3. Ackerman AB, Schiff TA (1996): If small plaque (digitate) parapsoriasis is a cutaneous T-cell lymphoma, even an 'abortive' one, it must be mycosis fungoides. Arch Dermatol 132: 562

4. Alibert JLM (1806): Tableau du plan fonoide: Descrptióndes maladies de la peau observée a l´hospital St. Louis, et exposition des meilleures méthods suivies pour leur traitement. Paris, barios l´Ainé et files

5. Asadullah K et al. (1996 ): IL-7mRNA is not overexpressed in cutaneous t-cell lymphoma and is unlikely to be an autocrine growth factor in vivo. Arch Derm Res 289: 9-13

6. Asadullah K et al. (1996): Progression of mycosis fungoides is associated with increasing cutaneous expression of IL-10 mRNA. J Invest Dermatol 107: 833-37

7. Asadullah K et al. (1997): Granzyme a mRNA expression in mycosis fungoides progression. Blood 90: 3810-11

8. Asadullah K et al. (1997): Enhanced expression of t-cell activation and natural killer cell antigens indicates systemic anti-tumor response in early primary cutaneous t-cell lymphoma. J Invest Dermatol 108: 743-7

9. Bakels V et al. (1992): Frequency and prognostic significance of clonal T-cell receptor rearrangements in the peripheral blood of patients with MF. Archives in Dermatology 128: 1602-1607

10. Bergman R et al. (1998): Immunophenotyping and t cell receptor gamma Rearrangement analysis as an adjunct to the histophatologic diagnosis of mycosis fungoides. Journal of American Academy of Dermatology 39: 554-559

11. Berliner N et al. (1986): T cell receptor gene rearrangements define a monoclonal T cell proliferation in patients with T cell lymphocytosis and cytopenia. Blood 67: 914-8.

12. Beylot-Barry M et al. (2001): Evidence that an identical t cell clone in skin and peripheral blood lymphocytes is an independent prognostic factor in primary cutaneous t cell lymphoma. J Invest Dermatol 117: 920-926

13. Borst J et al. (1987): A t cell receptor γ /CD3 complex found on cloned functional lymphocytes. Nature 324: 268-70

14. Bottaro M (1994): Heteroduplex analysis of t cell receptor γ gene Rearrangements for diagnosis and monitoring of cutaneous lymphomas. Blood 83: 3271-78

15. Braun-Falco O. (1995): Dermatologie und Venerologie, Springer, Berlin, Heidelberg, New Yor k:1404-7

16. Breit TM et al. (1991): Limited combinatorial repertoire of γδ t cell receptors expressed by t-cell acute lymphoblastic leukemias. Leukemia 5: 116-24

17. Breit TM et al. (1992): Receptor diversity of human T-cell receptor γδ expressing cells. Progress in Histo- and Cytochemistry 26: 182 –193

18. Breit TM et al. (1994): Unravelling human t cell receptor junctional region sequences. Thymus 22: 177-199

19. Breit TM et al. (1995): Gene rearrangements in human T cells. Leukemia 9(5): 936

20. Breslauer KJ et al. (1986): Predicting DNA duplex stability from the base sequence. Proceedings of the National Academy of Science of the USA 83: 3746-3750

21. Brocq L (1902): Les parapsoriasis. Ann Dermatol Syphiligr (Paris) 3: 433

22. Burg G, Dummer R (1995): Small plaque (digitate) parapsoriasis is an 'abortive cutaneous T-cell lymphoma' and is not mycosis fungoides. Arch Dermatol 131: 336 -8

23. Campbell JJ et al. (1999): The chemokine receptor CCR4 in vacular recognition by cutaneous but not intestinal memory t cells. Nature 400: 776-80

24. Chiarion-Sileni V et al. (2002) : Phase II trial of interferon α 2a plus psoralen with ultraviolet light a in patients with cutaneous T-cell lymphoma. Cancer 95: 569-75

25. Clemmensen OJ et al. (1983): Lymphocyte function and chromosome aberrations in patients with early mycosis fungoides and parapsoriasis en plaques. J Invest Dermatol 81: 308 -13

26. Dalloul A et al. (1992): Interleukin-7 is a growth factor for Sézary lymphoma cells. J Clin Invest 90: 1054-60

27. Davis M, Bjorkman P (1988): T-cell antigen receptor genes and t-cell recognition. Nature 334: 395 – 402

28. Delfau-Larue MH et al. (1998): Prognostic significance of a polymerase chain reaction-detectable dominant T-lymphocyte clone in cutaneous lesions of patients with mycosis fungoides. Blood 92(9): 3376-80.

