Bruhn, Claudia: Untersuchungen zum genetischen Polymorphismus der humanen Biotransformationsenzyme Glutathion-S-Transferase T1-1 und Arylamin-N-Acetyltransferase 1

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Internet-Adressen

Das „Arylamine N-Acetyltransferase nomenclature committee“ unter Leitung von D. W. Hein veröffentlicht den aktuellen Stand der Benennung von NAT-Allelen bei prokaryotischen und eukaryotischen Organismen unter der Adresse:.

Im Rahmen des Human Genom Projects veröffentlicht das Genomforschungs-Zentrum The Sanger Centre die Lokalisation von Genen auf den bisher sequenzierten Chromosomen unter:.

Unter der Adresse finden sich allgemeine Regeln zur Nomenklatur von Genen sowie zahlreiche Verweise auf verwandte Datenbanken.

Die unter Leitung von V.A. McKusick vom National Center for Biotechnology Information veröffentlichte Datenbank OMIM (Online Mendelian Inheritance in Man) stellt für humane Gene, so auch GSTT1 und NAT1, in Kurzfasssung Daten zur Molekulargenetik, funktionellen und klinischen Relevanz von Allelen mit zahlreichen Literaturverweisen und Verweisen auf andere Datenbanken zusammen:.

Das Enzym-Informationssystem BRENDA ist eine unter der Leitung von Prof. Dr. D. Schomburg am Institut für Biochemie der Universität zu Köln bearbeitete Datenbank. Unter der Adresse: erhält man umfassende Angaben zur Nomenklatur, Isolation, Struktur, Stabilität, zu Reaktionen, Substraten und Inhibitoren von ca. 3500 Enzymen.


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