" type="citenumber">44</cms:entry><cms:entry id="N111A8" part="chapter4" ref="N111A8" type="mm">388#603</cms:entry><cms:entry id="N111C2" part="chapter4" ref="N111C2" type="citenumber">45</cms:entry><cms:entry id="I_Ref101617065" part="chapter4" ref="I_Ref101617065" type="link"/><cms:entry id="I_Ref101617187" part="chapter4" ref="I_Ref101617187" type="link"/><cms:entry id="I_Ref101617233" part="chapter4" ref="I_Ref101617233" type="link"/><cms:entry id="I_Ref101617579" part="chapter4" ref="I_Ref101617579" type="link"/><cms:entry id="I_Ref101617583" part="chapter4" ref="I_Ref101617583" type="link"/><cms:entry id="I_Ref102908122" part="chapter4" ref="I_Ref102908122" type="link"/><cms:entry id="N111F1" part="chapter4" ref="N111F1" type="subsection">4.1.4.</cms:entry><cms:entry id="N111FA" part="chapter4" ref="N111FA" type="citenumber">46</cms:entry><cms:entry id="N1120D" part="chapter4" ref="N1120D" type="citenumber">47</cms:entry><cms:entry id="N11216" part="chapter4" ref="N11216" type="mm">383#647</cms:entry><cms:entry id="I_Ref101616906" part="chapter4" ref="I_Ref101616906" type="link"/><cms:entry id="I_Ref101616956" part="chapter4" ref="I_Ref101616956" type="link"/><cms:entry id="I_Ref101617469" part="chapter4" ref="I_Ref101617469" type="link"/><cms:entry id="I_Ref101617511" part="chapter4" ref="I_Ref101617511" type="link"/><cms:entry id="N11247" part="chapter4" ref="N11247" type="subsection">4.1.5.</cms:entry><cms:entry id="N11250" part="chapter4" ref="N11250" type="citenumber">48</cms:entry><cms:entry id="N1125A" part="chapter4" ref="N1125A" type="mm">370#286</cms:entry><cms:entry id="N11272" part="chapter4" ref="N11272" type="citenumber">49</cms:entry><cms:entry id="N1127F" part="chapter4" ref="N1127F" type="mm">570#396</cms:entry><cms:entry id="N11290" part="chapter4" ref="N11290" type="section">4.2.</cms:entry><cms:entry id="N11297" part="chapter4" ref="N11297" type="subsection">4.2.1.</cms:entry><cms:entry id="N1129E" part="chapter4" ref="N1129E" type="citenumber">50</cms:entry><cms:entry id="N112BC" part="chapter4" ref="N112BC" type="citenumber">51</cms:entry><cms:entry id="N112C2" part="chapter4" ref="N112C2" type="mm">260#528</cms:entry><cms:entry id="I_Ref95740264" part="chapter4" ref="I_Ref95740264" type="link"/><cms:entry id="N112DE" part="chapter4" ref="N112DE" type="subsection">4.2.2.</cms:entry><cms:entry id="N112E8" part="chapter4" ref="N112E8" type="citenumber">52</cms:entry><cms:entry id="N112EE" part="chapter4" ref="N112EE" type="mm">552#261</cms:entry><cms:entry id="N11308" part="chapter4" ref="N11308" type="subsection">4.2.3.</cms:entry><cms:entry id="N11326" part="chapter4" ref="N11326" type="citenumber">53</cms:entry><cms:entry id="N11329" part="chapter4" ref="N11329" type="mm">419#143</cms:entry><cms:entry id="N1133C" part="chapter4" ref="N1133C" type="subsection">4.2.4.</cms:entry><cms:entry id="N1134A" part="chapter4" ref="N1134A" type="mm">564#260</cms:entry><cms:entry id="N1135B" part="chapter4" ref="N1135B" type="citenumber">54</cms:entry><cms:entry id="N11361" part="chapter4" ref="N11361" type="mm">337#231</cms:entry><cms:entry id="N11371" part="chapter4" ref="N11371" type="subsection">4.2.5.</cms:entry><cms:entry id="N11381" part="chapter4" ref="N11381" type="citenumber">55</cms:entry><cms:entry id="N11396" part="chapter4" ref="N11396" type="citenumber">56</cms:entry><cms:entry id="N11399" part="chapter4" ref="N11399" type="mm">368#686</cms:entry><cms:entry id="N113BE" part="chapter4" ref="N113BE" type="citenumber">57</cms:entry><cms:entry id="N113CD" part="chapter4" ref="N113CD" type="mm">252#649</cms:entry><cms:entry id="N113EC" part="chapter4" ref="N113EC" type="citenumber">58</cms:entry><cms:entry id="chapter5" part="chapter5" ref="chapter5" type="chapter">5.</cms:entry><cms:entry id="N113F8" part="chapter5" ref="N113F8" type="helpercitenumber">58</cms:entry><cms:entry id="N113FB" part="chapter5" ref="N113FB" type="section">5.1.</cms:entry><cms:entry id="N11400" part="chapter5" ref="N11400" type="subsection">5.1.1.</cms:entry><cms:entry id="I_Ref101617588" part="chapter5" ref="I_Ref101617588" type="link"/><cms:entry id="N1140F" part="chapter5" ref="N1140F" type="subsection">5.1.2.</cms:entry><cms:entry id="N11418" part="chapter5" ref="N11418" type="citenumber">59</cms:entry><cms:entry id="N11429" part="chapter5" ref="N11429" type="citenumber">60</cms:entry><cms:entry id="N11440" part="chapter5" ref="N11440" type="citenumber">61</cms:entry><cms:entry id="N11458" part="chapter5" ref="N11458" type="subsection">5.1.3.</cms:entry><cms:entry id="N1145F" part="chapter5" ref="N1145F" type="citenumber">62</cms:entry><cms:entry id="N1149B" part="chapter5" ref="N1149B" type="citenumber">63</cms:entry><cms:entry id="N1149E" part="chapter5" ref="N1149E" type="mm">323#482</cms:entry><cms:entry id="I_Ref101617528" part="chapter5" ref="I_Ref101617528" type="link"/><cms:entry id="N114CC" part="chapter5" ref="N114CC" type="subsection">5.1.4.</cms:entry><cms:entry id="N114D9" part="chapter5" ref="N114D9" type="citenumber">64</cms:entry><cms:entry id="N114EB" part="chapter5" ref="N114EB" type="citenumber">65</cms:entry><cms:entry id="N114F5" part="chapter5" ref="N114F5" type="mm">341#355</cms:entry><cms:entry id="N11506" part="chapter5" ref="N11506" type="section">5.2.</cms:entry><cms:entry id="N1150B" part="chapter5" ref="N1150B" type="subsection">5.2.1.</cms:entry><cms:entry id="N11515" part="chapter5" ref="N11515" type="citenumber">66</cms:entry><cms:entry id="N1151A" part="chapter5" ref="N1151A" type="subsection">5.2.2.</cms:entry><cms:entry id="N11524" part="chapter5" ref="N11524" type="mm">296#213</cms:entry><cms:entry id="N11535" part="chapter5" ref="N11535" type="citenumber">67</cms:entry><cms:entry id="N11548" part="chapter5" ref="N11548" type="subsection">5.2.3.</cms:entry><cms:entry id="N11566" part="chapter5" ref="N11566" type="citenumber">68</cms:entry><cms:entry id="N11573" part="chapter5" ref="N11573" type="subsection">5.2.4.</cms:entry><cms:entry id="N11588" part="chapter5" ref="N11588" type="citenumber">69</cms:entry><cms:entry id="N11597" part="chapter5" ref="N11597" type="mm">571#489</cms:entry><cms:entry id="N115AE" part="chapter5" ref="N115AE" type="citenumber">70</cms:entry><cms:entry ref="N115B6" type="back"/><cms:entry id="N115B8" part="N115B8" ref="N115B8" type="abbreviation">Abkürzungsverzeichnis</cms:entry><cms:entry id="N115BF" part="N115B8" ref="N115BF" type="table"/><cms:entry id="I_Ref101616946" part="N115B8" ref="I_Ref101616946" type="link"/><cms:entry ref="N1228D" type="bibliography">Literaturverzeichnis</cms:entry><cms:entry id="N133F1" part="N133F1" ref="N133F1" type="acknowledgement">Danksagung</cms:entry><cms:entry id="N133FD" part="N133FD" ref="N133FD" type="vita">Lebenslauf</cms:entry><cms:entry id="N1340A" part="N133FD" ref="N1340A" type="table"/><cms:entry id="N134AA" part="N133FD" ref="N134AA" type="table"/><cms:entry id="N13513" part="N133FD" ref="N13513" type="table"/><cms:entry id="N1354E" part="N133FD" ref="N1354E" type="table"/><cms:entry id="N135A8" part="N135A8" ref="N135A8" type="appendix">Publikationen</cms:entry><cms:entry id="N135AA" part="N135A8" ref="N135AA" type="head"/><cms:entry id="N135AD" part="N135A8" ref="N135AD" type="p"/><cms:entry id="N135B9" part="N135A8" ref="N135B9" type="p"/><cms:entry id="N135C6" part="N135C6" ref="N135C6" type="declaration">Eidesstattliche Erklärung</cms:entry><cms:entry part="N1228D" type=":current"/><cms:entry type=":lang">de</cms:entry><cms:entry id=":contents" part="front" ref=":contents" type=":contents">Inhaltsverzeichnis</cms:entry><cms:entry type=":help"><url href="http://...">Hilfe</url></cms:entry></cms:meta><cms:content><bibliography id="N1228D">
			<head>Literaturverzeichnis</head>
			
				<citation published="yes" workType="Journal">
					<cut>Aggarwal et al., 2004</cut>: <workauthor>Aggarwal, B. B., Bhardwaj, A., Aggarwal, R. S., Seeram, N. P., Shishodia, S. &amp; Takada, Y.</workauthor>
					<articletitle>Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies</articletitle>. Anticancer Res., <number>24</number>, <pages>2783&#8211;2840</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Aggarwal et al., 2003</cut>: <workauthor>Aggarwal, B. B., Kumar, A. &amp; Bharti, A. C.</workauthor>
