<?xml version="1.0" encoding="ISO-8859-1"?><cms:container xmlns:cms="http://edoc.hu-berlin.de/diml/module/cms"><cms:document><cms:meta><cms:entry id="front" part="front" ref="front" type="front"/><cms:entry type="title">Gentransfer in korneale Endothelzellen: nicht-virale und virale Ansätze zur Modulation der Endothelzellfunktion und allogenen Immunreaktion</cms:entry><cms:entry type="author">Haike Dannowski</cms:entry><cms:entry id="chapter1" part="chapter1" ref="chapter1" type="chapter">1</cms:entry><cms:entry id="N100B4" part="chapter1" ref="N100B4" type="section">1.1</cms:entry><cms:entry id="N100BE" part="chapter1" ref="N100BE" type="mm">325.5pt#226.5pt</cms:entry><cms:entry id="N100C7" part="chapter1" ref="N100C7" type="subsection">1.1.1</cms:entry><cms:entry id="N100D1" part="chapter1" ref="N100D1" type="mm">307.5pt#272.25pt</cms:entry><cms:entry id="N100FB" part="chapter1" ref="N100FB" type="section">1.2</cms:entry><cms:entry id="N10105" part="chapter1" ref="N10105" type="subsection">1.2.1</cms:entry><cms:entry id="N10117" part="chapter1" ref="N10117" type="subsection">1.2.2</cms:entry><cms:entry id="N1012A" part="chapter1" ref="N1012A" type="mm">338.25pt#226.5pt</cms:entry><cms:entry id="N1013A" part="chapter1" ref="N1013A" type="subsection">1.2.3</cms:entry><cms:entry id="N10158" part="chapter1" ref="N10158" type="subsection">1.2.4</cms:entry><cms:entry id="N10161" part="chapter1" ref="N10161" type="subsection">1.2.5</cms:entry><cms:entry id="N1016F" part="chapter1" ref="N1016F" type="block">1.2.5.1</cms:entry><cms:entry id="N1017F" part="chapter1" ref="N1017F" type="mm">453.75pt#378.75pt</cms:entry><cms:entry id="N10192" part="chapter1" ref="N10192" type="block">1.2.5.2</cms:entry><cms:entry id="N1019F" part="chapter1" ref="N1019F" type="table"/><cms:entry id="N1036F" part="chapter1" ref="N1036F" type="block">1.2.5.3</cms:entry><cms:entry id="N10379" part="chapter1" ref="N10379" type="mm">357pt#226.5pt</cms:entry><cms:entry id="N10386" part="chapter1" ref="N10386" type="block">1.2.5.4</cms:entry><cms:entry id="N103AA" part="chapter1" ref="N103AA" type="mm">453.75pt#157.5pt</cms:entry><cms:entry id="N103B5" part="chapter1" ref="N103B5" type="subsection">1.2.6</cms:entry><cms:entry id="N103C4" part="chapter1" ref="N103C4" type="subsection">1.2.7</cms:entry><cms:entry id="N103C9" part="chapter1" ref="N103C9" type="block">1.2.7.1</cms:entry><cms:entry id="N103DB" part="chapter1" ref="N103DB" type="block">1.2.7.2</cms:entry><cms:entry id="N103EA" part="chapter1" ref="N103EA" type="block">1.2.7.3</cms:entry><cms:entry id="N103F9" part="chapter1" ref="N103F9" type="block">1.2.7.4</cms:entry><cms:entry id="chapter2" part="chapter2" ref="chapter2" type="chapter">2</cms:entry><cms:entry id="N10430" part="chapter2" ref="N10430" type="section">2.1</cms:entry><cms:entry id="N10435" part="chapter2" ref="N10435" type="subsection">2.1.1</cms:entry><cms:entry id="N1043A" part="chapter2" ref="N1043A" type="block">2.1.1.1</cms:entry><cms:entry id="N10455" part="chapter2" ref="N10455" type="block">2.1.1.2</cms:entry><cms:entry id="N1045A" part="chapter2" ref="N1045A" type="subblock">2.1.1.2.1</cms:entry><cms:entry id="N1046F" part="chapter2" ref="N1046F" type="subblock">2.1.1.2.2</cms:entry><cms:entry id="N10478" part="chapter2" ref="N10478" type="subblock">2.1.1.2.3</cms:entry><cms:entry id="N10484" part="chapter2" ref="N10484" type="subblock">2.1.1.2.4</cms:entry><cms:entry id="N10496" part="chapter2" ref="N10496" type="subblock">2.1.1.2.5</cms:entry><cms:entry id="N104A8" part="chapter2" ref="N104A8" type="subblock">2.1.1.2.6</cms:entry><cms:entry id="N104BF" part="chapter2" ref="N104BF" type="subsection">2.1.2</cms:entry><cms:entry id="N104C4" part="chapter2" ref="N104C4" type="block">2.1.2.1</cms:entry><cms:entry id="N104D0" part="chapter2" ref="N104D0" type="block">2.1.2.2</cms:entry><cms:entry id="N104E0" part="chapter2" ref="N104E0" type="subsection">2.1.3</cms:entry><cms:entry id="N104E5" part="chapter2" ref="N104E5" type="block">2.1.3.1</cms:entry><cms:entry id="N104EF" part="chapter2" ref="N104EF" type="table"/><cms:entry id="N105B9" part="chapter2" ref="N105B9" type="subblock">2.1.3.1.1</cms:entry><cms:entry id="N105C5" part="chapter2" ref="N105C5" type="subblock">2.1.3.1.2</cms:entry><cms:entry id="N105CE" part="chapter2" ref="N105CE" type="subblock">2.1.3.1.3</cms:entry><cms:entry id="N105D8" part="chapter2" ref="N105D8" type="block">2.1.3.2</cms:entry><cms:entry id="N105E0" part="chapter2" ref="N105E0" type="subblock">2.1.3.2.1</cms:entry><cms:entry id="N105EB" part="chapter2" ref="N105EB" type="subsection">2.1.4</cms:entry><cms:entry id="N105F0" part="chapter2" ref="N105F0" type="block">2.1.4.1</cms:entry><cms:entry id="N105F9" part="chapter2" ref="N105F9" type="block">2.1.4.2</cms:entry><cms:entry id="N10608" part="chapter2" ref="N10608" type="block">2.1.4.3</cms:entry><cms:entry id="N10612" part="chapter2" ref="N10612" type="subsection">2.1.5</cms:entry><cms:entry id="N10617" part="chapter2" ref="N10617" type="block">2.1.5.1</cms:entry><cms:entry id="N10622" part="chapter2" ref="N10622" type="subblock">2.1.5.1.1</cms:entry><cms:entry id="N1062B" part="chapter2" ref="N1062B" type="subblock">2.1.5.1.2</cms:entry><cms:entry id="N1063E" part="chapter2" ref="N1063E" type="mm">340.5pt#221.25pt</cms:entry><cms:entry id="N1064C" part="chapter2" ref="N1064C" type="block">2.1.5.2</cms:entry><cms:entry id="N10660" part="chapter2" ref="N10660" type="block">2.1.5.3</cms:entry><cms:entry id="N10669" part="chapter2" ref="N10669" type="block">2.1.5.4</cms:entry><cms:entry id="N10683" part="chapter2" ref="N10683" type="block">2.1.5.5</cms:entry><cms:entry id="N10688" part="chapter2" ref="N10688" type="subblock">2.1.5.5.1</cms:entry><cms:entry id="N10697" part="chapter2" ref="N10697" type="subblock">2.1.5.5.2</cms:entry><cms:entry id="N106A6" part="chapter2" ref="N106A6" type="subblock">2.1.5.5.3</cms:entry><cms:entry id="N106B6" part="chapter2" ref="N106B6" type="block">2.1.5.6</cms:entry><cms:entry id="N106C0" part="chapter2" ref="N106C0" type="subsection">2.1.6</cms:entry><cms:entry id="N106CA" part="chapter2" ref="N106CA" type="section">2.2</cms:entry><cms:entry id="N106D2" part="chapter2" ref="N106D2" type="subsection">2.2.1</cms:entry><cms:entry id="N106D7" part="chapter2" ref="N106D7" type="block">2.2.1.1</cms:entry><cms:entry id="N106DE" part="chapter2" ref="N106DE" type="table"/><cms:entry id="N10772" part="chapter2" ref="N10772" type="block">2.2.1.2</cms:entry><cms:entry id="N10779" part="chapter2" ref="N10779" type="table"/><cms:entry id="N10888" part="chapter2" ref="N10888" type="block">2.2.1.3</cms:entry><cms:entry id="N1088F" part="chapter2" ref="N1088F" type="table"/><cms:entry id="N109EC" part="chapter2" ref="N109EC" type="table"/><cms:entry id="N10AFC" part="chapter2" ref="N10AFC" type="table"/><cms:entry id="N10B2C" part="chapter2" ref="N10B2C" type="block">2.2.1.4</cms:entry><cms:entry id="N10B33" part="chapter2" ref="N10B33" type="table"/><cms:entry id="N10C53" part="chapter2" ref="N10C53" type="block">2.2.1.5</cms:entry><cms:entry id="N10C5A" part="chapter2" ref="N10C5A" type="table"/><cms:entry id="N10E6D" part="chapter2" ref="N10E6D" type="block">2.2.1.6</cms:entry><cms:entry id="N10E74" part="chapter2" ref="N10E74" type="table"/><cms:entry id="N10FFC" part="chapter2" ref="N10FFC" type="block">2.2.1.7</cms:entry><cms:entry id="N11003" part="chapter2" ref="N11003" type="table"/><cms:entry id="N110D4" part="chapter2" ref="N110D4" type="block">2.2.1.8</cms:entry><cms:entry id="N110DB" part="chapter2" ref="N110DB" type="table"/><cms:entry id="N11186" part="chapter2" ref="N11186" type="subsection">2.2.2</cms:entry><cms:entry id="N1118D" part="chapter2" ref="N1118D" type="table"/><cms:entry id="N111D2" part="chapter2" ref="N111D2" type="subsection">2.2.3</cms:entry><cms:entry id="N111D9" part="chapter2" ref="N111D9" type="table"/><cms:entry id="N11271" part="chapter2" ref="N11271" type="subsection">2.2.4</cms:entry><cms:entry id="N11278" part="chapter2" ref="N11278" type="table"/><cms:entry id="N113D6" part="chapter2" ref="N113D6" type="subsection">2.2.5</cms:entry><cms:entry id="N113DD" part="chapter2" ref="N113DD" type="table"/><cms:entry id="N1144C" part="chapter2" ref="N1144C" type="subsection">2.2.6</cms:entry><cms:entry id="N11453" part="chapter2" ref="N11453" type="table"/><cms:entry id="N114D7" part="chapter2" ref="N114D7" type="subsection">2.2.7</cms:entry><cms:entry id="N114DE" part="chapter2" ref="N114DE" type="table"/><cms:entry id="N11560" part="chapter2" ref="N11560" type="subsection">2.2.8</cms:entry><cms:entry id="N11567" part="chapter2" ref="N11567" type="table"/><cms:entry id="N115D6" part="chapter2" ref="N115D6" type="subsection">2.2.9</cms:entry><cms:entry id="N115DD" part="chapter2" ref="N115DD" type="table"/><cms:entry id="N1169D" part="chapter2" ref="N1169D" type="subsection">2.2.10</cms:entry><cms:entry id="N116A2" part="chapter2" ref="N116A2" type="block">2.2.10.1</cms:entry><cms:entry id="N116A9" part="chapter2" ref="N116A9" type="table"/><cms:entry id="N117AF" part="chapter2" ref="N117AF" type="table"/><cms:entry id="N117E0" part="chapter2" ref="N117E0" type="table"/><cms:entry id="N1184F" part="chapter2" ref="N1184F" type="block">2.2.10.2</cms:entry><cms:entry id="N11856" part="chapter2" ref="N11856" type="table"/><cms:entry id="N118EE" part="chapter2" ref="N118EE" type="subsection">2.2.11</cms:entry><cms:entry id="N118F5" part="chapter2" ref="N118F5" type="table"/><cms:entry id="N119AE" part="chapter2" ref="N119AE" type="subsection">2.2.12</cms:entry><cms:entry id="N119B5" part="chapter2" ref="N119B5" type="table"/><cms:entry id="N11BC8" part="chapter2" ref="N11BC8" type="subsection">2.2.13</cms:entry><cms:entry id="N11BCF" part="chapter2" ref="N11BCF" type="table"/><cms:entry