CITED LITTERATURE

Adey, N. B., Mataragnon, A. H., Rider, J. E., Carter, J. M., and Kay, B. K (1995). Characterization of phage that bind plastic from phage-derived random peptide libraries. Gene 156: 27-31

Arend, W. P., Smith, M. F., Janson, R. W., Joslin, and F. G (1991 ). IL-1 receptor antagonist and IL-1b production in human monocytes are regulated differently. J. Immunol147:1530-1536

Balow, J. E (1991). Kidney disease in system lupus erythematosus. Rheumatol. Int. 11: 113

Barbas, C. F (1995). Synthetic human antibodies. Nat Med. 8: 837-839.

Barbas III, C. F., Kang, A. S., Lerner, R. A., and Benkovic, S. J (1991 ). Assembly of combinatorial antibody libraries on phage surfaces: The gene III site. Proc. Natl. Acad. Sci. U. S. A. 88: 7978-7982

Basta, M., and Dalakas, M. C (1994). High-dose intravenous immunoglobulin exerts its beneficial effect in patients with dermatomyositis by blocking endomysial deposition of activated complement fragments. J. Clin. Inv.94: 1729-1735

Basta, M., Fries, L. F., Frank, and M. M (1991). High-dose intravenous immunoglobulin inhibits in vitro uptake of C4 fragments onto sensitized erythrocytes. Blood 77: 376-380

Blasczyk, R., Westhoff, U., and Grossewilde, H (1993). Soluble CD4, CD8 and HLA molecules in commercial immunoglobulin preparations. Lancet 341: 789-790

Breitling, F., Dübel, S., Seehaus, T., Klewinghaus, I., and Litlle, M (1991). A surface expression vector for antibody screening. Gene. 104:147-153

Burton, D. R., and Barbas III, C. F (1994). Human antibodies from combinatorial libraries. Adv. Immunol. 57:191-280

Bussell, J., and Hilgartner, U. W (1986). Usage of intravenous gammaglobulins in the treatment of chronic idiopathic thrombocytopenic purpura. In ''Clinical use of Intravenous Immunoglobulins'' (A Morrell and U. E. Nydegger, Eds,), pp. 217-221, Academic Press, Orlando

Cairns, E., Kwong, P. C., Misener, V., Ip, P., Bell, D. A., Siminovitch, K. A ( 1989 ). Analysis of variable region genes encoding a human anti-DNA antibody of normal origin. Implications for the molecular basis of human autoimmune responses. J Immunol. 143 : 685-691 .

Cary, S. P., Lee, J., Wagenknecht, R., and Silverman, G. J ( 2000 ) . Characterization of superantigen-induced clonal deletion with a novel clan III-restricted avian monoclonal antibody: exploiting evolutionary distance to create antibodies specific for a conserved VH region surface. J. Immunol. 164. 4730-4741

Casali, P., and Notkins, A.L (1989). Probing the human B cell repertoire with EBV: Polyreactive antibodies and CD5+ B lymphocytes. Ann. Rev. Immunol 7: 513-535

Chang, C. N., Landolfi, N. F., and Queen, C (1991). Expression of antibody Fab domains on bacteriophage surfaces: Potential use for antibody selection. J. Immunol. 147 3610-3614

Clarkson, S. B., Bussel, J. B., Kimberly, R. P., Valinsky, J. E., Nachman, R. L., and Unkeless, J. C (1986). Treatment of refractory immune thrombocytopenic purpura with an anti-Fc gamma-receptor antibody. N. Engl. J. Med. 314: 1236-1239

Cold Spring Harbor Laboratory course on monoclonal antibodies from combinatorial libraries (1993). The Scripps Research Institute. La Jolla, Ca. U. S. A.

Cook, G. P., and Tomlinson, I. M (1995). The human immunoglobulin VH repertoire. Immunol. Today. 16: 237–242

Courtney, B. C., Williams, K. C. , and Schlager, J. J (1995). A phage display vector with improved stability, applicability and ease of manipulation. Gene. 165: 139-140

Cox, D. W., Markovic, V. D., and Teshima, I. E (1982). Genes for immunoglobulin heavy chains and for 1-antitrypsin are localized to specific regions of chromosome 14q. Nature. 297: 428-430

Deckmyn, H., and De Reys, S (1995). Functional effects of human antiplatelet antibodies. Semin. Thromb. Hemost.21: 46-58

de la Chapelle, A., Lenoir, A., Boue, G., Gallano, P., Huerre, C., Szajnert, M. F., Jeanpierre, M., Lalouel, M., and Kaplan, J. C (1983). Lamda Ig constant region genes are translocated to chromosome 8 in a Burkitt's lymphoma Nucl. Acids. Res. 11; 1133-1142

