Borrmann, Steffen: Regulation der endothelialen NO-Synthase unter Hypoxie und proinflammatorischer Stimulation in pulmonal-arteriellen Endothelzellen

Literaturverzeichnis

Arnal, 1994 Arnal, J.F., Yamin, J., Dockery, S. & Harrison, D.G "Regulation of endothelial nitric oxide synthase mRNA, protein, and activity during cell growth " Am. J. Physiol. 267 1994 1381-8

Arnet, 1996 Arnet, U.A., McMillan. A., Dinerman, J.L., Ballermann, B. & Lowenstein, C.J. "Regulation of endothelial nitric-oxide synthase during hypoxia. 1996 " J. Biol. Chem. 271 1996 15069-73

Ausubel, 1994 Ausubel, I. & Frederick, M. "Current protocols in molecular biology " Frederick, M. New York John Wiley & Sons 1994 Unit: 10.2

Balligand, 1995 Balligand, J.L., Ungureanu-Longrois, D., Simmons, W.W., Kobzik, L., Lowenstein, C.J., Lamas, S., Kelly, R.A., Smith, T.W. & Michel, T. "Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1beta and IFN-gamma " Am. J. Physiol. 268 1995 1293-303

Bath, 1991 Bath, P.M.W., Hassel, D.G., Gladwin, A.-M., Palmer, R.M.J. & Martin, J.F. "Nitric oxide and prostacyclin: divergence of inhibitory effects on monocyte chemotaxis and adhesion to endothelium in vitro " Arterioscler. Thromb. 11 1991 254-60

Bradford, 1976 Bradford, M.M. "A rapid and sensitiv method for the quantification of microgram quantities of protein utilizing the principle of protein dry binding " Anal. Biochem. 72 1976 248-54

Channick , 1996 Channick, R.N. "Pulmonary Hypertension: Pathogenesis and Ethiology " Bordow, R.A. and Moser, K.M. Manual of Critical Problems in Pulmonary Medicine Boston Little, Brown and Company 1996 304-8

Chomczynski, 1987 Chomczynski, P. & Sacchi, N. "Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction " Anal. Biochem. 162 1987 156-9

Clementi, 1995 Clementi, E., Sciorati, C., Riccio, M., Miloso, M., Meldolesi, J. & Nistico, G. ". Nitric oxide action on growth factor-elicited signals. Phosphoinostide hydrolysis and Ca2+ responses are negatively modulated via a cGMP-dependent protein kinase I pathway " J. Biol. Chem. 270 1995 22277-82

De Caterina, 1995 De Caterina, R., Libby, P., Peng, H.-B., Thannikal, V.J., Rajavashisth, T.B., Gimbrone, M.A., Jr., Shin, W.S. & Liao, J.K. "Nitric oxide decreases cytokine-induced endothelial activation " J. Clin. Invest. 96 1995 60-8

Demiryurek, 1993 Demiryurek, A. T., Wadsworth, R.M., Kane, K.A. & Peacock, A.J. "The role of endothelium in hypoxic constriction of pulmonary artery rings " Am. Rev. Respir. Dis. 147 1993 283-90

Dinh-Xuan, 1991 Dinh-Xuan, A.T., Higenbottam, T.W., Clelland, C.A. et al. "Impairement of endothelium-dependent pulmonary-artery relaxation in chronic obstructiv lung disease " N. Engl. J. Med. 324 1991 1539-47

Feinberg, 1984 Feinberg, A.P. & Vogelstein, B. "A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity " Anal. Biochem. 137 1984 266-7

Furchgott, 1980 Furchgott, R.F. und Zawadzki, J.V. "The obligatory role of endothelial cells in the relaxation of arterial smooth muscle cells by acetylcholine " Nature 288 1980 373-6

Garg, 1989 Garg, U.C. & Hasid, A. "Nitric oxide generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells " J. Clin. Invest. 83 1989 1774-7

