Albertini RJ (2001) HPRT mutations in humans: biomarkers for mechanistic studies. Mutat Res 489: 1-16

Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, Eperon IC, Nierlich DP, Roe BA, Sanger F, Schreier PH, Smith AJ, Staden R, Young IG (1981) Sequence and organization of the human mitochondrial genome Nature 290: 457-65

Attardi G, Yoneda M, Chomyn A (1995) Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems. Biochim Biophys Acta 1271: 241-8

Augenlicht LH, Heerdt BG (2001) Mitochondria: integrators in tumorigenesis? Nature Genet 28: 104-5

Backer JM, Weinstein IB (1986) p21 ras proteins and guanine nucleotides modulate the phosphorylation of 36- and 17-kilodalton mitochondria-associated proteins. Proc Natl Acad Sci U S A 83: 6357-61

Bandy B, Davison AJ (1990) Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radicals Biol Med 8: 523–539

Basu TN , Gutmann DH, Fletcher JA, Glover TW, Collins FS, Downward J (1992) Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients. Nature 356: 713-5

Bauer M, Lubs H, Lubs ML (1988) Variable expressivity of neurofibromatosis-1 in identical twins. Neurofibromatosis 1: 323-9

Bendall KE, Macaulay VA , Baker JR, Sykes BC (1996) Heteroplasmic point mutations in the human mtDNA control region. Am J Hum Genet 59: 1276-87

Bodyak ND, Nekhaeva E, Wei JY, Khrapko K (2001) Quantification and sequencing of somatic deleted mtDNA in single cells: evidence for partially duplicated mtDNA in aged human tissues. Hum Mol Genet 10: 17-24

Bogenhagen D, Clayton DA (1977) Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle. Cell 11: 719-27

Bowmaker M, Yang MY, Yasukawa T, Reyes A, Jacobs HT, Hubermann JA, Holt IJ (2003) Mammalian mitochondrial DNA replicates bidirectionally from an initiation zone. J Biol Chem 278: 50961-69

Budowle B, Allard MW, Wilson MR, Chakraborty R (2003) Forensics and mitochondrial DNA: applications, debates, and foundations. Annu Rev Genomics Hum Genet 4: 119-41

Burgart LJ, Zheng J, Shu Q, Strickler JG, Shibata D (1995) Somatic mitochondrial mutation in gastric cancer. Am J Pathol 147: 1105-11

Carelli V, Giordano C, D’Amati, G (2003) Pathogenic expression of homoplasmic mtDNA mutations needs a complex nuclear-mitochondrial interaction. Trends in Genetics 19: 257-62

Cawthon RM, Weiss R, Xu GF, Viskochil D, Culver M, Stevens J, Robertson M, Dunn D, Gesteland R, O'Connell P, et al. (1990) A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations. Cell 62: 193-201

Chen JZ, Gokden N, Greene GF, Green B, Kadlubar FF (2003) Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis. Carcinogenesis 24: 1481-87

Cichowski K, Shih TS, Schmitt E, Santiago S, Reilly K, McLaughlin ME, Bronson RT, Jacks T (1999) Mouse models of tumor development in Neurofibromatosis Type 1. Science 286: 2172-76

Clayton DA (1982) Replication of animal mitochondrial DNA. Cell 28: 693-705

Coller HA, Khrapko K, Bodyak ND , Nekhaeva E, Herrero-Jimenez P, Thilly WG (2001) High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat Genet 28: 147-50

Coller HA, Bodyak ND , Khrapko K (2002) Frequent intracellular clonal expansions of somatic mtDNA mutations: significance and mechanisms. Ann N Y Acad Sci 959: 434-47

Colman SD , Williams A, Wallace MR (1995) Benign neurofibromas in type 1 neurofibromatosis (NF1) show somatic deletions of the NF1 gene. Nature Genetics 11: 90-2

Cummins JM (2000) Fertilization and elimination of the paternal mitochondrial genome. Hum Reprod15 Suppl 2: 92-101

Daschner K, Assum G, Eisenbarth I, Krone W, Hoffmeyer S, Wortmann S, Heymer B, Kehrer-Sawatzki H (1997) Clonal origin of tumor cells in a plexiform neurofibroma with LOH in NF1 intron 38 and in dermal neurofibromas without LOH of the NF1 gene. Biochem Biophys Res Commun234: 346-50

