The role of the N-terminal acetyltransferase NatA in transcriptional silencing in Saccharomyces cerevisiae Antje Geißenhöner 111.1231.2451.367293#30481.49456#20910111.512491#18213141.6151617475#2981819305#1792021485#1551.7222324251.826272282.12.1.12.1.229302.1.32.1.431322.1.52.1.62.22.2.1332.2.234352.2.3362.2.42.2.52.2.637383393.1369#210403.23.2.141428#334423.2.2433.2.344592#659453#48446436#274473.2.43.2.548209#773.2.649404#2683.2.750113#703.33.3.151492#2523.3.252396#214533.3.3410#216543.3.4254#1243.3.555348#1123.3.656534#1113.43.4.157363#1493.4.258251#2213.53.5.1593.5.260528#315613.5.362367#2184634.16465664.267505#3246869208#1584.370714.472 References73747576777879808182838485868788899091 Abbreviations92 Curriculum vitae93 Publications94 Acknowledgements9596enTable of contentsHelp Abbreviations

aa

amino acid

a.i.

arbitrary intensity

ACS

ARS consensus sequence

ARS

autonomous replication sequence

BAH

bromo-adjacent homology

bp

base pair

ChIP

Chromatin Immunoprecipitation

Co-IP

Co-Immunoprecipitation

Da

Dalton

Gal4AD

Gal4 activation domain

Gal4BD

Gal4 binding domain

HA

hemagglutinin A

HAT

histone acetyltransferase

HDAC

histone deacetylase

HM

homothallic mating (HML und HMR)

HML

homothallic mating left

HMR

homothallic mating right

HDAC

histone methyltransferase

IEF

isoelectric focusing

IgG

Immune globulin G

MALDI-TOF

matrix-assisted laser desorption/ionization time of flight

MAT

mating-type locus

NAT

N-terminal acetyltransferase

OD

optical density

ORC

origin recognition complex

ORF

open reading frame

PEV

position effect variegation

pI

isoelectric point

rpm

rounds per minute

RT

room temperature

SDS

sodium dodecyl sulfate

Sir

silent information regulator

TAP

tandem affinity purification

TPE

telomere position effect

ts

temperature sensitive

WT

wild-type