Giaid, 1995 Giaid, a. & Saleh, D. "Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension " N. Engl. J. Med. 333 1995 214-21

Graham, 1990 Graham, L.M., Vasil, A., Voelkel, N.F. & Stenmark, K.R. "Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia " Am. Rev. Respir. Dis. 142 1990 221-9

Graven, 1994 Graven, K.K., Troxler, R.F., Kornfeld, H., Panchenko, M.V. & Farber, H.W. "Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia " J. Biol. Chem. 269 1994 24446-53

Guo, 1995 Guo, F.H., De Raeve, H.R., Rice, T.W., Stuehr, D.J., Thunnissen, F.B. & Erzurum, S.C. "Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo " Proc. Natl. Acad. Sci. USA. 92 1995 7809-13

Hampl, 1995 Hampl, V., Cornfield, D.N., Cowan, N.J. & Archer, S.L. "Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells " Eur. Respir. J. 8 1995 515-22

Heath, 1993 Heath, D. "The pathology of pulmonary hypertension " Eur. Res. Rev. 3 1993 555-8

Hirata, 1988 Hirata, Y., Yoshimi, H., Takata, S., Watanabe, T.X., Kumagai, S., Nakajima, K. & Sakakibara, S. "Cellular mechanism of action by a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells " Biochem. Biophys. Res. Commun. 154 1988 868-75

Huang, 1995 Huang, P.L., Huang, Z., Mashimo, H., Bloch, K.D., Moskowitz, M.A., Bevan, J.A. & Fishman, M.C. "Hypertension in mice lacking the gene for endothelial nitric oxide synthase " Nature 377 1995 239-42

Jackson, 1990 Jackson, C. J., Garbett, P.K., Nissen, B. & Schrieber, L. "Binding of human endothelium to Ulex europaeus I-coated Dynabeads: application to the isolation of microvascular endothelium " J. Cell Sci. 112 1990 257-262

Janssens, 1992 Janssens, S. P., Shimouchi, A., Quertermous, T., Bloch, D. B. & Bloch, K. D. "Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase " J. Biol. Chem. 267 1992 14519-22

Kanno, 1994 Kanno, K., Hirata, Y., Imai, T., Iwashina, M. & Marumo, F. "Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells " Am. J. Physiol. 267 1994 2318-24

Karakurum, 1994 Karakurum, M., Shreeniwas, R., Chen, J., Pinsky, D., Yan, S.D., Anderson, M., Sunouchi, K., Major, J., Hamilton, T., Kuwabara, K. et al. "Hypoxic induction of interleukin-8 gene expression in human endothelial cells " J. Clin. Invest. 93 1994 1564-70

Karupiah, 1993 Karupiah, G., Xie, Q.W., Buller, R.M., Nathan, C., Duarte, C. & MacMicking, J.D. "Inhibition of viral replication by interferon-gamma-induced nitric oxide synthase " Science 261 1993 1445-8

Kelly, 1995 Kelly, S., Smith, T.W., & Michel, T. "Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1 beta and IFN-gamma " Am. J. Physiol. 268 1995 1293-303

Kourembanas, 1990 Kourembanas, S., Hannan, R.L. & Faller, D.V. "Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells " J Clin. Invest. 86 1990 670-4

Kourembanas, 1991 Kourembanas, S., Marsden, P.A., McQuillan, L.P. & Faller, D.V. "Hypoxia induces endothelin gene expression and secretion in cultured human endothelium " J. Clin. Invest. 88 1991 1054-7

Kourembanas, 1993 Kourembanas, S., McQuillan, L.P., Leung, G.K. & Faller, D.V. "Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia " J. Clin. Invest. 92 1993 99-104

Kourembanas, 1994 Kourembanas, S. & Bernfield, M. "Hypoxia and endothelial-smooth muscle cell interactions in the lung " Am J. Respir. Cell Mol. Biol. 11 1994 373-4

Lancaster, 1994 Lancaster, J.R., Jr. "Stimulation of the diffusion and reaction of endogenously produced nitric oxide " Proc. Natl. Acad. Sci. 91 1994 8137-41