					<articletitle>Anticancer potential of curcumin: preclinical and clinical studies</articletitle>. Anticancer Res., <number>23</number>, <pages>363&#8211;398</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Alani et al., 1999</cut>: <workauthor>Alani, R. M., Hasskarl, J., Grace, M., Hernandez, M. C., Israel, M. A. &amp; Munger, K.</workauthor>
					<articletitle>Immortalization of primary human keratinocytes by the helix&#8211;loop&#8211;helix protein, Id-1</articletitle>. Proc. Natl. Acad. Sci. USA, <number>96</number>, <pages>9637&#8211;9641</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Almond &amp; Cohen, 2002</cut>: <workauthor>Almond, J. B. &amp; Cohen, G. M.</workauthor>
					<articletitle>The proteasome: a novel target for cancer chemotherapy</articletitle>. Leukemia, <number>16</number>, <pages>433&#8211;443</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Angel et al., 1988</cut>: <workauthor>Angel, P., Hattori, K., Smeal, T. &amp; Karin, M.</workauthor>
					<articletitle>The </articletitle>
					<articletitle>jun</articletitle>
					<articletitle> proto-oncogene is positively autoregulated by its product, Jun/AP-1</articletitle>. Cell, <number>55</number>, <pages>875&#8211;885</pages>, <pubdate>1988</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Angel et al., 1987</cut>: <workauthor>Angel, P., Imagawa, M., Chiu, R., Stein, B., Imbra, R. J., Rahmsdorf, H. J., Jonat, C., Herrlich, P. &amp; Karin, M.</workauthor>
					<articletitle>Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor</articletitle>. Cell, <number>49</number>, <pages>729&#8211;739</pages>, <pubdate>1987</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Arbiser et al., 1998</cut>: <workauthor>Arbiser, J. L., Klauber, N., Rohan, R., van Leeuwen, R., Huang, M. T., Fisher, C.,Flynn, E. &amp; Byers, H. R.</workauthor>
					<articletitle>Curcumin is an in vivo inhibitor of angiogenesis</articletitle>. Mol. Med., <number>4</number>, <pages>376&#8211;383</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Arora et al., 1971</cut>: <workauthor>Arora, R. B., Kapoor, V., Basu, N. &amp; Jain, </workauthor>
					<workauthor>A</workauthor>
					<workauthor>. P.</workauthor>
					<articletitle>Anti-inflammatory studies on Curcuma longa (turmeric)</articletitle>. Indian J. Med. Res., <number>59</number>, <pages>1289&#8211;1295</pages>, <pubdate>1971</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Battistutta et al., 2000</cut>: <workauthor>Battistutta, R., Sarno, S., De Moliner, E., Papinutto, E., Zanotti, G. &amp; Pinna, L.A.</workauthor>
					<articletitle>The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2</articletitle>. J. Biol. Chem., <number>275</number>, <pages>29618&#8211;29622</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Bech-Otschir et al., 2001</cut>: <workauthor>Bech-Otschir, D., Kraft, R., Huang, X., Henklein, P., Kapelari, B., Pollmann, C. &amp; Dubiel, W.</workauthor>
					<articletitle>COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system</articletitle>. EMBO J., <number>20</number>, <pages>1630&#8211;1639</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Bech-Otschir et al., 2002</cut>: <workauthor>Bech-Otschir, D., Seeger, M. &amp; Dubiel, W.</workauthor>
					<articletitle>The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis</articletitle>. J. Cell. Sci., <number>115</number>, <pages>467&#8211;473</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Benezra et al., 1990</cut>: <workauthor>Benezra, R., Davis, R., Lockshon, D., Turner, D. &amp; Weintraub, H.</workauthor>
					<articletitle>The protein ID &#8211; a negative regulator of helix-loop-helix DNA binding proteins</articletitle>. Cell, <number>61</number>, <pages>49&#8211;59</pages>, <pubdate>1990</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Benezra et al., 2001</cut>: <workauthor>Benezra, R., Raffi, S. &amp; Lyden, D.</workauthor>
					<articletitle>The Id proteins and angiogenesis</articletitle>. Oncogene, <number>20</number>, <pages>8334&#8211;8341</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Berse et al., 2004</cut>: <workauthor>Berse, M., Bounpheng, M., Huang, X., Christy, B., Pollmann, Ch</workauthor>
					<workauthor>. &amp;</workauthor>
					<workauthor> Dubiel, W.</workauthor>
					<articletitle>Ubiquitin-dependent degradation of Id1 and Id3 is mediated by the COP9 signalosome</articletitle>. J. Mol. Biol., <number>343</number>, <pages>361&#8211;370</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Bianchi et al., 2003</cut>: <workauthor>Bianchi, E., Denti, S., Catena, R., Rossetti, G., Polo, S., Gasparian, S., Putignano, S., Rogge, L. &amp; Pardi, R.</workauthor>
					<articletitle>Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin </articletitle>
					<articletitle>ligase that interacts with Jun transcription factors and modulates their transcriptional activity</articletitle>. J. Biol. Chem., <number>278</number>, <pages>19682&#8211;19690</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Bounpheng et al., 1999</cut>: <workauthor>Bounpheng, M. A., Dimas, J. J., Dodds, S. G. &amp; Christy, B. A.</workauthor>
					<articletitle>Degradation of Id proteins by the ubiquitin-proteasome pathway</articletitle>. FASEB J., <number>13</number>, <pages>2257&#8211;2264</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Bouvet et al., 1998</cut>: <workauthor>Bouvet, M., Bold, R. J., Lee, J., Evans, D. B., Abbruzzese, J. L., Chiao, P. J., McConkey, D. J., Chandra, J., Chada, S., Fang, B., &amp; Roth, J. A.</workauthor>
					<articletitle>Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer</articletitle>. Ann. Surg. Oncol., <number>5</number>, <pages>681&#8211;688</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Brooks et al., 2000</cut>: <workauthor>Brooks, P., Fuertes, G., Murray, R. Z., Bose, S., Knecht, E., Rechsteiner, M. C., Hendil, K. B., Tanaka, K., Dyson, J. &amp; Rivett, A. J.</workauthor>
					<articletitle>Subcellular localization of proteasomes and their regulatory complexes in mammalian cells</articletitle>. Biochem. J., <number>346</number>, <pages>155&#8211;161</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Bussolino et al</cut>
					<cut>.,</cut>
					<cut> 1997</cut>: <workauthor>Bussolino, F., Mantovani, A. &amp; Persico, G. </workauthor>
					<articletitle>Molecular mechanisms of blood vessel formation</articletitle>. Trends Biochem. Sci., <number>22</number>, <pages>251&#8211;256</pages>, <pubdate>1997</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Chen &amp; Tan, 1998</cut>: <workauthor>Chen, Y.R. &amp; Tan, T. H.</workauthor>
					<articletitle>Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin</articletitle>. Oncogene, <number>17</number>, <pages>173&#8211;178</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Christy et al., 1991</cut>: <workauthor>Christy, B. A., Sanders, L. K., Lau, L. F., Copeland, N. G., Jenkins, N. A. &amp; Nathans, D.</workauthor>
					<articletitle>An ID-related helix-loop-helix protein encoded by a growth factor inducible gene</articletitle>. Proc. Natl. Acad. Sci. USA, <number>88</number>, <pages>1815&#8211;1819.</pages>, <pubdate>1991</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ciechanover, 1994</cut>: <workauthor>Ciechanover A.</workauthor>
					<articletitle>The ubiquitin-proteasome proteolytic pathway</articletitle>. Cell, <number>79</number>, <pages>13&#8211;21</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Claret et al., 1996</cut>: <workauthor>Claret, F. X., Hibi, M., Dhut, S., Toda, T. &amp; Karin, M.</workauthor>
					<articletitle>A new group of conserved coactivators that increase the specifity of AP-1 transcription factors</articletitle>. Nature, <number>383</number>, <pages>453&#8211;457</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Cohen et al., 2000</cut>: <workauthor>Cohen, H., Azriel, A., Cohen, T., Meraro, D., Hashmueli, S., Bech-Otschir, D., Kraft, R., Dubiel, W. &amp; Levi, B. Z.</workauthor>
					<articletitle>Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). </articletitle>
					<articletitle>A possible link between interferon regulatory factor signaling and the COP9/signalosome</articletitle>. J. Biol. Chem., <number>275</number>, <pages>39081&#8211;39089</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Cope et al., 2002</cut>: <workauthor>Cope, G. A., Suh, G. S., Aravind, L., Schwarz, S. E., Zipursky, S. L., Koonin, E. V. &amp; Deshaies, R. J.</workauthor>