29. Delfau-Larue MH et al. (2000): Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma. Blood 96(9): 2987-2992

30. Dippel E et al. (1999): Clonal t cell receptor γ chain gene Rearrangement in advanced cutaneous t cell lymphoma: A critical evaluation. J Pathol 188: 146–154

31. Dippel E et al. (2001): T-cell clonality of undetermined significance. Blood 98(1): 247-48

32. Dobbeling U et al. (1998): Interleukin-15 is an autocrine/paracrine viability factor for cutaneous t cell lymphoma cells. Blood 92: 252-258

33. Dongen JJM, van et al. (1990): Development of human T-lymphocytes and their thymus dependency. Thymus 16: 207 – 234

34. Dongen JJM, van et al. (1998): Prognostic value of minimal residual disease in acute lymphoblastic leukemia in childhood. Lancet 352: 1731-38

35. Dongen JJM, van et al. (2003): Design and standardization of pcr primers and protocols for detection of clonal immunoglobulin and t cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 concerted action BMH4-CT98-3936. Leukemia 17: 2257-2317

36. Dummer R et al. (1992): Soluble interleukin-2 receptors inhibit interleukin 2-dependent proliferation and cytotoxicity: Explanation for diminished natural killer cell activity in cutaneous T-cell lymphomas in vivo? Journal of Investigative Dermatology 98: 50- 4

37. Eckert C et al. (2000) : Potential of LightCycler technology for quantification of minimal residual disease in childhood acute lymphoblastic leukemia. Leukemia 14: 316-23

38. Edelson R et al. (1987): Treatrment of cutaneous t cell lymphoma by extracorporeal photochmeotherapy. N Engl J Med 316: 297-303

39. Fischer TC et al. (2004). Genomic aberrations and survival in cutaneous t cell lymphoma: J Inves Dermatol 122: 579-86

40. Fleischmayer R et al. (1965): Parapsoriasis en plaques and mycosis fungoides. Dermatologica 131: 149-160

41. Frazer-Andrews EA et al. (2000): Detection of a peripheral t cell clone is an independent prognostic factor in mycosis fungoides. J Invest Dermatol 114: 117-121

42. Garatti SA et al. (1995): Bcl-1, bcl-2, p53, c-myc, and lyt-10 analysis in cutaneous lymphomas. Recent Results Cancer Research 139: 249-261

43. Gill JI et al. (1994): Immunoglobulin and t-cell receptor gene rearrangement. Hematol Oncol Clin North Am. 8(4): 751-70.

44. Greene TC et al. (1979): Mycosis fungoides: Epidemiologic observations. Cancer Treat Rep 63: 597 – 606

45. Greiner MH et al.: (1999): Advances in molecular hematopathology: T-cell receptor γ and bcl 2 genes. Am. J. Path.; 154: 7 – 9

46. Gutzmer R et al. (2001): Detection of clonal t cell receptor γ gene Rearrangements in cutaneous t cell lymphomas by LightCycler polymerase chain reaction. J Invest Dermatol 116: 926-932

47. Haeffner AC et al. (1995): Differentiation and clonality of lesional lymphocytes in small plaque parapsoriasis. Arch Dermatol 131: 321 -4

48. Hansen ER et al. (1996): Immunoregulatory events in the skin of patients with cutaneous t cell lymphoma. Arch. Dermatol 132: 554-61

49. Harmon CB et al. (1996): Detection of circulating t cells with CD4+/CD7- immunophenotype in benign and malignant lymphoproliferative dermatoses. Journal of American Academy of Dermatology 35: 404-410

50. Herrmann JJ et al. (1995): Treatment in mycosis fungoides with photochemotherapy (PUVA): Longterm follow-up. J Am Acad Dermatol 33: 234 -42