Davis AF, Clayton DA (1996) In situ localization of mitochondrial DNA replication in intact mammalian cells. J Cell Biol 135: 883-93

DeClue JE, Papageorge AG, Fletcher JA, Diehl SR, Ratner N, Vass WC, Lowy DR (1992) Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell 69: 265-73

DiMauro S, Andreu AL (2000) Mutations in mtDNA: are we scraping the bottom of the barrel? Brain Pathol 10: 431-41

Dublin S, Riccardi VM, Stephens K (1995) Methods for rapid detection of a recurrent nonsense mutation and documentation of phenotypic features in neurofibromatosis type 1 patients. Hum Mutat 5: 81-5

Dunbar DR, Moonie PA, Jacobs HT, Holt IJ (1995) Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes. Proc Natl Acad Sci U S A92: 6562-66

Easton DF, Ponder MA, Huson SM, Ponder BA (1993) An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes. Am J Hum Genet 53: 305-13

Eisenbarth I, Beyer K, Krone W, Assum G (2000) Toward a survey of somatic mutation of the NF1 gene in benign neurofibromas of patients with neurofibromatosis type 1. Am J Hum Genet 66: 393-401

Fliss MS, Usadel H, Caballero OL, Wu L, Buta MR, Eleff SM, Jen J, Sidransky D (2000) Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287: 2017-19

Friedman JM (1999) Epidemiology of neurofibromatosis type 1. Am J Med Genet89: 1-6

Friedman JM, Birch PH (1997) Type 1 neurofibromatosis: a descriptive analysis of the disorder in 1,728 patients. Am J Med Genet 70: 138-43

Golubic M, Tanaka K, Dobrowolski S, Wood D, Tsai MH, Marshall M, Tamanoi F, Stacey DW (1991) The GTPase stimulatory activities of the neurofibromatosis type 1 and the yeast IRA2 proteins are inhibited by arachidonic acid. Embo J 10: 2897-903

Gutmann DH, Aylsworth A, Carey JC, Korf B, Marks J, Pyeritz RE, Rubenstein A, Viskochil D (1997) The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2. Jama 278: 51-7

Gutmann DH, Collins FS (1993) The neurofibromatosis type 1 gene and its protein product, neurofibromin. Neuron 10: 335-43

Ha PK, Tong BC, Westra WH, Sanchez-Cespedes M, Parrella P, Zahurak M, Sidransky D, Califano JA (2002) Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation. Clin Cancer Res 8: 2260-65

Habano W, Nakamura S, Sugai T (1998) Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome. Oncogene 17: 1931-37

Hauswirth WW, Laipis PJ (1982) Mitochondrial DNA polymorphism in a maternal lineage of Holstein cows. Proc Natl Acad Sci U S A 79: 4686-90

Holt IJ, Harding AE, Morgan-Hughes JA (1988) Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature 331: 717-19

Holt IJ, Lorimer HE, Jacobs HT (2000) Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA. Cell 100: 515-24

Hope DG, Mulvihill JJ (1981) Malignancy in neurofibromatosis. Adv Neurol 29: 33-56

Horan MP, Cooper DN, Upadhyaya M (2000) Hypermethylation of the neurofibromatosis type 1 (NF1) gene promoter is not a common event in the inactivation of the NF1 gene in NF1 specific tumors. Hum Genet 107: 33-39

Horton TM, Petros JA, Heddi A, Shoffner J, Kaufman AE, Graham SD, Gramlich T, Wallace DC (2000) Novel mitochondrial DNA deletion found in a renal cell carcinoma. Genes Chromosomes Cancer 15: 95-101

Howell N, Chinnery PF, Ghosh SS, Fahy E, Turnbull DM (2000a) Transmission of the human mitochondrial genome. Hum Reprod 15 Suppl 2: 235-45

Howell N, Ghosh SS, Fahy E, Bindoff LA (2000b) Longitudinal analysis of the segregation of mtDNA mutations in heteroplasmic individuals. J Neurol Sci172: 1-6

Jansen RP, de Boer K (1998) The bottleneck: mitochondrial imperatives in oogenesis and ovarian follicular fate. Mol Cell Endocrinol 145: 81-8

Jansen RP (2000) Germline passage of mitochondria: quantitative considerations and possible embryological sequelae. Hum Reprod 15 Suppl 2: 112-28

