1. Adams DH, Lloyd AR (1997), Chemokines:leucocyte recruitment and activation cytokines, Lancet 349: 490-495

2. Alm A (1992), Ocular Circulation, in Adler´s Physiology of the Eye: clinical application, ed. Hart Jr. WM, Mosby-Year-Book, Inc., St. Louis p 209-212

3. Avice MN, Sarfati M, Triebel F, Delespesse G, Demeure CE (1999), Lymphocyte activation gene-3, a MHC class II ligand expressed on activated T cells, stimulates TNF-alpha and IL-12 production by monocytes and dendritic cells., The Journal Of Immunology 162: 2748-2753

4. Baatz H, Pleyer U, Thiel HJ, Hammer C (1995), In vivo study of leukocyte-endothelium interaction in endotoxin-induced uveitis., Invest.Ophthalmol.Vis.Sci. 36: 1960-1967

5. Bartl R, Williams W (1997), Multiples Myelom, in Therapie-Handbuch, ed. Domschke W, Urban & Schwarzenberg, München

6. Batten P, Yacoub MH, Rose ML (1996), Effect of human cytokines (IFN-gamma, TNF-alpha, IL-1 beta, IL-4) on porcine endothelial cells: induction of MHC and adhesion molecules and functional significance of these changes., Immunology 87: 127-133

7. Baumheter S, Singer MS, Henzel W, Hemmerich S, Renz M, Rosen SD, Lasky LA (1993), Binding of L-selectin to the vascular sialomucin CD34., Science 262: 436-438

8. Becker MD, O´Rourke LM, Blackman WS, Planck SR, Rosenbaum JT (2000), Reduced leukocyte migration, but normal rolling and arrest, in interleukin-8 receptor momologue knockout mice, Invest.Ophthalmol.Vis.Sci. 41: 1812-1817

9. Bensley SH (1960), Microscopic Studies of the Living Iris, Anatomical record 138: 39-48

10. Berg EL, McEvoy LM, Berlin C, Bargatze RF, Butcher EC (1993), L-selectin-mediated lymphocyte rolling on MAdCAM-1, Nature 366: 695-698

11. Beutler B, Cerami A (1988), The common mediator of shock, cachexia, and tumor necrosis, Adv.Immunol. 42: 213-231

12. Biewenga J, van der Ende MB, Krist LF, Borst A, Ghufron M, van Rooijen N (1995), Macrophage depletion in the rat after intraperitoneal administration of liposome-encapsulated clodronate: depletion kinetics and accelerated repopulation of peritoneal and omental macrophages by administration of Freund's adjuvant, Cell Tissue Res. 280: 189-196

13. Bloch-Michel E, Nussenblatt RB (1987), International uveitis study group recommandations for the evaluation of intraocular inflammatory disease, Am.J.Ophthalmol. 103: 234-235

14. Bora NS, Woon MD, Tandhasetti MT, Cirrito TP, Kaplan HJ (1997), Induction of experimental autoimmune anterior uveitis by a self-antigen: melanin complex without adjuvant., Invest.Ophthalmol.Vis.Sci.38: 2171-2175

15. Bos HJ, van Bronswijk H, Helmerhorst TJ, Oe PL, Hoefsmit EC, Beelen RH (1988), Distinct subpopulations of elicited human macrophages in peritoneal dialysis patients and women undergoing laparoscopy: a study on peroxidatic activity., J.Leukoc.Biol. 43: 172-178

16. Breathnach SM (1988), The Langerhans cell., Br.J.Dermatol. 119: 463-469

17. Broekhuyse RM, Huitinga I, Kuhlmann ED, Rooijen NV, Winkens HJ (1997), Differential effect of macrophage depletion on two forms of experimental uveitis evoked by pigment epithelial membrane protein (EAPU), and by melanin-protein (EMIU)., Exp.Eye Res. 65: 841-848

18. Broekhuyse RM, Kuhlmann ED (1993), Experimental autoimmune anterior uveitis. The preparation of uveitogenic ocular melanin., Invest.Ophthalmol.Vis.Sci. 34: 698-700