					<articletitle>Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1</articletitle>. Science, <number>298</number>, <pages>608&#8211;611</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>de Candia et al., 2003</cut>: <workauthor>de Candia, P., Solit, D. B., Giri, D., Brogi, E., Siegel, P. M., Olshen, A. B., Muller, W. J., Rosen, N. &amp; Benezra, R.</workauthor>
					<articletitle>Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors</articletitle>. Proc. Natl. Acad. Sci. USA, <number>100</number>, <pages>12337&#8211;12342</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Deed et al., 1996</cut>: <workauthor>Deed, R. W., Armitage, S. &amp; Norton, J. D.</workauthor>
					<articletitle>Nuclear localization and regulation of Id protein through an E protein-mediated chaperone mechanism</articletitle>. J. Biol. Chem., <number>271</number>, <pages>23603&#8211;23606</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Deed et al., 1997</cut>: <workauthor>Deed, R. W., Hara, E., Atherton, G. T., Peters, G. &amp; Norton, J. D.</workauthor>
					<articletitle>Regulation of ID3 cell cycle function by Cdk2-dependent phosphorylation</articletitle>. Mol. Cell Biol., <number>17</number>, <pages>6815&#8211;6821</pages>, <pubdate>1997</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Deshaies, 1999</cut>: <workauthor>Deshaies, R. J. </workauthor>
					<articletitle>SCF and Cullin/Ring H2-based ubiquitinligases</articletitle>. Annu. Rev. Cell Dev. Biol., <number>15</number>, <pages>435&#8211;467</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Desprez et al., 1998</cut>: <workauthor>Desprez, P-Y., Lin, C. Q., Thomasset, N., Sympson, C. J., Bissell, M. J. &amp; Campisi, J.</workauthor>
					<articletitle>A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein, ID1</articletitle>. Mol. Cell Biol., <number>18</number>, <pages>4577&#8211;4588</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Devary et al., 1991</cut>: <workauthor>Devary, Y., Gottlieb, R. A., Lau, L. &amp; Karin, M.</workauthor>
					<articletitle>Rapid and preferential activation of the c-jun gene during the mammalian UV response</articletitle>. Mol. Cell. Biol., <number>11</number>, <pages>2804&#8211;2811</pages>, <pubdate>1991</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Dunn et al., 2002</cut>: <workauthor>Dunn, C., Wiltshire, C., MacLaren, A. &amp; Gillespie, D. A.</workauthor>
					<articletitle>Molecular mechanism and biological functions of c-Jun N-terminal kinase signalling via the c-Jun transcription factor</articletitle>. Cell Signal., <number>14</number>, <pages>585&#8211;593</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Eferl &amp; Wagner, 2003</cut>: <workauthor>Eferl, R. &amp; Wagner, E. F.</workauthor>
					<articletitle>AP-1: A double-egded sword in tumorigenesis</articletitle>. Nat. Rev. Cancer, <number>3</number>, <pages>859&#8211;868</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Fajerman et al., 2004</cut>: <workauthor>Fajerman, I., Schwartz, A. L. &amp; Ciechanover, </workauthor>
					<workauthor>A</workauthor>
					<workauthor>.</workauthor>
					<articletitle>Degradation of the Id2 developmental regulator: targeting via N-terminal ubiquitination</articletitle>. Biochem. Biophys. Res. Commun., <number>314</number>, <pages>505&#8211;512</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Fang &amp; Kerppola, 2004</cut>: <workauthor>Fang, D. &amp; Kerppola, T. K.</workauthor>
					<articletitle>Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes</articletitle>. PNAS, <number>101</number>, <pages>14782&#8211;14787</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Fang et al., 2002</cut>: <workauthor>Fang, D., Elly, C., Gao, B., Fang, N., Altman, Y., Joazeiro, C., Hunter, T., Copeland, N., Jenkins, N. &amp; Liu, Y. C.</workauthor>
					<articletitle>Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation</articletitle>. Nat. Immunol., <number>3</number>, <pages>281&#8211;287</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ferrara, 2002</cut>: <workauthor>Ferrara, N.</workauthor>
					<articletitle>VEGF and the quest for tumour angiogenesis factors</articletitle>. Nat. Rev. Cancer, <number>2</number>, <pages>795&#8211;803</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ferrara, 2001</cut>: <workauthor>Ferrara, N.</workauthor>
					<articletitle>Role of vascular endothelial growth factor in regulation of physiological angiogenesis</articletitle>. Am. J. Physiol. Cell Physiol., <number>280</number>, <pages>C1358&#8211;C1366</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ferrara &amp; Henzel, 1989</cut>: <workauthor>Ferrara, N. &amp; Henzel, W. J.</workauthor>
					<articletitle>Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells</articletitle>. Biochem. Biophys. Res. Comm., <number>161</number>, <pages>851&#8211;858</pages>, <pubdate>1989</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ferrara et al., 2003</cut>: <workauthor>Ferrara, N., Gerber, H. P. &amp; LeCouter, J.</workauthor>
					<articletitle>The biology of VEGF and its receptors</articletitle>. Nat. Med., <number>9</number>, <pages>669&#8211;676</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Folkman &amp; Klagsbrun, 1987</cut>: <workauthor>Folkman, J. &amp; Klagsbrun, M.</workauthor>
					<articletitle>Angiogenic factors</articletitle>. Science, <number>235</number>, <pages>442&#8211;447</pages>, <pubdate>1987</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Freilich et al., 1999</cut>: <workauthor>Freilich, S., Oron, E., Kapp, Y., Nevo-Caspi, Y., Orgad, S., Segal, D. &amp; Chamovitz, D.A.</workauthor>
					<articletitle>The COP9 signalosome is essential for development of Drosophila melanogaster</articletitle>. Curr. Biol., <number>9</number>, <pages>1187&#8211;1190</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Fu et al., 2001</cut>: <workauthor>Fu, H., Reis, N., Lee, Y., Glickman, M. H. &amp; Vierstra, R. D.</workauthor>
					<articletitle>Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome</articletitle>. EMBO J., <number>20</number>, <pages>7096&#8211;7107</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Fuchs et al., 1996</cut>: <workauthor>Fuchs, S. Y., Dolan, L., Davis, R. J. &amp; Ronai, Z.</workauthor>
					<articletitle>Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase</articletitle>. Oncogene, <number>13</number>, <pages>1531&#8211;1535</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Glickman et al., 1998</cut>: <workauthor>Glickman, M.H., Rubin, D.M., Coux, O., Wefes, I., Pfeifer, G., Cjeka, Z., Baumeister, W., Fried, V.A. &amp; Finley, D.</workauthor>
					<articletitle>A. subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9 signalosome and eIF3</articletitle>. Cell, <number>94</number>, <pages>615&#8211;623</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Goldberg, 2003</cut>: <workauthor>Goldberg, A. L.</workauthor>
					<articletitle>Protein degradation and protection against misfolded or damaged proteins</articletitle>. Nature, <number>426</number>, <pages>895&#8211;899</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Groisman et al., 2003</cut>: <workauthor>Groisman, R., Polanowska, J., Kuraoka, I., Sawada, J., Saijo, M., Drapkin, R., Kisselev, A.F., Tanaka, K., &amp; Nakatani, Y.</workauthor>
					<articletitle>The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially </articletitle>
					<articletitle>regulated by the COP9 signalosome in response to DNA damage</articletitle>. Cell, <number>113</number>, <pages>357&#8211;367</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Guerra &amp; Issinger, 1999</cut>: <workauthor>Guerra, B. &amp; Issinger, O. G.</workauthor>
					<articletitle>Protein kinase CK2 and its role in cellular proliferation, development and pathology</articletitle>. Electrophoresis, <number>20</number>, <pages>391&#8211;408</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Gupta &amp; Qin, 2003</cut>: <workauthor>Gupta, M. K. &amp; Qin, R. Y.</workauthor>
					<articletitle>Mechanism and its regulation of tumor-induced angiogenesis</articletitle>. World J. Gastroenterol., <number>9</number>, <pages>1144&#8211;1155</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hall et al., 2004</cut>: <workauthor>Hall, M. C., Warren, E. N. &amp; Borchers, C. H.</workauthor>
					<articletitle>Multi-kinase phosphorylation of the APC/C activator Cdh1 revealed by mass spectrometry</articletitle>. Cell Cycle, <number>3</number>, <pages>1278&#8211;1284</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hara et al., 1997</cut>: <workauthor>Hara, E., Hall, M. &amp; Peters, G.</workauthor>
