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B. Curriculum Vitae

Name:	Zhyldyz Temirzhanovna Kabaeva
Date and place of birth:	21.10.1972, Djany-Alysh (Kyrgyzstan)
Marital status	single
Nationality:	Kyrgyz
Education
09.1979 - 06.1989	Certificate of Secondary School Education.
	Seconary School #7. Tokmok. Kyrgyzstan.
08.1989 - 06.1995	Medical Diploma of General Practitioner in Medicine. Kyrgyz State Medical Institute. Bishkek. Kyrgyzstan
09.1995 - 07.1997	Post-graduate clinical training course in Internal Medicine and Cardiology.
	National Centre of Cardiology and Internal Medicine. Bishkek. Kyrgyzstan.
10.1999 - 2002	MD-PhD student Thesis title: Genetic analysis in hypertrophic cardiomyopathy: missense mutations in the ventriuclar myosin regulatory light chain gene.
	Charité/Franz-Volhard-Klinik at Max-Delbrück-Centrum für molekülare Medizin Humboldt-Universität zu Berlin. Berlin. Germany.
	Supervisors: Prof. Dr. med. K. J. Osterziel and Dipl.-Ing. A. Perrot
Work experience
09.1997 - 03.1999	Medical Doctor at Cardiology Intensive Care Department
	National Centre of Cardiology and Internal Medicine.
	Bishkek. Kyrgyzstan.
Research experience
09.1997 - 06.1999	Research duties at Department of non-invasive diagnostic methods: Clinical and Echo evaluation of patients with caridomyopathies
	National Centre of Cardiology and Internal Medicine. Bishkek. Kyrgyzstan
10.1999 - 2002	Molecular genetics of cardiomyopathies: identification of causative genes and mutations in patients with Hypertrophic and Dilated Cardiomyopathies using PCR, single strand confromation polymorphism analysis, restriction fragment length polymorphism analysis, and direct automated DNA sequencing. Genotype-phenotype correlations.
	CardioGenetic Laboratory. Charitè/Franz-Volhrad-Klinik. Berlin. Germany
Awards and honours
06.1999 - 07.2000	Awarded the DAAD fellowship for research in molecular aspects of Familial Cardiomyopathies in Germany.

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Publications
Zhyldyz T Kabaeva, Andreas Perrot, Bastian Wolter, Rainer Dietz, Nuno Cardim, João Martins Correira, Hagen D. Schulte, Almaz A. Aldashev, Mirsaid M. Mirrakhimov , Karl Josef Osterziel. "Systematic analysis of the regulatory and essential light chain genes: genetic variants and mutations in hypertrophic cardiomyopathy“. European Journal of Human Genetics 2002; 10:741-748. N. Bit-Avragim, A. Perrot, Z. Kabaeva, D. Usupbaeva, R. Rudenko, B. Imanov, B. Isalieva, H. Schmidt-Traub, B. Hoffmann, M.M. Mirrakhimov, R. Geßner, K.J. Osterziel. "Novel mutations in the ß-myosin heavy chain gene in Kyrgyz families with hypertrophic cardiomyopathy". 66. Jahrestagung der Deutschen Gesellschaft für Kardiologie-Herz- und Kreislaufforschung, April 2000, Mannheim. A. Perrot, Z. Kabaeva, C. Geier, N. Bit-Avragim, R. Bergmann-Lips, E. von Hodenberg, P. Binner, T. Scheffold, K.J. Osterziel. "Die Mutation Arg58Gln für die Regulatorische Myosin Leichtkette ist assoziiert mit plötzlichen Herztod". 67. Jahrestagung der Deutschen Gesellschaft für Kardiologie-Herz- und Kreislaufforschung, April 2001, Mannheim. Z. Kabaeva, A. Perrot, C. Geier, M. Fitschen, N. Bit-Avragim, P. Binner, T. Scheffold, N Cardim, K.J. Osterziel. "The mutation Arg58Gln in the regulatory myosin light chain gene is associated with sudden cardiac death". XXII Annual Congress of the European Society of Cardiology, September 2001, Stockholm.

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