Liao, 1995 Liao, J.K., Zulueta, J.J., Yu, F.-S., Peng, H.-B., Cote, C.G. & Hassoun, P.M. "Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen " J. Clin. Invest. 96 1995 2661-6

Liu, 1996 Liu, S.F., Adcock, I.M., Old, R.W., Barnes, P.J., & Evans, T.W. "Differential regulation of the constitutive and inducible nitric oxide synthase mRNA by lipopolysaccharide treatment in vivo in the rat " Crit. Care Med. 24 1996 1219-25

MacNaul, 1993 MacNaul, K.L. & Hutchinson, N.I. "Differential expression of iNOS and cNOS mRNA in human vascular smooth muscle cells and endothelial cells under normal and inflammatory conditions " Biochem. Biophys. Res. Comm. 196 1993 1330-4

Marletta, 1994 Marletta, A.M. "Nitric oxide synthase: aspects concerning structure and catalysis " Cell 78 1994 927-30

Marsden, 1993 Marsden, P.A., Heng, H.H.Q., Scherer, S.W., Stewart, R.J., Hall, A.V., Shi, X.-M., Tsui, L.-C. & Schappert, K.T. "Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene " J. Biol. Chem. 268 1993 17478-88

McQuillan, 1994 McQuillan, L.P., Leung, G.K., Marsden, P.A., Kostyk, S.K. & Kourembanas, S. "Hypoxia inhibits expression of eNOS via transcriptional mechanisms " Am. J. Physiol. 267 1994 1921-7

Michel, 1993 Michel, T., Li, G.K. & Busconi, L. "Phosphorylation and subcellular translocation of endothelial nitric oxide synthase " Proc. Natl. Acad. Sci. USA. 90 1993 6252-6

Morita, 1995 Morita, T., Perrella, M.A., Lee, M.E. & Kourembanas, S. "Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP " Proc. Natl. Acad. Sci. USA 92 1995 1475-9

Morita, 1995 Morita, T. & Kourembanas, S. "Endothelial cell expression of vasoconstrictors and growth factors is regulated by smooth muscle cell-derived carbon monoxide " J. Clin. Invest. 96 1995 2676-82

Nathan, 1992 Nathan, C. "Nitric oxide as a secretory product of mammalian cells " FASEB J. 6 1992 3051-64

Nathan, 1994 Nathan, C. & Xie, Q.-w. "Regulation and biosynthesis of nitric oxide " J. Biol. Chem. 269 1994 13725-8

Nathan, 1994 Nathan, C. & Xie, Q.-w. "Nitric oxide Synthases: Roles, Tolls and Controls " Cell 78 1994 915-8

O’Brien, 1984 O’Brien, R.F. & McMurty, I.F. "Endothelial cell (EC) supernatants contract bovine pulmonary artery (PA) rings " Am. Rev. Respir. Dis. 129 1984 337

Palmer, 1987 Palmer, R.M.J., Ferrige, A.G. und Moncada, S. "Nitric oxide accounts for the biolological activity of endothelium-derived relaxing factor " Nature 327 1987 524-6

Peiró, 1995 Peiró, C., Redondo, J., Rodríguez-Martínez, A., Angulo, J., Marín, J. & Sánchez-Ferrer, C.F. "Influence of endothelium on cultured vascular smooth muscle cell proliferation " Hypertension 25 1995 748-51

Pebke-Zaba, 1991 Pebke-Zaba, J., Higgenbottam, T.W., Dinh-Xuan, A.T., Stone, D. & Wallwork, J. "Inhaled nitric oxide as a cause of selectiv pulmonary vasodilatation in pulmonary hypertension " Lancet 338 1991 1173-4

Phelan, 1996 Phelan, M.W. & Faller, D.V. "Hypoxia decreases constitutive nitric oxide synthase transcript and protein in cultured endothelial cells " J. Cell. Physiol. 167 1996 469-76