51. Hoppe RT et al. (1979): Electron-beam therapy for mycosis fungoides: The stanford experience. Cancer Treat Rep 69: 691- 700

52. Hu CH (1993): Parapsoriasis. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF: Dermatology in General Medicine (IE), in 2 vols. 4th ed. New York, NY, Mc Graw-Hill: 1124-28

53. Izban KF et al. (1998): Immunohistochemical Analysis of mycosis fungoides in parrafin-embedded tissue sections. Mod Pathol 11(10): 978-82

54. Jakob T et al. (1996) : Stage dependent expression of CD7, CD45R0, CD45RA and CD25 on CD4 positive peripheral blood t cell lymphocytes in cutaneous t cell lymphoma. Acta Dermatol Venero 76: 34-36

55. Kaltoft K et al (1994): Cytogenetic findings in in cell lines from cutaneous T-cell lymphoma. Dermatol Clinics 12: 295 – 304

56. Kanavaros P et al. (1994): Mycosis fungoides: expression of C-myc, p62, p63, bcl-2 and PCNA proteins and absence of association with Epstein-Barr virus. Pathologic Research Practice 190: 767-774

57. Karenko L et al. (1999): Notable losses at specific regions of chromosomes 10q and 13q in the Sézary Syndrome detected by comparative genomic hybridization. J Invest Dermatol 112. 392-5

58. Karenko L et al. (2003): Chromosomal abnormalities in relation to clinical disease in patients with cutaneous t-cell lymphoma: a 5 –year follow up study. Br J Dermatol. 148(1): 55-64

59. Kikuchi A et al. (1997): Absence of human t-lymphotropic virus type I in japanese patients with cutaneous t-cell lymphoma. Blood 89: 1529-32

60. Klemke CD et al. (2002) : Clonal t cell receptor γ -chain gene Rearrangement by PCR-based Gene-Scan analysis in the skin and blood of patients with parapsoriasis and early-stage mycosis fungoides. Journal of Pathology 197 : 348-54

61. Kneba M et al. (1995): Analysis of rearranged t cell receptor β -chain genes by polymerase chain reaction (PCR) DNA sequencing and automated high resolution PCR Fragment Analysis. Blood 96: 3930-37

62. Laetsch B et al. (2000): CD4 + /CD7- T Cell frequency and polymerase chain reaction-based clonality assay correlate with stage in cutaneous t cell lymphomas. Journal of Investigative Dermatology 114: 107-111.

63. Lambert WC, Everett MA (1981): The nosology of parapsoriasis. J Am Acad Dermatol 5: 373

64. Lazar AP et al. (1989): Parapsoriasis and mycosis fungoides: the Northwestern University experience, 1970 to 1985. J Am Acad Dermatol 21: 919

65. Lefranc MP et al. (2003): IMGT, the internation ImMunoGeneTics database. Nucleic Acids Res 31: 307-10

66. Lefranc MP et al. (2003): IMGT databases, web resources and tools for immunoglobulin and t cell receptor sequence analysis, Leukemia 17: 260-66

67. Lessin SR et al. (1991): Molecular diagnosis of cutaneous t cell lymphoma: Polymerase chain reaction amplification of t cell antigen receptor β -chain Rearrangements. Journal of Investigative Dermatology 96: 299-302

68. Lindae ML et al. (1988): Poikilodermatous mycosis fungoides and atrophic large-plaque parapsoriasis exhibit similar abnormalities of T-cell antigen expression. Arch Dermatol 124: 366

69. Lukowsky A et al. (1998): Detection of monoclonal t cells with TCR- γ -PCR in mycosis fungoides. Hautarzt 49(8): 641-45

70. Lukowsky A et al. (2000): Detection of expanded t cell clones in skin biopsy samples of pathients with lichen sclerosus et atrophicus by t cell receptor gamma polymerase chain reaction assays. J Invest Dermatol 115: 254- 259

71. Lukowsky A et al. (2002): A t-cell receptor gamma polymerase chain reaction assay using capillary electrophoresis for the diagnosis of cutaneous t-cell lymphomas. Diagn Mol Pathol 11(2): 59-66