19. Broekhuyse RM, Kuhlmann ED, Winkens HJ (1992), Experimental autoimmune anterior uveitis (EAAU). II. Dose-dependent induction and adoptive transfer using a melanin-bound antigen of the retinal pigment epithelium., Exp.Eye Res. 55: 401-411

20. Broekhuyse RM, Kuhlmann ED, Winkens HJ (1993a), Experimental autoimmune anterior uveitis (EAAU). III. Induction by immunization with purified uveal and skin melanins., Exp.Eye Res. 56: 575-583

21. Broekhuyse RM, Kuhlmann ED, Winkens HJ (1993b), Experimental autoimmune anterior uveitis (EAAU): induction by melanin antigen and suppression by various treatments., Pigment Cell Res. 6: 1-6

22. Broekhuyse RM, Kuhlmann ED, Winkens HJ (1996), Experimental melanin-protein induced uveitis (EMIU) is the sole type of uveitis evoked by a diversity of ocular melanin preparations and melanin-derived soluble polypeptides., Jpn.J.Ophthalmol. 40: 459-468

23. Broekhuyse RM, Kuhlmann ED, Winkens HJ, van Vugt AH (1991), Experimental autoimmune anterior uveitis (EAAU), a new form of experimental uveitis. I. Induction by a detergent-insoluble, intrinsic protein fraction of the retinal pigment epithelium., Exp.Eye Res. 52: 465-474

24. Broekhuyse RM, Winkens HJ, Kuhlmann ED (1995), Multiple recurrences in melanin-protein-induced uveitis in the rat, Ocular Immunology and Inflammation 3: 149-155

25. Butler TL, McMenamin PG (1996), Resident and infiltrating immune cells in the uveal tract in the early and late stages of experimental autoimmune uveoretinitis, Invest.Ophthalmol.Vis.Sci. 37: 2195-2210

26. Calder VL, Prickett TC, McKenzie JL, Hart DN (1993), Analysis of cytokine and cytokine receptor production by human dendritic cells., Adv.Exp.Med.Biol. 329: 81-85

27. Carlos TM, Harlan JM (1994), Leukocyte-endothelial adhesion molecules., Blood 84: 2068-2101

28. Caspi RR (1999), Immune mechanisms in uveitis, Springer Semin.Immunopathol. 21: 113-124

29. Castenholz A (1966), [Vital microscopic studies of the anterior bulbus section of small albino rodents. Basis of methods and description of apparatus arrangement], Z.Wiss.Mikrosk. 67: 78-91

30. Chan CC, Hikita N, Dastgheib K, Whitcup SM, Gery I, Nussenblatt RB (1994), Experimental melanin-protein-induced uveitis in the Lewis rat. Immunopathologic processes, Ophthalmology. 101: 1275-1280

31. Chan CC, Li Y, Sun B, Li Q, Matteson DM, Shen DF, Nussenblatt RB, Zhai Y (1998), Recombinant adenovirus encoding gp100 modulates experimental melanin-protein induced uveitis (EMIU)., J.Autoimmun. 11: 111-118

32. Claassen I, van Rooijen N, Claassen E (1990), A new method for removal of mononuclear phagocytes from heterogenous cell populations in vitro, using the liposome-mediated macrophage "suicide" technique, J.Immunol.Methods 134: 153-161

33. Collins RC (1949), Experimental studies on sympathetic ophthalmia., Am.J.Ophthalmol. 32: 1687-1699

34. Csaky K, Nussenblatt RB (1999), Gene therapy in the treatment of ocular inflammation, Springer Semin.Immunopathol. 21: 191-197

35. D'Ambrosio D, Panina BP, Rogge L, Sinigaglia F (1999), Molecular mechanisms of T helper cell differentiation and tissue-specific migration., Curr.Top.Microbiol.Immunol. 246: 117-122

36. Darrell RW, Wagener HP, Kurland LT (1962), Epidemiology of uveitis, incidence and prevalence in a small urban community, Arch.Ophthalmol. 68: 502

37. de-Saint VB, Fugier VI, Massacrier C, Gaillard C, Vanbervliet B, Ait YS, Banchereau J, Liu YJ, Lebecque S, Caux C (1998), The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation., The Journal Of Immunology 160: 1666-1676