id="chapter3" part="chapter3" ref="chapter3" type="chapter">3</cms:entry><cms:entry id="N11DB6" part="chapter3" ref="N11DB6" type="section">3.1</cms:entry><cms:entry id="N11DBB" part="chapter3" ref="N11DBB" type="subsection">3.1.1</cms:entry><cms:entry id="N11DC0" part="chapter3" ref="N11DC0" type="block">3.1.1.1</cms:entry><cms:entry id="N11DCD" part="chapter3" ref="N11DCD" type="table"/><cms:entry id="N11F84" part="chapter3" ref="N11F84" type="mm">453.75pt#472.5pt</cms:entry><cms:entry id="N11F94" part="chapter3" ref="N11F94" type="block">3.1.1.2</cms:entry><cms:entry id="N11FA0" part="chapter3" ref="N11FA0" type="mm">453.75pt#629.25pt</cms:entry><cms:entry id="N11FBD" part="chapter3" ref="N11FBD" type="table"/><cms:entry id="N1216F" part="chapter3" ref="N1216F" type="subsection">3.1.2</cms:entry><cms:entry id="N1217C" part="chapter3" ref="N1217C" type="mm">453.75pt#528.75pt</cms:entry><cms:entry id="N12193" part="chapter3" ref="N12193" type="mm">453.75pt#569.25pt</cms:entry><cms:entry id="N12199" part="chapter3" ref="N12199" type="subsection">3.1.3</cms:entry><cms:entry id="N121A3" part="chapter3" ref="N121A3" type="mm">453.75pt#310.5pt</cms:entry><cms:entry id="N121B4" part="chapter3" ref="N121B4" type="section">3.2</cms:entry><cms:entry id="N121B9" part="chapter3" ref="N121B9" type="subsection">3.2.1</cms:entry><cms:entry id="N121D0" part="chapter3" ref="N121D0" type="block">3.2.1.1</cms:entry><cms:entry id="N121E0" part="chapter3" ref="N121E0" type="mm">284.25pt#139.5pt</cms:entry><cms:entry id="N121F4" part="chapter3" ref="N121F4" type="mm">453.75pt#180.75pt</cms:entry><cms:entry id="N1220A" part="chapter3" ref="N1220A" type="block">3.2.1.2</cms:entry><cms:entry id="N12223" part="chapter3" ref="N12223" type="mm">368.25pt#204.75pt</cms:entry><cms:entry id="N1223C" part="chapter3" ref="N1223C" type="block">3.2.1.3</cms:entry><cms:entry id="N12249" part="chapter3" ref="N12249" type="table"/><cms:entry id="N12300" part="chapter3" ref="N12300" type="block">3.2.1.4</cms:entry><cms:entry id="N1231B" part="chapter3" ref="N1231B" type="block">3.2.1.5</cms:entry><cms:entry id="N12320" part="chapter3" ref="N12320" type="subblock">3.2.1.5.1</cms:entry><cms:entry id="N12330" part="chapter3" ref="N12330" type="mm">453.75pt#174.75pt</cms:entry><cms:entry id="N12346" part="chapter3" ref="N12346" type="mm">453pt#224.25pt</cms:entry><cms:entry id="N12354" part="chapter3" ref="N12354" type="block">3.2.1.6</cms:entry><cms:entry id="N12364" part="chapter3" ref="N12364" type="mm">453pt#232.5pt</cms:entry><cms:entry id="N1236E" part="chapter3" ref="N1236E" type="block">3.2.1.7</cms:entry><cms:entry id="N1237E" part="chapter3" ref="N1237E" type="mm">339pt#170.25pt</cms:entry><cms:entry id="N1238F" part="chapter3" ref="N1238F" type="mm">453.75pt#414.75pt</cms:entry><cms:entry id="N123A9" part="chapter3" ref="N123A9" type="mm">374.25pt#177.75pt</cms:entry><cms:entry id="N123BA" part="chapter3" ref="N123BA" type="table"/><cms:entry id="N12429" part="chapter3" ref="N12429" type="block">3.2.1.8</cms:entry><cms:entry id="N12433" part="chapter3" ref="N12433" type="mm">453.75pt#387.75pt</cms:entry><cms:entry id="N12441" part="chapter3" ref="N12441" type="mm">453.75pt#387.75pt</cms:entry><cms:entry id="N1244F" part="chapter3" ref="N1244F" type="subsection">3.2.2</cms:entry><cms:entry id="N1245D" part="chapter3" ref="N1245D" type="block">3.2.2.1</cms:entry><cms:entry id="N1246D" part="chapter3" ref="N1246D" type="mm">399.75pt#261pt</cms:entry><cms:entry id="N12477" part="chapter3" ref="N12477" type="block">3.2.2.2</cms:entry><cms:entry id="N12487" part="chapter3" ref="N12487" type="mm">453pt#222pt</cms:entry><cms:entry id="chapter4" part="chapter4" ref="chapter4" type="chapter">4</cms:entry><cms:entry id="N124B4" part="chapter4" ref="N124B4" type="section">4.1</cms:entry><cms:entry id="N124C1" part="chapter4" ref="N124C1" type="subsection">4.1.1</cms:entry><cms:entry id="N124CC" part="chapter4" ref="N124CC" type="block">4.1.1.1</cms:entry><cms:entry id="N124D5" part="chapter4" ref="N124D5" type="block">4.1.1.2</cms:entry><cms:entry id="N124E1" part="chapter4" ref="N124E1" type="block">4.1.1.3</cms:entry><cms:entry id="N124F0" part="chapter4" ref="N124F0" type="block">4.1.1.4</cms:entry><cms:entry id="N124FF" part="chapter4" ref="N124FF" type="block">4.1.1.5</cms:entry><cms:entry id="N12510" part="chapter4" ref="N12510" type="section">4.2</cms:entry><cms:entry id="N12517" part="chapter4" ref="N12517" type="subsection">4.2.1</cms:entry><cms:entry id="N12537" part="chapter4" ref="N12537" type="block">4.2.1.1</cms:entry><cms:entry id="N12555" part="chapter4" ref="N12555" type="subsection">4.2.2</cms:entry><cms:entry id="N12570" part="chapter4" ref="N12570" type="section">4.3</cms:entry><cms:entry ref="N12593" type="back"/><cms:entry ref="N12595" type="bibliography">Literaturverzeichnis</cms:entry><cms:entry id="N13441" part="N13441" ref="N13441" type="abbreviation">Abkürzungsverzeichnis</cms:entry><cms:entry id="N13448" part="N13441" ref="N13448" type="table"/><cms:entry id="N13B72" part="N13B72" ref="N13B72" type="appendix">Anhang</cms:entry><cms:entry id="N13B74" part="N13B72" ref="N13B74" type="head"/><cms:entry id="N13B77" part="N13B72" ref="N13B77" type="p"/><cms:entry id="N13B7D" part="N13B72" ref="N13B7D" type="p"/><cms:entry id="N13B80" part="N13B72" ref="N13B80" type="p"/><cms:entry id="N13B86" part="N13B72" ref="N13B86" type="p"/><cms:entry id="N13B8C" part="N13B72" ref="N13B8C" type="p"/><cms:entry id="N13B92" part="N13B72" ref="N13B92" type="p"/><cms:entry id="N13B98" part="N13B72" ref="N13B98" type="p"/><cms:entry id="N13B9E" part="N13B72" ref="N13B9E" type="p"/><cms:entry id="N13BA4" part="N13B72" ref="N13BA4" type="p"/><cms:entry id="N13BAC" part="N13B72" ref="N13BAC" type="p"/><cms:entry id="N13BB2" part="N13B72" ref="N13BB2" type="p"/><cms:entry id="N13BB8" part="N13B72" ref="N13BB8" type="p"/><cms:entry id="N13BBB" part="N13B72" ref="N13BBB" type="p"/><cms:entry id="N13BC1" part="N13B72" ref="N13BC1" type="p"/><cms:entry id="N13BC9" part="N13B72" ref="N13BC9" type="p"/><cms:entry id="N13BD2" part="N13B72" ref="N13BD2" type="p"/><cms:entry id="N13BDB" part="N13B72" ref="N13BDB" type="p"/><cms:entry id="N13BE1" part="N13B72" ref="N13BE1" type="p"/><cms:entry id="N13BED" part="N13B72" ref="N13BED" type="p"/><cms:entry id="N13BF5" part="N13B72" ref="N13BF5" type="p"/><cms:entry id="N13BFD" part="N13B72" ref="N13BFD" type="p"/><cms:entry id="N13C03" part="N13B72" ref="N13C03" type="p"/><cms:entry id="N13C09" part="N13B72" ref="N13C09" type="p"/><cms:entry id="N13C12" part="N13B72" ref="N13C12" type="p"/><cms:entry id="N13C1B" part="N13B72" ref="N13C1B" type="p"/><cms:entry id="N13C24" part="N13B72" ref="N13C24" type="p"/><cms:entry id="N13C2A" part="N13B72" ref="N13C2A" type="p"/><cms:entry id="N13C30" part="N13B72" ref="N13C30" type="p"/><cms:entry id="N13C36" part="N13B72" ref="N13C36" type="p"/><cms:entry id="N13C3C" part="N13B72" ref="N13C3C" type="p"/><cms:entry id="N13C4E" part="N13B72" ref="N13C4E" type="p"/><cms:entry id="N13C54" part="N13B72" ref="N13C54" type="p"/><cms:entry id="N13C5B" part="N13C5B" ref="N13C5B" type="acknowledgement">
				Danksagung</cms:entry><cms:entry id="N13C8A" part="N13C8A" ref="N13C8A" type="declaration">
				Selbstständigkeitserklärung</cms:entry><cms:entry part="N12595" type=":current"/><cms:entry type=":lang">de</cms:entry><cms:entry id=":contents" part="front" ref=":contents" type=":contents">Inhaltsverzeichnis</cms:entry><cms:entry type=":help"><url href="http://...">Hilfe</url></cms:entry></cms:meta><cms:content><bibliography id="N12595">
			<head>Literaturverzeichnis</head>
			<citation published="yes" workType="Journal">
				<workauthor>Abehsira-Amar O, Gibert M, Joliy M, Theze J, Jankovic DL</workauthor>
				<pubdate>(1992).</pubdate>
				<articletitle>IL-4 plays a dominant role in the differential development of Th0 into Th1 and Th2 cells.</articletitle> J Immunol.;<volume>148</volume>:<pages>3820-3829</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Aboalchamat B, Engelmann K, Böhnke M, Eggli P, Bednarz J</workauthor>
				<pubdate>(1999).</pubdate>
				<articletitle>Morphological and functional analysis of immortalized human corneal endothelial cells after transplantation.</articletitle> Exp Eye Res.;
				<volume>69</volume>:<pages>547-553</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Abraham JA, Whang JL, Tumolo A, Mergia A, Friedman J, Gospodarowicz D, Fiddes JC</workauthor>
				<pubdate>(1986).</pubdate>
				<articletitle>Human basic fibroblast growth factor: nucleotide sequence and genomic organization</articletitle>
				.EMBO J.;<volume>5</volume>:<pages>2523-2528</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Abraham NG, da Silva JL, Lavrovsky Y, Stoltz RA, Kappas A, Dunn MW, Schwartzman ML</workauthor>
				<pubdate>(1995</pubdate>). <articletitle>Adenovirus-mediated heme oxygenase-1 gene transfer into rabbit ocular tissues.</articletitle> Invest Ophthalmol Vis Sci.;<volume>36</volume>:<pages>2202-2210</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Abul-Hassan K, Walmsley R, Boulton M</workauthor>
				<pubdate>(2000).</pubdate>
				<articletitle>Optimization of non-viral gene transfer to human primary retinal pigment epithelial cells.</articletitle> Curr Eye Res.;
				<volume>20</volume>:<pages>361-366</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Albon J, Tullo AB, Aktar S, Boulton ME</workauthor>
				<pubdate>(2000</pubdate>). <articletitle>Apoptosis in the endothelium of human corneas for transplantation.</articletitle> Invest Ophthalmol Vis Sci.;<volume>41</volume>:<pages>2887-2893</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Alldredge OC, Krachmer JH</workauthor>
