A. dest.

Aqua destillata

Abb.

Abbildung

ACD-A

Acid-Citrate-Dextrose-Anticoagulant

Ach

Acetylcholin

ADP

Adenosindiphosphat

AM

Acetoxymethyl

APS

Ammoniumpersulfat

AR

adrenerger Rezeptor

ATP

Adenosintriphosphat

AUC

area under the curve

BSA

bovines Serumalbumin

CD

cluster of differentiation

DCM

Dilatative Kardiomyopathie

DMSO

Dimethylsulfoxid

D-PBS

Dulbecco’s phosphate buffered saline

DTT

Dithiothreitol

Durchfl.

Durchfluss

E/ml

Einheit pro Milliliter

ECL

enhanced chemiluminescence

EDTA

Ethylendiamintetraessigsäure

EGTA

[Ethylen-bis-(oxyethylennitrilo)]-tetraessigsäure

ERK1/2

extracellular-signal regulated kinase 1/2

ET1

Endothelin-1

FACS

fluorescence activated cell sorting

FBS

fetal bovine serum

FCS

fetal calf serum

FITC

Fluoresceinisothiocyanat

FKS

fötales Kälberserum

FUDR

5’-Fluor-2’-desoxyuridin

gew. Tbz.

gewaschene Thrombozyten

H+L

schwere und leichte Kette

hCASMC

human coronary artery smooth muscle cells

hEGF

human epidermal growth factor

HEPES

N-[2-Hydroxyethyl]piperazin-N’-[2-ethansulfonsäure]

hFGF

human fibroblast growth factor

HLA

human leucocyte antigen

HPLC

high performance liquid chromatography

HSA

humanes Serumalbumin

5-HT

Serotonin

IE

internationale Einheiten

IgG

Immunglobulin G

IL-1β bzw. IL-6

Interleukin-1β bzw. -6

KF

Kulturflasche

Ko.

Kontrolle

LPS

Lipopolysaccharid

MAPK

mitogen activated protein kinase

MCLA

Methyl-Cypridina-Luciferin-Analog

2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-on-hydrochlorid

musc.

muscarinerg

MWCO

Molecular Weight Cut Off

NADPH

reduziertes Nikotinamid-adenin-dinukleotid-phosphat

n.s.

nicht signifikant

neon.

neonatal

NFATc1

nuclear factor of activated T-cells c1

NFκB

n uclear f actor that binds the κ light chain enhancer in B -cells

NKS

neonatales Kälberserum

PAGE

Polyacrylamid-Gelelektrophorese

PAR1

protease activated receptor 1

Pat.

Patient

PBMC

peripheral mononuclear cells

PBS

phosphate buffered saline

PE

Phycoerythrin

pERK1/2

phosphorylated extracellular-signal regulated kinase 1/2

PGE₁

Prostaglandin E₁

pH

potentia hydrogenii

PMA

Phorbol-12-myristat-13-acetat

PMSF

Phenylmethylsulfonylfluorid

PPP

platelet poor plasma

PRP

platelet rich plasma

Reg.

Regenerat

RLU

relative luminescence units

rpm

rounds per minute

RPMI

Roswell Park Memorial Institute

SDS

sodium dodecyl sulphate

SEM

standard error of the mean

SFLLRN

L-Serin — L-Phenylalanin — L-Leucin — L-Leucin — L-Arginin — L-Asparagin

SLE

Systemischer Lupus erythematodes

SmBM

smooth muscle cell basal medium

SmGM-2

smooth muscle cell growth medium-2

TBS

tris buffered saline

TBST

tris buffered saline-tween

TEMED

N, N, N’, N’-Tetramethylethylendiamin

TF

tissue factor

Thr.

Thrombin

TSH

thyroid stimulating hormone

TV

Trypsin-Versen (EDTA)

Vorink.

Vorinkubation

YFLLRN

L-Tyrosin — L-Phenylalanin — L-Leucin — L-Leucin — L-Arginin — L-Asparagin