38. de Waal MR, Haanen J, Spits H, Roncarolo MG, Te Velde A, Figdor C, Johnson K, Kastelein R, Yssel H, de Vries J (1991), IL-10 and viral IL-10 strongly reduce antigen specific human T cells proliferation by demishing the antigen presenting capacity of monocytes via downregulation of class II MHC expression, J.Exp.Med. 174: 915-924

39. Delemarre FG, Kors N, van Rooijen N (1990), Elimination of spleen and of lymph node macrophages and its difference in the effect on the immune response to particulate antigens., Immunobiology 182: 70-78

40. Demeure CE, Tanaka H, Mateo V, Rubio M, Delespesse G, Sarfati M (2000), CD47 engagement inhibits cytokine production and maturation of human dendritic cells., The Journal Of Immunology 164: 2193-2199

41. Dick AD, McMenamin PG, Korner H, Scallon BJ, Ghrayeb J, Forrester JV, Sedgwick JD (1996), Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina., Eur.J.Immunol. 26: 1018-1025

42. Dijkstra CD, Dopp EA, Huitinga I, Damoiseaux JG (1992), Macrophages in experimental autoimmune diseases in the rat: a review, Curr.Eye Res. 11 Suppl: 75-79

43. Dijkstra CD, Döpp EA, Joling P, Kraal G (1985), The heterogenicity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3., Immunology 54: 589-599

44. Dinarello CA (1989a), Interleukin-1 and its biologically related cytokines, Adv.Immunol. 44: 153-205

45. Dinarello CA, Orencole SF, Savage N (1989b), Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors., Adv.Exp.Med.Biol. 254: 45-53

46. Doukas J, Pober JS (1990), Lymphocyte-mediated activation of cultured endothelial cells (EC). CD4+ T cells inhibit EC class II MHC expression despite secreting IFN-gamma and increasing EC class I MHC and intercellular adhesion molecule-1 expression., The Journal Of Immunology 145: 1088-1098

47. Elschnig A (1910), Studien zur sympathischen Ophthalmie. II. Die antigene Wirkung des Augenpigments., Graefes.Arch.Clin.Exp.Ophthalmol. 76:509:

48. Fausto N (1991), Multifunctional roles of transforming growth factor-β1, Lab.Invest. 65: 497-499

49. Feldmann M, Charles P, Taylor P, Maini RN (1998), Biological insights from clinical trials with anti-TNF therapy., Springer Semin Immunopathol 20: 211-228

50. Fernandez-Botran R, Sanders VM, Mosmann TR, Vitetta ES (1988), Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells, J.Exp.Med. 168: 543-558

51. Fidler IJ (1977), Depression of macrophages in mice drinking hyperchlorinated water, Nature 270: 735

52. Fleisch H (1988), Biphosphonates: a new class of drugs in diseases of bone and calcium metabolism, in Handbook Exp. Pharmacol., ed. Baker P, Springer Verlag, Heidelberg p 441-466

53. Fleisch H (1997), Biphosphonates in Bone Disease, New York

54. Fleisher LN, Ferrell JB, McGahan MC (1990), Ocular inflammatory effects of intravitreally injected tumor necrosis factor-alpha and endotoxin., Inflammation 14: 325-335

55. Forrester JV, Liversidge J, Dua HS, Towler H, McMenamin PG (1990), Comparison of clinical and experimental uveitis, Curr.Eye Res. 9 Suppl: 75-84

56. Forrester JV, McMenamin PG, Liversidge J, Lumsden L (1993), Dendritic cells and "dendritic" macrophages in the uveal tract, Adv.Exp.Med.Biol. 329: 599-604

57. Funk RHW, Apple DJ, Naumann GOH (1997), Embryologie, Anatomie und Untersuchungstechniken, in Pathologie des Auges - Bd.1, ed. Naumann GOH, Springer, Berlin, Heidelberg, New York p 1-79