					<articletitle>Cdk2-dependent phosphorylation of ID2 modulates activity of E2A-related transcription factors</articletitle>. EMBO J., <number>16</number>, <pages>101&#8211;110</pages>, <pubdate>1997</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hara et al., 1994</cut>: <workauthor>Hara, E., Yamaguchi, T., Nojima, H., Ide, T., Campisi, J., Okayama, H. &amp; Oda, K.</workauthor>
					<articletitle>Id-related genes encoding HLH proteins are required for G1 progression and are repressed in senescent human fibroblasts</articletitle>. J. Biol. Chem., <number>269</number>, <pages>2139&#8211;2145</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Harari-Steinberg &amp; Chamovitz, 2004</cut>: <workauthor>Harari-Steinberg, O. &amp; Chamovitz, D. A.</workauthor>
					<articletitle>The COP9 signalosome: Mediating Between Kinase Signaling and Protein Degradation</articletitle>. Curr. Protein Pept. Sci., <number>5</number>, <pages>185&#8211;189</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hardtke et al., 2000</cut>: <workauthor>Hardtke, C.S., Gohda, K., Osterlund, M.T., Oyama, T., Okada, K. &amp; Deng, X.W.</workauthor>
					<articletitle>HY5 stability and activity in arabidopsis is regulated by phosphorylation in its COP1 binding domain</articletitle>. EMBO J., <number>19</number>, <pages>4997&#8211;5006</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hasmeda &amp; Polya, 1996</cut>: <workauthor>Hasmeda, M. &amp; Polya, G. M.</workauthor>
					<articletitle>Inhibition of cyclic AMP-dependent protein kinase by curcumin</articletitle>. Phytochemistry, <number>42</number>, <pages>599&#8211;605</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Haworth &amp; Avkiran, 2001</cut>: <workauthor>Haworth, R.S. &amp; Avkiran, M.</workauthor>
					<articletitle>Inhibition of protein kinase D by resveratrol</articletitle>. Biochem. Pharmacol., <number>62</number>, <pages>1647&#8211;1651</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hayami et al., 2005</cut>: <workauthor>Hayami, R., Sato, K., Wu, W., Nishikawa, T., Hiroi, J., Ohtani-Kaneko, R., Fukuda, M. &amp; Ohta, T.</workauthor>
					<articletitle>Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2</articletitle>. Cancer Res., <number>65</number>, <pages>6&#8211;10</pages>, <pubdate>2005</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Henke et al., 1999</cut>: <workauthor>Henke, W., Ferrell, K., Bech-Otschir, D., Seeger, M., Schade, R., Jungblut, P., Naumann, M. &amp; Dubiel, W.</workauthor>
					<articletitle>Comparison of human COP9 signalsome and 26S proteasome lid</articletitle>. Mol. Biol. Rep., <number>26</number>, <pages>29&#8211;34</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Henry et al., 2003</cut>: <workauthor>Henry, T. D., Annex, B. H., McKendall, G. R., Azrin, M. A., Lopez, J. J., Giordano, F. J., Shah, P. K., Willerson, J. T., Benza, R. L., Berman, D. S., Gibson, C. M., Bajamonde, A., Rundle, A. C., Fine, J. &amp; McCluskey, E. R.</workauthor>
					<articletitle>The VIVA trial: Vascular endothilial growth factor in ischemia for vascular angiogenesis</articletitle>. Circulation, <number>107</number>, <pages>1359&#8211;1365</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hershko, 1997</cut>: <workauthor>Hershko A.</workauthor>
					<articletitle>Roles of ubiquitin-mediated proteolysis in cell cycle control</articletitle>. Curr. Opin. Cell. Biol., <number>9</number>, <pages>788&#8211;799</pages>, <pubdate>1997</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hershko &amp; Ciechanover, 1998</cut>: <workauthor>Hershko, A. &amp; Ciechanover, A.</workauthor>
					<articletitle>The ubiquitin system</articletitle>. Annu. Rev. Biochem., <number>67</number>, <pages>425&#8211;479</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Hill et al., 1994</cut>: <workauthor>Hill, C. S., Wynne, J. &amp; Treisman, R.</workauthor>
					<articletitle>Serum-regulated transcription by serum response factor (Srf) - a novel role for the DNA binding domain</articletitle>. EMBO J., <number>13</number>, <pages>5421&#8211;5432</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Huang et al., 1992</cut>: <workauthor>Huang, H. C., Chang, J. H., Tung, S. F., Wu, R. T., Foegh, M. L. &amp; Chu, S. H.</workauthor>
					<articletitle>Immunosuppressive effect of emodin, a free radical generator</articletitle>. Eur. J. Pharmacol., <number>211</number>, <pages>359&#8211;364</pages>, <pubdate>1992</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Huang et </cut>
					<cut>al.,</cut>
					<cut> 1994</cut>: <workauthor>Huang, M. T., Lou, Y. R., Ma, W., Newmark, H. L., Reuhl, K. R. &amp; Conney, A. H. </workauthor>
					<articletitle>Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice</articletitle>. Cancer Res., <number>54</number>, <pages>5841&#8211;5847</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Iavarone et al., 1994</cut>: <workauthor>Iavarone, A., Garg, P., Lasorella, A., Hsu, J. &amp; Israel, M. A.</workauthor>
					<articletitle>The helix-loop-helix protein ID2 enhances cell proliferation and binds to the Retinoblastoma protein</articletitle>. Genes and Dev., <number>8</number>, <pages>1270&#8211;1284</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Johnson et al., 1996</cut>: <workauthor>Johnson, S. E.</workauthor>
					<workauthor>,Wang</workauthor>
					<workauthor>, X., Hardy, S., Taparowsky, E. J. &amp; Konieczny, S. F.</workauthor>
					<articletitle>Casein kinase II increases the transcriptional activities of MRF4 and MyoD independently of their direct phosphorylation</articletitle>. Mol. Cell. Biol., <number>16</number>, <pages>1604&#8211;1613</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Kalebic et al., 1983</cut>: <workauthor>Kalebic, T., Garbisa, S., Glaser, B. &amp; Liotta, L. A.</workauthor>
					<articletitle>Basement membrane collagen: degradation by migrating endothelial cells</articletitle>. Science, <number>221</number>, <pages>281&#8211;283</pages>, <pubdate>1983</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Kapelari et al., 2000</cut>: <workauthor>Kapelari, B., Bech-Otschir, D., Hegerl, R., Schade, R., Dumdey, R. &amp; Dubiel, W.</workauthor>
					<articletitle>Electron microscopy and subunit-subunit interactionstudies reveal a first architecture of COP9 signalosome</articletitle>. J. Mol. Biol., <number>300</number>, <pages>1169&#8211;1178</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Karin, 1995</cut>: <workauthor>Karin, M.</workauthor>
					<articletitle>The regulation of AP-1 activity by mitogen-activated protein kinases</articletitle>. J. Biol. Chem., <number>270</number>, <pages>16483&#8211;16486</pages>, <pubdate>1995</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Karin &amp; Ben-Neriah, 2000</cut>: <workauthor>Karin, M. &amp; Ben-Neriah, </workauthor>
					<workauthor>Y</workauthor>
					<workauthor>.</workauthor>
					<articletitle>Phosphorylation meets ubiquitination: the control of NF-kB activity</articletitle>. Annu. Rev. Immunol., <number>18</number>, <pages>621-663</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Kerbel &amp; Folkman, 2002</cut>: <workauthor>Kerbel, R. &amp; Folkman, J.</workauthor>
					<articletitle>Clinical translation of angiogenesis inhibitors</articletitle>. Nat. Rev. Cancer, <number>2</number>, <pages>727&#8211;739</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Kim et al., 2003</cut>: <workauthor>Kim, J. H., Park, K. C., Chung, S. S., Bang, O. &amp; Chung, C. H.</workauthor>
					<articletitle>Deubiquitinating enzymes as cellular regulators</articletitle>. J Biochem , <number>134</number>, <pages>9&#8211;18</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Krzystolik et al., 2002</cut>: <workauthor>Krzystolik, M. G., Afshari, M. A., Adamis, A. P., Gaudreault, J., Gragoudas, E. S., Michaud, N. A., Li, W., Connolly, E., O'Neill, C. A. &amp; Miller, J. W.</workauthor>
					<articletitle>Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment</articletitle>. Arch. Ophthalmol., <number>120</number>, <pages>338&#8211;</pages>
					<pages>346 </pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Kwok et al., 1999</cut>: <workauthor>Kwok, S. F., Staub, J. M. &amp; Deng, X. W.</workauthor>
