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4  Outlook

In the last years the development of target drugs for the treatment of cancers has dramatically increased, a progress that is likely to continue in the future. It is obvious that targeting molecular abnormalities has considerable advantage over unspecific systemic drugs such as the chemotherapy. They are more specific, thus less toxic, and more effective in the treatment of cancer [Stockwin, 03a]. It seems possible that targeted drugs will be used in association with existing medical, surgical, and radiotherapeutic therapies and will play an important role in the aim of curing cancer.

In the present work it was possible to identify TRPM8, as a perfect target for a specific prostate cancer therapy.

The focus in future experiments will be the development of specific drugs targeting TRPM8. It is hoped and expected that these therapeutics will lead to new and promising treatment forms of prostate cancer.


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