				<pubdate>(1981</pubdate>). <articletitle>Clinical types of corneal transplant rejection. Their manifestations, frequency, preoperative correlates, and treatment.</articletitle> Arch Ophthalmol.;<volume>99</volume>:<pages>599-604</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Arancibia-Cárcamo CV, Oral HB, Haskard DO, Larkin DF, George AJ</workauthor> (<pubdate>1998</pubdate>). <articletitle>Lipoadenofection-mediated gene delivery to the corneal endothelium.</articletitle> Transplantation.;<volume>65</volume>:<pages>62-67</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Assouline M, Hutchinson C, Morton K, Mascarelli F, Jeanny JC, Fayein N, Pouliquen Y, Courtois Y</workauthor> (<pubdate>1989</pubdate>). <articletitle>In vivo binding of topically applied human bFGF on rabbit corneal epithelial wound.</articletitle> Growth Factors.;<volume>1</volume>:<pages>251-261</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Bednarz J, Teifel M, Friedl P, Engelmann K</workauthor> (<pubdate>2000)</pubdate>. <articletitle>Immortalization of human corneal endothelial cells using electroporation protocol optimised for human corneal endothelial and human retinal pigment epithelial cells.</articletitle> Acta Ophthalmol Scand.;<volume>78</volume>:<pages>130-136</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Behr JP, Demeneix B, Loeffler JP, Perez-Mutul J</workauthor> (<pubdate>1989</pubdate>). <articletitle>Efficient gene transfer in mammalian primary endocrine cells with lipopolyamine-coated DNA.</articletitle> Proc Natl Acad Sci USA.;<volume>86</volume>:<pages>6982-6986</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Belting M, Petersson P</workauthor> (<pubdate>1999</pubdate>). <articletitle>Protective role for proteoglycan against cationic lipid cytotoxicity allowing optimal transfection efficiency in vitro.</articletitle> Biochem J.;
				<volume>342</volume>:<pages>281-286</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Bergelson JM, Cunningham JA, Droguett G, Kurt-Jones EA, Krithivas A, Hong JS, Horwitz MS, Crowell RL, Finberg RW</workauthor> (<pubdate>1997</pubdate>). <articletitle>Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5.</articletitle> Science.;<volume>275</volume>:<pages>1320-1323</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Blair-Parks K, Weston BC, Dean DA</workauthor>
				<pubdate>(2002</pubdate>). <articletitle>High-level gene transfer to the cornea using electroporation. </articletitle>J Gene Med.;<volume>4</volume>:<pages>92-100</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Blazar BR, Taylor PA, Panoskaltsis-Mortari A, Narula SK, Smith SR, Roncarolo MG, Vallera DA</workauthor> (<pubdate>1998)</pubdate>. <articletitle>Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease. </articletitle>Transplantation.;<volume>66</volume>:<pages>1220-1229</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Boisgerault F, Liu Y, Anosova N, Ehrlich E, Dana MR, Benichou G</workauthor> (<pubdate>2001</pubdate>). <articletitle>Role of CD4+ and CD8+ T cells in allorecognition: lessons from corneal transplantation.</articletitle> J Immunol.;<volume>167</volume>:<pages>1891-1899</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Borras T, Tamm ER, Zigler Jr.JS</workauthor> (<pubdate>1996</pubdate>). <articletitle>Ocular adenovirus gene transfer varies in efficiancy and inflammatory response</articletitle>. Invest Ophthalmol Vis Sci.;<volume>37</volume>:<pages>1282-1293</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Bourne WM, Nelson LR, Hodge DO</workauthor> (<pubdate>1997</pubdate>). <articletitle>Central corneal endothelial cell changes over a ten-year period.</articletitle> Invest Ophthalmol Vis Sci.;<volume>38</volume>:<pages>779-782</pages>. </citation>
			<citation published="yes" workType="Book">
				<workauthor>Brandt C</workauthor> (<pubdate>2003</pubdate>). <articletitle>Retroviral modifizierte, alloantigen-spezifische und vIL-10 transgene T-Lymphozyten als therapeutischer Ansatz im akuten Abstoßungsmodell.</articletitle> Dissertation.</citation>
			<citation published="yes" workType="Misc">
				<workauthor>Bron AJ, Tripathi DM, Tripathi BJ</workauthor> (<pubdate>1997</pubdate>). Wolff&#8217;s anatomy of the eye and orbit, <version>8th edition</version>. <editor>Chapman &amp; Hall Medical</editor>, <address>London</address>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Budenz DL, Bennett J, Alonso L, Maguire A</workauthor> (<pubdate>1995</pubdate>). <articletitle>In vivo gene transfer into murine corneal endothelial and trabecular meshwork cells.</articletitle> Invest Ophthalmol Vis Sci.;<volume>36</volume>:<pages>2211-2215</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Callanan D, Peeler J, Niederkorn JY</workauthor> (<pubdate>1988</pubdate>). <articletitle>Characteristics of rejection of orthotopic corneal allografts in the rat.</articletitle> Transplantation.;<volume>45</volume>:<pages>437-443</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Caruelle D, Groux-Muscatelli B, Gaudric A, Sestier C, Coscas G, Caruelle JP, Barritault D.</workauthor> (<pubdate>1989</pubdate>). <articletitle>Immunological study of acidic fibroblast growth factor (aFGF) distribution in the eye.</articletitle> J Cell Biochem.;<volume>39</volume>:<pages>117-128</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Chen R, Greene EL, Collinsworth G, Grewal JS, Houghton O, Zeng H, Garnovskaya M, Paul RV, Raymond JR.</workauthor> (<pubdate>1999</pubdate>). <articletitle>Enrichment of transiently transfected mesengial cells by cell sorting after cotransfection with GFP.</articletitle> Am J Physiol.;<volume>276</volume>:<pages>F777-F785</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Chomarat P, </workauthor>Banchereau J (1997). An update on interleukin-4 and its receptor. Eur Cytokine Netw.;<volume>8</volume>:<pages>333-344</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Claerhout I</workauthor> (<pubdate>2004</pubdate>). <articletitle>Role of NK cells in rat corneal allograft rejection.</articletitle> Transplantation.; in press.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Comer RM, King WJ, Ardjomand N, Theoharis S, George AJ, Larkin DF</workauthor>
				<pubdate>(2002</pubdate>). <articletitle>Effect of administration of CTLA4-Ig as protein or cDNA on corneal allograft survival.</articletitle> Invest Ophthalmol Vis Sci.;<volume>43</volume>:<pages>1095-1103</pages>. Erratum in: Invest Ophthalmol Vis Sci;<volume>43</volume>:<pages>1701</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Coupland SE, Krause L, Karow AC, Bartlett RR, Lehmann M, Hoffmann F</workauthor> (<pubdate>1995</pubdate>). <articletitle>Delay in corneal allograft rejection due to anti-CD4 antibody given alone and in combination with cyclosporin A and leflunomide.</articletitle> Ger J Ophthalmol.;<volume>4</volume>:<pages>294-301</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Cua DJ, Coffman RL, Stohlman SA</workauthor> (<pubdate>1996</pubdate>
				<articletitle>). Exposure to T helper 2 cytokines in vivo before encounter with antigen selects for T helper subsets via alterations in antigen-presenting cell function.</articletitle> J Immunol.;<volume>157</volume>:<pages>2830-2836</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Dabin I, Courtois Y</workauthor> (<pubdate>1991</pubdate>). <articletitle>Acidic fibroblast growth factor overexpression in corneal epithelial wound healing.</articletitle> Growth Factors.;<volume>5</volume>:<pages>129-139</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Dallman MJ, Larsen CP, Morris PJ</workauthor> (<pubdate>1991</pubdate>). <articletitle>Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction.</articletitle> J Exp Med.;<volume>174</volume>:<pages>493-497</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Dallman MJ</workauthor> (<pubdate>1993</pubdate>). <articletitle>Cytokines as mediators of organ graft rejection and tolerance.</articletitle> Curr Opin Immunol.;<volume>5</volume>:<pages>788-793</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Dana MR, Yamada J, Streilein JW</workauthor> (<pubdate>1997</pubdate>). <articletitle>Topical interleukin 1 receptor antagonist promotes corneal transplant survival.</articletitle> Transplantation.;<volume>63</volume>:<pages>1501-1507</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>David A, Chetritt J, Coupel-Clauce H, Tesson L, Cassard A, Blancho G et al</workauthor> (<pubdate>1997</pubdate>). <articletitle>Adenovirus-mediated gene transfer in rat liver of interleukin 4 but not interleukin 10 produces severe acute hepatitis.</articletitle> Cytokine.;<volume>9</volume>:<pages>818-829</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>David A Coupel-Clauce H, Chetritt J, Tesson L, Cassard A, Charreau B, Soulillou JP, Anegon I.</workauthor> (<pubdate>1998</pubdate>). <articletitle>Anti-adenovirus immune responses in rats are enhanced by interleukin-4 but not interleukin-10 produced by recombinant adenovirus.</articletitle> Hum Gene Ther.;<volume>9</volume>:<pages>1755-1768</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>David A, Chetritt J, Guillot C, Tesson L, Heslan JM, Cuturi MC, Soulillou JP, Anegon I</workauthor>
				<pubdate>(2000</pubdate>). <articletitle>Interleukin-10 produced by recombinant adenovirus prolongs survival of cardiac allografts in rats.</articletitle> Gene Ther.;<volume>7</volume>:<pages>505-510</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>deVries JE</workauthor> (<pubdate>1995</pubdate>). <articletitle>Immunosuppressive and anti-inflammatory properties of interleukin 10.</articletitle> Ann Med.;<volume>27</volume>:<pages>537-541</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>deWaal Malefyt R, Haanen J, Spits H, Roncarolo MG, te Velde A, Figdor C, Johnson K, Kastelein R, Yssel H, deVries JE</workauthor> (<pubdate>1991</pubdate>). <articletitle>Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression</articletitle>. J Exp Med.;<volume>174</volume>:<pages>915-924</pages>.</citation>
			<citation published="yes" workType="Misc">
				<workauthor>deWaal Malefyt R, Moore KW</workauthor> (<pubdate>1998</pubdate>). <articletitle>Interleukin-10</articletitle>. <editor>In Angus T (ed.)</editor> The cytokine handbook. <publisher>Academic press</publisher>: <address>London</address>
				<pages>pp333-364</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Doebis C, Ritter T, Brandt C, Schonberger B, Volk HD, Seifert M</workauthor> (<pubdate>2002</pubdate>). <articletitle>Efficient in vitro transduction of epithelial cells and keratinocytes with improved adenoviral gene transfer for the application in skin tissue engineering. </articletitle>Transpl Immunol.;<volume>9</volume>:<pages>323-329</pages>. </citation>
			<citation published="yes" workType="Misc">
				<cut>EBAA</cut>
				<pubdate>(2002</pubdate>). <editor>Eye bank association of amerika</editor>. www.restoresight.org
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Efrat S, Fejer G, Brownlee M, Horwitz MS</workauthor> (<pubdate>1995</pubdate>). <articletitle>Prolonged survival of pancreatic islet allografts mediated by adenovirus immunoregulatory transgenes. </articletitle>Proc Natl Acad Sci U S A.;<volume>92</volume>:<pages>6947-6951.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Efrat S, Serreze D, Svetlanov A, Post CM, Johnson EA, Herold K, Horwitz M</workauthor> (<pubdate>2001</pubdate>). <articletitle>Adenovirus early region 3(E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice.</articletitle> Diabetes.;<volume>50</volume>:<pages>980-984</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Engelmann K, Böhnke M</workauthor>
				<pubdate>(1990</pubdate>). <articletitle>Human corneal endothelial cells in long-term cultures: The influence of conditions for isolation, selective and normal growth, and the extracellular matrix on proliferation and morphology.</articletitle> Chibret Int J Ophthalmol.;<volume>7</volume>:<pages>3-13</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Engelmann K, Bednarz J, Böhnke M</workauthor>
				<pubdate>(1999</pubdate>). <articletitle>Endothelial cell transplantation and growth behavior of the human corneal endothelium</articletitle>. Ophthalmologe.;<volume>96</volume>:<pages>555-562</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Esch F, Ueno N, Baird F, Hill F, Denoroy L, Ling N, Gospodarowicz D, Guillemin R</workauthor> (<pubdate>1985)</pubdate>. <articletitle>Primary structure of bovine brain acidic fibroblast growth factor (FGF).</articletitle> Biochem Biophys Res Commun.;<volume>133</volume>:<pages>554-562</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Fallaux FJ, Kranenburg O, Cramer SJ, Houweling A, Van Ormondt H, Hoeben RC, Van Der Eb AJ</workauthor> (<pubdate>1996)</pubdate>. <articletitle>Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors. </articletitle>Hum Gene Ther<volume>.;7</volume>:<pages>215-222</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Farhood H, Serbina N, Huang L</workauthor> (<pubdate>1995)</pubdate>. <articletitle>The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer</articletitle>.Biochim Biophys Acta.;<volume>1235</volume>:<pages>289-295</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Fehervari Z, Rayner SA, Oral HB, George AJ, Larkin DF</workauthor> (<pubdate>1997</pubdate>). <articletitle>Gene transfer to ex vivo stored corneas.</articletitle> Cornea.;<volume>16</volume>:<pages>459-464</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Felgner JH, Kumar R, Sridhar CN, Wheeler CJ, Tsai YJ, Border R, Ramsey P, Martin M, Felgner PL</workauthor> (<pubdate>1994</pubdate>). <articletitle>Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations.</articletitle> J Biol Chem.;<volume>269</volume>:<pages>2550-2561</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Fiorentino DF, Zlotnik A, Mosmann TR, Howard M, O'Garra A</workauthor> (<pubdate>1991</pubdate>
				<articletitle>). IL-10 inhibits cytokine production by activated macrophages.</articletitle> J Immunol.;<volume>147</volume>:<pages>3815-3822</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Fiorentino DF, Zlotnik A, Vieira P, Mosmann TR, Howard M, Moore KW, O'Garra A</workauthor> (<pubdate>1991</pubdate>). <articletitle>IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells</articletitle>. J Immunol.;<volume>146</volume>:<pages>3444-3451</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Frueh BE, Böhnke M</workauthor> (<pubdate>1995</pubdate>). <articletitle>Corneal grafting of donor tissue preserved for longer than 4 weeks in organ-culture medium.</articletitle> Cornea.;<volume>14</volume>:<pages>463-466</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Gain P, Thuret G, Chiquet C, Dumollard JM, Mosnier JF, Campos L</workauthor> (<pubdate>2001)</pubdate>. <articletitle>In situ immunohistochemical study of Bcl-2 and heat shock proteins in human corneal endothelial cells during corneal storage.</articletitle> Br J Ophthalmol.;<volume>85</volume>:<pages>996-1000</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Gajewski TF, Fitch FW</workauthor> (<pubdate>1988)</pubdate>. Anti-proliferative effect of IFN-gamma in immune regulation. I. <articletitle>IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.</articletitle> J Immunol.;<volume>140</volume>:<pages>4245-4252</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>George AJ, Arancibia-Carcamo CV, Awad HM, Comer RM, Fehevari Z, King WJ, Kadifachi M, Hudde T, Kerouedan-Lebosse C, Mirza F, Barbaros Oral H, Rayner SA, Tan PH, Tay E, Larkin DF</workauthor> (<pubdate>2000</pubdate>). <articletitle>Gene delivery to the corneal endothelium</articletitle>
				.Am J Respir Crit Care Med.;<volume>162</volume>:<pages>194-200</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Gill TJ, Kunz HW, Misra DN, Hassett ALC</workauthor> (<pubdate>1987</pubdate>). <articletitle>The major histocompatibility complex of the rat.</articletitle> Transplantation.;<volume>43</volume>:<pages>773-785</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Goerdt S, Orfanos CE</workauthor> (<pubdate>1999</pubdate>). <articletitle>Other functions, other genes: alternative activation of antigen-presenting cells</articletitle>. Immunity.;<volume>10</volume>:<pages>137-142</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Gore SM, Vail A, Bradley BA, Rogers CA, Easty DL, Armitage WJ</workauthor> (<pubdate>1995</pubdate>). <articletitle>HLA-DR matching in corneal transplantation. Systematic review of published evidence. Corneal Transplant Follow-up Study Collaborators. </articletitle>Transplantation.;<volume>60</volume>:<pages>1033-1039</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Gospodarowicz D, Mescher AL, Birdwell CR</workauthor> (<pubdate>1977</pubdate>). <articletitle>Stimulation of corneal endothelial cell proliferations in vitro by fibroblast and epidermal growth factors. </articletitle>Exp Eye Res.;<volume>25</volume>:<pages>75-89</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Gospodarowicz D, Greenburg G (</workauthor>
				<pubdate>1979</pubdate>). <articletitle>The effects of epidermal and fibroblast growth factors on the repair of corneal endothelial wounds in bovine corneas maintained in organ culture</articletitle>. Exp Eye Res.;<volume>28</volume>:<pages>147-157</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Gospodarowicz D, Neufeld G, Schweigerer L</workauthor> (<pubdate>1986</pubdate>). <articletitle>Molecular and biological characterization of fibroblast growth factor, an angiogenic factor which also controls the proliferation and differentiation of mesoderm and neuroectoderm derived cells.</articletitle> Cell Differ.;<volume>19</volume>:<pages>1-17</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Graham FL, Smiley J, Russell WC, Nairn R</workauthor>
				<pubdate>(1977</pubdate>). <articletitle>Characteristics of a human cell line transformed by DNA from human adenovirus type 5. </articletitle>J Gen Virol.;<volume>36</volume>:<pages>59-74</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Griffith TS, Brunner T, Fletcher SM, Green DR, Ferguson TA</workauthor> (<pubdate>1995</pubdate>). <articletitle>Fas-ligand-induced apoptosis as a mechanism of immune privilege.</articletitle> Science.;<volume>270</volume>:<pages>1189-1192</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, Roncarolo MG</workauthor> (<pubdate>1997</pubdate>). <articletitle>A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis.</articletitle> Nature.;<volume>389</volume>:<pages>737-742. </pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Guillot C, David A, Coathalem H, Froud D, Tesson L, Moullier P, Le Mauff B, Usal C, Soulillou JP, Cuturi MC, Anegon I</workauthor> (<pubdate>1999)</pubdate>. <articletitle>Adenovirus-mediated cytokine gene transfer in heart allograft transplantation</articletitle>. Biochem Soc Trans.;<volume>27</volume>:<pages>864-869</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Haskova Z, Usiu N, Pepose JS, Ferguson TA, Stuart PM</workauthor> (<pubdate>2000</pubdate>). <articletitle>CD4+ T cells are critical for corneal, but not skin, allograft rejection</articletitle>. Transplantation<volume>.;69</volume>:<pages>483-487</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Hawley-Nelson P, Ciccaroni V, Gebeyehu G, Jessee J</workauthor> (<pubdate>1993</pubdate>). <articletitle>Lipofectamine reagent: a new, higher efficiency polycationic liposome transfection reagent. </articletitle>Focus.;<volume>15</volume>:<pages>73-79.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>He YG, Ross J, Niederkorn JY</workauthor> (<pubdate>1991</pubdate>). <articletitle>Promotion of murine orthotopic corneal allograft survival by systemic administration of anti-CD4 monoclonal antibody.</articletitle> Invest Ophthalmol Vis Sci.;<volume>32</volume>:<pages>2723-2728. </pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>He XY, Chen J, Verma N, Plain K, Tran G, Hall BM</workauthor> (<pubdate>1998)</pubdate>. <articletitle>Treatment with interleukin-4 prolongs allogeneic neonatal heart graft survival by inducing T helper 2 responses.</articletitle> Transplantation.;<volume>65</volume>:<pages>1145-1152</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Hedge S, Niederkorn JY</workauthor> (<pubdate>2000)</pubdate>. <articletitle>The role of cytotoxic T lymphocytes in corneal allograft rejection</articletitle>. Invest Ophthalmol Vis Sci.;<volume>41</volume>:<pages>3341-3347</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Holland EJ, Chan CC, Wetzig RP, Palestine AG, Nussenblatt RB</workauthor> (<pubdate>1991</pubdate>). <articletitle>Clinical and immunohistologic studies of corneal rejection in the rat penetrating keratoplasty model.</articletitle> Cornea.;<volume>10</volume>:<pages>374-380</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Hoppenreijs VP, Pels E, Vrensen GF, Treffers WF</workauthor> (<pubdate>1994</pubdate>). <articletitle>Basic fibroblast growth factor stimulates corneal endothelial cell growth and endothelial wound healing of human corneas.</articletitle>
