Funktionelle Analyse der Phytochrome Cph1 und Cph2 von Synechocystis sp. PCC 6803Brita FiedlerZusammenfassung111.121.21.2.134580#2475586#1611.2.261.2.37891.31.3.11011586#4071.3.212593#5901.3.313600#24314151.4161718191.5201.62122.12.1.1212.1.2222.1.32.1.4232.1.52.1.6242.1.72.1.82.1.8.125262.1.8.2272.22.2.1282.2.22.2.2.12930288#48312.2.2.232586#2302.2.2.32.2.2.4332.2.2.52.2.32.2.3.1342.2.3.2352.2.3.3362.2.3.42.2.42.2.4.12.2.4.2372.2.4.3382.2.4.42.2.4.5392.2.4.640157#24412.2.52.2.5.1422.2.5.243462#3452.2.5.32.2.5.42.2.5.4.144452.2.5.4.246307#472.2.5.4.32.2.5.4.412#2347396#472.2.62.2.6.1482.2.6.2492.2.6.32.2.75033.1505152523#3863.253595#365543.33.3.15556355#3933.3.25758499#7273.3.33.3.3.159603.3.3.2613.3.3.362581#3473.4633.4.13.4.1.164585#246653.4.1.2585#29666673.4.1.36869324#2743.4.1.470586#31671581#4253.4.1.572562#2983.4.1.673386#16974316#1963.4.23.4.2.1260#137753.4.2.276495#2403.4.37778393#34079546#19880813.5823.5.183415#3773.5.284853.5.38687528#39088586#531899091586#1629249293586#3944.19495964.29798991001014.31021031041054.41061074.4.1108109331#4681101114.4.21124.4.31131144.4.41154.4.51161174.4.61184.51191204.6AbkürzungsverzeichnisLiteraturPublikationslisteDanksagungErklärungLebenslaufdeInhaltsverzeichnisHilfe Literatur Ahmad M and Cashmore AR (1993) HY4 gene of A. thaliana encodes a protein with characteristics of a blue-light photoreceptor. Nature 366: 162-166 Ahmad M, Lin C, Cashmore AR (1995) Mutations throughout an Arabidopsis blue-light photoreceptor impair blue-light-responsive anthocyanin accumulation and inhibition of hypocotyl elongation. Plant J. 8: 653-658 Ahmad M, Jarillo JA, Smirnova O, Cashmore AR (1998) The CRY1 blue light receptor of Arabidopsis interacts with phytochrome A in vitro. Mol. Cell 1: 939-948 Anderson SL and McIntosh L (1991) Light-activated heterotrophic growth of the cyanobacterium Synechocystis sp. Strain PCC 6803: a blue-light-requiring process. J. Bacteriol. 173: 2761-2767 Arvind L and Ponting CP (1997) The GAF domain: an evolutionary link between diverse phototransducing proteins. Trends Biochem. Sci. 22: 458-459 Beatson SA, Whitchurch CB, Sargent JL, Levesque RC, Mattick JS (2002) Differential regulation of twitching motility and elastase production by Vfr in Pseudomonas aeruginosa. J. Bacteriol. 184: 3605-3613 Beckmann M and Hegemann P (1991) In vitro identification of rhodopsin in the green alga Chlamydomonas. Biochemistry 30: 3692-3697 Bhaya D, Watanabe N, Ogawa T, Grossman AR (1999) The role of an alternative sigma factor in motility and pilus formation in the cyanobacterium Synechocystis sp. strain PCC6803. Proc. Natl. Acad. Sci. USA 96: 3188-3193 Bhaya D, Bianco NR, Bryant D, Grossman AR (2000) Type IV pilus biogenesis and motility in the cyanobacterium Synechocystis sp. PCC6803. Mol. Microbiol. 37: 941-951 Bhaya D, Takahashi A, Grossman AR (2001a) Light regulation of type IV-dependent motility by chemosensor-like elements in Synechocystis sp. strain PCC6803. Proc. Natl. Acad. Sci. USA 98: 7540-7545 Bhaya D, Takahashi A, Shahi P, Grossman AR (2001b) Novel motility mutants of Synechocystis strain PCC 6803 generated by in vitro transposon mutagenesis. J. Bacteriol. 183: 6140-6143 Bhaya D (2004) Light matters: phototaxis and signal transduction in unicellular cyanobacteria. Mol. Micriobiol. 