72. Mielke V et al. (1994): Clonal disease in early cutaneous t-cell lymphoma. Dermatologic Clinics 12: 351 – 360

73. Morales MM et al. (2003): Viral infection, atopy and mycosis fungoides: a european multicentre case-control study. Eur J Cancer 39(4): 511-6

74. Muche JM et al. (2003): Peripheral blood t cell clonality in mycosis fungoides and nonlymphoma controls. Diagn Mol Pathol 12: 142 – 150

75. Muche JM (2000): Peripheral blood t cell clonality in mycosis fungoides- an independent prognostic marker? J Invest Dermatol 115(3): 504-5

76. Muche JM (2000): Treatment of cutaneous t cell lymphomas. Seminars in Cutaneous Medicine and Surgery 19(2): 142-148

77. Muche JM , Sterry W. (2002): Vaccination therapy for cutaneous t-cell lymphoma. Clin Exp Dermatol 27(7): 602- 607

78. Muche JM et al. (2004): Cellular coincidence of clonal t cell receptor rearrangments and complex clonal chromosomal aberrations – a hallmark of malignancy in cutaneous t cell lymphoma: J Invest Dermatol 122: 574 – 78

79. Muche JM.: PCR- und Elektrophoresetechniken zum Nachweis einer monoklonalen T-Zell-Vermehrung am Beispiel der Diagnostik der Mycosis fungoides , Dissertation: 48 ff

80. Muche JM et al. (1997): Demonstration of frequent occurence of clonal t cells in peripheral cutaneous t cell lymphoma. Blood 90: 1636

81. Nakao M et al. (2000): Rapid and reliable quantification of minimal residual disease in acute lymphoblastic leukemia using rearranged immunoglobulin and t cell receptor loci by LightCycler technology. Cancer Research 60: 3281-89

82. NCBI-Database: http:///

83. Peccoud J et al. (1998): Statistical estimations of PCR amplification rates, in Ferré F.: Gene Quantification, Birkhäuser Verlag, Boston: 111-128

84. Posnett DN et al. (1994): Clonal population of t cells in normal elderly humans: The t cell equivalent to “benign monoclonal gammapathy”. J Exp Med 179: 609-18

85. Powell EE et al. (1992): Measurement of mRNA by quantitative PCR with nonradioactive label. J Lipid Res 33: 609-14

86. Qiagen Inc. (1994): Handbook for the DIAGEN TGGE-system. Qiagen Inc., 9259 Etan Avenue, Chatsworth CA 91311, USA: 29

87. Rasmussen R (2001) : Quantification on the LightCycler. in Meuer S. et al.:Rapid cycle real-time PCR, Springer, Heidelberg: 21-35

88. Regauer S et al. (2002): Monoclonal t cell receptor gamma rearrangement in vulvar lichen sclerosus and squamous cell carcinoma. Am J Pathol 160: 1035 – 1045

89. Reischl U, Kochanowski B (1995): Quantitative PCR. Molecular Biotechnology 3: 55-71

90. Rich BE et al. (1993): Cutaneous lymphoproliferation and lymphomas on interleukin 7 transgenic mice. J Exp Med 177: 305-16

91. Roche Molecular Biochemicals (2000): LightCycler-System. Real-time PCR- as flexible as you are: 12-14

92. Rook AH et al. (1995): The immunopathogenesis of cutaneous t-cell lymphoma. Hematol Oncol Clin North Am 9: 997-1010

93. Rowden G et al. (1979): Target role of langerhans cells in mycosis fungoides: Transmission and immuno-electron microscopic studies. J Cutan Pathol 6(5): 364-82

94. Rowen L et al. (1996): The complete 685-kilobase DNA sequence of the human β t-cell receptor locus. Science 272: 1755-62

95. Rychlik W (1994): Oligo Primer Analysis Software Version 5.0 for Windows, Manual. National Biosciences, Inc. (NBI)

96. Samman PD (1972): The natural history of parapsoriasis en plaques (chronic superficial dermatitis) and prereticulotic poikiloderma. Br J Dermatol 87: 405 -11

97. Samman PD (1976): Parkes Weber Lecture 1976: Mycosis fungoides and other reticulosies. Clin Exp Dermatol 1: 197 – 214

