<?xml version="1.0" encoding="ISO-8859-1"?><cms:container xmlns:cms="http://edoc.hu-berlin.de/diml/module/cms"><cms:document><cms:meta><cms:entry id="front" part="front" ref="front" type="front"/><cms:entry type="title">Streptococcus pneumoniae induziert Apoptose in zerebralen Endothelzellen:</cms:entry><cms:entry type="title">Die Rolle bakterieller Toxine </cms:entry><cms:entry type="author">Annett  Halle</cms:entry><cms:entry id="chapter1" part="chapter1" ref="chapter1" type="chapter">1</cms:entry><cms:entry id="N1007B" part="chapter1" ref="N1007B" type="pagenumber">1</cms:entry><cms:entry id="N10080" part="chapter1" ref="N10080" type="section">1.1</cms:entry><cms:entry id="N10085" part="chapter1" ref="N10085" type="subsection">1.1.1</cms:entry><cms:entry id="N1009E" part="chapter1" ref="N1009E" type="pagenumber">2</cms:entry><cms:entry id="N100B9" part="chapter1" ref="N100B9" type="subsection">1.1.2</cms:entry><cms:entry id="N100BD" part="chapter1" ref="N100BD" type="pagenumber">3</cms:entry><cms:entry id="N100D0" part="chapter1" ref="N100D0" type="pagenumber">4</cms:entry><cms:entry id="N100D7" part="chapter1" ref="N100D7" type="section">1.2</cms:entry><cms:entry id="N100ED" part="chapter1" ref="N100ED" type="mm">513#349</cms:entry><cms:entry id="N100FC" part="chapter1" ref="N100FC" type="subsection">1.2.1</cms:entry><cms:entry id="N10100" part="chapter1" ref="N10100" type="pagenumber">5</cms:entry><cms:entry id="N10109" part="chapter1" ref="N10109" type="subsection">1.2.2</cms:entry><cms:entry id="N10112" part="chapter1" ref="N10112" type="subsection">1.2.3</cms:entry><cms:entry id="N10139" part="chapter1" ref="N10139" type="subsection">1.2.4</cms:entry><cms:entry id="N1013D" part="chapter1" ref="N1013D" type="pagenumber">6</cms:entry><cms:entry id="N10150" part="chapter1" ref="N10150" type="section">1.3</cms:entry><cms:entry id="N10155" part="chapter1" ref="N10155" type="subsection">1.3.1</cms:entry><cms:entry id="N1015F" part="chapter1" ref="N1015F" type="pagenumber">7</cms:entry><cms:entry id="N10166" part="chapter1" ref="N10166" type="mm">588#311</cms:entry><cms:entry id="N10176" part="chapter1" ref="N10176" type="subsection">1.3.2</cms:entry><cms:entry id="N1017D" part="chapter1" ref="N1017D" type="pagenumber">8</cms:entry><cms:entry id="N10190" part="chapter1" ref="N10190" type="pagenumber">9</cms:entry><cms:entry id="N101AC" part="chapter1" ref="N101AC" type="section">1.4</cms:entry><cms:entry id="N101B0" part="chapter1" ref="N101B0" type="pagenumber">10</cms:entry><cms:entry id="N101B5" part="chapter1" ref="N101B5" type="subsection">1.4.1</cms:entry><cms:entry id="N101C7" part="chapter1" ref="N101C7" type="subsection">1.4.2</cms:entry><cms:entry id="N101CE" part="chapter1" ref="N101CE" type="pagenumber">11</cms:entry><cms:entry id="N101DD" part="chapter1" ref="N101DD" type="subsection">1.4.3</cms:entry><cms:entry id="N101F3" part="chapter1" ref="N101F3" type="table"/><cms:entry id="N101FA" part="chapter1" ref="N101FA" type="pagenumber">12</cms:entry><cms:entry id="N10306" part="chapter1" ref="N10306" type="subsection">1.4.4</cms:entry><cms:entry id="N1030E" part="chapter1" ref="N1030E" type="block">1.4.4.1</cms:entry><cms:entry id="N1031B" part="chapter1" ref="N1031B" type="pagenumber">13</cms:entry><cms:entry id="OLE_LINK6" part="chapter1" ref="OLE_LINK6" type="link"/><cms:entry id="N1032D" part="chapter1" ref="N1032D" type="block">1.4.4.2</cms:entry><cms:entry id="N10337" part="chapter1" ref="N10337" type="pagenumber">14</cms:entry><cms:entry id="N1033B" part="chapter1" ref="N1033B" type="mm">409#367</cms:entry><cms:entry id="N1034C" part="chapter1" ref="N1034C" type="pagenumber">15</cms:entry><cms:entry