53: 745-754 Bieszke JA, Braun EL, Bean LE, Kang S, Natvig DO, Borkovich KA (1999) The nop-1 gene of Neorospora crassa encodes a seven transmembrane helix retinal-binding protein homologous to archael rhodopsins. Proc. Natl. Acad. Sci. USA 96: 8034-8039 Borthwick HA, Hendricks SB, Parker MW, Toole VK (1952) A reversible photoreaction controlling seed germination. Proc. Natl. Acad. Sci. USA 38: 662-666 Bouly JP, Giovani B, Djamei, Mueller M, Zeugner A, Dudkin EA, Batschauer A, Ahmad M (2003) Novel ATP-binding and autophosphorylation activity assiated with Arabidopsis and human cryptochrome-1. Eur. J. Biochem. 270: 2921-2928 Braatsch S and Klug G (2004) Blue light perception in bacteria. Photosynth. Res. 79: 45-57 Briggs WR and Christie JM (2002) Phototropins 1 and 2: versatile plant blue-light receptors. Trends Plant Sci. 7: 204-210 Brudler R, Hitomi K, Daiyasu H et al. (2003) Identification of a new cryptochrome class: structure, function, and evolution. Mol. Cell 11: 59-67 Butler WL, Norris KH, Siegelman HW, Hendricks SB (1959) Detection, assay, and prelimnary purification of the pigment controlling photoresponsive development of plants. Proc. Natl. Acad. Sci. USA 45: 1703-1708 Campbell D, Hurry V, Clarke AK, Gustafsson P, Öquist G (1998) Chlorophyll fluorescence analysis of cyanobacterial photosynthesis and acclimation. Microbiol. Mol. Biol. Rev. 62: 667-683 Cantón F and Quail PH (1999) Both phyA and phyB mediate light-imposed repression of PHYA gene expression in Arabidopsis. Plant Physiol. 121: 1207-1215 Casal JJ, Davis SJ, Kirchenbauer D, Viczian A, Yanovsky MJ, Clough RC, Kircher S, Jordan-Beebe ET, Schäfer E, Nagy F, Vierstra RD (2002) The serine-rich N-terminal domain of oat phytochrome a helps regulate light responses and subnuclear localization of the photoreceptor. Plant Physiology 129: 1127-1137 Cashmore AR, Jarillo JA, Wu YJ, Liu D (1999) Cryptochromes: Blue light receptors for plants and animals. Science 284: 760-765 Choi G, Yi H, Lee J, Kwon YK, Soh MS, Shin B, Luka Z, Hahn TR, Song PS (1999) Phytochrome signalling is mediated through nucleoside diphosphate kinase 2. Nature 401: 610-613 Choi JS, Chung YH, Moon YJ, Kim C, Watanabe M, Song PS, Joe CO, Bogorad L, Park YM (1999) Photomovement of gliding cyanobacterium Synechocystis sp. PCC 6803. Photochem. Photobiol. 70: 95-102 Choi JS, Ahn MC, Chung YH, Kwon O, Suh KH, Park YM (2003) Light-induced dephosphorylation of a 65-kDa protein in the cyanobacterium Synechocystis sp. PCC6803. J. Plant Physiol. 160: 1259-1261 Clack T, Mathews S, Sharrock RA (1994) The phytochrome apoprotein family in Arabidopsis is encoded by five genes: the sequences and expression of PHYD and PHYE. Plant Mol. Biol. 25: 413-427 Colón-Carmona A, Chen DL, Yeh KC, Abel S (2000) Aux/IAA proteins are phosphorylated by phytochrome in vitro. Plant Physiol. 124: 1728-1738 Crosson S, Rajagopal S, Moffat K (2003) The LOV domain family: Photoresponsive signaling modules coupled to diverse output domains. Biochemistry 42: 2-10 Datta N, Hedges RW, Shaw EJ, Sykes RB, Richmond MH (1971) Properties of an R Factor from Pseudomonas aeruginosa. J. Bacteriol. 