Pietra, 1989 Pietra, G.G., Edwards, W.D., Kay, J.M., Rich, S., Kernis, J., Schloo, B., Ayres, S.M., Bergofsky, E.H., Brundage, B.H. & Detre, K.M. et al. "Histopathology of primary pulmonary hypertension. A qualitative and quantitative study of pulmonary blood vessels from 58 patients in the National Heart, Lung, and Blood Institute, Primary Pulmonary Hypertension Registry " Circulation 80 1989 1198-206

Pohl, 1991 Pohl, U., Herlan, K., Huang, a. Bassenge, E. "EDRF-mediated shear-induced dilation opposes myogenic vasoconstriction in small rabbit arteries " Am. J. Physiol. 261 1991 2016-23

Rabinovitch, 1979 Rabinovitch, M., Gamble, M., Nadas, A.S., Miettinen, O.S. und Reid, L. "Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features " Am. J. Physiol. 236 1979 818-27

Radomski, 1990 Radomski, M.W., Palmer, R.M.J. & Moncada, S. "An L-arginine/nitric oxide pathway present in human platelets regulates aggregation " Proc. Natl. Acad. Sci. USA 87 1990 5193-7

Radomski, 1993 Radomski, M.W., Vallance, P., Whitley, G., Foxwell, N. & Moncada, S. ". Plateled adhesion to human vascular endothelium is modulated by constitutive and cytokine induced nitric oxide " Cardiovasc. Res. 27 1993 1380-2

Ravichandran, 1995 Ravichandran, L.V., Johns, R.A. & Rengasamy, A. ". Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide " Am. J. Physiol. 268 1995 2216-23

Rengasamy, 1996 Rengasamy, A. & Johns, R.A. ". Determination for oxygen of nitric oxide synthase isoforms " J. Pharmacol. Exp. Ther. 276 1996 30-3

Roberts, 1992 Roberts, J.D., Polaner, D.M., Lang, P. & Zapol. W.M. ". Inhaled nitric oxid in persistent pulmonary hypertension of the newborn " Lancet 340 1992 818-9

Robinson, 1994 Robinson, L.J., Weremowicz, W., Morton, C.C. & Michel, T. ". Effects of candidate autocrine and paracrine mediators on growth responses in isolated rat arteries " Genomics 19 1994 350-7

Rosenkranz-Weiss, 1994 Rosenkranz-Weiss, P., Sessa, W.C., Milstien, S., Kaufman, S., Watson, C.A. & Pober, J.S. "Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells " J. Clin. Invest. 93 1994 2236-43

Schappert, 1993 Schappert, K.T. "Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene " J. Biol. Chem. 268 1993 17478-88

Schiffers, 1994 Schiffers, P.M., Fazzi, G.E., van Ingen Schenau, D. & De Mey, J.G. ". Effects of candidate autocrine and paracrine mediators on growth responses in isolated rat arteries " Arterioscler. Thromb. 14 1994 420-6

Schmidt, 1994 Schmidt, H.H.H.W. und Walter, U. "NO at work. " Cell 78 1994 919-25

Sekido, 1993 Sekido, N., Mukaida, N., Harada, A., Nakanishi, I., Watanabe, Y. & Matsushima, K. "Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8 " Nature 365 1993 654-7

Shaul, 1995 Shaul, P.W., North, A.J., Brannon, T.S., Ujiie, K., Wells, L.B., Nisen, P.A., Lowenstein, P.J., Snyder, S.H. & Star, R.A. "Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung " Am. J. Respir. Cell Mol. Biol. 13 1995 167-74

Shweiki, 1992 Shweiki, D., Itin, A., Soffer, D., & Keshet, E. "Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis " Nature 359 1992 843-5

Sneddon, 1988 Sneddon, J.M. & Vane, J.R. "Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells " Proc. Natl. Acad. Sci. USA 85 1988 2500-4

Spink, 1995 Spink, J., Cohen, J. & Evans, T.J. "The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase. Activation by nuclear factor-kappa B " J. Biol. Chem. 270 1995 29541-7