					<articletitle>Characterization of two subunits of Arabidopsis 19S proteasome regulatory complex and its possible interaction with the COP9 complex</articletitle>. J. Mol. Biol., <number>285</number>, <pages>85&#8211;95</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lamph et al., 1988</cut>: <workauthor>Lamph, W. W., Wamsley, P., Sassone-Corsi, P. &amp; Verma, I. M.</workauthor>
					<articletitle>Induction of the oncogene jun/AP-1 by serum and TPA</articletitle>. Nature, <number>334</number>, <pages>629&#8211;631</pages>, <pubdate>1988</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lasorella et al., 2000</cut>: <workauthor>Lasorella, A., Noseda, M., Beyna, M., Yokota, Y. &amp; Iavarone, A.</workauthor>
					<articletitle>Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins</articletitle>. Nature, <number>407</number>, <pages>592&#8211;598</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lasorella et al., 2001</cut>: <workauthor>Lasorella, A., Uo, T. &amp; Iavarone, A.</workauthor>
					<articletitle>Id proteins at the cross-road of development and cancer</articletitle>. Oncogene, <number>20</number>, <pages>8326&#8211;8333</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>LeCouter et al., 2001</cut>: <workauthor>LeCouter, J., Kowalski, J., Foster, J., Hass, P., Zhang, Z., Dillard-Telm, L., Frantz, G., Rangell, L., DeGuzman, L., Keller, G. A., Peale, F., Gurney, A., Hillan, K. J. &amp; Ferrara, N.</workauthor>
					<articletitle>Identification of an angiogenic mitogen selective for endocrine gland endothelium</articletitle>. Nature, <number>412</number>, <pages>877&#8211;884</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lee, 2001</cut>: <workauthor>Lee, H. Z.</workauthor>
					<articletitle>Effects and mechanisms of emodin on cell death in humanlung squamous cell carcinoma</articletitle>. Br. J. Pharmacol., <number>134</number>, <pages>11&#8211;20</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lee et al., 1987a</cut>: <workauthor>Lee, W., Haslinger, A., Karin, M. &amp; Tjian, R.</workauthor>
					<articletitle>Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40</articletitle>. Nature, <number>325</number>, <pages>368&#8211;372</pages>, <pubdate>1987</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lee et al., 1987b</cut>: <workauthor>Lee, W., Mitchell, P. &amp; Tjian, R. </workauthor>
					<articletitle>Purified transcription factor AP-</articletitle>
					<articletitle>1 interacts with TPA-inducible enhancer elements</articletitle>. 1987, <number>49</number>, <pages>741&#8211;752</pages>, <pubdate>Cell</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Levy et al., 1995</cut>: <workauthor>Levy, A. P., Levy, N. S., Wegner, S. &amp; Goldberg, M. A.</workauthor>
					<articletitle>Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia</articletitle>. J. Biol. Chem., <number>270</number>, <pages>13333&#8211;13340</pages>, <pubdate>1995</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Li et al., 2004</cut>: <workauthor>Li, H., Gerald, W. L. &amp; Benezra, R.</workauthor>
					<articletitle>Utilization of Bone Marrow-Derived Endothelial Cell Precursors in Spontaneous Prostate Tumors Varies with Tumor Grade</articletitle>. Cancer Res., <number>64</number>, <pages>6137&#8211;6143</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lin et al., 2000</cut>: <workauthor>Lin, C. Q., Singh, J., Murata, K., Itahana, Y., Parrinello, S., Liang, S. H., Gillet, C. E., Campisi, J. &amp; Desprez, P-Y.</workauthor>
					<articletitle>A role for ID1 in the aggressive phenotype and steroid response of human breast cancer cells</articletitle>. Cancer Res., <number>60</number>, <pages>1332&#8211;1340</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lluis et al., 2005</cut>: <workauthor>Lluis, F., Ballestar, E., Suelves, M., Esteller, M. &amp; Munoz-Canoves, P.</workauthor>
					<articletitle>E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription</articletitle>. EMBO J. , <number>24</number>, <pages>974&#8211;984</pages>, <pubdate>2005</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Longo et al</cut>
					<cut>.,</cut>
					<cut> 2002</cut>: <workauthor>Longo, R., Sarmiento, R., Fanelli, M., Capaccetti, B., Gattuso, D. &amp; Gasparini, G.</workauthor>
					<articletitle>Anti-angiogenic therapy: Rationale, challenges </articletitle>
					<articletitle>and</articletitle>
					<articletitle> clinical studies</articletitle>. Angiogenesis, <number>5</number>, <pages>237&#8211;256</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lyapina et al</cut>
					<cut>.,</cut>
					<cut> 2001</cut>: <workauthor>Lyapina, S., Cope, G., Shevchenko, A., Serino, G., Tsuge, T., Zhou, C., Wolf, D. A., Wei, N. &amp; Deshaies, R. J.</workauthor>
					<articletitle>Promotion</articletitle>
					<articletitle> of NEDD-CUL1 conjugate cleavage by COP9 signalosome</articletitle>. Science, <number>292</number>, <pages>1382&#8211;1385</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lyden et al</cut>
					<cut>.,</cut>
					<cut> 2001</cut>: <workauthor>Lyden, D., Hattori, K., Dias, S., Costa, C., Blaikie, P., Butros, L., Chadburn,A., Heissig, B., Marks, W., Witte, L., Wu, Y., Hicklin, D., Zhu, Z., Hackett, N. R., Crystal, R. G., Moore, M. A. S., Hajjar, K. A., Manova, K., Benezra, R. &amp; Rafii, S.</workauthor>
					<articletitle>Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth</articletitle>. Nat. Med., <number>7</number>, <pages>1194&#8211;1201</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Lyden et al</cut>
					<cut>.,</cut>
					<cut> 1999</cut>: <workauthor>Lyden, D., Young, E. Z., Zagzag, D., Yan, W., Gerald, W., O´Reilly, R., Bader, B. L., Hynes, R. O., Zhuang, Y., Manova, K. </workauthor>
					<workauthor>&amp; Benezra, R.</workauthor>
					<articletitle>Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts</articletitle>. Nature, <number>401</number>, <pages>670&#8211;677</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Makinen et al., 2002</cut>: <workauthor>Makinen, K., Manninen, H., Hedman, M., Matsi, P., Mussalo, H., Alhava, E. &amp; Yla-Herttuala, S.</workauthor>
					<articletitle>Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study</articletitle>. Mol. Ther., <number>6</number>, <pages>127&#8211;133</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Malterud et al., 1993</cut>: <workauthor>Malterud, K. E., Farbrot, T. L., Huse, A. E. &amp; Sund, R. B.</workauthor>
					<articletitle>Antioxidantand radical scavenging effects of anthraquinones and anthrones</articletitle>. Pharmacology, <number>47 (Suppl. 1)</number>, <pages>77&#8211;85</pages>, <pubdate>1993</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Massari &amp; Murre, 2000</cut>: <workauthor>Massari, M. E. &amp; Murre, C.</workauthor>
					<articletitle>Helix-loop-lelix proteins: regulators of transcription in eucaryotic organisms</articletitle>. Mol. Cell. Biol., <number>20</number>, <pages>429&#8211;440</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>McNamara et al., 1998</cut>: <workauthor>McNamara, D. A., Harmey, J. H., Walsh, T. N., Redmond, H. P. &amp; Bouchier-Hayes, D. J.</workauthor>
					<articletitle>Significance of angiogenesis in cancer therapy</articletitle>. Br. J. Surg., <number>85</number>, <pages>1044&#8211;1055</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Mullally &amp; Fitzpatrick, 2002</cut>: <workauthor>Mullally, J. E. &amp; Fitzpatrick, F. A.</workauthor>
					<articletitle>Pharmacophore model for novel inhibitors of ubiquitin isopeptidases that induce p53-independent cell death</articletitle>. Mol. Pharmacol., <number>62</number>, <pages>351&#8211;358</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Mundt et al., 1999</cut>: <workauthor>Mundt, K.E., Porte, J., Murray, J.M., Brikos, C., Christensen, P.U., Caspari, T., Hagan, I.M., Millar, J.B., Simanis, V., Hofmann, K. &amp; Carr, A.M.</workauthor>
					<articletitle>The COP9/signalosome complex is conserved in fission yeast and has </articletitle>
					<articletitle>a role in S phase</articletitle>. Curr. Biol., <number>9</number>, <pages>1427&#8211;1430</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Musti et al., 1997</cut>: <workauthor>Musti, A. M., Treier, M. &amp; Bohmann, D</workauthor>
					<articletitle>Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases</articletitle>. Science, <number>275</number>, <pages>400&#8211;402</pages>, <pubdate>1997</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Nagata et al., 1995</cut>: <workauthor>Nagata, Y., Shoji, W., Obinata, M. &amp; Todokoro, K.</workauthor>
					<articletitle>Phosphorylation of helix-loop-helix proteins ID1, ID2 and ID3</articletitle>. Biochem. Biophys. Res. Commun. , <number>207</number>, <pages>916&#8211;926</pages>, <pubdate>1995</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Nateri et al., 2004</cut>: <workauthor>Nateri, A. S., Riera-Sans, L., Da Costa, C. &amp; Behrens, A.</workauthor>
					<articletitle>The Ubiquitin Ligase SCFFbw7 Antagonizes Apoptotic JNK Signaling</articletitle>. Science, <number>303</number>, <pages>1374&#8211;1378</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Naumann et al., 1999</cut>: <workauthor>Naumann, M., Bech-Otschir, D., Huang, X., Ferrell, K. &amp; Dubiel, W.</workauthor>
					<articletitle>COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK</articletitle>. J. Biol. Chem., <number>274</number>, <pages>35297&#8211;35300</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Neufeld et al., 1999</cut>: <workauthor>Neufeld, G., Cohen, T., Gengrinovitch, S. &amp; Poltorak, Z.</workauthor>
					<articletitle>Vascular endothelial growth factor (VEGF) and its receptors</articletitle>. FASEB J., <number>13</number>, <pages>9&#8211;22</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Nordgard et al., 2001</cut>: <workauthor>Nordgard, O., Dahle, O., Andersen, T. O. &amp; Gabrielsen, O. S.</workauthor>
					<articletitle>JAB1/CSN5 interacts with the GAL4 DNA binding domain: a note of caution about two-hybrid interactions</articletitle>. Biochimie, <number>83</number>, <pages>969&#8211;971</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Norton, 2000</cut>: <workauthor>Norton, J. D.</workauthor>
					<articletitle>ID proteins in cell growth, differentiation and tumorigenesis</articletitle>. J. Cell Sci., <number>113</number>, <pages>3897&#8211;3905</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Norton et al., 1998</cut>: <workauthor>Norton, J. D., Craggs, G., Deed, R. W. &amp; Sablitzky, F.</workauthor>
					<articletitle>ID helix-loop-helix proteins in cell growth and differentiation</articletitle>. Trends Cell Biol., <number>8</number>, <pages>58&#8211;65</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Norton &amp; Atherton, 1998</cut>: <workauthor>Norton, J.D. &amp; Atherton, G.T.</workauthor>
					<articletitle>Coupling of cell growth control and apoptosis functions of Id proteins</articletitle>. Mol. Cell. Biol., <number>18</number>, <pages>2371&#8211;2381</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>O´Toole et al., 2003</cut>: <workauthor>O´Toole, P. J., Inoue, T., Emerson, L., Morrison, I. E., Mackie, A. R., Cherry, R. J. &amp; Norton, J. D.</workauthor>
					<articletitle>Id proteins negatively regulate basic helix-loop-helix transcription factor function by disrupting subnuclear compartmentalization</articletitle>. J. Biol. Chem., <number>278</number>, <pages>45770&#8211;45776</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ohtani et al., 2001</cut>: <workauthor>Ohtani, N., Zebedee, Z., Huot, T. J., Stinson, J. A., Sugimoto, M., Ohashi, Y., Sharrocks, A. D., Peters, G. &amp; Hara, E.</workauthor>
					<articletitle>Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence </articletitle>. Nature, <number>409</number>, <pages>1067&#8211;1070</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Osterlund et al., 1999</cut>: <workauthor>Osterlund, M. T., Ang, L. H. &amp; Deng, X. W.</workauthor>
					<articletitle>The role of COP1 in repression of Arabidopsis photomorphogenic development</articletitle>. Trends Cell Biol., <number>9</number>, <pages>113&#8211;118</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Osterlund et al., 2000</cut>: <workauthor>Osterlund, M. T., Hardtke, C. S., Wei, N. &amp; Deng, X. W.</workauthor>
					<articletitle>Targeted destabilization of HY5 during light-regulated development of Arabidopsis</articletitle>. Nature, <number>405</number>, <pages>462&#8211;466</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Park et al., 1998</cut>: <workauthor>Park, S., Lee, D. K. &amp; Yang, C. H.</workauthor>
					<articletitle>Inhibition of fos-jun-DNA complex formation by dihydroguaiaretic acid and in vitro cytotoxic effects on cancer cells</articletitle>. Cancer Lett., <number>127</number>, <pages>23&#8211;28</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Peng et al., 2003</cut>: <workauthor>Peng, Z., Shen, Y., Feng, S., Wang, X., Chitteti, B. N., Vierstra,R. D. &amp; Deng, X. W.</workauthor>
					<articletitle>Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo</articletitle>. Curr. Biol., <number>13</number>, <pages>R504&#8211;R505</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Pickart, 2001</cut>: <workauthor>Pickart, C.M.</workauthor>
					<articletitle>Mechanisms underlying ubiquitination</articletitle>. Annu. Rev. Biochem., <number>70</number>, <pages>503&#8211;533</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Pollmann et al., 2001</cut>: <workauthor>Pollmann, C., Huang, X., Mall, J., Bech-Otschir, D., Naumann, M. &amp; Dubiel, W.</workauthor>
					<articletitle>The constitutive photomorphogenesis 9 </articletitle>
					<articletitle>signalosome directs vascular endothelial growth factor production in tumor cells</articletitle>. Cancer Res., <number>61</number>, <pages>8416&#8211;8421</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Prabhu et al., 1997</cut>: <workauthor>Prabhu, S., Ignatova, A., Park, S. T. &amp; Sun, X-H.</workauthor>
					<articletitle>Regulation of expression of the cyclin dependent kinase inhibitor p21 by E2A and ID proteins</articletitle>. Mol. Cell Biol., <number>17</number>, <pages>5888&#8211;5896</pages>, <pubdate>1997</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Pray et al., 2002</cut>: <workauthor>Pray, T. R., Parlati, F., Huang, J., Wong, B. R., Payan, D. G., Bennett, M. K., Issakani, S. D., Molineaux, S. &amp; Demo, S. D.</workauthor>
					<articletitle>Cell cycle regulatory E3 ubiquitin ligases as anticancer targets</articletitle>. Drug Resist. Updat., <number>5</number>, <pages>249&#8211;258</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Reddy &amp; Lokesh, 1994</cut>: <workauthor>Reddy, A. C. &amp; Lokesh, B. R.</workauthor>
					<articletitle>Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidation of ferrous iron</articletitle>. Mol. Cell. Biochem., <number>137</number>, <pages>1&#8211;8</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Riechmann et al., 1994</cut>: <workauthor>Riechmann, V., van Cruchten, I. &amp; Sablitzky, F.</workauthor>
					<articletitle>The expression pattern of Id4, a novel dominant negative helix-loop-helix protein is distinct from Id1, Id2 and Id3</articletitle>. Nucleic Acids Res., <number>22</number>, <pages>749&#8211;755</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ruzinova &amp; Benezra, 2003</cut>: <workauthor>Ruzinova, M. B. &amp; Benezra, R.</workauthor>
					<articletitle>Id proteins in development, cell cycle and cancer</articletitle>. Trends Cell Biol., <number>13</number>, <pages>410&#8211;418</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Ruzinova et al., 2003</cut>: <workauthor>Ruzinova, M. B., Schoer, R. A., Gerald, W., Egan, J. E., Pandolfi, P. P., Rafii, S., Manova, K., Mittal, V., &amp; Benezra, R.</workauthor>
					<articletitle>Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors</articletitle>. Cancer Cell, <number>4</number>, <pages>277&#8211;289</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sajithlal et al., 1998</cut>: <workauthor>Sajithlal, G. B., Chithra, P. &amp; Chandrakasan, G.</workauthor>
					<articletitle>Effect of curcumin on the advanced glycation and cross-linking of collagen in diabetic rats</articletitle>. Biochem Pharmacol., <number>56</number>, <pages>1607&#8211;1614</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sakurai et al., 2004</cut>: <workauthor>Sakurai, D., Tsuchiya, N., Yamaguchi, A., Okaji, Y., Tsuno, N. H., Kobata, T., Takahashi, K., &amp; Tokunaga, K.</workauthor>
					<articletitle>Crucial Role of Inhibitor of DNA Binding/Differentiation in the Vascular Endothelial Growth Factor-Induced Activation and Angiogenic Processes of Human Endothelial Cells</articletitle>. J. Immunol., <number>173</number>, <pages>5801&#8211;5809</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Scheffner et al., 1993</cut>: <workauthor>Scheffner, M., Huibregtse, J. M., Vierstra, R. D. &amp; Howley, P. M.</workauthor>