				Invest Ophthalmol Vis Sci.;<volume>35</volume>:<pages>931-944</pages>.</citation>
			<citation published="yes" workType="Misc">
				<workauthor>Horwitz MS</workauthor> (<pubdate>1990</pubdate>
				<articletitle>). Adenoviridae and their replication</articletitle>. In Virology. <editor>B.N. Fields and D.M. Knipe, editors</editor>. <publisher>Raven Press,</publisher>
				<address>New York</address>. <pages>1679-1721</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Houssaint E, Blanquet PR, Champion-Arnaud P, Gesnel MC, Torriglia A, Courtois Y, Breathnach R</workauthor> (<pubdate>1990</pubdate>). <articletitle>Related fibroblast growth factor receptor genes exist in the human genome</articletitle>. Proc Natl Acad Sci USA.;<volume>87</volume>:<pages>8180-8184</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Huang S, Kamata T, Takada Y, Ruggeri ZM, Nemerow GR</workauthor> (<pubdate>1996</pubdate>). <articletitle>Adenovirus interaction with distinct integrins mediates seperate events in cell entry and gene delivery to hematopoietic cells.</articletitle> J Virol.;<volume>7</volume>:<pages>4502-4505</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Imamura T, Engleka K, Zhan X, Tokita Y, Forough R, Roeder D, Jackson A, Maier JA, Hla T, Maciag T</workauthor>
				<pubdate>(1990).</pubdate>
				<articletitle>Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence.</articletitle> Science.;<volume>249</volume>:<pages>1567-1570.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Jackson A, Friedman S, Zhan X, Engleka KA, Forough R, Maciag T</workauthor>
				<pubdate>(1992).</pubdate> Heat <articletitle>shock induces the release of fibroblast growth factor 1 from NIH 3T3 cells. </articletitle>Proc Natl Acad Sci U S A.;<volume>89</volume>:<pages>10691-10695. </pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Jaye M, Howk R, Burgess W, Ricca GA, Chiu IM, Ravera MW, O'Brien SJ, Modi WS, Maciag T, Drohan WN</workauthor>
				<pubdate>(1986).</pubdate>
				<articletitle>Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization</articletitle>. Science.;<volume>233</volume>:<pages>541-545.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Joo CK, Pepose JS, Stuart PM</workauthor>
				<pubdate>(1995).</pubdate>
				<articletitle>T-cell mediated responses in a murine model of orthotopic corneal transplantation</articletitle>. Invest Ophthalmol Vis Sci.;<volume>36</volume>:<pages>1530-1540</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Josien R, Muschen M, Gilbert E, Douillard P, Heslan JM, Soulillou JP, Cuturi MC</workauthor>
				<pubdate>(1998</pubdate>). <articletitle>Fas ligand, tumor necrosis factor-alpha expression, and apoptosis during allograft rejection and tolerance.</articletitle> Transplantation.;<volume>66</volume>:<pages>887-893</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Joyce NC</workauthor>
				<pubdate>(2003</pubdate>). <articletitle>Proliferative capacity of the corneal endothelium</articletitle>. Prog Ret Eye Res<volume>.;22</volume>:<pages>359-389</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Kato H, Fieblinger C, Ke B, Li J, Volk HD, Busuttil RW, Kupiec-Weglinski JW, Ritter T</workauthor>
				<pubdate>(1999).</pubdate>
				<articletitle>Synergistic effects of cytokine gene transfer in high responder rat renal allograft recipients.</articletitle>
				<articletitle>(Abstract)</articletitle> Transplantation, <volume>67</volume>:<pages>570</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Kato H, Ritter T, Murakami M, Kusano M, Busuttil RW, Kupiec-Weglinski JW</workauthor>
				<pubdate>(2000</pubdate>). <articletitle>Adenovirus-mediated gene transfer of IL-4 prolongs rat renal allograft survival and inhibits the p21ras-activation pathway.</articletitle> Transpl Proceed<volume>.,32</volume>:<pages>245-246</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Kay MA, Glorioso JC, Naldini L</workauthor> (<pubdate>2001</pubdate>
				<articletitle>). Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. </articletitle>Nat Med.;<volume>7</volume>:<pages>2133-2140</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ke B, Ritter T, Kato H, Zhai Y, Li J, Lehmann M, Busuttil RW, Volk HD, Kupiec-Weglinski JW</workauthor>
				<pubdate>(2000).</pubdate>
				<articletitle>Regulatory cells potentiate the efficacy of IL-4 gene transfer by up-regulating Th2-dependent expression of protective molecules in the infectious tolerance pathway in transplant recipients</articletitle>. J Immunol.;<volume>164</volume>
				<pages>:5739-5745</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ke B, Buelow R, Shen XD, Melinek J, Amersi F, Gao F, Ritter T, Volk HD, Busuttil RW, Kupiec-Weglinski JW</workauthor>
				<pubdate>(2002).</pubdate>
				<articletitle>Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway.</articletitle> Hum Gene Ther<volume>.;13</volume>
				<pages>:1189-1199</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Kennedy MK, Picha KS, Shanebeck KD, Anderson DM, Grabstein KH</workauthor>
				<pubdate>(1994</pubdate>
				<articletitle>). </articletitle>
				<articletitle>Interleukin-12 regulates the proliferation of Th1, but not Th2 or Th0, clones.</articletitle>Eur J Immunol.;<volume>24</volume>
				<pages>:2271-2278</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>King WJ, Comer RM, Hudde T, Larkin DF, George AJ</workauthor>
				<pubdate>(2000</pubdate>). <articletitle>Cytokine and chemokine expression kinetics after corneal transplantation. </articletitle>Transplantation.;<volume>70</volume>:<pages>1225-1233</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Klebe S, Sykes PJ, Coster DJ, Krishnan R, Williams KA</workauthor>
				<pubdate>(2001).</pubdate>
				<articletitle>Prolongation of sheep corneal allograft survival by ex vivo transfer of the gene encoding interleukin-10.</articletitle> Transplantation<volume>.;71:</volume>
				<pages>1214-1220</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Kolls J, Peppel K, Silva M, Beutler B</workauthor>
				<pubdate>(1994).</pubdate>
				<articletitle>Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer. </articletitle>Proc Natl Acad Sci U S A.;<volume>91</volume>:<pages>215-219.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Landshman N, Belkin M, Ben-Hanan I, Ben-Chaim O, Assia E, Savion N</workauthor>
				<pubdate>(1987</pubdate>). <articletitle>Regeneration of cat corneal endothelium induced in vivo by fibroblast growth factor. </articletitle>Exp Eye Res.;<volume>45:</volume>
				<pages>805-811</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Larkin DFP</workauthor>
				<pubdate>(1994</pubdate>). <articletitle>Corneal allograft rejection.</articletitle> Br J Ophthalmol<volume>.;78</volume>:<pages>649-652</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Larkin DF, Oral HB, Ring CJ, Lemoine NR, George AJ</workauthor> (<pubdate>1996)</pubdate>. <articletitle>Adenovirus-mediated gene delivery to the corneal endothelium. </articletitle>Transplantation.;<volume>613:</volume>
				<pages>363-370.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Lee ER, Marshall J, Siegel CS, Jiang C, Yew NS, Nichols MR, Nietupski JB, Ziegler RJ, Lane MB, Wang KX, Wan NC, Scheule RK, Harris DJ, Smith AE, Cheng SH</workauthor> (<pubdate>1996).</pubdate>
				<articletitle>Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung. </articletitle>Hum Gene Ther.;<volume>7</volume>:<pages>1701-1717</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Li S, Rizzo MA, Bhattacharya S, Huang L</workauthor> (<pubdate>1998</pubdate>). <articletitle>Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery.</articletitle> Gene Ther.;<volume>5:</volume>
				<pages>930-937</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Lovicu FJ, de Iongh RU, McAvoy JW</workauthor> (<pubdate>1997</pubdate>). <articletitle>Expression of FGF-1 and FGF-2 mRNA during lens morphogenesis, differentiation and growth. </articletitle>Curr Eye Res.;<volume>16</volume>:<pages>222-230.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ma Y, Hurst HE, Fernandez-Botran R</workauthor>
				<pubdate>(1996).</pubdate>
				<articletitle>Soluble cytokine receptors as carrier proteins: effects of soluble interleukin-4 receptors on the pharmacokinetics of murine interleukin-4. </articletitle>J Pharmacol Exp Ther.;<volume>279</volume>:<pages>340-350.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Mascarelli F, Fuhrmann G, Courtois Y</workauthor> (<pubdate>1993).</pubdate>
				<articletitle>aFGF binding to low and high affinity receptors induces both aFGF and aFGF receptor dimerization</articletitle>. Growth Factors.;<volume>8</volume>:<pages>211-233</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Mignatti P, Morimoto T, Rifkin DB</workauthor>
				<pubdate>(1992</pubdate>). <articletitle>Basic fibroblast growth factor, a protein devoid of secretory signal </articletitle>
				<articletitle>sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex</articletitle>. J Cell Physiol.;<volume>151:</volume>
				<pages>81-93.</pages>
			</citation>
			<citation published="yes" workType="Misc">
				<workauthor>Modrow S, Falke D</workauthor>
				<pubdate>(1997</pubdate>). Molekulare Virologie. <publisher>Spektrum Akademischer Verlag GmbH Heidelberg, Berlin, Oxford,</publisher>
				<pages>391-406</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Mosmann TR, Coffman RL</workauthor> (<pubdate>1989</pubdate>). <articletitle>TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.</articletitle> Annu Rev Immunol.;<volume>7</volume>:<pages>145-173.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Mottram PL, Han WR, Purcell LJ, McKenzie IF, Hancock WW</workauthor> (<pubdate>1995</pubdate>). <articletitle>Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and interferon-gamma in long-surviving mouse heart allografts after brief CD4-monoclonal antibody therapy. </articletitle>Transplantation<volume>.;59:</volume>
				<pages>559-565</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Mueller R, Davies JD, Krahl T, Sarvetnick N</workauthor> (<pubdate>1997)</pubdate>. <articletitle>IL-4 expression by grafts from transgenic mice fails to prevent allograft rejection.</articletitle> J Immunol.;
				<volume>159</volume>:<pages>1599-1603.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Nabel EG, Yang ZY, Plautz G, Forough R, Zhan X, Haudenschild CC, Maciag T, Nabel GJ</workauthor> (<pubdate>1993</pubdate>). <articletitle>Recombinant fibroblast growth factor&#8211;1 promotes intimal hyperplasia and angiogenesis in arteries in vivo.</articletitle> Nature.;<volume>362</volume>:<pages>844-846</pages>.</citation>
			<citation published="yes" workType="Misc">
				<workauthor>Nelson D, Cox M</workauthor>
				<pubdate>(2001).</pubdate> Lehninger Biochemie. <version>3. Auflage</version>, <publisher>Springer-Verlag Berlin, Heidelberg, New York.</publisher>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Nickerson P, Pacheco-Silva A, O'Connell PJ, Steurer W, Kelley VR, Strom TB</workauthor>
				<pubdate>(1993</pubdate>). <articletitle>Analysis of cytokine transcripts in pancreatic islet cell allografts during rejection and tolerance induction.</articletitle> Transplant Proc.;<volume>25</volume>:<pages>984-985</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Nickerson P, Steiger J, Zheng XX, Steele AW, Steurer W, Roy-Chaudhury P, Strom TB</workauthor> (<pubdate>1997)</pubdate>. <articletitle>Manipulation of cytokine networks in transplantation: false hope or realistic opportunity for tolerance?</articletitle> Transplantation.;<volume>63</volume>:<pages>489-494</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Niederkorn JY</workauthor>
				<volume> (</volume>
				<pubdate>1999)</pubdate>
				<volume>. </volume>
				<articletitle>Anterior chamber associated immune deviation.</articletitle>
				<volume/>Chem Immunol.;<volume>73:</volume>
				<pages>59-71</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Nishi Y, Hosokawa T, Aoike A, Kawai K, Kamahora T </workauthor>
				<pubdate>(1990</pubdate>). <articletitle>Early development of CD8-negative and CD8-positive MHC-unrestricted cytotoxic cells induced by alloantigen inoculation in mice.</articletitle> Microbiol Immunol.;<volume>34</volume>:<pages>775-785</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Nunez R, Ackermann M, Saeki Y, Chiocca A, Fraefel C</workauthor>
				<pubdate>(2001</pubdate>). <articletitle>Flow cytometric assessment of transduction efficiency and cytotoxicity of Herpes simplex virus type 1-based amplicon vectors.</articletitle> Cytometry.;<volume>44</volume>:<pages>93-99</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Olive M, Eisenlohr L, Flomenberg N, Hsu S, Flomenberg P</workauthor>
				<pubdate>(2002</pubdate>). <articletitle>The adenovirus capsid protein hexon contains a highly conserved human CD4+ T-cell epitope</articletitle>. Hum Gene Ther.;<volume>13:</volume>
				<pages>1167-1178.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Oral HB, Larkin DFP, Fehervari Z, Byrnes AP, Rankin AM, Haskard DO, Wood MJ, Dallman MJ, George AJ </workauthor>
				<pubdate>(1997).</pubdate>
				<articletitle>Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea. </articletitle>Gene Ther.;<volume>4</volume>
				<pages>:639-647</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ornitz D, Yayon A, Flanagan J, Svann C, Levi E, Leder P</workauthor>
				<pubdate>(1992</pubdate>). <articletitle>Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and mitogenesis in whole cells.</articletitle> Mol Cell Biol.;<volume>12</volume>:<pages>240-247</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ornitz DM</workauthor>
				<pubdate>(2000).</pubdate>
				<articletitle>FGFs, heparan sulfate and FGFRs: complex interactions essential for development.</articletitle> Bioessays<volume>.;22:</volume>
				<pages>108-112.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Oshima Y, Sakamoto T, Hisatomi T, Tsutsumi C, Sassa Y, Ishibashi T, Inomata H</workauthor>
				<pubdate>(2002</pubdate>). <articletitle>Targeted gene transfer to corneal stroma in vivo by electric pulses. </articletitle>Exp Eye Res.;<volume>74</volume>:<pages>191-198.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Paul WE</workauthor>
				<pubdate>(1991).</pubdate>
				<articletitle>Interleukin-4: a prototypic immunoregulatory lymphokine.</articletitle> Blood.;<volume>77</volume>:<pages>1859-1870</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Piccotti JR, Chan SY, VanBuskirk AM, Eichwald EJ, Bishop DK</workauthor>
				<pubdate>(1997</pubdate>). <articletitle>Are Th2 helper T lymphocytes beneficial, deleterious, or irrelevant in promoting allograft survival? </articletitle>Transplantation.;<volume>63</volume>:<pages>619-624.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, Steuhl KP, Weidle EG, Lisch W, Thiel HJ</workauthor>
				<pubdate>(1992).</pubdate>
				<articletitle>Corneal graft rejection: incidence, manifestation, and interaction of clinical subtypes.</articletitle> Transplant Proc.;<volume>24</volume>:<pages>2034-2037.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, Milani JK, Dukes A, Chou J, Lutz S, Ruckert D, Thiel HJ, Mondino BJ</workauthor>
				<pubdate>(1995</pubdate>). <articletitle>Effect of topically applied anti-CD4 monoclonal antibodies on orthotopic corneal allografts in a rat model.</articletitle> Invest Ophthalmol Vis Sci.;<volume>36</volume>:<pages>52-61</pages>. </citation>
			<citation published="yes" workType="Misc">
				<workauthor>Pleyer U und Thiel HJ</workauthor>
				<pubdate>(1995).</pubdate>
				<articletitle>Cytotoxic mechanisms in corneal allograft rejection.</articletitle>
				<editor>In: Pleyer U, Schmidt KH, Thiel HJ (Eds.) </editor>Cell and tissue protection in ophthalmology. <publisher>Thieme/Hippokrates,</publisher>
				<address>Stuttgart,</address>
				<pages>pp:71-82.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, Rieck P, Ritter T, Hartmann C</workauthor>
				<pubdate>(1998).</pubdate>
				<articletitle>Immune reaction after penetrating keratoplasty. </articletitle>
				<articletitle>II. Prevention and therapy. </articletitle>Ophthalmologe.;<volume>95:</volume>
				<pages>444-459.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, Bertelmann E, Rieck P, Hartmann C, Volk HD, Ritter T</workauthor>
				<pubdate>(2000).</pubdate>
				<articletitle>Survival of corneal allografts following adenovirus-mediated gene transfer of interleukin-4. </articletitle>Graefe&#8217;s Arch Clin Exp Ophthalmol, <volume>238</volume>:<pages>531-536</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, Dannowski H, Volk HD, Ritter T</workauthor> (<pubdate>2001a)</pubdate>. <articletitle>Corneal allograft rejection: current understanding. I. Immunobiology and basic mechanisms. </articletitle>Ophthalmologica<volume>.;215</volume>:<pages>254-62.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, Groth D, Hinz B, Keil O, Bertelmann E, Rieck P, Reszka R</workauthor>
				<pubdate>(2001b).</pubdate>
				<articletitle>Efficiency and toxicity of liposome-mediated gene transfer to corneal endothelial cells. </articletitle>Exp Eye Res.;<volume>73:</volume>
				<pages>1-7.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, Dannowski H</workauthor> (<pubdate>2002</pubdate>). <articletitle>Delivery of genes via liposomes to corneal endothelial cells.</articletitle> Drug News Perspect.;<volume>15</volume>:<pages>283-289</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Pleyer U, </workauthor>
				<articletitle>Ritter T (2003). Gene therapy in immune-mediated diseases of the eye. Prog</articletitle>Retin Eye Res.;<volume>22:</volume>
				<pages>277-293.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Powrie F, Menon S, Coffman RL</workauthor>
				<pubdate>(1993</pubdate>
				<articletitle>). Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo.</articletitle> Eur J Immunol.;<volume>23</volume>:<pages>2223-2229.</pages>
			</citation>