Jenuth JP, Peterson AC, Fu K, Shoubridge EA (1996) Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA. Nat Genet 14: 146-51

Jenuth JP, Peterson AC, Shoubridge EA (1997) Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice. Nat Genet 16: 93-5

Jones JB, Song JJ, Hempen PM, Parmigiani G, Hruban RH, Kern SE (2001) Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations. Cancer Res 61: 1299-304

Jones PA, Laird PW (1999) Cancer epigenetics comes of age. Nature Genet 21: 163-67

Khrapko K, Nekhaeva E, Kraytsberg Y, Kunz W (2003) Clonal expansions of mitochondrial genomes: implications for in vivo mutational spectra. Mutat Res522: 13-9

Kirches E, Michael M, Warich-Kirches M, Schneider T, Weis S, Krause G, Mawrin C, Dietzmann K (2001a) Heterogeneous tissue distribution of a mitochondrial DNA polymorphism in heteroplasmic subjects without mitochondrial disorders. J Med Genet 38: 312-17

Kirches E, Krause G, Warich-Kirches M, Weis S, Schneider T, Meyer-Puttlitz B, Mawrin C, Dietzmann K (2001b) High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples. Int J Cancer 93: 534-38

Kirches E, Krause G, Weis S, Mawrin C, Dietzmann K (2002) Comparison between mitochondrial DNA sequences in low grade astrocytomas and corresponding blood samples. Mol Pathol 55: 204-6

Klose A, Ahmadian MR, Schuelke M, Scheffzek K, Hoffmeyer S, Gewies A, Schmitz F, Kaufmann D, Peters H, Wittinghofer A, Nurnberg P (1998) Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1. Hum Mol Genet 7: 1261-68

Kluwe L, Friedrich R, Mautner VF (1999) Loss of NF1 allele in Schwann cells but not in fibroblasts derived from an NF1-associated neurofibroma. Genes Chromosomes Cancer 24: 283-5

Knudson AG, Jr. (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 68: 820-23

Koehler CM, Lindberg GL, Brown DR, Beitz DC, Freeman AE, Mayfield JE, Myers AM (1991) Replacement of bovine mitochondrial DNA by a sequence variant within one generation. Genetics 129: 247-55

Kösel S, Grasbon-Frodl EM, Hagenah JM, Graeber MB, Vieregge P (2000) Parkinson disease: analysis of mitochondrial DNA in monozygotic twins. Neurogenetics 2: 227-30

Krone W, Kehrer-Sawatzki H (2001) Neurofibromatose Typ 1 in Ganten D und Ruckpaul K (Hrsg.) Molekularmedizinische Grundlagen von hereditären Tumorerkrankungen. Springer-Verlag 90-163

Kunkel TA, Loeb LA (1981) Fidelity of mammalian DNA polymerases. Science 213: 765-67

Lagerstrom-Fermer M, Olsson C, Forsgren L, Syvanen AC (2001) Heteroplasmy of the human mtDNA control region remains constant during life. Am J Hum Genet 68: 1299-301

Larsson NG, Barsh GS, Clayton DA (1997) Structure and chromosomal localization of the mouse mitochondrial transcription factor A gene (Tfam). Mamm Genome 8: 139-40

Legius E, Marchuk D, Collins FS Glover TW (1993) Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis. Nature Genetics 3: 122-26

Liu VW, Yang HJ, Wang Y, Tsang PC, Cheung AN, Chiu PM, Ng TY, Wong LC, Nagley P, Ngan HY (2003) High frequency of mitochondrial genome instability in human endometrial carcinomas. Br J of Cancer 89: 697-701

Listernick R, Louis DN, Packer RJ, Gutmann DH (1997) Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force. Ann Neurol 41: 143-49

Malik S, Sudoyo H, Pramoonjago P, Suryadi H, Sukarna T, Njunting M, Sahiratmadja E, Marzuki S (2002) Nuclear mitochondrial interplay in the modulation of the homopolymeric tract length heteroplasmy in the control (D-loop) region of the mitochondrial DNA. Hum Genet 110: 402-11

Mancini DN, Singh SM, Archer TK, Rodenhiser DI (1999) Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors. Oncogene 18: 4108-19

Margulis L (1975) Symbiotic theory of the origin of eucaryotic organelles; criteria for proof. Exp Soc Biol 29: 21-38