					<articletitle>The HPV-16 E6 und E6-AP complex functions as </articletitle>
					<articletitle>a</articletitle>
					<articletitle> ubiquitin-protein ligase complex in the ubiquitination of p53</articletitle>. Cell, <number>75</number>, <pages>495&#8211;505</pages>, <pubdate>1993</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Schwechheimer et al., 2001</cut>: <workauthor>Schwechheimer, C., Serino, G., Callis, J., Crosby, W. L., Lyapina,S., Deshaies, R. J., Gray, W. M., Estelle, M. &amp; Deng, X. W.</workauthor>
					<articletitle>Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response</articletitle>. Science, <number>292</number>, <pages>1379&#8211;1382</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Seeger et al., 1998</cut>: <workauthor>Seeger, M., Kraft, R., Ferrell, K., Bech-Otschir, D., Dumdey, R., Schade, R. &amp; Dubiel, W. </workauthor>
					<articletitle>A noval protein complex involved in signal transduction possessing similarities to 26 S proteasome subunits</articletitle>. FASEB J., <number>12</number>, <pages>469&#8211;478</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Senger et al., 1983</cut>: <workauthor>Senger, D. R., Galli, S. J., Dvorak, A. M., Perruzzi, C. A., Harvey, V. S. &amp; Dvorak, H. F.</workauthor>
					<articletitle>Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid</articletitle>. Science, <number>219</number>, <pages>983&#8211;985</pages>, <pubdate>1983</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Shaulian &amp; Karin, 2001</cut>: <workauthor>Shaulian, E. &amp; Karin, M.</workauthor>
					<articletitle>AP-1 in cell proliferation and survival</articletitle>. Oncogene, <number>20</number>, <pages>2390&#8211;2400</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Shaulian &amp; Karin, 2002</cut>: <workauthor>Shaulian, E. &amp; Karin, M.</workauthor>
					<articletitle>AP-1 as a regulator of cell life and death</articletitle>. Nat. Cell Biol., <number>4</number>, <pages>E131&#8211;E136</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Shaulian et al., 2000</cut>: <workauthor>Shaulian, E., Schreiber, M., Piu, F., Beeche, M., Wagner, E. F. &amp; Karin, M.</workauthor>
					<articletitle>The mammalian UV response: c-Jun induction is required for </articletitle>
					<articletitle>exit from p53-imposed growth arrest</articletitle>. Cell, <number>103</number>, <pages>897&#8211;907</pages>, <pubdate>2000</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Shweiki et al., 1992</cut>: <workauthor>Shweiki, D., Itin, A., Soffer, D. &amp; Keshet, E.</workauthor>
					<articletitle>Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis</articletitle>. Nature, <number>359</number>, <pages>843&#8211;845</pages>, <pubdate>1992</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sikder et al., 2003</cut>: <workauthor>Sikder, H. A., Devlin, M. K., Dunlap, S., Ryu, B. &amp; Alani, R. M.</workauthor>
					<articletitle>Id proteins in cell growth and tumorigenesis</articletitle>. Cancer Cell, <number>3</number>, <pages>525&#8211;530</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sobrero &amp; Bruzzi, 2005</cut>: <workauthor>Sobrero, A. &amp; Bruzzi, P.</workauthor>
					<articletitle>Bevacizumab Plus Fluorouracil: The Value of Being Part of a Developing Story</articletitle>. J. Clin. Oncol., <number>23</number>, <pages>1&#8211;3</pages>, <pubdate>2005</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Spain et al., 1996</cut>: <workauthor>Spain, B. H., Bowdish, K. S., Pacal, A. R., Staub, S. F., Koo, D., Chang, C.-Y., Xie, W., &amp; Colicelli, J.</workauthor>
					<articletitle>Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells</articletitle>. Mol. Cell. Biol., <number>16</number>, <pages>6698&#8211;6706</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sreejayan &amp; Rao, 1994</cut>: <workauthor>Sreejayan und Rao, M. N.</workauthor>
					<articletitle>Curcuminoids as potent inhibitors of lipid peroxidation</articletitle>. J. Pharm. Pharmacol., <number>46</number>, <pages>1013&#8211;1016</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Street et al., 2002</cut>: <workauthor>Street, J., Bao, M., deGuzman, L., Bunting, S., Peale, F. V. Jr., Ferrara, N., Steinmetz, H., Hoeffel, J., Cleland, J. L., Daugherty, A., van Bruggen, N., Redmond, H. P., Carano, R. A. &amp; Filvaroff, E. H.</workauthor>
					<articletitle>Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover</articletitle>. Proc. Natl. Acad. Sci. USA, <number>99</number>, <pages>9656&#8211;9661</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sun et al., 1991</cut>: <workauthor>Sun, X-H., Copeland, N. G., Jenkins, N. &amp; Baltimore, D.</workauthor>
					<articletitle>ID proteins, ID1 and ID2 selectively inhibit DNA binding by one class of helix-loop-helix proteins</articletitle>. Mol. Cell Biol., <number>11</number>, <pages>5603&#8211;5611</pages>, <pubdate>1991</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sun et al., 2002</cut>: <workauthor>Sun, Y., Wilson, M.P. &amp; Majerus, P.W.</workauthor>
					<articletitle>Inositol 1</articletitle>
					<articletitle>,3,4</articletitle>
					<articletitle>-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1</articletitle>. J. Biol. Chem., <number>277</number>, <pages>45759&#8211;45764</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Sunwoo et al., 2001</cut>: <workauthor>Sunwoo, J. B., Chen, Z., Dong, G., Yeh, N., Bancroft, C. C., Sausville, E., Adams, J., Elliott, P. &amp; Van Waes, C.</workauthor>
					<articletitle>Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kB, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma</articletitle>. Clin. Cancer Res., <number>7</number>, <pages>1419&#8211;1428</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Suzuki et al., 2002</cut>: <workauthor>Suzuki, G., Yanagawa, Y., Kwok, S. F., Matsui, M. &amp; Deng, X. W.</workauthor>
					<articletitle>Arabidopsis COP10 is an ubiquitin-conjugating enzyme variant that acts together with COP1 and the COP9 signalosome in repressing photomorphogenesis</articletitle>. Genes &amp; Dev., <number>16</number>, <pages>554&#8211;559</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Tanaka et al., 2001</cut>: <workauthor>Tanaka, K., Kawakami, T., Tateishi, K., Yashiroda, H. &amp; Chiba, T.</workauthor>
					<articletitle>Control of IkappaBalpha proteolysis by the ubiquitin-proteasome pathway</articletitle>. Biochimie, <number>83</number>, <pages>351&#8211;356</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Tomoda et al., 1999</cut>: <workauthor>Tomoda, K., Kubota, Y. &amp; Kato, J.</workauthor>
					<articletitle>Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1</articletitle>. Nature, <number>398</number>, <pages>160&#8211;165</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Tournay &amp; Benezra, 1996</cut>: <workauthor>Tournay, O. &amp; Benezra, R.</workauthor>
					<articletitle>Transcription of the dominant negative helix-loop-helix protein ID1 is regulated by a protein complex containing the immediate early response gene, Egr-1</articletitle>. Mol. Cell Biol., <number>16</number>, <pages>2418&#8211;2430</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Treier et al., 1994</cut>: <workauthor>Treier, M., Staszewski, L. M. &amp; Bohmann, D.</workauthor>
					<articletitle>Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain</articletitle>. Cell, <number>78</number>, <pages>787&#8211;798</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Tsuge et al., 2001</cut>: <workauthor>Tsuge, T., Matsui, M</workauthor>
					<workauthor>.&amp;</workauthor>
					<workauthor> Wei, N.</workauthor>
					<articletitle>The subunit 1 of the COP9 signalosome suppresses gene expression through its N-terminal domain and incorporates into the complex through the PCI domain</articletitle>. J. Mol. Biol., <number>305</number>, <pages>1&#8211;9</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Uhle et al., 2003</cut>: <workauthor>Uhle, S., Medalia, O., Waldron, R., Dumdey, R., Henklein, P., Bech-Otschir, D., Huang, X., Berse, M., Sperling, J., Schade, R. &amp; Dubiel, W.</workauthor>