108: 1244-1249 Davis SJ, Vener AV, Vierstra RD (1999) Bacteriophytochromes: phytochrome-like photoreceptors from nonphotosynthetic eubacteria. Science 286: 2517-2520 Elich TD and Chory J (1997) Biochemical Characterization of Arabidopsis wild-type and mutant phytochrome B holoproteins. The Plant Cell 9: 2271-2280 Ermakova SY, Elanskaya IV, Kallies KU, Weihe A, Börner T, Shestakov SV (1993) Cloning and sequencing of mutant psbB genes of the cyanobacterium Synechocystis PCC 6803. Photosynth. Res. 37: 139-146 Fankhauser C, Yeh KC, Lagarias JC, Zhang H, Elich TD, Chory J (1999) PKS1, a substrate phosphorylated by phytochrome that modulates light signalling in Arabidopsis. Science 284: 1539-1541 Fankhauser C (2001) The phytochromes, a family of red/far-red absorbing photoreceptors. J. Biol. Chem. 276: 11453-11456 Fankhauser C and Staiger D (2002) Photoreceptors in Arabidopsis thaliana: light perception, signal transduction and entrainment of endogenous clock. Planta 216: 1-16 Foerstendorf H, Mummert E, Schäfer E, Scheer H, Siebert F (1996) Fourier-transform infrared spectroscopy of phytochrome: difference spectra of the intermediates of the photoreactions. Biochemistry 35: 10793-10799 Folta KM (2004) Green light stimulates early stem elongation, antagonizing light-mediated growth inhibition. Plant Physiol. 135: 1407-1416 Franche C and Damerval T (1988) Tests on nif probes and DNA hybridizations. In Packer L and Glazer AN (eds)

Methods Enzymol.,

vol. 167, Academic Press, Inc., USA, 803-808 Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC (2001) Functional genomic analysis of the HY2 Family of ferredoxin-dependent bilin reductases from oxygenic photosynthesic organisms. The Plant Cell 13: 965-978 Frohnmeyer H and Staiger D (2003) Ultraviolet-B radiation-mediated responses in plants. Balancing damage and protection. Plant Physiol. 133: 1420-1428 Fujita Y (1997) A study on the dynamic features of photosystem stochiometry: Accomplishments and problems for future studies. Photosynth. Res. 53: 83-93 Furuya M (1993) Phytochromes: their molecular species, gene family and functions. Annu. Rev. Plant Physiol. Plant Mol. Biol. 44: 617-645 Galperin MY, Nikolskaya AN, Koonin EV (2001) Novel domains of the prokaryotic two-component signal transduction systems. FEMS Microbiol. Lett. 203: 11-21 García-Domínguez M, Muro-Pastor MI, Reyes JC, Florencio FJ (2000) Light-dependent regulation of cyanobacterial phytochrome expression. J. Bacteriol. 182: 38-44 Garriga P and Manyosa J (2002) The eye photoreceptor protein rhodopsin. Structural implications for retinal disease. FEBS Lett. 528: 17-22 Giraud E, Fardoux J, Fourrier N, Hannibal L, Genty B, Bouyer P, Dreyfus B Vermeglio A (2002) Bacteriophytochrome controls photosystem synthesis in anoxygenic bacteria. Nature 417: 202-205 Giraud E, Zappa S, Jaubert M, Hannibal L, Fardoux J, Ariano JM, Boyer P, Genty B, Pignol D, Vermeglio A (2004) Bacteriophytochrome and regulation of the synthesis of the photosynthetic apparatus in Rhodopseudomonas palustris: pitfalls of using labratory strains. Photochem. Photobiol. Sci. 3: 587-591 Gomelsky M and Kaplan S (1998) AppA, a redox reulator of photosystem formation in Rhodobacter sphaeroides 2.4.1, is a flavoprotein. J. Biol. Chem. 273: 35319-35325 Gomelsky M and Klug G (2002) BLUF: a novel FAD-binding domain involved in sensory transduction in microorgansims. Trends Biochem.Sci. 27: 497-500 Grossman AR, Schaefer MR, Chiang GG, Collier JL (1993) The phycobilisome, a light-harvesting complex responsive to enviromental conditions. Microbiol. Rev. 57: 725-749 Häder DP (1979) Photomovement. In Haupt W and Feinleib M (eds) Physiology of movements.