De Wildt, R. M. T., Hoet, R. M. A., van Venrooij, W. J., Tomlinson, I. M., and Winter, G (1999). Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. J. Mol. Biol. 285: 895-901

Dersimonian, H., Schwartz, R. S., Barrett, K. J., and Stollar, B. D (1987). Relationship of human variable region heavy chain germ-line genes to genes encoding anti-DNA. J. Immunol. 139: 2496-2501

Domiati-Saad, R., and Lipsky, P. E (1997). B Cell Superantigens: Potential Modifiers of the Normal Human B Cell Repertoire. Intern. Rev. Immunol. 14: 309-324

Duchosal, M. A., Eming, S., Fischer, P., Leturcq, D., Barbas III, C.F., McConahey, P. J., Caothien, R. H., Thornton, G. B., Dixon, F. J., and Burton, D. R (1992). Immunization of hu-PBL-SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries. Nature 355: 258-262

Fischer, P (1995). Expression des humanen Antikörperrepertoires mit Bakteriophagen: techniken, anwendungen, perspektiven. Biospektrum. 3: 26-29

Fischer, P (1998 ). Molekulare Charakterisierung humaner Autoantikörper durch Kombinatorische Phagen Display-Bibliotheken. Habilitation , Medizinischen Falkultät Charitè der Humboldt-Universität zu Berlin. pp143

Fischer, P., Jendreyko, N., Hoffmann, M., Lerch, H., Uttenreuther-Fischer, M. M., Chen, P. P., and Gaedicke, G (1999). Platelet reactive IgG antibodies cloned by phage display and panning with IVIG from patients with AITP. Br. J. Haematol. 105: 626-640

Fischer, P., Uttenreuther-Fischer, M. M., Naoe, S., and Gaedicke, G (1996 ). Kawasaki disease: update on diagnosis, treatment and a still controversial etiology. Pediatr. Hematol. Oncol. 13: 487-501

Gordon, J. M., Cohen, P., and Finlayson, J. S (1980). Levels of anti-A and anti-B in commercial immune globulins. Transfusion 26: 90-92

Graille, M., Stura, E. A., Corper, A. L., Sutton, B. J., Taussig, M. J., Charbonnier, J-B., and Silverman, G (2000). Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: Structural basis for recognition of B-cell receptors and superantigen activity. Proc. Natl. Acad. Sci. U.S.A. 97: 5399-5404

Graus, Y. F., de Baets, M. H., Parren, P. W., Berrih-Aknin, S., Wokke, J., van Breda Vriesman, P. J., Burton, D. R (1997). Human anti-nicotinic acetylcholine receptor recombinant Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies. J Immunol.158: 1919-1929.

Hillson, J. L., Karr, N. S., Oppliger, I. R., Mannik, M., and Sasso, E. H (1993). The structural basis of germline-encoded VH3 immunoglobulin binding to staphylococcal protein A. J. Exp. Med. 178: 331-336

Hoffmann, M., Uttenreuther-Fischer, M. M., Lerch, H., Gaedicke, G., and Fischer, P (2000). IVIG-bound IgG and IgM cloned by phage display from a healthy individual reveal the same restricted germ-line gene origin as in autoimmune thrombocytopenia. Clin. Exp. Immunol. 121:37-46

Honjo, T., and Matsuda, F (1995 ). Immunoglobulin heavy chain loci of mouse and human. In Immunoglobulin Genes. 2nd edition, ed. Honjo, T., and Alt, F. W. Academic Press. New York. P. 145-171

Hoogenboom, H. R (1997). Designing and optimizing library selection strategies for generating high-affinity antibodies. Trends Biotechnol. 15: 62-70

Huang, S. C., Jiang, R. H., Glas, A. M., and Milner, E. C. B (1996). Non-stochastic utilization of Ig V region genes in unselected human peripheral B cells. Mol. Immunol. 33: 553-560

Hurez, V., Kaveri, S. V., Mouhoub, A., Dietrich, G., Mani, J. C., Klatzmann, D., and Kazatchkine, M. D (1994). Anti-CD4 activity of normal human immunoglobulin G for therapeutic use (intravenous immunoglobulin, IVIG Therapeutic Immunol 1: 269-278

Huse, W. D., Sastry, L., Iverson, S. A., Kang, A. S., Alting-Meers, M., Burton, D. R., Benkovic, S. J., and Lerner, R. A (1989). Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science. 246: 1275-1281

Imbach, P., Wagner, H. P., Berchtold, W., Gaedicke, G., Hirt, A., Joller, P., Mueller-Eckhardt, C., Muller, B., Rossi, E (1985). Intravenous immunoglobulin versus oral corticosteroids in acute immune thrombocytopenic purpura in childhood. Lancet. 2: 464-468

James, K., and Bell, G. T (1987). Human monoclonal antibody production. Current status and future prospects. J Immunol Methods. 100: 5-40.

