<?xml version="1.0" encoding="ISO-8859-1"?><cms:container xmlns:cms="http://edoc.hu-berlin.de/diml/module/cms"><cms:document><cms:meta><cms:entry id="front" part="front" ref="front" type="front"/><cms:entry type="title">Modeling the MHC-I pathway</cms:entry><cms:entry type="author">Björn Peters</cms:entry><cms:entry id="chapter1" part="chapter1" ref="chapter1" type="chapter">1</cms:entry><cms:entry id="N100A2" part="chapter1" ref="N100A2" type="pagenumber">7</cms:entry><cms:entry id="_Ref32582744" part="chapter1" ref="_Ref32582744" type="link"/><cms:entry id="N100D7" part="chapter1" ref="N100D7" type="pagenumber">8</cms:entry><cms:entry id="N100DB" part="chapter1" ref="N100DB" type="mm">576#362</cms:entry><cms:entry id="_Ref32584319" part="chapter1" ref="_Ref32584319" type="link"/><cms:entry id="N100EF" part="chapter1" ref="N100EF" type="pagenumber">9</cms:entry><cms:entry id="N10104" part="chapter1" ref="N10104" type="section">1.1</cms:entry><cms:entry id="N10110" part="chapter1" ref="N10110" type="subsection">1.1.1</cms:entry><cms:entry id="N1011B" part="chapter1" ref="N1011B" type="pagenumber">10</cms:entry><cms:entry id="N10122" part="chapter1" ref="N10122" type="mm">576#357</cms:entry><cms:entry id="_Ref32569297" part="chapter1" ref="_Ref32569297" type="link"/><cms:entry id="N1014A" part="chapter1" ref="N1014A" type="pagenumber">11</cms:entry><cms:entry id="N10166" part="chapter1" ref="N10166" type="subsection">1.1.2</cms:entry><cms:entry id="N1017C" part="chapter1" ref="N1017C" type="pagenumber">12</cms:entry><cms:entry id="N1018B" part="chapter1" ref="N1018B" type="mm">352#378</cms:entry><cms:entry id="_Ref32641617" part="chapter1" ref="_Ref32641617" type="link"/><cms:entry id="N1019C" part="chapter1" ref="N1019C" type="subsection">1.1.3</cms:entry><cms:entry id="N101AA" part="chapter1" ref="N101AA" type="pagenumber">13</cms:entry><cms:entry id="N101B8" part="chapter1" ref="N101B8" type="mm">445#378</cms:entry><cms:entry id="_Ref32649286" part="chapter1" ref="_Ref32649286" type="link"/><cms:entry id="N101C7" part="chapter1" ref="N101C7" type="pagenumber">14</cms:entry><cms:entry id="chapter2" part="chapter2" ref="chapter2" type="chapter">2</cms:entry><cms:entry id="_Ref33009381" part="chapter2" ref="_Ref33009381" type="link"/><cms:entry id="N101D6" part="chapter2" ref="N101D6" type="pagenumber">15</cms:entry><cms:entry id="N1020C" part="chapter2" ref="N1020C" type="section">2.1</cms:entry><cms:entry id="_Ref32380251" part="chapter2" ref="_Ref32380251" type="link"/><cms:entry id="N1021A" part="chapter2" ref="N1021A" type="pagenumber">16</cms:entry><cms:entry id="N10232" part="chapter2" ref="N10232" type="subsection">2.1.1</cms:entry><cms:entry id="N10248" part="chapter2" ref="N10248" type="pagenumber">17</cms:entry><cms:entry id="N10255" part="chapter2" ref="N10255" type="subsection">2.1.2</cms:entry><cms:entry id="N10261" part="chapter2" ref="N10261" type="subsection">2.1.3</cms:entry><cms:entry id="N10270" part="chapter2" ref="N10270" type="pagenumber">18</cms:entry><cms:entry id="N102A8" part="chapter2" ref="N102A8" type="section">2.2</cms:entry><cms:entry id="_Ref33246561" part="chapter2" ref="_Ref33246561" type="link"/><cms:entry id="N102AF" part="chapter2" ref="N102AF" type="pagenumber">19</cms:entry><cms:entry id="N102CF" part="chapter2" ref="N102CF" type="pagenumber">20</cms:entry><cms:entry id="N102E2" part="chapter2" ref="N102E2" type="section">2.3</cms:entry><cms:entry id="_Ref33246623" part="chapter2" ref="_Ref33246623" type="link"/><cms:entry id="N102FD" part="chapter2" ref="N102FD" type="pagenumber">21</cms:entry><cms:entry id="N10307" part="chapter2" ref="N10307" type="section">2.4</cms:entry><cms:entry id="_Ref31868739" part="chapter2" ref="_Ref31868739" type="link"/><cms:entry id="_Ref31864971" part="chapter2" ref="_Ref31864971" type="link"/><cms:entry id="N10320" part="chapter2" ref="N10320" type="table"/><cms:entry id="N10363" part="chapter2" ref="N10363" type="mm">115#36</cms:entry><cms:entry id="eq_mat_score" part="chapter2" ref="eq_mat_score" type="link"/><cms:entry id="N103DF" part="chapter2" ref="N103DF" type="table"/><cms:entry id="N1041A" part="chapter2" ref="N1041A" type="mm">205#39</cms:entry><cms:entry