Martin GA, Viskochil D, Bollag G, McCabe PC, Crosier WJ, Haubruck H, Conroy L, Clark R, O'Connell P, Cawthon RM, et al. (1990) The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21. Cell 63: 843-49

Miller M, Hall JG (1978) Possible maternal effect on severity of neurofibromatosis. Lancet 2: 1071-73

Monnat RJ, Jr., Loeb LA (1985) Nucleotide sequence preservation of human mitochondrial DNA. Proc Natl Acad Sci U S A 82: 2895-99

Muller HJ (1964) The Relation of Recombination to Mutational Advance. Mutat Res106: 2-9

Mullis KB and Faloona F (1987) Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol 155: 335-50

Nass S, Nass MM (1963) Intramitochondrial Fibers with DNA Characteristics. Ii. Enzymatic and Other Hydrolytic Treatments. J Cell Biol 19: 613-29

Nekhaeva E, Kraytsberg Y, Khrapko K (2002a) mtLOH (mitochondrial loss of heteroplasmy), aging, and 'surrogate self'. Mech Ageing Dev 123: 891-98

Nekhaeva E, Bodyak ND, Kraytsberg Y, McGrath SB, Van Orsouw NJ, Pluzhnikov A, Wei JY, Vijg J, Khrapko K (2002b) Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues. Proc Natl Acad Sci U S A 99: 5521-26

Newton CR, Graham A (1994) PCR, 2. Auflage. Spektrum, Akademischer Verlag.

NIH (1988) Neurofibromatosis. Conference statement. National Institutes of Health Consensus Development Conference. Arch Neurol 45: 575-78

North KN, Riccardi V, Samango-Sprouse C (1997) Cognitive function and academic performance in neurofibromatosis 1: consensus statement from the NF1 Cognitive Disorders Task Force. Neurology48: 1121-27

Oberley LW, Buettner GR (1979) Role of superoxide dismutase in cancer: a review. Cancer Res 39: 1141-49

Parrella P, Seripa D, Matera MG, Rabitti C, Rinaldi M, Mazzarelli P, Gravina C, Gallucci M, Altomare V, Flammia G, Casalino B, Benedetti-Panici PL, Fazio VM (2003) Mutations of the D310 mitochondrial mononucleotide repeat in primary tumors and cytological specimens. Cancer Lett 190: 73-77

Pedersen PL (1978) Tumor mitochondria and the bioenergetics of cancer cells. Prog Exp Tumor Res 22: 190-274

Polyak K, Li Y, Zhu H, Lengauer C, Willson JK, Markowitz SD, Trush MA, Kinzler KW, Vogelstein B (1998) Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat Genet 20: 291-93

Rasmussen SA, Friedman JM (2000) NF1 gene and neurofibromatosis 1. Am J Epidemiol 151: 33-40

Recklinghausen F (1882) Über die multiplen Fibrome der Haut und ihre Beziehung zu den multiplen Neuromen. Berlin , Hirschwald

Riccardi VM (2000) Histogenesis control genes and neurofibromatosis 1. Eur J Pediatr159: 475-76

Roudebush M, Slabe T, Sundaram V, Hoppel CL, Golubic M, Stacey DW (1997) Neurofibromin colocalizes with mitochondria in cultured cells. Exp Cell Res 236: 161-72

Sanchez-Cespedes M, Parrella P, Nomoto S, Cohen D, Xiao Y, Esteller M, Jeronimo C, Jordan RC, Nicol T, Koch WM, Schoenberg M, Mazzarelli P, Fazio VM, Sidransky D (2001) Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors. Cancer Res 61: 7015-19

Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463-67

Schuelke M, Bakker M, Stoltenburg G, Sperner J, von Moers A (1998) Epilepsia partialis continua associated with a homoplasmic mitochondrial tRNA(Ser(UCN)) mutation. Ann Neurol 44: 700-4

Schwartz M, Vissing J (2002) Paternal inheritance of mitochondrial DNA. N Engl J Med347: 576-80

Serra E, Ars E, Ravella A, Sánchez A, Puig S, Rosenbaum T, Estivil X, Lázaro C (2001) Somatic NF1 mutational spectrum in benign neurofibromas: mRNA splice defects are common among point mutations. Hum Genet 108: 416-29

Shay JW, Ishii S (1990) Unexpected nonrandom mitochondrial DNA segregation in human cell hybrids. Anticancer Res 10: 279-84