Jansson, B., Uhlèn, M., and Nygre, P-A (1998). All individual domains of staphylococcal protein A show Fab binding. FEMS Immunol. Med. Mirobiol. 20: 69-78

Jendreyko, N., Uttenreuther-Fischer, M. M., Lerch, H., Gaedicke, G., and Fischer, P (1998). Genetic origin of IgG antibodies cloned by phage display and antiidiotypic panning from three patients with autoimmune thrombocytopenia. Eur. J. Immunol. 28: 4236-4247

Jerne, N. K (1974). Towards a network theory of the immune system. Ann Immunol. (Inst. Pasteur) 125c: 373-389

Jones, T. D (1944). Diagnosis of rheumatic fever. JAMA 126: 481

Kabat, E. A., Wu, T. T., Reid-Miller, M., Perry, H. M., Gottesman, K. S., and Foeller, C (1991). Sequences of proteins of immunological interest . U.S. Dept. of Health and Human Services, Bethesda, MD, U.S.A

Kang, AS., Barbas III, C. F., Janda, K. D., Benkovic, S. J., and Lerner, R. A (1991a). Linkage of recognition and replication functions by assemblying combinatorial antibody Fab libraries along phage surfaces. Proc. Natl. Acad. Sci. U. S. A. 88: 4363 - 4366

Kang, A. S., Burton, D. R., and Lerner, R. A (1991b). Combinatorial immunoglobulin libraries in phage . Methods. Companion Methods Enzymol. 2: 111-118

Karpatkin, S (1997). Autoimmune (idiopathic) thrombocytopenic purpura. Lancet 349: 1531-1536.

Karray, S., Juompan, L., Maroun, R. C., Isenberg, D., Silverman, G. J., and Zouali, M (1998). Structural basis of the gp120 superantigen-binding site on human immunoglobulins. J. Immunol. 161: 6681-6688

Kearney, J. F., and Vakil, M (1986). Idiotype-directed interactions during ontogeny play a major role in the establishment of the adult B cell repertoire. Immunol. Rev. 94: 39-50

Kiefel, V., Santoso, S., Kaufmann, E., and Mueller-Eckhardt, C (1991). Autoantibodies against against platelet glycoprotein Ib/IX: a frequent finding in autoimmune thrombocytopenic purpura. Br. J. Hematol. 79: 256 - 262

Kimberly, R. P., Salmon, J. E., Bussel, J. B., Crow, M. K., and Hilgartner, M. W (1984). Modulation of mononuclear phagocyte function by intravenous gamma globulin. J. Immunol 132: 745-750

Kincade, P. W (1987). Experimental models for understanding B lymphocyte formation. Adv. Immunol. 41: 181-267

Kirkham, P. M., and Schroeder, H. W., Jr (1994). Antibody structure and the evolution of immunoglobulin V gene segments. Semin. Immunol. 6: 347-360

Köhler, G., and Milstein, C (1975). Continous cultures of fused cells secreting antibody of pre-defined specificity. Nature. 256: 495-497

Kondo, N., Kasahara, K., Kameyama, T., Suzuki, Y., Shimozawa, N., Tomatsu S., Nakashima Y., and Hori, T (1994). Intravenous immunoglobulins suppress immunoglobulin production by suppressing Ca2+-dependent signal transduction through Fcg receptors in B lymphocytes. Scand. J. Immunol 40: 37-42

Kondo, N., Ozawa, T., Mushiake, K., Motoyoshi, F., Kameyama, T., Kasahara, K., Kaneko, H, Yamashina M., Kato, Y., and Orii, T (1991). Suppression of immunoglobulin production of lymphocytes by intravenous immunoglobulin.J. Clin. Immunol. 11: 152-158