id="eq_norm" part="chapter2" ref="eq_norm" type="link"/><cms:entry id="N10479" part="chapter2" ref="N10479" type="table"/><cms:entry id="N104B0" part="chapter2" ref="N104B0" type="mm">240#31</cms:entry><cms:entry id="N10503" part="chapter2" ref="N10503" type="table"/><cms:entry id="N10532" part="chapter2" ref="N10532" type="pagenumber">22</cms:entry><cms:entry id="N10536" part="chapter2" ref="N10536" type="mm">315#56</cms:entry><cms:entry id="N10577" part="chapter2" ref="N10577" type="table"/><cms:entry id="N105B2" part="chapter2" ref="N105B2" type="mm">216#40</cms:entry><cms:entry id="eq_smm_minimize" part="chapter2" ref="eq_smm_minimize" type="link"/><cms:entry id="N105FB" part="chapter2" ref="N105FB" type="mm">508#346</cms:entry><cms:entry id="_Ref31814763" part="chapter2" ref="_Ref31814763" type="link"/><cms:entry id="N10609" part="chapter2" ref="N10609" type="pagenumber">23</cms:entry><cms:entry id="N10626" part="chapter2" ref="N10626" type="table"/><cms:entry id="_Ref31815443" part="chapter2" ref="_Ref31815443" type="link"/><cms:entry id="_Ref33246221" part="chapter2" ref="_Ref33246221" type="link"/><cms:entry id="_Ref33246776" part="chapter2" ref="_Ref33246776" type="link"/><cms:entry id="N10EA2" part="chapter2" ref="N10EA2" type="pagenumber">24</cms:entry><cms:entry id="N10EA8" part="chapter2" ref="N10EA8" type="section">2.5</cms:entry><cms:entry id="N10EB8" part="chapter2" ref="N10EB8" type="subsection">2.5.1</cms:entry><cms:entry id="N10EC2" part="chapter2" ref="N10EC2" type="section">2.6</cms:entry><cms:entry id="_Ref33246788" part="chapter2" ref="_Ref33246788" type="link"/><cms:entry id="N10ED0" part="chapter2" ref="N10ED0" type="pagenumber">25</cms:entry><cms:entry id="N10EDF" part="chapter2" ref="N10EDF" type="mm">520#420</cms:entry><cms:entry id="_Ref31814732" part="chapter2" ref="_Ref31814732" type="link"/><cms:entry id="_Ref31814869" part="chapter2" ref="_Ref31814869" type="link"/><cms:entry id="N10EF3" part="chapter2" ref="N10EF3" type="pagenumber">26</cms:entry><cms:entry id="N10EFA" part="chapter2" ref="N10EFA" type="table"/><cms:entry id="_Ref31815482" part="chapter2" ref="_Ref31815482" type="link"/><cms:entry id="N1114B" part="chapter2" ref="N1114B" type="section">2.7</cms:entry><cms:entry id="_Ref32380054" part="chapter2" ref="_Ref32380054" type="link"/><cms:entry id="N1115D" part="chapter2" ref="N1115D" type="pagenumber">27</cms:entry><cms:entry id="N11164" part="chapter2" ref="N11164" type="mm">521#421</cms:entry><cms:entry id="_Ref32227881" part="chapter2" ref="_Ref32227881" type="link"/><cms:entry id="N11179" part="chapter2" ref="N11179" type="pagenumber">28</cms:entry><cms:entry id="N1118F" part="chapter2" ref="N1118F" type="pagenumber">29</cms:entry><cms:entry id="N11193" part="chapter2" ref="N11193" type="mm">483#548</cms:entry><cms:entry id="_Ref31814662" part="chapter2" ref="_Ref31814662" type="link"/><cms:entry id="_Ref31814839" part="chapter2" ref="_Ref31814839" type="link"/><cms:entry id="N111AC" part="chapter2" ref="N111AC" type="section">2.8</cms:entry><cms:entry id="_Ref33246910" part="chapter2" ref="_Ref33246910" type="link"/><cms:entry id="N111B3" part="chapter2" ref="N111B3" type="pagenumber">30</cms:entry><cms:entry id="N111CC" part="chapter2" ref="N111CC" type="table"/><cms:entry id="N1120B" part="chapter2" ref="N1120B" type="mm">174#36</cms:entry><cms:entry id="eq_pair_score" part="chapter2" ref="eq_pair_score" type="link"/><cms:entry id="N11259" part="chapter2" ref="N11259" type="table"/><cms:entry id="N11288" part="chapter2" ref="N11288" type="mm">316#40</cms:entry><cms:entry id="eq_pair_minimize" part="chapter2" ref="eq_pair_minimize" type="link"/><cms:entry id="N112D4" part="chapter2" ref="N112D4" type="pagenumber">31</cms:entry><cms:entry id="N112DF" part="chapter2" ref="N112DF" type="mm">508#358</cms:entry><cms:entry id="_Ref31815280" part="chapter2" ref="_Ref31815280" type="link"/><cms:entry id="N112FF" part="chapter2" ref="N112FF" type="pagenumber">32</cms:entry><cms:entry id="N1131C" part="chapter2" ref="N1131C" type="table"/><cms:entry id="_Ref31815586" part="chapter2" ref="_Ref31815586" type="link"/><cms:entry id="N11B6D" part="chapter2" ref="N11B6D" type="pagenumber">33</cms:entry><cms:entry