					<articletitle>Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome</articletitle>. EMBO J., <number>22</number>, <pages>1302&#8211;1312</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>van</cut>
					<cut> Dam &amp; Castellazzi, 2001</cut>: <workauthor>van Dam, H. &amp; Castellazzi, M.</workauthor>
					<articletitle>Distinct roles of Jun:Fos and Jun:ATF dimers in oncogenesis</articletitle>. Oncogene, <number>20</number>, <pages>2453&#8211;2464</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Van Lint et al., 2002</cut>: <workauthor>Van Lint, J., Rykx, A., Maeda, Y., Vantus, T., Sturany, S., Malhotra, V., Vandenheede, J. R. &amp; Seufferlein, T.</workauthor>
					<articletitle>Protein kinase D: an intracellular traffic regulator on the move</articletitle>. Trends Cell. Biol., <number>12</number>, <pages>193&#8211;200</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>van</cut>
					<cut> Straaten et al., 1983</cut>: <workauthor>van Straaten, F., Muller, R., Curran, T., VanBeveren, C. &amp; Verma, I. M.</workauthor>
					<articletitle>Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein</articletitle>. Proc. Natl. Acad. Sci. USA, <number>80</number>, <pages>3183&#8211;3187</pages>, <pubdate>1983</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Volpert et al., 2002</cut>: <workauthor>Volpert, O. V., Pili, R., Sikder, H. A., Nelius, T., Zaichuk, T., Morris, C., Shiflett, C. B., Devlin, M. K., Conant, K. &amp; Alani, R.M.</workauthor>
					<articletitle>Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1</articletitle>. Cancer Cell, <number>2</number>, <pages>473&#8211;483</pages>, <pubdate>2002</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>von</cut>
					<cut> Arnim, 2003</cut>: <workauthor>von Arnim, A. G.</workauthor>
					<articletitle>On again - off again: COP9 signalosome turns the key on protein degradation</articletitle>. Curr. Op. Plant Cell, <number>6</number>, <pages>520&#8211;529</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wei &amp; Deng, 1999</cut>: <workauthor>Wei, N. &amp; Deng, X.-W.</workauthor>
					<articletitle>Making sense of the COP9 signalosome.</articletitle>
					<articletitle> A regulatory protein complex conserved from Arabidopsis tu human</articletitle>. Trends Genet., <number>15</number>, <pages>98&#8211;103</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wei et al., 1994</cut>: <workauthor>Wei, N., Chamovitz, D.A. &amp; Deng, X.W.</workauthor>
					<articletitle>Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development</articletitle>. Cell, <number>78</number>, <pages>117&#8211;124</pages>, <pubdate>1994</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wei et al., 1998</cut>: <workauthor>Wei, N., Tsuge, T., Serino, G., Dohmae, N., Takio, K., Matsui, M. &amp; Deng, X.W.</workauthor>
					<articletitle>The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex</articletitle>. Curr. Biol., <number>8</number>, <pages>919&#8211;922</pages>, <pubdate>1998</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wernert et al., 1999</cut>: <workauthor>Wernert, N., Stanjek, A., Kiriakidis, S., Hügel, A., Jha, H. C., Mazitschek, R. &amp; Giannis, A.</workauthor>
					<articletitle>Inhibierung der Angiogenese in vivo durch ets-1-Antisense-Oligonucleotide - Hemmung der Expression des Ets-1-Transkriptionsfaktors durch das Antibiotikum Fumagillin</articletitle>. Angew. Chem. 1999, 111,, <number>111</number>, <pages>3432&#8211;3435</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wertz et al., 2004</cut>: <workauthor>Wertz, I. E., O'Rourke, K. M., Zhang, Z., Dornan, D., Arnott, D., Deshaies, R. J. &amp; Dixit, V. M.</workauthor>
					<articletitle>Human De-etiolated-1 </articletitle>
					<articletitle>regulates</articletitle>
					<articletitle> c-Jun by assembling a CUL4A ubiquitin ligase</articletitle>. Science, <number>303</number>, <pages>1371&#8211;1374</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wibley et al., 1996</cut>: <workauthor>Wibley, J., Deed, R., Jasiok, M., Douglas, K. &amp; Norton, J.</workauthor>
					<articletitle>A homology model of the Id-3 helix-loop-helix domain as a basis for structure-function predictions</articletitle>. Biochim. Biophys. Acta., <number>1294</number>, <pages>138&#8211;146</pages>, <pubdate>1996</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wilson et al., 2001</cut>: <workauthor>Wilson, M.P., Sun, Y., Cao, L. &amp; Majerus, P.W.</workauthor>
					<articletitle>Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2</articletitle>. J. Biol. Chem., <number>276</number>, <pages>40998&#8211;41004</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Winter et al., 2004</cut>: <workauthor>Winter, M., Milne, D., Dias, S., Kulikov, R., Knippschild, U., Blattner, C. &amp; Meek, D.</workauthor>
					<articletitle>Protein kinase CK1delta phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover</articletitle>. Biochemistry, <number>43</number>, <pages>16356&#8211;16364</pages>, <pubdate>2004</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Wolf et al., 2003</cut>: <workauthor>Wolf, D. A., Zhou, C. &amp; Wee, S.</workauthor>
					<articletitle>The COP9 signalosome: an </articletitle>
					<articletitle>assembly and maintenance platform for cullin ubiquitin ligases</articletitle>
					<articletitle>?</articletitle>. Nat. Cell Biol., <number>5</number>, <pages>1029&#8211;1033</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Yamamoto et al., 2005</cut>: <workauthor>Yamamoto, A., Friedlein, A., Imai, Y., Takahashi, R., Kahle, P. J. &amp; Haass, C.</workauthor>
					<articletitle>Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity</articletitle>. J. Biol. Chem., <number>280</number>, <pages>3390&#8211;3399</pages>, <pubdate>2005</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Yang et al., 2003</cut>: <workauthor>Yang, J. C., Haworth, L., Sherry, R. M., Hwu, P., Schwartzentruber, D. J., Topalian, S. L., Steinberg, S. M., Chen, H. X. &amp; Rosenberg, S. A.</workauthor>
					<articletitle>A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer</articletitle>. N. Engl. J. Med., <number>349</number>, <pages>427&#8211;434</pages>, <pubdate>2003</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Yates et al., 1999</cut>: <workauthor>Yates, P. R., Atherton, G. T., Deed, R. W., Norton, J. D. &amp; Sharrocks, A. D.</workauthor>
					<articletitle>ID helix-loop-helix proteins inhibit nucleoprotein complex formation by the TCF-ETS domain transcription factors</articletitle>. EMBO J., <number>18</number>, <pages>968&#8211;976</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Yokota, 2001</cut>: <workauthor>Yokota, Y.</workauthor>
					<articletitle>Id and development</articletitle>. Oncogene, <number>20</number>, <pages>8290&#8211;8298</pages>, <pubdate>2001</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Yokota et al., 1999</cut>: <workauthor>Yokota, Y., Mansouri, A., Mori, S., Sugawara, S., Adachi, S., Nishikawa, S. &amp; Gruss, P.</workauthor>
					<articletitle>Development of peripheral lymphoid organs and natural killer cells depends on the helix&#8211;loop&#8211;helix inhibitor Id2</articletitle>. Nature, <number>397</number>, <pages>702&#8211;706</pages>, <pubdate>1999</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Zandomeni, 1989</cut>: <workauthor>Zandomeni, R.O.</workauthor>
					<articletitle>Kinetics of inhibition by 5</articletitle>
					<articletitle>,6</articletitle>
					<articletitle>-dichloro-1-beta-Dribofuranosylbenzimidazole on calf thymus casein kinase II</articletitle>. Biochem. J., <number>262</number>, <pages>469&#8211;473</pages>, <pubdate>1989</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Zhang et al., 1995</cut>: <workauthor>Zhang, L., Chang, C. J., Bacus, S. S. &amp; Hung, M. C.</workauthor>
					<articletitle>Suppressed transformation and induced differentiation of HER-2/neu-overexpressing breast cancer cells by emodin</articletitle>. Cancer Res., <number>55</number>, <pages>3890&#8211;3896</pages>, <pubdate>1995</pubdate>. </citation>
			
			
				<citation published="yes" workType="Journal">
					<cut>Zhou et al., 2003</cut>: <workauthor>Zhou, C., Wee, S., Rhee, E., Naumann, M., Dubiel, W. &amp; Wolf, D. A.</workauthor>
					<articletitle>Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p</articletitle>. Mol. Cell., <number>11</number>, <pages>927&#8211;938</pages>, <pubdate>2003</pubdate>. </citation>
			
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