Kotzin, B. L (1996). Systemic lupus erythematosus. Cell. 85: 303-306

Kraj, P., Rao, S. P., Glas, A. M., Hardy, R. R., Milner, E. C. B., and Silberstein, L. E (1997). The human heavy chain Ig V region gene repertoire is biased at all stages of B cell ontogeny, including early pre-B cells. J. Immunol. 158: 5824-5832

Kuby, J (1997). Immunology. 3rd Edition. pp664. W. H. Freeman and Company. New York

Lam, L., Whitsett, C. F., McNicholl, J. M., Hodge, T. W., and Hooper, J (1993). Immunologically active proteins in intravenous immunoglobulin. Lancet 342: 678

Leffell, M. S (1997). The molecular basis for immune responses. In: Handbook of Human Immunology. Ed. Leffell, M. S., Donnenberg, A. D., Bias, W. B., and Rose, N. R. pp 660. CRC Press

Leucht, S., Uttenreuther-Fischer, M. M., Gaedicke, G., and Fischer, P (2001). The B cell superantigen-like interaction of intravenous immunoglobulin (IVIG) with Fab fragments of VH 3-23 and 3-30/3-30.5 germ-line gene origin cloned from a patient with Kawasaki disease is enhanced after IVIG therapy. Clin. Immunol. 99: 18-29

Leung, D. Y., Gately, M., Trumble, A., Ferguson-Darnell, B., Schlievert, P. M., and Picker, L. J (1995). Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin-12 production. J. Exp. Med 181: 747-753

Little, M., Breitling, F., Dübel, S., Fuchs, P., and Braunagel, M (1995 ). Human antibody libraries in Escherichia coli. J. Biotechnol. 41. 187 – 195

Little, M., Dübel, S., and Breitling, F (1997). Recent developments in antibody engineering. In: “Molecular Diagnosis of Infectious Diseases” in the series “Methods in Molecular Medicine. Vol 13, p. 555-580” ed. U. Reischl, Humana Press Inc . Totowa, N. Y.

Macchi, L., Rispal, P., Clofent-Sanchez, G., Pellegrin, J. -L., Nurden, P., Leng, B., and Nurden, A (1997). Anti-platelet antibodies in patients with systemic lupus erythematosus and the primary antiphospholipid antibody syndrome: their relationship with the observed thrombocytopenia. Br. J. Haematol. 98: 336-341

Malcolm, S., Barton, P., Murphy, C., Ferguson-Smith, M., A., Bentley, D. L., and Rabbits, T. H (1982). Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization. Proc. Natl. Acad. Sci. USA. 79: 4957-4961

Marchalonis, J. J., Kaymaz, H., Dedeoglu, F., Schluter, S. F., Yocum, D. E., and Edmundson, A. B (1992). Human autoantibodies reactive with synthetic autoantigens from T-cell receptor chain. Proc. Natl. Acad. Sci. U.S.A 89: 3325-3329

Matsuda, F., Ishii, K., Bourvagnet, P., Kuma, K., Hayashida, H, Miyata, T., and Honjo, T (1998). The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. J. Exp. Med. 188: 2151-2162

Matsuda, F., Shin, E. K., Nagoka, H., Matsumara, R., Haino, M., Fukita, Y., Takaishi, S., Imai, T., Riley, J. H., Anand, R., and Honjo, T (1993 ). Structure and physical map of 64 variable segments in the 3' 0.8-megabase region of the human immunoglobulin heavy-chain locus. Nature Genet. 3: 88-94

McCafferty, J., Griffiths, A. D., Winter, G., and Chiswell, D. J (1990). Phage antibodies: Filamentous phage displaying antibody variable domains. Nature 348: 552-554

Melchers, F., Karasuyama, H., Hassner, D., Bauer, S., Kudo, A., Sakaguchi, N., Jameson, B., and Rolink, A (1993). The surrogate light chain in B-cell development. Immunol. Today. 14: 60 - 68

Mouthon, L., Kaveri, S. V., Spalter, S. H., Lacroix-Desmazes, S., Lefranc, C., Desai, R., and Kazatchkine, M. D (1996). Mechanisms of action of intravenous immune globulin in immune-mediated diseases. Clin Exp Immunol. 104 (Suppl. 1): 3-9

Neshat, M. N., Goodglick, L., Lim, K., and Braun, J (2000). Mapping the B cell superantigen binding site for HIV-1 gp120 on a V(H)3 Ig. Int Immunol. 12: 305-312

Olee, T., Yang, P-M., Siminovitch, K. A., Olsen, N. J., Hillson, J., Wu, J., Kozin, F., Carson, D. A., and Chen, P. P (1991). Molecular Basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseases. J. Clin. Invest. 88: 193-203

Osei, A., Uttenreuther-Fischer, M. M., Lerch, H., Gaedicke, G., Fischer, P (2000). Restricted VH3 gene use in phage displayed Fab that are selected by IVIG. Arthritis Rheum. 43: 2722-2732

Pascual, V., Randen, I., Thompson, K., Sioud, M., Forre, O., Natvig, J., and Capra, J. D (1990). The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes. J Clin Invest. 86: 1320 - 1328.