58. Geissler K, Harrington M, Srivastava C, Leemhuis T, Tricot G, Broxmeyer HG (1989), Effects of recombinant human colony stimulating factors (CSF) (granulocyte-macrophage CSF, granulocyte CSF, and CSF-1) on human monocyte/macrophage differentiation, The Journal Of Immunology 143: 140-146

59. Gessani S, Belardelli F (1998), IFN-γ Expression in Macrophages and its Possible Biological Significance, Cytokine.Growth Factor.Rev. 9: 117-123

60. Hammer RE, Maika SD, Richardson JA, Tang J-P, Taurog JD (1990), Spontaneous inflammatory desease in transgenic rats expressing expressing HLA-B27 and human beta-2 microglobulin: an animal model of HLA-B27-associated human disorders., Cell 63: 1099

61. Harlan JM (1985), Leukocyte-endothelial interactions., Blood 65: 513-525

62. Hart DN, Prickett TC (1993a), Adhesion molecules in tonsil DC-T cell interactions., Adv.Exp.Med.Biol. 329: 65-69

63. Hart DN, Prickett TC (1993b), Intercellular adhesion molecule-2 (ICAM-2) expression on human dentritic cells., Cell Immunol. 148: 447-454

64. Havenith CE, Breedijk AJ, Hoefsmit EC (1992), Effect of Bacillus Calmette-Guerin inoculation on numbers of dendritic cells in bronchoalveolar lavages of rats., Immunobiology 184: 336-347

65. Huitinga I, Damoiseaux JG, van Rooijen N, Dopp EA, Dijkstra CD (1992), Liposome mediated affection of monocytes, Immunobiology 185: 11-19

66. Huitinga I, Ruuls SR, Jung S, van Rooijen N, Hartung HP, Dijkstra CD (1995), Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats, Clin.Exp.Immunol. 100: 344-351

67. Hurst M, Noble S (1999), Clodronate: a review of its use in breast cancer., Drugs Aging 15: 143-167

68. Illig L, Conraths H (1958), Mikroskopische Lebendaufnahmen vom Kapillarbett des Tieres und des Menschen. Normale und pathologische Bilder von den kleinsten Blutgefäßen des Säugetier Mesenteriums, Boehringer, Ingelheim,

69. Issazadeh S, Ljundahl A, Hojeberg B, Mustafa M, Olsson T (1995), Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β, J.Neuroimmunol. 154: 205-212

70. Jaffe GJ, Yang C-S, Want X-C, Cousins SW, Gallemore RP, Ashton P (1998), Intravitreal sustained-release cyclosporin in the treatment of experimental uveitis, Ophthalmology. 105: 46

71. Jung S, Huitinga I, Schmidt B, Zielasek J, Dijkstra CD, Toyka KV, Hartung HP (1993), Selective elimination of macrophages by dichlormethylene diphosphonate-containing liposomes suppresses experimental autoimmune neuritis, J.Neurol.Sci. 119: 195-202

72. Keller R (1990), Mechanism of macrophage-mediated tumor cell killing: a comparative analysis of the role of reactive nitrogen intermediates and TNF, Int.J.Cancer 46: 682-695

73. Kim MC, Bora NS, Kabeer NH, Kaplan HJ (1994), Sequential expression of ICAM-1, LFA-1, MHC-II molecules in the pathogenesis of experimental allergic iritis (EAI), in Advances in Ocular Immunology, ed. Nussenblatt RB, Whitcup SM, Caspi RR, and Gery I, Elsevier, p 95-98

74. Kim MC, Kabeer NH, Tandhasetti MT, Kaplan HJ, Bora NS (1995), Immunohistochemical studies on melanin associated antigen (MAA) induced experimental autoimmune anterior uveitis (EAAU)., Curr.Eye Res. 14: 703-710

75. Konstantopoulos K, McIntire LV (1997), Effects of fluid dynamic forces on vascular cell adhesion., J.Clin.Invest. 100: S19-S23

76. Küchle M, Naumann GOH (1997), Intraokulare Entzündungen, in Pathologie des Auges - Bd.1, ed. Naumann GOH, Springer, Berlin, Heidelberg, New York p 143-267