id="N10353" part="chapter1" ref="N10353" type="subsection">1.4.5</cms:entry><cms:entry id="N1036E" part="chapter1" ref="N1036E" type="subsection">1.4.6</cms:entry><cms:entry id="N1037B" part="chapter1" ref="N1037B" type="pagenumber">16</cms:entry><cms:entry id="N10380" part="chapter1" ref="N10380" type="block">1.4.6.1</cms:entry><cms:entry id="N10393" part="chapter1" ref="N10393" type="pagenumber">17</cms:entry><cms:entry id="N103A0" part="chapter1" ref="N103A0" type="table"/><cms:entry id="N10471" part="chapter1" ref="N10471" type="mm">85#89</cms:entry><cms:entry id="N1047E" part="chapter1" ref="N1047E" type="mm">86#90</cms:entry><cms:entry id="N1048B" part="chapter1" ref="N1048B" type="mm">85#89</cms:entry><cms:entry id="N10499" part="chapter1" ref="N10499" type="section">1.5</cms:entry><cms:entry id="N1049D" part="chapter1" ref="N1049D" type="pagenumber">18</cms:entry><cms:entry id="chapter2" part="chapter2" ref="chapter2" type="chapter">2</cms:entry><cms:entry id="N104E4" part="chapter2" ref="N104E4" type="pagenumber">19</cms:entry><cms:entry id="N104E9" part="chapter2" ref="N104E9" type="section">2.1</cms:entry><cms:entry id="N10538" part="chapter2" ref="N10538" type="table"/><cms:entry id="N10595" part="chapter2" ref="N10595" type="pagenumber">20</cms:entry><cms:entry id="N105B4" part="chapter2" ref="N105B4" type="pagenumber">21</cms:entry><cms:entry id="N105CC" part="chapter2" ref="N105CC" type="section">2.2</cms:entry><cms:entry id="N105F4" part="chapter2" ref="N105F4" type="pagenumber">22</cms:entry><cms:entry id="N1061F" part="chapter2" ref="N1061F" type="table"/><cms:entry id="N108B7" part="chapter2" ref="N108B7" type="pagenumber">23</cms:entry><cms:entry id="N109D4" part="chapter2" ref="N109D4" type="section">2.3</cms:entry><cms:entry id="N109D8" part="chapter2" ref="N109D8" type="pagenumber">24</cms:entry><cms:entry id="N10A1B" part="chapter2" ref="N10A1B" type="pagenumber">25</cms:entry><cms:entry id="N10A1F" part="chapter2" ref="N10A1F" type="mm">505#230</cms:entry><cms:entry id="N10A32" part="chapter2" ref="N10A32" type="section">2.4</cms:entry><cms:entry id="N10A36" part="chapter2" ref="N10A36" type="pagenumber">26</cms:entry><cms:entry id="N10A78" part="chapter2" ref="N10A78" type="section">2.5</cms:entry><cms:entry id="N10A7C" part="chapter2" ref="N10A7C" type="pagenumber">27</cms:entry><cms:entry id="N10AA3" part="chapter2" ref="N10AA3" type="section">2.6</cms:entry><cms:entry id="N10AA7" part="chapter2" ref="N10AA7" type="pagenumber">28</cms:entry><cms:entry id="N10ADB" part="chapter2" ref="N10ADB" type="pagenumber">29</cms:entry><cms:entry id="N10AE1" part="chapter2" ref="N10AE1" type="section">2.7</cms:entry><cms:entry id="N10B03" part="chapter2" ref="N10B03" type="table"/><cms:entry id="N10BC9" part="chapter2" ref="N10BC9" type="pagenumber">30</cms:entry><cms:entry id="N10BCF" part="chapter2" ref="N10BCF" type="section">2.8</cms:entry><cms:entry id="N10C12" part="chapter2" ref="N10C12" type="pagenumber">31</cms:entry><cms:entry id="N10C36" part="chapter2" ref="N10C36" type="section">2.9</cms:entry><cms:entry id="N10C48" part="chapter2" ref="N10C48" type="section">2.10</cms:entry><cms:entry id="N10C4C" part="chapter2" ref="N10C4C" type="pagenumber">32</cms:entry><cms:entry id="N10C5E" part="chapter2" ref="N10C5E" type="section">2.11</cms:entry><cms:entry id="N10C67" part="chapter2" ref="N10C67" type="section">2.12</cms:entry><cms:entry id="N10C7D" part="chapter2" ref="N10C7D" type="table"/><cms:entry id="N10D57" part="chapter2" ref="N10D57" type="pagenumber">33</cms:entry><cms:entry id="N10D63" part="chapter2" ref="N10D63" type="section">2.13</cms:entry><cms:entry