Stephens K, Kayes L, Riccardi VM, Rising M, Sybert VP, Pagon RA (1992) Preferential mutation of the neurofibromatosis type 1 gene in paternally derived chromosomes. Hum Genet 88: 279-82

Tamura G, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Sakata K, Endoh Y and Motoyama T (1999) Mutations in mitochondrial control region DNA in gastric tumors of Japanese patients. Eur J Cancer 35: 316-319

Taylor RW, Barron MJ, Borthwick GM, Gospel A, Chinnery PF, Samuels DC, Taylor GA, Plusa SM, Needham SJ, Greaves LC, Kirkwood TB, Turnbull DM (2003) Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Invest 112: 1351-60

Tourmen Y, Baris O, Dessen P, Jacques C, Malthiery Y, Reynier P (2002) Structure and chromosomal distribution of human mitochondrial pseudogenes. Genomics 80: 71-7

Upadhyaya M, Cheryson A, Broadhead W, Fryer A, Shaw DJ, Huson S, Wallace MR, Andersen LB, Marchuk DA, Viskochil D, et al. (1990) A 90 kb DNA deletion associated with neurofibromatosis type 1. J Med Genet 27: 738-41

Upadhyaya M, Ruggieri M, Maynard J, Osborn M, Hartog C, Mudd S, Penttinen M, Cordeiro I, Ponder M, Ponder BA, Krawczak M, Cooper DN (1998) Gross deletions of the neurofibromatosis type 1 (NF1) gene are predominantly of maternal origin and commonly associated with a learning disability, dysmorphic features and developmental delay. Hum Genet102: 591-97

Vega A, Salas A, Gamborino E, Sobrido MJ, Macaulay V, Carracedo A (2004) mtDNA mutations in tumors of the central nervous system reflect the neutral evolution of mtDNA in populations. Oncogene 23: 1314-20

Viskochil D, Buchberg AM, Xu G, Cawthon RM, Stevens J, Wolff RK, Culver M, Carey JC, Copeland NG, Jenkins NA, et al. (1990) Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus. Cell 62: 187-92

Vogel KS , Brannan CI, Jenkins NA, Copeland NG and Parada LF (1995) Loss of neurofibromin results in neurotropin-independant survival of embryonic sensory and sympathetic neurons. Cell 82: 733-42

Wallace DC, Singh G, Lott MT, Hodge JA, Schurr TG, Lezza AM, Elsas LJ, 2nd, Nikoskelainen EK (1988) Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 242: 1427-30

Wallace MR, Marchuk DA, Anderson LB, Letcher R, Odeh HM, Saulino AM, Fountain JW, Brereton A, Nicholson J, Mitchell AL, Brownstein BH, Collins FS (1990) Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. Science 249: 181-86

Wallace DC (1995) 1994 William Allan Award Address. Mitochondrial DNA variation in human evolution, degenerative disease, and aging. Am J Hum Genet 57: 201-23

Wang Y, Michikawa Y, Mallidis C, Bai Y, Woodhouse L, Yarasheski KE, Miller CA, Askanas V, Engel WK, Bhasin S, Attardi G (2001) Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication. Proc Natl Acad Sci U S A98: 4022-27

Wiest V, Eisenbarth I, Schmegner C, Krone W, Assum G (2003) Somatic NF1 Mutation Spectra in a Family With Neurofibromatosis Type 1: Toward a Theory of Genetic Modifiers. Hum Mutat 22: 423-27

Wilkie D, Evans IH, Egilsson V, Diala ES, Collier D (1983) Mitochondria, cell surface, and carcinogenesis. Int Rev Cytol Suppl 15: 157-89

Xu GF, O'Connell P, Viskochil D, Cawthon R, Robertson M, Culver M, Dunn D, Stevens J, Gesteland R, White R, et al. (1990) The neurofibromatosis type 1 gene encodes a protein related to GAP. Cell 62: 599-608

Yoneda M, Chomyn A, Martinuzzi A, Hurko O, Attardi G (1992) Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy. Proc Natl Acad Sci U S A 89: 11164-68

Zöller M, Rembeck B, Akesson HO (1997) Life expectancy, mortality and prognostic factors in neurofibromatosis type 1: a twelve-year follow-up of an epidemiological study in Göteborg , Sweden . Acta Derm Venereol 75: 136-40

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