Persson, M. A (1993). Combinatorial libraries. Intern. Rev. Immunol. 10: 153 - 163

Persson, M. A., Caothien, R. H., and Burton, D. R (1991). Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning.Proc. Natl. Acad. Sci. U. S. A. 86: 2432-2436

Potter, K. N., and Capra, J. D (1995 ). Immunoglobulin variable region gene segments in human autoantibodies. In Immunoglobulin Genes. 2nd edition, ed. Honjo, T., and Alt, F. W. Academic Press. New York. P. 379-396

Potter, K. N., Li, Y., Mageed, R. A., Jefferis, R., and Capra, J. D (1998). Anti-idiotypic antibody D12 and superantigen SpA both interact with human V(H)3-encoded antibodies on the external face of the heavy chain involving FR3. Mol. Immunol. 35: 1179-1187

Potter, K. N., Li, Y., Pascual, V., and Capra, J. D (1997). Staphylococcal Protein A Binding to VH3 Encoded Immunoglobulins. Intern. Rev. Immunol.14: 291-308

Quinti, I., Papetti, C., Paganelli, R., D'Amelio, R., Nisini, R., D'Offizi, G., and Aiuto, F (1987). Evaluation of the presence of RF-like activities in immunoglobulin preparations for intravenous use. IgG anti-IgE in intravenous Ig.J. Clin. Lab. Immunol. 24: 135-138

Rader, C., and Barbas III, C. F (1997). Phage display of combinatorial antibody libraries. Curr. Opin. Biotechnol. 8: 503-508

Rao, S. P., Riggs, J. M., Friedman, D. F., Scully, M. S., LeBien, T. W., and Silberstein, L. E (1999). Biased VH gene usage in early lineage human B cells: evidence for preferential Ig gene rearragement in the absence of selection. J. Immunol. 163: 2732-2740

Retter, M. W., and Nemazee, D (1998). Receptor Editing occurs frequently during normal B cell Development. J. Exp. Med. 7: 1231-1238

Rolink, A. and Melchers, F (1991). Molecular and cellular origins of B lymphocyte diversity. Cell. 66: 1081-1094

Rondot, S., Koch, J., Breitling, F., and Dubel, S (2001). A helper phage to improve single-chain antibody presentation in phage display. Nat. Biotechnol. 1 : 75-78

Sambrook, J., Fritsch, E. F., and Maniatis, T (1989). Molecular Cloning: A Laboratory Manual. 2nd Edition. Cold Spring Harbor Laboratory Press. Cold Spring Harbor.

Sanz, I., Dang, H., Takei, M., Talal, N., and Capra, J. D (1989 ). VH sequence of a human anti-Sm autoantibody. J. Immunol. 142: 883 - 887.

Sasano , M., Burton, D. R., and Silverman, G. J (1993). Molecular selection of human antibodies with an unconventional bacterial B cell superantigen. J. Immunol. 151 : 5822-5839

Sastry, L., Alting-Meers, M., Huse, W. D., Short, J. M., Sorge, J. A., Hay B. N., Janda, K. D., Benkovic, S. J., and Lerner, R. A (1989). Cloning of the immunoglobulin repertoire in Escherichia coli for generation of monoclonal catalytic antibodies: Construction of a heavy chain variable region-specific cDNA library. Proc. Natl. Acad. Sci. U. S. A. 86: 5728-5732

Schroeder, H., and Wang, J. Y (1990). Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life. Proc. Natl. Aca. Sci. USA 87: 6164-6150

Schroeder, H. W., Hillson, J. L., and Perlmutter, R. M (1990 ). Structure and evolution of mammalian VH families. Int. Immunol. 20: 41-50.