Stamler, 1994 Stamler, J.S. "Redox signaling: Nitrosylation and related target interactions of nitric oxide " Cell 78 1994 931-6

Steinberg, 1994 Steinberg, K.P., Milberg, J.A., Martin,T.R., Maunder, R.J, Cockrill, B.A. & Hudson, L.D. "Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome " Am. J. Respir. Crit. Care Med. 150 1994 113-22

Stenger, 1994 Stenger, S., Thuring, H., Rollinghoff, M. & Bogdan, C. "Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major " J. Exp. Med. 180 1994 783-93

Stenmark, 1994 Stenmark, K.R., Durmowicz, A.G., Roby, J.D., Mecham, R.P. & Parks, W.C. "Persistence of the fetal pattern of tropoelastin gene expression in severe neonatal bovine pulmonary hypertension " J. Clin. Invest. 93 1994 1234-42

Stewart, 1991 Stewart, D.J., Levy, R.D., Cernacek, P. & Langleben, D. "Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? " Ann. Int. Med. 114 1991 464-9

Su, 1995 Su, Y. & Block, E.R. "Hypoxia inhibits L-arginine synthesis from L-citrulline in porcine pulmonary artery endothelial cells " Am. J. Physiol. 269 1995 581-7

Terashima, 1994 Terashima, T., Kanazawa, M., Sayama, K., Ishizaka, A., Urano, T., Sakamaki, F., Nakamura, H., Waki, Y., Tasaka, S. "Granulocyte colony-stimulating factor exacerbates acute lung injury induced by intratracheal endotoxin in guinea pigs " Am. J. Respir. Crit. Care Med. 149 1994 1295-303

Uematsu, 1995 Uematsu, M., Ohara, Y., Navas, J.P., Nishida, K., Murphy, T.J., Alexander, R.W., Nerem, R.M. & Harrison, D.G. "Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress " Am. J. Physiol. 269 1995 1371-8

Venema, 1994 Venema, R.C., Nishida, K., Alexander, R.W., Harrison, D.G., Murphy, T.J. Organization of the bovine gene encoding the endothelial nitric oxide synthase" " Biochim. Biophys. Acta 1218 1994 413-20

Wagner, 1984 Wagner, D.D. & Marder, V.J. "Biosynthesis of von Willebrand protein by human endothelial cells: processing steps and their intracellular localization " J. Cell. Biol. 99 1984 2123-30

Weitzberg, 1993 Weitzberg, E., Rudehill, A. & Lundberg, J.M. "Nitric oxide inhalation attenuates pulmonary hypertension and improves gas exchanges in endotoxin shock " Eur. J. Pharmacol. 233 1993 85-94

Yanagisawa, 1988 Yanagisawa, M., Kurihara, H., Kimura, S., Tomobe, Y., Kobayashi, M., Mitsui, Y., Yazaka, Y., Goto, K. & Masaki, T. "A novel potent vasoconstrictor peptide produced by vascular endothelial cells " Nature 332 1988 411-5

Yoshizumi, 1990 Yoshizumi, M., Kurihara, H., Morita, T., Yamashita, T., Oh-Hashi, Y., Sugiyama, T., Takaku, F.,Yanagisawa, M., Masaki, T. & Yazaki, Y. "Interleukin 1 increases the production of endothelin-1 by cultured endothelial cells " Biochem. Biophys. Res. Commun. 166 1990 324-9

Yoshizumi, 1993 Yoshizumi, M., Perrella, M.A., Burnett, J.C., Jr. & Lee, M.E. "Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life " Circ. Res. 73 1993 205-9

Yue, 1994 Yue, T.L., Wang, X., Sung, C.P., Olson, B., McKenna, P.J., Gu, J.L. & Feuerstein, G.Z. "Interleukin-8. A mitogen and chemoattractant for vascular smooth muscle cells " Circ. Res. 75 1994 1-7


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