id="N10D67" part="chapter2" ref="N10D67" type="pagenumber">34</cms:entry><cms:entry id="N10DB0" part="chapter2" ref="N10DB0" type="table"/><cms:entry id="N10F11" part="chapter2" ref="N10F11" type="pagenumber">35</cms:entry><cms:entry id="N11040" part="chapter2" ref="N11040" type="pagenumber">36</cms:entry><cms:entry id="N1104A" part="chapter2" ref="N1104A" type="table"/><cms:entry id="N110F5" part="chapter2" ref="N110F5" type="table"/><cms:entry id="N11174" part="chapter2" ref="N11174" type="pagenumber">37</cms:entry><cms:entry id="N1117D" 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				Danksagung</cms:entry><cms:entry ref="N12BF2" type="pagenumber">94</cms:entry><cms:entry id="N12C0D" part="N12C0D" ref="N12C0D" type="appendix"/><cms:entry id="N12C0F" part="N12C0D" ref="N12C0F" type="p"/><cms:entry id="N12C11" part="N12C0D" ref="N12C11" type="pagenumber">95</cms:entry><cms:entry id="N12C16" part="N12C0D" ref="N12C16" type="p"/><cms:entry id="N12C1C" part="N12C0D" ref="N12C1C" type="p"/><cms:entry id="N12C22" part="N12C0D" ref="N12C22" type="p"/><cms:entry id="N12C28" part="N12C0D" ref="N12C28" type="p"/><cms:entry id="N12C2E" part="N12C0D" ref="N12C2E" type="p"/><cms:entry id="N12C34" part="N12C0D" ref="N12C34" type="p"/><cms:entry id="N12C3B" part="N12C3B" ref="N12C3B" type="vita">
				Lebenslauf</cms:entry><cms:entry id="N12C3F" part="N12C3B" ref="N12C3F" type="pagenumber">96</cms:entry><cms:entry id="N12C46" part="N12C3B" ref="N12C46" type="table"/><cms:entry id="N12DB0" part="N12DB0" ref="N12DB0" type="declaration">
				Eidesstattliche Erklärung</cms:entry><cms:entry id="N12DB4" part="N12DB0" ref="N12DB4" type="pagenumber">97</cms:entry><cms:entry part="N12BEE" type=":current"/><cms:entry type=":lang">de</cms:entry><cms:entry id=":contents" part="front" ref=":contents" type=":contents">Inhaltsverzeichnis</cms:entry><cms:entry type=":help"><url href="http://...">Hilfe</url></cms:entry></cms:meta><cms:content><acknowledgement id="N12BEE">
			<head>
				<pagenumber id="N12BF2" label="94" numbering="arabic" start="94"/>Danksagung</head>
			<p>Ich danke meinem Doktorvater Herrn Prof. Dr. Jörg Weber für die fachliche und persönliche Unterstützung sowie für die Möglichkeit, in der ebenso engagierten wie freundschaftlichen Atmosphäre der Arbeitsgruppe zu forschen und die Ergebnisse auf Fachkongressen zu präsentieren.</p>
			<p>Besonderen Dank schulde ich meiner Betreuerin Frau Dr. Dorette Freyer, deren methodische Anleitung, wissenschaftlicher Rat und Motivation eine unschätzbare Hilfe für mich waren.</p>
			<p>Ich danke allen Mitarbeiterinnen und Mitarbeitern der Experimentellen Neurologie, die mich bereitwillig und tatkräftig unterstützt haben, allen voran Renate Gusinda, Claudia Muselmann und Émilie Dagand. Sie haben durch viele Hilfestellungen und eine gute Arbeitsatmosphäre zum Gelingen dieser Arbeit beigetragen.</p>
			<p>Frau Dr. Daniela Bermpohl danke ich für die freundschaftliche Zusammenarbeit und zahlreiche fruchtbare Diskussionen.</p>
			<p>Ich danke den wissenschaftlichen Kooperationspartnern Herrn Prof. Dr. Ingo Bechmann vom Institut für Anatomie der Charité Berlin für die Hilfestellung bei den Elektronenmikroskopischen Aufnahmen sowie Frau Prof. Elaine Tuomanen vom Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, USA für die Überlassung der Pneumokokkenmutanten.</p>
			<p>Meinem Freund Gabor Petzold danke ich für die Korrektur des Manuskripts und seine liebevolle Unterstützung.</p>
			<p>Schließlich möchte ich meinen Eltern danken, deren materielle und ideelle Unterstützung die Entstehung dieser Arbeit möglich gemacht hat. Ihnen widme ich diese Arbeit.</p>
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