			<citation published="yes" workType="Journal">Qian Y, Dana MR (<pubdate>2001</pubdate>). <articletitle>Molecular mechanism of immunity in corneal allotransplantation and xenotransplantation</articletitle>. Expert Rev Mol Med.;<volume>3</volume>:<pages>1-21</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Qin L, Chavin KD, Ding Y, Favaro JP, Woodward JE, Lin J, Tahara H, Robbins P, Shaked A, Ho DY, et al.</workauthor>
				<pubdate>(1995).</pubdate>
				<articletitle>Multiple vectors effectively achieve gene transfer in a murine cardiac transplantation model. Immunosuppression with TGF-beta 1 or vIL-10.</articletitle> Transplantation.;<volume>59</volume>:<pages>809-816</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Qin L, Ding Y, Pahud DR, Robson ND, Shaked A, Bromberg JS</workauthor> (<pubdate>1997a)</pubdate>. <articletitle>Adenovirus-mediated gene transfer of viral interleukin-10 inhibits the immune response to both alloantigen and adenoviral antigen</articletitle>. Hum Gene Ther.;<volume>8</volume>:<pages>1365-1374</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Qin L, Ding Y, Pahud DR, Chang E, Imperiale MJ, Bromberg JS</workauthor> (<pubdate>1997b</pubdate>). <articletitle>Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression.</articletitle> Hum Gene Ther.;<volume>8:</volume>
				<pages>2019-2029</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Rayner SA, Larkin DFP, George AJT</workauthor>
				<pubdate>(2001</pubdate>). <articletitle>TNF receptor secretion after ex vivo adenoviral gene transfer to cornea and effect on in vivo graft survival</articletitle>. Invest Ophthalmol Vis Sci.;<volume>42</volume>:<pages>1568-1573.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Redbrake C, Salla S, Frantz A, Reim M</workauthor> (<pubdate>1999</pubdate>). <articletitle>Metabolic changes of the human donor cornea during organ-culture. </articletitle>Acta Ophthalmol Scand.;<volume>77</volume>:<pages>266-272</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Regelin AE, Fankhaenel S, Gürtesch L, Prinz C, von Kiedrowski G, Massing U</workauthor>
				<pubdate>(2000</pubdate>
				<articletitle>). Biophysical and lipofection studies of DOTAP analogs.</articletitle> Biochim Biophys Acta.;<volume>1464:</volume>
				<pages>151-164</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Reinhard T, Hutmacher M, Sundmacher R</workauthor> (<pubdate>1997</pubdate>). <articletitle>Acute and chronic immune reactions after penetrating keratoplasty with normal immune risk</articletitle>. Klin Monatsbl Augenheilkd<volume>.;210</volume>:<pages>139-143</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Rieck P, Oliver L, Engelmann K, Fuhrmann G, Hartmann C, Courtois Y</workauthor> (<pubdate>1995)</pubdate>. <articletitle>The role of exogenous/endogenous basic fibroblast growth factor (FGF2) and transforming growth factor ß (TGF-ß1) on human corneal endothelial cell proliferation in vitro. </articletitle>Exp Cell Res.;<volume>220</volume>:<pages>36-46</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Rieck PW, Gigon M, Jaroszewski J, Pleyer U, Hartmann C</workauthor>
				<pubdate>(2003</pubdate>
				<articletitle>). Increased endothelial survival of organ-cultured corneas stored in FGF-2-supplemented serum-free medium.</articletitle> Invest Ophthalmol Vis Sci.;<volume>44</volume>
				<pages>:3826-3832</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Rinne JR, Stulting RD</workauthor> (<pubdate>1992).</pubdate>
				<articletitle>Current practices in the prevention and treatment of corneal graft rejection.</articletitle> Cornea.;<volume>11:</volume>
				<pages>326-328</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ritter T, Vogt K, Rieck P, Schilling-Schön A, Kolls J, Hartmann C, Volk HD, Pleyer U</workauthor> (<pubdate>1999a</pubdate>). <articletitle>Adenovirus-mediated gene transfer of interleukin-4 to corneal endothelial cells and organ cultured corneas leads to high IL-4 expression.</articletitle> Exp Eye Res.;<volume>69</volume>:<pages>563-568</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ritter T, Risch K, Schroder G, Kolls J, Siegling A, Graser E, Reinke P, Brock J, Lehmann M, Volk HD</workauthor>
				<pubdate>(1999b</pubdate>). <articletitle>Intragraft overexpression of interleukin-4 is neither sufficient nor essential for tolerance induction to cardiac allografts in a high-responder strain combination.</articletitle> Transplantation.;<volume>68</volume>:<pages>1427-1431.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ritter T, Brandt C, Prosch S, Vergopoulos A, Vogt K, Kolls J, Volk HD</workauthor>
				<pubdate>(2000).</pubdate>
				<articletitle>Stimulatory and inhibitory action of cytokines on the regulation of hCMV-IE promoter activity in human endothelial cells. </articletitle>Cytokine.;<volume>12</volume>:<pages>1163-1170</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Ritter T, Lehmann M, Volk HD</workauthor>
				<pubdate>(2002</pubdate>). <articletitle>Improvements in gene therapy: averting the immune response to adenoviral vectors. </articletitle>Bio Drugs.;<volume>16</volume>:<pages>3-10.</pages>
			</citation>
			<citation published="yes" workType="Book">
				<workauthor>Ritter T</workauthor>
				<pubdate>(2003).</pubdate>
				<articletitle>Anti-inflammatorische und zytoprotektive Gentherapie am Beispiel der experimentellen Transplantation.</articletitle> Habilitationsschrift.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Sanger F, Nicklen S, Coulson AR</workauthor>
				<pubdate>(1977).</pubdate>
				<articletitle>DNA-sequencing with chain-terminating inhibitors.</articletitle> Proc Natl Acad Sci USA.;<volume>74</volume>:<pages>5463-5467</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Sano Y, Osawa H, Sotozono C, Kinoshita S</workauthor>
				<pubdate>(1998).</pubdate>
				<articletitle>Cytokine expression during orthotopic corneal allograft rejection in mice.</articletitle> Invest Ophthalmol Vis Sci.;<volume>39</volume>:<pages>1953-1957.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Sawitzki B, Amersi F, Ritter T, Fisser M, Shen XD, Ke B, Busuttil R, Volk HD, Kupiec-Weglinski JW</workauthor>
				<pubdate>(2002).</pubdate>
				<articletitle>Upregulation of Bag-1 by ex vivo gene transfer protects rat livers from ischemia/reperfusion injury</articletitle>. Hum Gene Ther.;<volume>13</volume>:<pages>1495-1504</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Sayegh MH, Akalin E, Hancock WW, Russell ME, Carpenter CB, Linsley PS, Turka LA</workauthor> (<pubdate>1995)</pubdate>. <articletitle>CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2</articletitle>. J Exp Med.;<volume>181</volume>:<pages>1869-1874</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Schilling-Schön A, Pleyer U, Hartmann C, Rieck PW</workauthor> (<pubdate>2000</pubdate>). <articletitle>The role of endogenous growth factors to support corneal endothelial migration after wounding in vitro.</articletitle> Exp Eye Res.;<volume>71</volume>:<pages>583-589.</pages>
			</citation>
			<citation published="yes" workType="Book">
				<workauthor>Schmidt N</workauthor>
				<pubdate>(2004).</pubdate>
				<articletitle>Immunhistologische Untersuchung von infiltrierenden Zellen nach adenoviraler vIL-10-Transduktion in der experimentellen Keratoplastik.</articletitle>(Dissertation in Vorbereitung).</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Slegers TP, Torres PF, Broersma L, van Rooijen N, van Rij G, van der Gaag R</workauthor>
				<pubdate>(2000</pubdate>). <articletitle>Effect of macrophage depletion on immune effector mechanisms during corneal allograft rejection in rats.</articletitle> Invest Ophthalmol Vis Sci.; <volume>41</volume>:<pages>2239-2247.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Slegers TP, van der Gaag R, van Rooijen N, van Rij G, Streilein JW</workauthor>
				<pubdate>(2003).</pubdate>
				<articletitle>Effect of local macrophage depletion on cellular immunity and tolerance evoked by corneal allografts.</articletitle> Curr Eye Res.;<volume>26:</volume>
				<pages>73-79</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Smith DK, Korbutt GS, Suarez-Pinzon WL, Kao D, Rajotte RV, Elliott JF</workauthor>
				<pubdate>(1997</pubdate>). <articletitle>Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice.</articletitle> Transplantation<volume>.; 64</volume>:<pages>1040-1049.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Sorgi FL, Bhattacharya S, Huang L</workauthor>
				<pubdate>(1997).</pubdate>
				<articletitle>Protamine sulfate enhances lipid-mediated gene transfer.</articletitle> Gene Ther.;<volume>4</volume>:<pages>961-968.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Steiger J, Nickerson PW, Steurer W, Moscovitch-Lopatin M, Strom TB</workauthor>
				<pubdate>(1995</pubdate>). <articletitle>IL-2 knockout recipient mice reject islet cell allografts.</articletitle>J Immunol.;<volume>155</volume>:<pages>489-498.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Stein J, Volk HD, Liebenthal C, Kruger DH, Prosch S</workauthor> (<pubdate>1993</pubdate>). <articletitle>Tumor necrosis factor alpha stimulates the activity of the human cytomegalovirus major immediate early enhancer/promoter in immature monocytic cells. </articletitle>J Gen Virol.;<volume>74</volume>:<pages>2333-2338</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Stuart PM, Griffith TS, Usui N, Pepose J, Yu X, Ferguson TA</workauthor>
				<pubdate>(1997</pubdate>). <articletitle>CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. </articletitle>J Clin Invest.;<volume>99</volume>:<pages>396-402</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Stübiger N, Pleyer U, Erb C, Thiel HJ</workauthor>
				<pubdate>(1995</pubdate>). <articletitle>Keratoplasty a chaud.</articletitle> Ophthalmologe.;<volume>92</volume>:<pages>427-432</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Sung RS, Qin L, Bromberg JS</workauthor>