Shimozato, T., Iwata, M., Kawada, H., and Tamura, N (1991). Human immunoglobulin preparation for intravenous use induces elevation of cellular cyclic adenosine 3´:5´-monophosphate levels, resulting in suppression of tumor necrosis factor alpha and interleukin-1 production. Immunology 72: 497-501

Siegel, D. L., Chang, T. Y., Russell, S. L., and Bunya, V. Y (1997). Isolation of cell surface-specific human monoclonal antibodies using phage display and magnetically-activated cell sorting: applications in immunohematology. J. Immunol. Methods 206: 73-85

Silverman, G. J (1997). B-cell superantigens. Immunol. Today 18: 379-386

Silverman, G. J (1998). B cell superantigens: possible roles in immunodeficiency and autoimmunity. Semin. Immunol. 1: 43 - 55

Smith, G. P (1985). Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface. Science. 228: 1315-1316

Stollar, B. D (1989). Immunochemistry of DNA. Int Rev Immunol. 5: 1-22.

Tan, E. M., Cohen, A. S., Fries, J. F., Masi, A. T., McShane, D. J., Rothfield, N. F., Schaller, J. G., Talal, N., and Winchester, R. J (1982). The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25: 1271

Tomer, Y., Buskila, D., and Shoenfeld, Y (1993). Pathogenic significance and diagnostic value of lupus autoantibodies. Int. Arch. Allergy Immunol. 100: 293-306

Tomlinson, I. M., Walter, G., Marks, J. D., Llewelyn, M. B ., and Winter, G (1992 ). The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227: 776-798

Tomlinson, I. M (1997). V Base sequence directory. M. R. C. Center for Protein Engineering. Cambridge, U. K

Townsley-Fuchs, J., Neshat, M. S., Margolin, D. H., Braun, J. H., and Goodglick, L (1997). HIV-1 gp120: A Novel Viral B cell Superantigen. Int. Rev. Immunol. 14: 325-338

van Dijk, K. W., Mortari, F., Kirkham, P. M., Schroeder, H. W., and Milner, E. C (1993). The human immunoglobulin VH7 segment gene family consists of a small, polymorphic group of six to eight gene segments dispersed throughout the VH locus. Eur. J. Immunol. 23: 832-839

Vassilev, T., Gelin, C., Kaveri, S. V., Zilber, M-T., Boumsell, L., Kazatchkine, and M. D (1993). Antibodies to the CD5 molecule in normal human immunoglobulins for therapeutic use (intravenous immunoglobulin, IVIG). Clin. Exp. Immunol. 92: 369-372

Verhoeyen, M. E., and Windust, J. H. C (1996). Advances in antibody engineering. In Molecular Immunology. 2nd edition, p 283-325. Editors: Hames, B. D., and Glover, D. M. IRL Press, Oxford Univ. Press, New York, U. S. A

White, J., Herman, A., Pullen, A. M., Kubo, R., Kappler, J. W., and Marrack, P (1989). The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell 56: 27-35

Williams, S. C., Frippiat, J-P., Tomlinson, I. M., Ignatovich, O., Lefranc, M-P., and Winter, G (1996). Sequence and evolution of the human germline V lambda repetoire. J. Mol. Biol. 264: 220-232

Wolf, H. M., and Eibl, M. M (1996). Immunomodulatory effect of immunoglobulins. Clin. Exp Rheumatol 14 (Suppl. 15): S17-S25.

Woods, V. L., Oh, E. H., Mason, D., and McMillan, R ( 1984 ). Autoantibodies against the platelet glycoprotein IIb/IIIa complex in patients with chronic ITP. Blood. 63: 368 – 375

Xu, H., Frojmovic, M. M., Wong, T., and Rauch, J (1995). Inhibition of platelet aggregation by an SLE-derived human hybridoma autoantibody against an activation-dependent antigen. Thromb Haemos 74: 1152-1162

Yang, Y.-Y., Fischer, P., Leu, S.-Y., Zhu, M., Woods, V. L., and Chen, P. P (1999 ). Possible presence of enhancing antibodies in idiopathic thrombocytopenic purpura. Br. J. Haematol. 104: 69–80


© Die inhaltliche Zusammenstellung und Aufmachung dieser Publikation sowie die elektronische Verarbeitung sind urheberrechtlich geschützt. Jede Verwertung, die nicht ausdrücklich vom Urheberrechtsgesetz zugelassen ist, bedarf der vorherigen Zustimmung. Das gilt insbesondere für die Vervielfältigung, die Bearbeitung und Einspeicherung und Verarbeitung in elektronische Systeme.
DiML DTD Version 4.0Zertifizierter Dokumentenserver
der Humboldt-Universität zu Berlin
HTML generated:
03.11.2006