Encyclopedia of Plant Physiology

, vol. 7, Springer Verlag Berlin, 268-309 Hansen U, Fiedler B, Rank B (2002) Variation of pigment composition and antioxidative systems along the canopy light gradient in a mixed beech/oak forest: a comparative study on deciduous tree species differing in shade tolerance. Trees 16: 354-364 Hauser BA, Cordonnier-Pratt MM, Daniel-Vedele F, Pratt LH (1995) The phytochrome gene family in tomato includes a novel subfamily. Plant Mol. Biol. 29: 1143-1155 Hecht GB and Newton A (1995) Identification of a novel response regulator required for the swarmer-to-stalked-cell transition in Caulobacter crescentus. J. Bacteriol. 177: 6223-6229 Hendricks SB and Borthwick HA (1967) The function of phytochrome in regulation of plant growth. Proc. Natl. Acad. Sci. USA 58: 2125-2130 Hitomi K, Okamoto K, Daiyasu H, Miyashita H, Iwai S, Toh H, Ishiura M, Todo T (2000) Bacterial cryptochrome and photolyase: characterization of two photolyase-like genes of Synechocystis sp. PCC6803. Nucl. Acids Res. 28: 2353-2362 Hübschmann T, Börner T, Hartmann E, Lamparter T (2001a) Characterization of the Cph1 holo-phytochrome from Synechocystis sp. PCC 6803. Eur. J. Biochem. 268: 2055-2063 Hübschmann T, Jorissen HJ, Börner T, Gärtner W, Tandeau de Marsac N (2001b) Phosphorylation of proteins in the light-dependent signalling pathway of a filamentous cyanobacterium. Eur. J. Biochem. 268: 3383-2289 Hughes J and Lamparter T (1999) Prokaryotes and Phytochrome. The connection to chromophores and Signaling. Plant Physiol. 121: 1059-1068 Hughes J, Lamparter T, Mittmann F, Hartmann E, Gärtner W, Wilde A, Börner T (1997) A prokaryotic phytochrome. Nature 386: 663 Huq E and Quail PH (2002) PIF4, a phytochrome-interacting bHLH factor, functions as a negative regulator of phytochrome B signalling in Arabidopsis. EMBO J. 21: 2441-2450 Ikeuchi M and Tabata S (2001) Synechocystis sp. PCC6803 - a useful tool in the study of the genetics of cyanobacteria. Photosynth. Res. 70: 73-83 Iseki M, Matsunaga S, Murakami A, Ohno K, Shiga K, Yoshida K, Sugai M, Takahashi T, Hori T, Watanabe M (2002) A blue-light-activated adenylyl cyclase mediates photoavoidance in Euglena gracilis. Nature 415: 1047-1051 Jiang Z, Sweem LR, Rushing BG, Devanathan S, Tollin G, Bauer CE (1999) Bacterial photoreceptor with similarity to photoactive yellow protein and plant phytochromes. Science 285: 406-409 Jiang Z and Bauer CE (2001) Component of the Rhodospirillum centenum photosensory apparatus with structural and functional similarity to methyl-accepting chemotaxis protein chemoreceptors. J. Bacteriol. 183: 171-177 Jorissen HJMM, Quest B, Remberg A, Coursin T, Braslavsky SE, Schaffner K, Tandeau de Marsac N, Gärtner W (2002) Two independent, light-sensing two-component systems in a filamentous cyanobacterium. Eur. J. Biochem. 269: 2662-2671 Jung K-H, Trivedi VD, Spudich JL (2003) Demonstration of a sensory rhodopsin in eubacteria. Mol. Microbiol. 47: 1513-1522 Kamei A, Yuasa T, Orikawa K, Geng XX, Ikeuchi M (2001) A eukaryotic-type protein kinase, SpkA, is required for the normal motility of the unicellular cyanobacterium Synechocystis sp. strain PCC 6803. J. Bacteriol. 183: 1505-1510 Kamei A, Yoshihara S, Yuasa T, Geng X, Ikeuchi M (2003) Biochemical and functional characterization of a eukaryotic-type protein kinase, SpkB, in the cyanobacterium, Synechocystis sp. PCC6803. Curr. Microbiol. 46: 296-301 Kaneko T, Sato S, Kotani H, Tanaka A, Asamizu E, Nakamura Y et al. (1996) Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions. DNA Res. 3: 109-136 Karniol B and Vierstra RD (2003) The pair of bacteriophytochromes from Agrobacterium tumefaciens are histidine kinases with opposing photobiological properties. Proc. Natl. Acad. Sci. USA 100: 2807-2812 Kehoe DM and Grossman AR (1996) Similarity of a chromatic adaptation sensor to phytochrome and ethylene receptors. Science 273: 1409-1412 Kim JI, Kozhukh GV, Song PS (2002) Phytochrome-mediated signal transduction pathways in plants. Biochem. Biophys. Res. Commun. 298: 457-463 Kim YH, Park YM, Kim SJ, Park YI, Choi JS, Chung YH (2004) The role of Slr1443 in pilus biogenesis in Synechocystis sp. PCC 6803: involvement in post-translational modifications of pilins. Biochem. Biophys. Res. Commun. 315: 179-186 Kircher S, Gil P, Kozma-Bognar L, Fejes E, Speth V, Husselstein-Muller T, Bauer D, Adam E, Schäfer E, Nagy F (2002) Nucleocytoplasmic partitioning of the plant photoreceptors phytochrome A, B, C, D, and E is regulated differentially by light and exhibits a diurnal rhythm. The Plant Cell 14: 1541-1555 Kohchi T, Mukougawa K, Frankenberg N, Masuda M, Yokota A, Lagarias JC (2001) The Arabidopsis HY2 gene encodes phytochromobilin synthase, a ferredoxin-dependent biliverdin reductase. The Plant Cell 13: 425-436 Kondou Y, Nakazawa M, Higashi S, Watanabe M, Manabe K (2001) Equal-quantum action spectra indicate fluence-rate-selective action of multiple photoreceptors for photomovement of the thermophilic cyanobacterium Synechococcus elongatus. Photochem. Photobiol. 73: 90-95 Kondou Y, Mogami N, Hoshi F, Kutsuna S, Nakazawa M, Sakurai T, Matsui, Kaneko T, Tabata S, Tanaka I, Manabe K (2002) Bipolar localization of putative photoreceptor protein for phototaxis in thermophilic cyanobacterium Synechococcus elongatus. Plant Cell Physiol. 43: 1585-1588 Lagarias JC and Lagarias DM (1989) Self-assembly of synthetic phytochrome holoprotein in vitro. Proc. Natl. Acad. Sci. USA 86: 5778-5780 Lamparter T, Mittmann F, Gärtner W, Börner T, Hartmann E, Hughes J (1997) Characterization of recombinant phytochrome from the cyanobacterium Synechocystis. Proc. Natl. Acad. Sci. USA 94: 11792-11797 Lamparter T, Michael N, Mittmann F, Esteban B (2002) Phytochrome from Agrobacterium tumefaciens has unusual spectral properties and reveals an N-terminal chromophore attachment site. Proc. Natl. Acad. Sci. USA 99: 11628-11633 Lapko VN, Jiang XY, Smith DL, Song PS (1999) Mass spectroscopic characterization of oat phytochrome A: isoforms and posttranslational modifications. Protein Sci 8: 1-11 Lehmann M and Wöber G (1976) Accumulation, mobilization and turn-over of glycogen in the blue-green bacterium Anacystis nidulans. Arch. Microbiol. 111: 93-97 Lin C (2002) Blue light receptors and signal transduction. Plant Cell 14 Suppl.:S207-S225 Lin C and Shalitin D (2003) Cryptochrome structure and signal transduction. Annu. Rev. Plant Biol. 54: 469-496 Liscum E and Briggs WR (1995) Mutations in the NPH1 locus disrupt the perception of phototrophic stimuli. Plant Cell 7: 473-485 Liu XL, Covington MF, Fankhauser C, Chory J, Wagner DR (2001) ELF3 encodes a circadian clock-regulated nuclear protein that functions in an Arabidopsis PHYB signal transduction pathway. Plant Cell 13: 1293-1304 Malhotra K, Kim ST, Batschauer A, Dawut L, Sancar A (1995) Putative blue-light photoreceptors from Arabidopsis thaliana and Sinapis alba with high degree of sequence homology to DNA photolyase contain the two photolyase cofactors but lack DNA repair activity. Biochemistry 34: 6892-6899 Mas P, Devlin PF, Panda S, Kay SA (2000) Functional interaction of phytochrome B and cryptochrome 2. Nature 408: 207-211 Masuda S and Bauer CE (2002) AppA is a blue light photoreceptor that antirepresses photosynthesis gene expression in Rhodobacter sphaeroides. Cell 110: 613-623 Masuda S, Hasegawa K, Ishii A, Ono T (2004) Light-induced structural changes in a putative blue-light receptor with a novel FAD binding fold sensor of blue-light using FAD (BLUF); Slr1694 of Synechocystis sp. PCC 6803. Biochemistry 43: 5304-5313 Mathews S and Sharrock RA (1996) The phytochrome gene family in grasses (Poaceae): A phylogeny and evidence that grasses have a subset of the loci found in dicot angiosperms. Mol. Biol. Evol. 13: 1141-1150 McBride MJ (2001) Bacterial gliding motility: multiple mechanisms for cell movement over surfaces. Annu. Rev. Microbiol. 55: 49-75 Moa HB, Li GF, Li DH, Wu QY, Gong YD, Zhang XF, Zhao NM (2003) Effects of glycerol and high temperatures on structure and function of phycobilisomes in Synechocystis sp. PCC 6803. FEBS Lett. 553: 68-72 Montgomery BL and Lagarias JC (2002) Phytochrome ancestry: sensors of bilins and light. Trends Plant Sci. 7: 357-366 Moon YJ, Park YM, Chung YH, Choi JS (2004) Calcium is involved in photomovement of cyanobacterium Synechocystis sp. PCC 6803. Photochem. Photobiol. 79: 114-119 Myers J, Graham JR and Wang RT (1980) Light-harvesting in Anacystis nidulans studied in pigment mutants. Plant Physiol. 66: 1144-1149 Nagy F and Schäfer E (2002) Phytochromes control photomorphogenisis by differentially regulated, interacting signalling pathways in higher plants. Annu. Rev. Plant Biol. 53: 329-355 Ng WO and Pakrasi HB (2001) DNA photolyase homologs are the major UV resistance factors in the cyanobacterium Synechocystis sp. PCC 6803. Mol. Gen. Genet. 264: 924-930 Ng WO, Grossman AR, Bhaya D (2003) Multiple light inputs control phototaxis in Synechocystis sp. strain PCC 6803. J. Bacteriol. 185: 1599-1607 Ni M, Tepperman JM, Quail PH (1998) PIF3, a phytochrome-interacting factor necessary for normal photoinduced signal transduction, is a novel basic helix-loop-helix protein. Cell 95: 657-667 Niyogi KK (1999) Photoprotection revisited: genetic and molecular approaches. Annu. Rev. Plant Physiol. Plant Mol. Biol. 50: 333–59 Nozue K, Kanegae T, Imaizumi T, Fukuda S, Okamoto H, Yeh KC, Lagarias JC, Wada M (1998) A phytochrome from the fern Adiantum with features of the putative photoreceptor NPH1. Proc. Natl. Acad. Sci. USA 95: 15826-15830 Ntefidou M, Iseki M, Watanabe M, Lebert M, Haeder DP (2003) Photoactivated adenylyl cyclase controls phototaxis in the flagellate Euglena gracilis. Plant Physiol. 133: 1517-1521 Ochoa de Alda JAG, Ajlani G, Houmard J (2000) Synechocystis strain PCC 6803 cya2, a prokaryotic gene that encodes a guanylyl cyclase. J. Bacteriol. 182: 3839-3842 Ohmori M, Terauchi K, Okamoto S, Watanabe M (2002) Regulation of cAMP-mediated photosignaling by a phytochrome in the cyanobacterium Anabaena cylindrica. Photochem. Photobiol. 75: 675-679 Okajima K, Yoshihara S, Geng X, Katayama M, Ikeuchi M (2003) Structural analysis of a novel flavoprotein in Cyanobacteria. Plant Cell Physiol. 44: 162 (Suppl.) Okamoto S, Ikeuchi M, Ohmori M (1999) Experimental analysis of recently transposed insertion sequences in the cyanobacterium Synechocystis sp. PCC6803. DNA Res. 6: 265-273 Otto H, Lamparter T, Borucki B, Hughes J, Heyn MP (2003) Dimerization and inter-chromophore distance of Cph1 phytochrome from Synechocystis, as monitored by fluorescence homo and hetero energy transfer. Biochemistry 42: 5885-5895 Park CM, Kim JI, Yang SS, Kang JG, Kang JH, Shim JY, Chung YH, Park YM, Song PS (2000) A second photochromic bacteriophytochrome from Synechocystis sp. PCC 6803: Spectral analysis and down-regulation by light. Biochemistry 39: 10840-10847 Paul MJ and Pellny TK (2003) Carbon metabolite feedback regulation of leaf photosynthesis and development. J. Exp. Bot. 54: 539-547 Paul R, Weiser S, Amiot NC, Chan C, Schirmer T, Giese B, Jenal U (2004) Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain. Genes Dev. 18: 715-727 Pelroy RA, Kirk MR, Bassahm JA (1976) Photosystem II regulation of macromolecule synthesis in the blue-green alga Aphanocapsa 6714. J. Bacteriol. 128: 623-632 Quail PH (2002) Photosensory perception and signalling in plant cells: new paradigms? Curr. Opin. Cell Biol. 14: 180-188 Reed JW (1999) Phytochromes are Pr-ipatetic kinases. Curr. Opin. Plant Biol. 5: 393-397 Rippka R, Desrulles J, Waterbury JB, Herdman M, Stanier RY (1979) Genetic assignment, strain histories and properties of pure cultures of cyanobacteria. J. Gen. Microbiol. 11: 1-61 Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2 nd edition.

Cold Spring Harbor Laboratory,

Cold Spring Harbor, New York Sancar A (2003) Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors. Chem. Rev. 103: 2203-2237 Sanger F, Nickeln S, Coulsen AR (1977) DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74: 5463-5467 Schäfer E and Bowler C (2002) Phytochrome-mediated photoperception and signal transduction in higher plants. EMBO reports 3: 1042-1048 Schmitz O, Katayama M, Williams SB, Kondo T, Golden SS (2000) CikA, a bacteriophytochrome that resets the cyanobacterial circadian clock. Science 289: 765-768 Schneegurt MA, Sherman DM, Sherman LA (1997) Composition of the carbohydrate granules of the cyanobacterium, Cyanothece sp. strain ATCC 51142. Arch. Microbiol. 167: 89-98 Sengbusch P v, Bergmann R, Stader L, Eickmeier (1996) Botanik.

Elektronisches Buch

Shalitin D, Xuhong Y, Maymon M, Mockler T, Lin C (2003) Blue-light-dependent in vivo and in vitro phosphorylation of Arabidopsis cryptochrome 1. Plant Cell 15: 2421-2429 Shalitin D, Yang HY, Mockler TC, Maymon M, Guo HW, et al. (2002) Regulation of Arabidopsis cryptochrome 2 by blue-light-dependent phosphorylation. Nature 417: 763-767 Sharrock RA, and Quail PH (1989) Novel phytochrome sequences in Arabisdopsis thaliana: structure, evolution, and differential expression of plant regulatory photoreceptor family. Genes Dev. 3: 1745-1757 Shibata M, Ohkawa H, Kaneko T, Fukuzawa H, Tabata S, Kaplan A, Ogawa T (2001) Distinct constitutive and low-CO2-induced CO2 uptake systems in cyanobacteria: genes involved and their phylogenetic relationship with homologous genes in other organisms. Proc. Natl. Acad. Sci. USA 98: 11789-94 Shinomura T, Uchida K, Furuya M (2000) Elementary processes of photoperception by phytochrome A for high-irradiance response of hypocotyl elongation in Arabidopsis. Plant Physiol. 122: 147-156 Sineshchekov OA, Jung KH, Spudich JL (2002) Two rhodopsins mediate phototaxis to low- and high-intensity light in Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. USA 99: 8689-8694 Singh AK, McIntyre LM, Sherman LA (2003) Microarray analysis of the genome-wide response to iron deiciency and iron reconstition in the cyanobacterium Synechocystis sp. PCC 6803. Plant Physiol. 132: 1825-1839 Skerker JM and Berg HC (2001) Direct observation of extension and retraction of type IV pili. Proc. Natl. Acad. Sci. USA 98: 6901-6904 Smith H (2000) Phytochromes and light signal perception by plants - an emerging synthesis. Nature 407: 585-591 Spudich JL (1998) Variations on a molecular switch: transport and sensory signalling by archaeal rhodopsins. Mol. Microbiol. 28: 1051-1058 Stowe-Evans EL and Kehoe DM (2004) Signal transduction during light-quality acclimation in cyanobacteria: a model system for understanding phytochrome-response pathways in prokaryatos. Photochem. Photobiol. Sci. 3: 495-502 Sullivan JA and Deng XW (2003) From seed to seed: the role of photoreceptors in Arabidopsis development. Dev. Biol. 260: 289-297 Sweere U, Eichenberg K, Lohrmann J, Mira-Rodado V, Bäurle I, Kudla J, Nagy F, Schäfer E, Harter K (2001) Interaction of the response regulator ARR4 with phytochrome B in modulating red light signalling. Science 294: 1108-1111 Taylor BL and Zhulin IB (1999) PAS domains: internal sensors of oxygen, redox potential, and light. Microlbiol. Mol. Biol. Rev. 63: 479-506 Terauchi K and Ohmori M (1999) An adenylate cyclase, cya1, regulates cell motility in the cyanobacterium Synechocystis sp. PCC6803. Plant Cell Physiol. 40: 248-251 Terauchi K and Ohmori M (2004) Blue light stimulates cyanobacterial motility via a cAMP signal transduction system. Mol. Microbiol. 52: 303-309 Terauchi K, Montgomery BL, Grossman AR, Lagarias JC, Kehoe DM (2004) RcaE is complementary chromatic adaptation photoreceptor required for green and red light responsiveness. Mol. Microbiol. 51: 567-577 Tischler AD and Camilli A (2004) Cyclic diguanylate (c-di-GMP) regulates Vibrio cholerae biofilm formation. Mol. Microbiol. 53: 857-869 van der Horst MA and Hellingwerf KJ (2004) Photoreceptor proteins, "star actors of modern times": a review of the functional dynamics in the structure of representative members of six different photoreceptor families. Acc Chem Res. 37: 13-20 Vierstra RD and Davis SJ (2000) Bacteriophytochromes: new tools for understanding phytochrome signal transduction. Semin. Cell Dev. Biol. 11: 511-521 Wang H and Deng XW (2002) Phytochrome signaling mechanism. In Meyerowitz E und Somerville C (eds)

The Arabidopsis Book

, American Society of Plant Biologists, 1-30 Wang H, Ma L, Li J, Zhao H, Deng XW (2001) Direct interaction of Arabidopsis cryptochromes with COP1 in light control of development. Science 294: 154-158 Wilde A, Churin Y, Schubert H, Börner T (1997) Disruption of a Synechocystis sp. PCC 6803 gene with partial similarity to phytochrome genes alters growth under changing light qualities. FEBS Letters 406: 89-92 Wilde A, Fiedler B, Börner T (2002) The cyanobacterial phytochrome Cph2 inhibits phototaxis towards blue light. Mol. Microbiol. 44: 981-988 Wu SH and Lagarias JC (2000) Defining the bilin lyase domain: lessons from the extendend phytochrome superfamily. Biochemistry 39: 13487-13495 Yang HQ, Wu YJ, Tang RH, Liu D, Liu Y, Cashmore AR (2000) The C termini of Arabidopsis cryptochrome mediate a constitutive light response. Cell 103: 815-827 Yang C, Hua Q, Shimizu K (2002) Metabolic flux analysis in Synechocystis using isotope distribution from 13 C-labeled glucose. Metab. Eng. 4: 202-216 Yeh KC and Lagarias JC (1998) Eukaryotic phytochromes: light-regulated serine/threonine protein kinases with histidine kinase ancestry. Proc. Natl. Acad. Sci. USA 95: 13976-13981 Yeh KC, Wu SH, Murphy JT, Lagarias JC (1997) A cyanobacterial phytochrome two-component light sensory system. Science 277: 1505-1508 Yoshihara S, Suzuki F, Fujita H, Geng XX, Ikeuchi M (2000) Novel putative photoreceptor and regulatory genes required for the positive phototactic movement of the unicellular motile cyanobacterium Synechocystis sp. PCC 6803. Plant Cell Physiol. 41: 1299-1304 Yoshihara S, Geng XX, Okamoto S, Yura K, Murata T, Go M, Ohmori M, Ikeuchi M (2001) Mutantional analysis of genes involved in pilus structure, motility and transformation competency in the unicellular motile cyanobacterium Synechocystis sp. PCC 6803. Plant Cell Physiol. 42: 63-73 Yoshihara S, Geng X, Ikeuchi M (2002) PilG gene cluster and split pilL genes involved in pilus biogenesis, motility and genetic transformation in the cyanobacterium Synechocystis sp. PCC 6803. Plant Cell Physiol. 43: 513-521 Yoshihara S and Ikeuchi M (2004) Phototactic motility in the unicellular cyanobacterium Synechocystis sp. PCC 6803. Photochem. Photobiol. Sci. 3: 512-518 Yoshimura H, Yanagisawa S, Kanehisa M, Ohmori M (2002a) Screening for the target gene of cyanobacterial cAMP receptor protein SYCRP1. Mol. Microbiol. 43: 843-853 Yoshimura H, Yoshihara S, Okamoto S, Ikeuchi M, Ohmori M (2002b) A cAMP receptor protein, SYCRP1, is responsible for the cell motility of Synechocystis sp. PCC6803. Plant Cell Physiol. 43: 460-463 Zinchenko VV, Piven IV, Melnik VA, Shestakov SV (1999) Vectors for the complementation analysis of cyanobacterial mutants. Russian Journal of Genetics 35: 291-296