id="N12C72" part="chapter2" ref="N12C72" type="pagenumber">34</cms:entry><cms:entry id="N12C7F" part="chapter2" ref="N12C7F" type="section">2.9</cms:entry><cms:entry id="_Ref33246928" part="chapter2" ref="_Ref33246928" type="link"/><cms:entry id="N12C90" part="chapter2" ref="N12C90" type="pagenumber">35</cms:entry><cms:entry id="N12C94" part="chapter2" ref="N12C94" type="mm">507#554</cms:entry><cms:entry id="_Ref31815354" part="chapter2" ref="_Ref31815354" type="link"/><cms:entry id="N12CA5" part="chapter2" ref="N12CA5" type="pagenumber">36</cms:entry><cms:entry id="N12CAB" part="chapter2" ref="N12CAB" type="section">2.10</cms:entry><cms:entry id="chapter3" part="chapter3" ref="chapter3" type="chapter">3</cms:entry><cms:entry id="_Ref32584641" part="chapter3" ref="_Ref32584641" type="link"/><cms:entry id="N12CBF" part="chapter3" ref="N12CBF" type="pagenumber">37</cms:entry><cms:entry id="N12D04" part="chapter3" ref="N12D04" type="section">3.1</cms:entry><cms:entry id="_Ref32381199" part="chapter3" ref="_Ref32381199" type="link"/><cms:entry id="N12D19" part="chapter3" ref="N12D19" type="pagenumber">38</cms:entry><cms:entry id="N12D61" part="chapter3" ref="N12D61" type="section">3.2</cms:entry><cms:entry id="_Ref33247930" part="chapter3" ref="_Ref33247930" type="link"/><cms:entry id="N12D76" part="chapter3" ref="N12D76" type="pagenumber">39</cms:entry><cms:entry id="N12D7A" part="chapter3" ref="N12D7A" type="mm">576#333</cms:entry><cms:entry id="_Ref31865584" part="chapter3" ref="_Ref31865584" type="link"/><cms:entry id="N12D9D" part="chapter3" ref="N12D9D" type="pagenumber">40</cms:entry><cms:entry id="N12DA1" part="chapter3" ref="N12DA1" type="mm">508#384</cms:entry><cms:entry id="_Ref33011144" part="chapter3" ref="_Ref33011144" type="link"/><cms:entry id="_Ref33011149" part="chapter3" ref="_Ref33011149" type="link"/><cms:entry id="N12DC7" part="chapter3" ref="N12DC7" type="table"/><cms:entry id="_Ref31864755" part="chapter3" ref="_Ref31864755" type="link"/><cms:entry id="_Ref31864761" part="chapter3" ref="_Ref31864761" type="link"/><cms:entry id="N12DD4" part="chapter3" ref="N12DD4" type="pagenumber">41</cms:entry><cms:entry id="N13603" part="chapter3" ref="N13603" type="section">3.3</cms:entry><cms:entry id="_Ref33247957" part="chapter3" ref="_Ref33247957" type="link"/><cms:entry id="N1361D" part="chapter3" ref="N1361D" type="pagenumber">42</cms:entry><cms:entry id="N13624" part="chapter3" ref="N13624" type="table"/><cms:entry id="N13657" part="chapter3" ref="N13657" type="mm">242#25</cms:entry><cms:entry id="eq_tap_cn_score" part="chapter3" ref="eq_tap_cn_score" type="link"/><cms:entry id="N1368F" part="chapter3" ref="N1368F" type="mm">576#336</cms:entry><cms:entry id="_Ref32384610" part="chapter3" ref="_Ref32384610" type="link"/><cms:entry id="N136A3" part="chapter3" ref="N136A3" type="pagenumber">43</cms:entry><cms:entry id="N136B1" part="chapter3" ref="N136B1" type="section">3.4</cms:entry><cms:entry id="_Ref32381227" part="chapter3" ref="_Ref32381227" type="link"/><cms:entry id="_Ref32381458" part="chapter3" ref="_Ref32381458" type="link"/><cms:entry id="_Ref33192811" part="chapter3" ref="_Ref33192811" type="link"/><cms:entry id="_Ref33192817" part="chapter3" ref="_Ref33192817" type="link"/><cms:entry id="N136D6" part="chapter3" ref="N136D6" type="pagenumber">44</cms:entry><cms:entry id="N136DA" part="chapter3" ref="N136DA" type="mm">291#288</cms:entry><cms:entry id="_Ref31974165" part="chapter3" ref="_Ref31974165" type="link"/><cms:entry id="_Ref31872151" part="chapter3" ref="_Ref31872151" type="link"/><cms:entry id="N136F9" part="chapter3" ref="N136F9" type="table"/><cms:entry id="N1372C" part="chapter3" ref="N1372C" type="mm">304#91</cms:entry><cms:entry id="eq_tap_sum_precursor_score" part="chapter3" ref="eq_tap_sum_precursor_score" type="link"/><cms:entry id="N1375E" part="chapter3" ref="N1375E" type="pagenumber">45</cms:entry><cms:entry id="N13775" part="chapter3" ref="N13775" type="mm">304#271</cms:entry><cms:entry id="_Ref31870082" part="chapter3" ref="_Ref31870082" type="link"/><cms:entry id="N13796" part="chapter3" ref="N13796" type="pagenumber">46</cms:entry><cms:entry id="N137A1" part="chapter3" ref="N137A1" type="table"/><cms:entry id="N137D0" part="chapter3" ref="N137D0" type="mm">314#45</cms:entry><cms:entry id="eq_tap_alpha_score" part="chapter3" ref="eq_tap_alpha_score" type="link"/><cms:entry id="N13810" part="chapter3" ref="N13810" type="pagenumber">47</cms:entry><cms:entry id="N13823" part="chapter3" ref="N13823" type="mm">304#271</cms:entry><cms:entry id="_Ref31973163" part="chapter3" ref="_Ref31973163" type="link"/><cms:entry id="N13836" part="chapter3" ref="N13836" type="subsection">3.4.1</cms:entry><cms:entry id="N1383A" part="chapter3" ref="N1383A" type="pagenumber">48</cms:entry><cms:entry id="N1385E" part="chapter3" ref="N1385E" type="table"/><cms:entry id="_Ref31875911" part="chapter3" ref="_Ref31875911" type="link"/><cms:entry id="_Ref32059657" part="chapter3" ref="_Ref32059657" type="link"/><cms:entry id="N1386B" part="chapter3" ref="N1386B" type="pagenumber">49</cms:entry><cms:entry id="N13A5D" part="chapter3" ref="N13A5D" type="subsection">3.4.2</cms:entry><cms:entry id="N13A61" part="chapter3" ref="N13A61" type="pagenumber">50</cms:entry><cms:entry id="N13A8E" part="chapter3" ref="N13A8E" type="pagenumber">51</cms:entry><cms:entry id="N13A92" part="chapter3" ref="N13A92" type="mm">304#271</cms:entry><cms:entry id="_Ref31973038" part="chapter3" ref="_Ref31973038" type="link"/><cms:entry id="N13ABA" part="chapter3" ref="N13ABA" type="section">3.5</cms:entry><cms:entry id="_Ref32381550" part="chapter3" ref="_Ref32381550" type="link"/><cms:entry id="_Ref33014095" part="chapter3" ref="_Ref33014095" type="link"/><cms:entry id="N13AC4" part="chapter3" ref="N13AC4" type="pagenumber">52</cms:entry><cms:entry id="N13AD6" part="chapter3" ref="N13AD6" type="mm">287#249</cms:entry><cms:entry id="_Ref31974014" part="chapter3" ref="_Ref31974014" type="link"/><cms:entry id="N13AEB" part="chapter3" ref="N13AEB" type="pagenumber">53</cms:entry><cms:entry id="N13B05" part="chapter3" ref="N13B05" type="table"/><cms:entry id="_Ref31975329" part="chapter3" ref="_Ref31975329" type="link"/><cms:entry id="N13C3F" part="chapter3" ref="N13C3F" type="section">3.6</cms:entry><cms:entry id="N13C43" part="chapter3" ref="N13C43" type="pagenumber">54</cms:entry><cms:entry id="N13C5F" part="chapter3" ref="N13C5F" type="section">3.7</cms:entry><cms:entry id="N13C6C" part="chapter3" ref="N13C6C" type="pagenumber">55</cms:entry><cms:entry id="N13C76" part="chapter3" ref="N13C76" type="pagenumber">56</cms:entry><cms:entry id="chapter4" part="chapter4" ref="chapter4" type="chapter">4</cms:entry><cms:entry id="_Ref32584621" part="chapter4" ref="_Ref32584621" type="link"/><cms:entry id="_Ref32584773" part="chapter4" ref="_Ref32584773" type="link"/><cms:entry id="N13C87" part="chapter4" ref="N13C87" type="pagenumber">57</cms:entry><cms:entry id="N13CB1" part="chapter4" ref="N13CB1" type="section">4.1</cms:entry><cms:entry id="_Ref32398535" part="chapter4" ref="_Ref32398535" type="link"/><cms:entry id="N13CD3" part="chapter4" ref="N13CD3" type="subsection">4.1.1</cms:entry><cms:entry id="N13CD7" part="chapter4" ref="N13CD7" type="pagenumber">58</cms:entry><cms:entry id="N13CF2" part="chapter4" ref="N13CF2" type="subsection">4.1.2</cms:entry><cms:entry id="N13D03" part="chapter4" ref="N13D03" type="subsection">4.1.3</cms:entry><cms:entry id="N13D0E" part="chapter4" ref="N13D0E" type="pagenumber">59</cms:entry><cms:entry id="N13D14" part="chapter4" ref="N13D14" type="subsection">4.1.4</cms:entry><cms:entry id="N13D2E" part="chapter4" ref="N13D2E" type="mm">363#291</cms:entry><cms:entry id="_Ref32062901" part="chapter4" ref="_Ref32062901" type="link"/><cms:entry id="_Ref32062906" part="chapter4" ref="_Ref32062906" type="link"/><cms:entry id="N13D41" part="chapter4" ref="N13D41" type="subsection">4.1.5</cms:entry><cms:entry id="N13D45" part="chapter4" ref="N13D45" type="pagenumber">60</cms:entry><cms:entry id="N13D61" part="chapter4" ref="N13D61" type="pagenumber">61</cms:entry><cms:entry id="N13D65" part="chapter4" ref="N13D65" type="mm">363#291</cms:entry><cms:entry id="_Ref32063189" part="chapter4" ref="_Ref32063189" type="link"/><cms:entry id="N13D76" part="chapter4" ref="N13D76" type="section">4.2</cms:entry><cms:entry id="_Ref32398591" part="chapter4" ref="_Ref32398591" type="link"/><cms:entry id="N13D84" part="chapter4" ref="N13D84" type="subsection">4.2.1</cms:entry><cms:entry id="N13D8B" part="chapter4" ref="N13D8B" type="pagenumber">62</cms:entry><cms:entry id="N13D9F" part="chapter4" ref="N13D9F" type="pagenumber">63</cms:entry><cms:entry id="N13DA3" part="chapter4" ref="N13DA3" type="mm">496#312</cms:entry><cms:entry id="_Ref32120065" part="chapter4" ref="_Ref32120065" type="link"/><cms:entry id="N13DBC" part="chapter4" ref="N13DBC" type="pagenumber">64</cms:entry><cms:entry id="N13DC0" part="chapter4" ref="N13DC0" type="mm">551#329</cms:entry><cms:entry id="_Ref32120122" part="chapter4" ref="_Ref32120122" type="link"/><cms:entry id="N13DE4" part="chapter4" ref="N13DE4" type="pagenumber">65</cms:entry><cms:entry id="N13DEE" part="chapter4" ref="N13DEE" type="subsection">4.2.2</cms:entry><cms:entry id="N13E0C" part="chapter4" ref="N13E0C" type="section">4.3</cms:entry><cms:entry id="_Ref32398607" part="chapter4" ref="_Ref32398607" type="link"/><cms:entry id="N13E13" part="chapter4" ref="N13E13" type="pagenumber">66</cms:entry><cms:entry id="N13E18" part="chapter4" ref="N13E18" type="subsection">4.3.1</cms:entry><cms:entry id="_Ref32146955" part="chapter4" ref="_Ref32146955" type="link"/><cms:entry id="N13E25" part="chapter4" ref="N13E25" type="table"/><cms:entry id="N13E60" part="chapter4" ref="N13E60" type="mm">166#37</cms:entry><cms:entry id="eq_sum_amount" part="chapter4" ref="eq_sum_amount" type="link"/><cms:entry id="N13ECB" part="chapter4" ref="N13ECB" type="table"/><cms:entry id="N13F12" part="chapter4" ref="N13F12" type="mm">55#21</cms:entry><cms:entry id="eq_sig_amount" part="chapter4" ref="eq_sig_amount" type="link"/><cms:entry id="N13F9D" part="chapter4" ref="N13F9D" type="table"/><cms:entry id="N13FD0" part="chapter4" ref="N13FD0" type="mm">262#37</cms:entry><cms:entry id="eq_sig_conv" part="chapter4" ref="eq_sig_conv" type="link"/><cms:entry id="N1401D" part="chapter4" ref="N1401D" type="pagenumber">67</cms:entry><cms:entry id="N14028" part="chapter4" ref="N14028" type="table"/><cms:entry id="N1404F" part="chapter4" ref="N1404F" type="mm">360#75</cms:entry><cms:entry id="eq_mass_balance" part="chapter4" ref="eq_mass_balance" type="link"/><cms:entry id="N14081" part="chapter4" ref="N14081" type="table"/><cms:entry id="N140B8" part="chapter4" ref="N140B8" type="mm">126#53</cms:entry><cms:entry id="eq_mass_balance_norm" part="chapter4" ref="eq_mass_balance_norm" type="link"/><cms:entry id="N14118" part="chapter4" ref="N14118" type="table"/><cms:entry id="N1414B" part="chapter4" ref="N1414B" type="mm">146#20</cms:entry><cms:entry id="eq_mass_balance_constrained" part="chapter4" ref="eq_mass_balance_constrained" type="link"/><cms:entry id="N14191" part="chapter4" ref="N14191" type="pagenumber">68</cms:entry><cms:entry id="N14198" part="chapter4" ref="N14198" type="table"/><cms:entry id="N141DB" part="chapter4" ref="N141DB" type="mm">104#52</cms:entry><cms:entry id="eq_mass_balance_regularization_term" part="chapter4" ref="eq_mass_balance_regularization_term" type="link"/><cms:entry id="N14257" part="chapter4" ref="N14257" type="subsection">4.3.2</cms:entry><cms:entry id="_Ref32148190" part="chapter4" ref="_Ref32148190" type="link"/><cms:entry id="N1426A" part="chapter4" ref="N1426A" type="table"/><cms:entry id="N1429D" part="chapter4" ref="N1429D" type="pagenumber">69</cms:entry><cms:entry id="N142A1" part="chapter4" ref="N142A1" type="mm">300#100</cms:entry><cms:entry id="eq_general_rates" part="chapter4" ref="eq_general_rates" type="link"/><cms:entry id="N142F2" part="chapter4" ref="N142F2" type="block">4.3.2.1</cms:entry><cms:entry id="N142FF" part="chapter4" ref="N142FF" type="table"/><cms:entry id="N1434A" part="chapter4" ref="N1434A" type="mm">101#87</cms:entry><cms:entry id="eq_procession_rate" part="chapter4" ref="eq_procession_rate" type="link"/><cms:entry id="N143A4" part="chapter4" ref="N143A4" type="pagenumber">70</cms:entry><cms:entry id="N143AA" part="chapter4" ref="N143AA" type="block">4.3.2.2</cms:entry><cms:entry id="N143C4" part="chapter4" ref="N143C4" type="mm"/><cms:entry id="_Ref32136747" part="chapter4" ref="_Ref32136747" type="link"/><cms:entry id="_Ref32136751" part="chapter4" ref="_Ref32136751" type="link"/><cms:entry id="N143E3" part="chapter4" ref="N143E3" type="pagenumber">71</cms:entry><cms:entry id="N143E9" part="chapter4" ref="N143E9" type="block">4.3.2.3</cms:entry><cms:entry id="N143FA" part="chapter4" ref="N143FA" type="table"/><cms:entry id="N14441" part="chapter4" ref="N14441" type="mm">79#36</cms:entry><cms:entry id="eq_rate_constant_1" part="chapter4" ref="eq_rate_constant_1" type="link"/><cms:entry id="N14492" part="chapter4" ref="N14492" type="table"/><cms:entry id="N144D9" part="chapter4" ref="N144D9" type="mm">88#37</cms:entry><cms:entry id="eq_rate_constant_2" part="chapter4" ref="eq_rate_constant_2" type="link"/><cms:entry id="N14540" part="chapter4" ref="N14540" type="table"/><cms:entry id="N14573" part="chapter4" ref="N14573" type="mm">323#165</cms:entry><cms:entry id="eq_distance_rate_eq" part="chapter4" ref="eq_distance_rate_eq" type="link"/><cms:entry id="N145A5" part="chapter4" ref="N145A5" type="pagenumber">72</cms:entry><cms:entry id="N145F2" part="chapter4" ref="N145F2" type="section">4.4</cms:entry><cms:entry id="_Ref32398878" part="chapter4" ref="_Ref32398878" type="link"/><cms:entry id="N145FA" part="chapter4" ref="N145FA" type="subsection">4.4.1</cms:entry><cms:entry id="_Ref32406943" part="chapter4" ref="_Ref32406943" type="link"/><cms:entry id="N1460B" part="chapter4" ref="N1460B" type="block">4.4.1.1</cms:entry><cms:entry id="N14614" part="chapter4" ref="N14614" type="block">4.4.1.2</cms:entry><cms:entry id="N14618" part="chapter4" ref="N14618" type="pagenumber">73</cms:entry><cms:entry id="N14625" part="chapter4" ref="N14625" type="block">4.4.1.3</cms:entry><cms:entry id="N1462E" part="chapter4" ref="N1462E" type="block">4.4.1.4</cms:entry><cms:entry id="_Ref32143394" part="chapter4" ref="_Ref32143394" type="link"/><cms:entry id="N1463B" part="chapter4" ref="N1463B" type="subsection">4.4.2</cms:entry><cms:entry id="N14640" part="chapter4" ref="N14640" type="block">4.4.2.1</cms:entry><cms:entry id="_Ref33194490" part="chapter4" ref="_Ref33194490" type="link"/><cms:entry id="N1464A" part="chapter4" ref="N1464A" type="pagenumber">74</cms:entry><cms:entry id="N14655" part="chapter4" ref="N14655" type="mm">586#479</cms:entry><cms:entry id="_Ref32143106" part="chapter4" ref="_Ref32143106" type="link"/><cms:entry id="N14668" part="chapter4" ref="N14668" type="pagenumber">75</cms:entry><cms:entry id="N1466C" part="chapter4" ref="N1466C" type="mm">586#458</cms:entry><cms:entry id="_Ref32148724" part="chapter4" ref="_Ref32148724" type="link"/><cms:entry id="_Ref32143126" part="chapter4" ref="_Ref32143126" type="link"/><cms:entry id="N1468B" part="chapter4" ref="N1468B" type="pagenumber">76</cms:entry><cms:entry id="N1468F" part="chapter4" ref="N1468F" type="mm">435#405</cms:entry><cms:entry id="_Ref32143663" part="chapter4" ref="_Ref32143663" type="link"/><cms:entry id="_Ref32143667" part="chapter4" ref="_Ref32143667" type="link"/><cms:entry id="N146B3" part="chapter4" ref="N146B3" type="table"/><cms:entry id="_Ref32146867" part="chapter4" ref="_Ref32146867" type="link"/><cms:entry id="N146BD" part="chapter4" ref="N146BD" type="pagenumber">77</cms:entry><cms:entry id="N14818" part="chapter4" ref="N14818" type="block">4.4.2.2</cms:entry><cms:entry id="N1481C" part="chapter4" ref="N1481C" type="pagenumber">78</cms:entry><cms:entry id="N14845" part="chapter4" ref="N14845" type="subsection">4.4.3</cms:entry><cms:entry id="_Ref32407049" part="chapter4" ref="_Ref32407049" type="link"/><cms:entry id="N1484D" part="chapter4" ref="N1484D" type="block">4.4.3.1</cms:entry><cms:entry id="N1486C" part="chapter4" ref="N1486C" type="pagenumber">79</cms:entry><cms:entry id="N14870" part="chapter4" ref="N14870" type="mm">600#307</cms:entry><cms:entry id="_Ref32147537" part="chapter4" ref="_Ref32147537" type="link"/><cms:entry id="N148A2" part="chapter4" ref="N148A2" type="pagenumber">80</cms:entry><cms:entry id="N148A6" part="chapter4" ref="N148A6" type="mm"/><cms:entry id="_Ref32496436" part="chapter4" ref="_Ref32496436" type="link"/><cms:entry id="N148B6" part="chapter4" ref="N148B6" type="pagenumber">81</cms:entry><cms:entry id="N148CD" part="chapter4" ref="N148CD" type="block">4.4.3.2</cms:entry><cms:entry id="N148E7" part="chapter4" ref="N148E7" type="pagenumber">82</cms:entry><cms:entry id="N148FA" part="chapter4" ref="N148FA" type="table"/><cms:entry id="_Ref32149650" part="chapter4" ref="_Ref32149650" type="link"/><cms:entry id="_Ref32497867" part="chapter4" ref="_Ref32497867" type="link"/><cms:entry id="N14C67" part="chapter4" ref="N14C67" type="pagenumber">83</cms:entry><cms:entry id="N14C6E" part="chapter4" ref="N14C6E" type="table"/><cms:entry id="_Ref32149673" part="chapter4" ref="_Ref32149673" type="link"/><cms:entry id="N14FD2" part="chapter4" ref="N14FD2" type="pagenumber">84</cms:entry><cms:entry id="N14FE9" part="chapter4" ref="N14FE9" type="mm"/><cms:entry id="_Ref32150141" part="chapter4" ref="_Ref32150141" type="link"/><cms:entry id="N15006" part="chapter4" ref="N15006" type="pagenumber">85</cms:entry><cms:entry id="N1500A" part="chapter4" ref="N1500A" type="mm"/><cms:entry id="_Ref32497632" part="chapter4" ref="_Ref32497632" type="link"/><cms:entry id="N1501D" part="chapter4" ref="N1501D" type="block">4.4.3.3</cms:entry><cms:entry id="N1502C" part="chapter4" ref="N1502C" type="pagenumber">86</cms:entry><cms:entry id="N15037" part="chapter4" ref="N15037" type="mm"/><cms:entry id="_Ref32208467" part="chapter4" ref="_Ref32208467" type="link"/><cms:entry id="N15052" part="chapter4" ref="N15052" type="block">4.4.3.4</cms:entry><cms:entry id="N15067" part="chapter4" ref="N15067" type="pagenumber">87</cms:entry><cms:entry id="N15075" part="chapter4" ref="N15075" type="section">4.5</cms:entry><cms:entry id="_Ref32499495" part="chapter4" ref="_Ref32499495" type="link"/><cms:entry id="_Ref32499504" part="chapter4" ref="_Ref32499504" type="link"/><cms:entry id="_Ref33253077" part="chapter4" ref="_Ref33253077" type="link"/><cms:entry id="N15097" part="chapter4" ref="N15097" type="pagenumber">88</cms:entry><cms:entry id="N150C5" part="chapter4" ref="N150C5" type="pagenumber">89</cms:entry><cms:entry id="N150CE" part="chapter4" ref="N150CE" type="section">4.6</cms:entry><cms:entry id="N150DB" part="chapter4" ref="N150DB" type="pagenumber">90</cms:entry><cms:entry id="chapter5" part="chapter5" ref="chapter5" type="chapter">5</cms:entry><cms:entry id="N150E6" part="chapter5" ref="N150E6" type="pagenumber">91</cms:entry><cms:entry id="N150F6" part="chapter5" ref="N150F6" type="pagenumber">92</cms:entry><cms:entry id="N15106" part="chapter5" ref="N15106" type="pagenumber">93</cms:entry><cms:entry id="N1511C" part="chapter5" ref="N1511C" type="pagenumber">94</cms:entry><cms:entry id="N1512E" part="chapter5" ref="N1512E" type="pagenumber">95</cms:entry><cms:entry id="N15135" part="chapter5" ref="N15135" type="pagenumber">96</cms:entry><cms:entry id="chapter6" part="chapter6" ref="chapter6" type="chapter">6</cms:entry><cms:entry id="N1513F" part="chapter6" ref="N1513F" type="pagenumber">97</cms:entry><cms:entry id="N15150" part="chapter6" ref="N15150" type="pagenumber">98</cms:entry><cms:entry ref="N1515B" type="back"/><cms:entry id="N1515D" part="N1515D" ref="N1515D" type="bibliography">
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id="_bib34" part="N1515D" ref="_bib34" type="citation"/><cms:entry id="_bib33" part="N1515D" ref="_bib33" type="citation"/><cms:entry id="_bib69" part="N1515D" ref="_bib69" type="citation"/><cms:entry id="_bib35" part="N1515D" ref="_bib35" type="citation"/><cms:entry id="_bib73" part="N1515D" ref="_bib73" type="citation"/><cms:entry ref="N15A97" type="abbreviation">
				Abbreviations</cms:entry><cms:entry ref="N15A9B" type="pagenumber">107</cms:entry><cms:entry ref="N15AA2" type="table"/><cms:entry id="N15C0D" part="N15C0D" ref="N15C0D" type="acknowledgement">
				Acknowledgments</cms:entry><cms:entry id="N15C11" part="N15C0D" ref="N15C11" type="pagenumber">108</cms:entry><cms:entry id="N15C27" part="N15C0D" ref="N15C27" type="pagenumber">109</cms:entry><cms:entry id="N15C33" part="N15C33" ref="N15C33" type="vita">
				Lebenslauf</cms:entry><cms:entry id="N15C37" part="N15C33" ref="N15C37" type="pagenumber">110</cms:entry><cms:entry id="N15C3E" part="N15C33" ref="N15C3E" type="table"/><cms:entry id="N15DA2" part="N15C33" ref="N15DA2" type="table"/><cms:entry id="N15DD2" part="N15DD2" ref="N15DD2" type="appendix">
				Publikationen</cms:entry><cms:entry id="N15DD4" part="N15DD2" ref="N15DD4" type="head"/><cms:entry id="N15DD6" part="N15DD2" ref="N15DD6" type="pagenumber">111</cms:entry><cms:entry id="N15DDB" part="N15DD2" ref="N15DDB" type="p"/><cms:entry id="N15DE1" part="N15DD2" ref="N15DE1" type="p"/><cms:entry id="N15DEF" part="N15DD2" ref="N15DEF" type="p"/><cms:entry id="N15DF8" part="N15DD2" ref="N15DF8" type="p"/><cms:entry id="N15DFE" part="N15DD2" ref="N15DFE" type="p"/><cms:entry id="N15E04" part="N15DD2" ref="N15E04" type="p"/><cms:entry id="N15E0A" part="N15DD2" ref="N15E0A" type="p"/><cms:entry id="N15E0D" part="N15DD2" ref="N15E0D" type="p"/><cms:entry id="N15E10" part="N15DD2" ref="N15E10" type="p"/><cms:entry id="N15E12" part="N15DD2" ref="N15E12" type="table"/><cms:entry id="N15E42" part="N15E42" ref="N15E42" type="declaration">
				Erklärung</cms:entry><cms:entry id="N15E46" part="N15E42" ref="N15E46" type="pagenumber">112</cms:entry><cms:entry part="N15A97" type=":current"/><cms:entry type=":lang">en</cms:entry><cms:entry id=":contents" part="front" ref=":contents" type=":contents">Table of contents</cms:entry><cms:entry type=":help"><url href="http://...">Help</url></cms:entry></cms:meta><cms:content><abbreviation id="N15A97">
			<head>
				<pagenumber id="N15A9B" label="107" numbering="arabic" start="107"/>Abbreviations</head>
			<p>
				<table frame="all" id="N15AA2" orient="port" tocentry="1">
					<tgroup align="left" char="" charoff="50" cols="2">
						<colspec colname="1" colnum="1"/>
						<colspec colname="2" colnum="2"/>
						<tbody valign="top">
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>ANN</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Artificial Neural Network</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>AUC</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Area Under Curve</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>CART</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Classification and Regression Trees</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>CTL</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Cytotoxic T-lymphocytes</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>ER</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Endoplasmic Reticulum</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>ERA(A)P</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>ER Aminopeptidase associated with Antigen Processing</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>HLA</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>human major histocompatibility complex</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>HPLC</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>High Performance Liquid Chromatography</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>MHC-I</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Major Histocompatibiliy Complex class I</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>MS</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Mass Spectrometry</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>PM</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Polynomial Method</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>ROC</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Receiver Operating Characteristics</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>SMM</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Stabilized Matrix Method</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>TAP</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>Transporter associated with Antigen Processing</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>T2</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>cell line containing constitutive proteasomes</p>
								</entry>
							</row>
							<row>
								<entry morerows="0" rotate="0" valign="top">
									<p>T2.27</p>
								</entry>
								<entry morerows="0" rotate="0" valign="top">
									<p>cell line containing immuno proteasomes</p>
								</entry>
							</row>
						</tbody>
					</tgroup>
				</table>
			</p>
		</abbreviation></cms:content></cms:document></cms:container>