				<pubdate>(2001</pubdate>). <articletitle>TNFalpha and IFNgamma induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression.</articletitle> Mol Ther.;<volume>3</volume>:<pages>757-767</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Swain SL</workauthor>
				<pubdate>(1995</pubdate>). <articletitle>CD4 T cell development and cytokine polarization: an overview</articletitle>. J Leukoc Biol.;<volume>57</volume>:<pages>795-798</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Takeuchi T, Lowry RP, Konieczny B </workauthor>
				<pubdate>(1992</pubdate>). <articletitle>Heart grafts in murine systems: the differential activation of Th2-like effectors in peripheral tolerance.</articletitle> Transplantation<volume>.;53</volume>:<pages>1281-1294.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Takeuchi T, Ueki T, Sunaga S, Ikuta K, Sasaki Y, Li B, Moriyama N, Miyazaki JI, Kawabe K</workauthor>
				<pubdate>(1997</pubdate>). <articletitle>Murine interleukin 4 transgenic heart allograft survival prolonged with down-regulation of the TH1 cytokine mRNA in grafts.</articletitle> Transplantation.;<volume>64</volume>:<pages>152-157.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Tan PH, King WJ, Chen D, Awad HM, Mackett M, Lechler RI, Larkin DFP, George AJT</workauthor>
				<pubdate>(2001).</pubdate>
				<articletitle>Transferrin receptor-mediated gene trasfer to the corneal endothelium.</articletitle> Transplantation.;<volume>74</volume>
				<pages>:552-560.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Tan PH, Manunta M, Ardomand N, Xue SA, Larkin DF, Haskard D, Taylor KM, George AJ </workauthor>
				<pubdate>(2003).</pubdate>
				<articletitle>Antibody targeted gene transfer to endothelium.</articletitle>J Gene Med.;<volume>5:</volume>
				<pages>311-323.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Thanh HN, Murakami A, Fujiki K, Kanai A </workauthor>(<pubdate>2002)</pubdate>. <articletitle>Transferrin-Polyethylenimine conjugate, Fugene6 and Transit-LT as non-viral vectors for gene transfer to the corneal endothelium. </articletitle>Jpn J Ophthalmol.;<volume>46</volume>:<pages>140-146</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Thylefors B, Negrel AD, Pararajasegaram R, Dadzie KY</workauthor>
				<pubdate>(1995).</pubdate>
				<articletitle>Global data on blindness.</articletitle> Bull World Health Organ.;<volume>73</volume>:<pages>115-121.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Torres PF, de Vos AF, van der Gaag R, Martins B, Kijlstra A</workauthor>
				<pubdate>(1996</pubdate>). <articletitle>Cytokine mRNA expression during experimental corneal allograft rejection.</articletitle> Exp Eye Res.;<volume>63:</volume>
				<pages>453-461</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Torres PF, de Vos AF, Martins B, Kijlstra A</workauthor>
				<pubdate>(1999</pubdate>). <articletitle>Interleukin 10 treatment does not prolong experimental corneal allograft survival</articletitle>. Ophthalmic Res.;<volume>31</volume>:<pages>297-303</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Uchida E, Mizuguchi H, Ishii-Watabe A, Hayakawa T</workauthor>
				<pubdate>(2002</pubdate>). <articletitle>Comparison of the efficiency and safety of non-viral vector-mediated gene transfer into a wide range of human cells. </articletitle>Biol Pharm Bull.;<volume>25:</volume>
				<pages>891-897</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Vail A, Gore SM, Bradley BA, Easty DL, Rogers CA, Armitage WJ</workauthor>
				<pubdate>(1994</pubdate>). <articletitle>Influence of donor and histocompatibility factors on corneal graft outcome. </articletitle>Transplantation.;<volume>58</volume>:<pages>1210-1216.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Verma IM, Somia N</workauthor> (<pubdate>1997</pubdate>). <articletitle>Gene therapy -- promises, problems and prospects.</articletitle> Nature.;<volume>389</volume>:<pages>239-242</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Wackenheim-Urlacher A, Kantelip B, Falkenrodt A, Piqot X, Tongio MM, Montard M, Delbosc B</workauthor>
				<pubdate>(1995).</pubdate>
				<articletitle>T-cell repertoire of normal, rejected, and pathological corneas: phenotype and function.</articletitle> Cornea.;<volume>14</volume>:<pages>450-456.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Wiedlocha A, Falnes PO, Rapak A, Munoz R, Klingenberg O, Olsnes S</workauthor>
				<pubdate>(1996).</pubdate>
				<articletitle>Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization. </articletitle>Mol Cell Biol.;<volume>16</volume>:<pages>270-280.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Williams KA, Coster DJ</workauthor>
				<pubdate>(1997).</pubdate>
				<articletitle>Rethinking immunological privilege: implications for corneal and limbal stem cell transplantation. </articletitle>Mol Med Today.;<volume>3:</volume>
				<pages>495-501.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Wilson SE, Schultz GS, Chegini N, Weng J, He YG</workauthor>
				<pubdate>(1994</pubdate>). <articletitle>Epidermal growth factor, transforming growth factor alpha, transforming growth factor beta, acidic fibroblast growth factor, basic fibroblast growth factor, and interleukin-1 proteins in the cornea. </articletitle>Exp Eye Res.;<volume>59</volume>:<pages>63-72.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Wold WS, Gooding LR</workauthor>
				<pubdate>(1991</pubdate>). <articletitle>Region E3 of adenovirus: a cassette of genes involved in host immunosurveillance and virus-cell interactions.</articletitle> Virology.;<volume>184</volume>:<pages>1-8.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Xu Y, Szoka FC Jr.</workauthor>
				<pubdate>(1996</pubdate>). <articletitle>Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. </articletitle>Biochemistry.;<volume>35</volume>:<pages>5616-5623.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Yamada J, Yoshida M, Taylor AW, Streilein JW</workauthor>
				<pubdate>(1999</pubdate>). <articletitle>Mice with Th2-biased immune systems accept orthotopic corneal allografts placed in high risk eyes.</articletitle> J Immunol.;<volume>162:</volume>
				<pages>5247-5255.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Yamada J, Ksander BR, Streilein JW</workauthor>
				<pubdate>(2001).</pubdate>
				<articletitle>Cytotoxic T cells play no essential role in acute rejection of orthotopic corneal allografts in mice. </articletitle>Invest Ophthalmol Vis Sci.;<volume>42:</volume>
				<pages>386-392.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Yamagami S, Kawashima H, Tsuru T, Yamagami H, Kayagaki N, Yagita H, Okumura K, Gregerson DS </workauthor>
				<pubdate>(1997).</pubdate>
				<articletitle>Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants.</articletitle> Transplantation<volume>.;64:</volume>
				<pages>1107-1111.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Yamagami S, Kawashima H, Endo H, Tsuru T, Shibui H, Kagawa Y, Hori J, Yamagami H, Isobe M</workauthor>
				<pubdate>(1998).</pubdate>
				<articletitle>Cytokine profiles of aqueous humor and graft in orthotopic mouse corneal transplantation.</articletitle> Transplantation.;<volume>66</volume>: <pages>1504-1510</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Yang J, Reutzel-Selke A, Steier C, Jurisch A, Tullius SG, Sawitzki B, Kolls J, Volk HD, Ritter T</workauthor>
				<pubdate>(2003).</pubdate>
				<articletitle>Targeting of macrophage activity by adenovirus-mediated intragraft overexpression of TNFRp55-Ig, IL-12p40, and vIL-10 ameliorates adenovirus-mediated chronic graft injury, whereas stimulation of macrophages by overexpression of IFN-gamma accelerates chronic graft injury in a rat renal allograft model. </articletitle>J Am Soc Nephrol.;<volume>14</volume>:<pages>214-225. </pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Yang J, Pleyer U, Dannowski H, Vogt K, Hempel M, Volk HD, Ritter T</workauthor>
				<pubdate>(2004).</pubdate>
				<articletitle>Effects of local interleukin-12p40 gene therapy on rat corneal allograft survival.</articletitle> (zur Veröffentlichung eingereicht).</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Yang Y, Ertl HCJ, Wilson J</workauthor> (<pubdate>1994).</pubdate>
				<articletitle>MHC class-I restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infectedet with E1-deleted recombinant adenovirus.</articletitle>Immunity.;<volume>1</volume>:<pages>433-442</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ</workauthor>
				<pubdate>(1995).</pubdate>
				<articletitle>Cellular and molecular barriers to gene transfer by a cationic lipid.</articletitle>J Biol Chem.;<volume>270</volume>:<pages>18997-19007</pages>. </citation>
			<citation published="yes" workType="Journal">
				<workauthor>Zhan X, Hu X, Friedman S, Maciag T</workauthor>
				<pubdate>(1992</pubdate>). <articletitle>Analysis of endogenous and exogenous nuclear translocation of fibroblast growth factor-1 in NIH 3T3 cells.</articletitle> Biochem Biophys Res Commun.;<volume>188:</volume>
				<pages>982-991.</pages>
			</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Zhou XH, Huang L (</workauthor>
				<pubdate>1994).</pubdate>
				<articletitle>DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action.</articletitle> Biochim Biophys Acta.;<volume>1189</volume>:<pages>195-203</pages>.</citation>
			<citation published="yes" workType="Journal">
				<workauthor>Zuo Z, Wang C, Carpenter D, Okada Y, Nicolaidou E, Toyoda M, Trento A, Jordan SC</workauthor>
				<pubdate>(2001).</pubdate>
				<articletitle>Prolongation of allograft survival with viral IL-10 transfection in a highly histoincompatible model of rat heart allograft rejection.</articletitle> Transplantation<volume>.;71</volume>:<pages>686-691</pages>. </citation>
		</bibliography></cms:content></cms:document></cms:container>