98. Scheller U et al. (1998): Detection of clonal t-cell receptor gamma gene rearrangements in cells in cutaneous T cell lymphoma by polymerase chain reaction: comparison of mutation detection enhancement-polyacrylamide gel electrophoresis, temperature gradient gel electrophoresis and frag-ment analysis of sequencing gels. Electrophoresis 19: 653–658

99. Schneider BF et al. (1995): Familial occurence of cutaneous t-cell lymphoma: A case report of monozygotic twin sisters. Leukemia 9: 1979-81

100. Schwab R et al. (1997): Expanded CD4+ and CD8+ t-cell clones in elderly humans. The Journal of Immunology 158: 4493-99

101. Soydens H et al. (2000): Transient t cell receptor beta-chain variable region-specific expansions of CD4+ and CD8+ t cells during the early phase of pediatric human immunodeficiency virus infection: characterization of expanded cell populations by T cell receptor phenotyping. J Infect Dis 181:107-20.

102. Sterry W et al. (1989): CD4+ cutaneous t-cell lymphomas show the phenotype of helper/inducer t-cells (CD45RA-, Cdw29+). Journal of Investigative Dermatology 93: 413-416

103. Tycko B et al. (1989): Polymerase chain reaction amplification of rearranged antigen receptor genes using junction-specific oligonucleotides: Possible application for detection of minimal residual disease in Acute Lymphoblastic Leukemia. Cancer Cells 7: 47 – 52

104. Vega F et al. (2002): Clonal heterogeneity in mycosis fungoides and it´s relationship to clinical course. Blood 100(9): 3369-73

105. Velden VHJ van der et al. (2002): T cell receptor gamma gene Rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative pcr analysis. Leukemia 16: 1372-80

106. Volkenandt M et al. (1991): Development of highly specific and sensitive molecular probes for detection of cutaneous lymphoma. J Invest Dermatol 97: 137 – 140

107. Volkenandt M et al. (1993): Molecular detection of clone-specific DNA in hypopigmented lesions of a patient with early evolving Mycosis fungoides. Br Jour Dermatology 128: 423 – 428

108. Wack A et al. (1998): Age-realted modifications of the human alphabeta t cell repertoire due to different clonal expansion in the CD4+ and CD8+ subsets. Int Immunol 10: 1281-8

109. Wang Z et al. (1998): Determination of target copy number of quantitative standard used in PCR based diagnostic assays. In Ferré F.: Gene Quantification, Birkhäuser Verlag, Boston: 31-44

110. Weinstock MA et al. (1988): Mycosis fungoides in the United States. JAMA 60: 42-46

111. Wetmur JG (1991): DNA probes: applications of the principles of nucleic acid hybridization. Critical Revue in Biochemistry and Molecular Biology 26: 227-259

112. Willemze R et al. (1997): EORTC classification for primary cutaneous lymphomas: A proposal from the Cutaneous Lymphoma Study Group of the European Organization for Research and Treatment of Cancer. Blood 90(1): 354-71

113. Zackheim HS et al. (1990): Topical carmustine for cutaneous t cell lymphoma: A 15-year experience in 143 patients. J Am Acad Dermatol 22: 802

114. Zackheim HS et al. (1998): Treatment of cutaneous T cell lymphoma with retinoids. Dermatologic Therapy 7: 15 - 20

115. Zucker-Franklin D et al. (1994): The role of human t-cell lymphotropic viruses (HTLV I and II) in cutaneous T-cell lymphomas. Semin Derm 13: 160-65

© Die inhaltliche Zusammenstellung und Aufmachung dieser Publikation sowie die elektronische Verarbeitung sind urheberrechtlich geschützt. Jede Verwertung, die nicht ausdrücklich vom Urheberrechtsgesetz zugelassen ist, bedarf der vorherigen Zustimmung. Das gilt insbesondere für die Vervielfältigung, die Bearbeitung und Einspeicherung und Verarbeitung in elektronische Systeme.
DiML DTD Version 4.0Zertifizierter Dokumentenserver
der Humboldt-Universität zu Berlin
HTML-Version erstellt am: