Modeling the MHC-I pathwayBjörn Peters178576#36291.11.1.110576#357111.1.212352#3781.1.313445#378142152.1162.1.1172.1.22.1.3182.219202.3212.4115#36205#39240#3122315#56216#40508#34623242.52.5.12.625520#420262.727521#4212829483#5482.830174#36316#4031508#3583233342.935507#554362.103373.1383.239576#33340508#384413.342242#25576#336433.444291#288304#9145304#27146314#4547304#2713.4.148493.4.25051304#2713.552287#249533.6543.755564574.14.1.1584.1.24.1.3594.1.4363#2914.1.56061363#2914.24.2.16263496#31264551#329654.2.24.3664.3.1166#3755#21262#3767360#75126#53146#2068104#524.3.269300#1004.3.2.1101#87704.3.2.2714.3.2.379#3688#37323#165724.44.4.14.4.1.14.4.1.2734.4.1.34.4.1.44.4.24.4.2.174586#47975586#45876435#405774.4.2.2784.4.34.4.3.179600#30780814.4.3.2828384854.4.3.3864.4.3.4874.588894.690591929394959669798 References99100101102103104105106 Abbreviations107 Acknowledgments108109 Lebenslauf110 Publikationen111 Erklärung112enTable of contentsHelp References Agatonovic-Kustrin, S. and Beresford, R. (2000): Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research, J Pharm Biomed Anal 22 [5], pp.717-27. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10815714 Aki, M.; Shimbara, N.; Takashina, M.; Akiyama, K.; Kagawa, S.; Tamura, T.; Tanahashi, N.; Yoshimura, T.; Tanaka, K. and Ichihara, A. (1994): Interferon-gamma induces different subunit organizations and functional diversity of proteasomes, J Biochem (Tokyo) 115 [2], pp.257-69. Altuvia, Y.; Schueler, O. and Margalit, H. (1995): Ranking potential binding peptides to MHC molecules by a computational threading approach, J Mol Biol 249 [2], pp.244-50. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7540211 Ayalon, O.; Hughes, E. A.; Cresswell, P.; Lee, J.; O'Donnell, L.; Pardi, R. and Bender, J. R. (1998): Induction of transporter associated with antigen processing by interferon gamma confers endothelial cell cytoprotection against natural killer-mediated lysis, Proc Natl Acad Sci U S A 95 [5], pp.2435-40. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9482903 Boes, B.; Hengel, H.; Ruppert, T.; Multhaup, G.; Koszinowski, U. H. and Kloetzel, P. M. (1994): Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes, J Exp Med 179 [3], pp.901-9. Bradley, Andrew P (1997): The use of the area under the ROC curve in the evaluation of machine learning algorithms, Pattern Recognition 30 [7], pp.1145-1159. Breiman, L.; Friedman, J.H.; Olshen, R.A. and Stone, C. J. (1984): Classification and Regression Trees, CRC Press. Brusic, V.; van Endert, P.; Zeleznikow, J.; Daniel, S.; Hammer, J. and Petrovsky, N. (1999): A neural network model approach to the study of human TAP transporter, In Silico Biol 1 [2], pp.109-21. Cardozo, C. and Kohanski, R. A. (1998): Altered properties of the branched chain amino acid-preferring activity contribute to increased cleavages after branched chain residues by the "immunoproteasome", J Biol Chem 273 [27], pp.16764-70. http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jbc.org/cgi/content/full/273/27/16764 http://www.jbc.org/cgi/content/full/273/27/16764

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