77. Larsen CG, Anderson AO, Apella AE, Oppenheim JJ, Matsushima K (1989), The neutrophil activating protein (NAP-1) is also chemotactic for T-lymphocytes, Science 243: 1464-1466

78. Lasky LA, Singer MS, Dowbenko D, Imai Y, Henzel W, Fennie C, Watson S, Rosen SD (1992), Glycosylation-dependent cell adhesion molecule 1: a novel mucin-like adhesion ligand for L-selectin., Cold Spring Harb.Symp. 57: 259-269

79. Lawrence MB, Springer TA (1991), Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins., Cell 65: 859-873

80. Le J, Vilcek J (1989), Interleukin 6: a multifunctional cytokine regulating immune reaction and the acute phase protein response, Lab.Invest. 61: 588-602

81. Ley K, Gaehtgens P, Fennie C, Singer MS, Lasky LA, Rosen SD (1991), Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo., Blood 77: 2553-2555

82. Malhotra R, Taylor NR, Bird MI (1996), Anionic phospholipids bind to L-selectin (but not E-selectin) at a site distinct from the carbohydrate-binding site, Biochem.J. 314 ( Pt 1): 297-303

83. Martenet AC (1966), [Experimental herpetic uveitis. Thoughts on a model]
Uveite herpetique experimentale. Reflexions sur un modele., Ophthalmologica 152: 283-290

84. Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD (1993), Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice, Cell 74: 541-554

85. Mayrovitz HN (1992), Leukocyte rolling: A prominent feature of venules in intact skin of anesthetized hairless mice., The American Physiological Society 262: H157-H161

86. McAllister CG, Vistica BP, Sekura R, Kuwabara T, Gery I (1986), The effects of pertussis toxin on the induction and transfer of experimental autoimmune uveoretinitis., Clin.Immunol.Immunopathol 39: 329-336

87. McMenamin C, Broekhuyse RM, Forrester JV (1993a), Ultrastructural pathology of experimental autoimmune uveitis: A Review, Micron 24: 521-546

88. McMenamin PG (1997a), The distribution of immune cells in the uveal tract of the normal eye, Eye 11: 183-193

89. McMenamin PG (1999), Dendritic cells and macrophages in the uveal tract of the normal mouse eye, Br.J.Ophthalmol. 83: 598-604

90. McMenamin PG, Crewe J, Kijlstra A (1997b), Resident and infiltrating cells in the rat iris during the early stages of experimental melanin protein-induced uveitis (EMIU)., Ocul.Immunol.Inflamm. 5: 223-233

91. McMenamin PG, Crewe J, Morrison S, Holt PG (1994), Immunomorphologic studies of macrophages and MHC class II-positive dendritic cells in the iris and ciliary body of the rat, mouse, and human eye., Invest.Ophthalmol.Vis.Sci. 35: 3234-3250

92. McMenamin PG, Forrester JV, Steptoe R, Dua HS (1993b), Ultrastructural pathology of experimental autoimmune uveitis in the rat, Autoimmunity. 16: 83-93

93. McMenamin PG, Holthouse I, Holt PG (1992), Class II major histocompatibility complex (Ia) antigen-bearing dendritic cells within the iris and ciliary body of the rat eye: distribution, phenotype and relation to retinal microglia., Immunology 77: 385-393

94. Menger MD, Lehr HA (1993), Scope and perspectives of intravital microscopy--bridge over from in vitro to in vivo., Immunology Today 14: 519-522

95. Moore KL, Stults NL, Diaz S, Smith DF, Cummings RD, Varki A, McEver RP (1992), Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells., J.Cell Biol. 118: 445-456

96. Mosmann TR, Coffman RL (1989), TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties, Annu.Rev.Immunol. 7: 145-173

97. Mönkkönen J, Heath TD (1993), The effect of liposome-encapsulated and free clodronate on the growth of macrophage like cells in vitro: The role of calcium and iron, Calcif.Tissue Int. 53: 139

98. Munoz JJ (1988), Action of pertussigen (pertussis toxin) on the host immune system, in Pathogenesis and Immunity in Pertussis, ed. Wardlaw AC and Parton R, John Wiley & Sons, London p 173-192

99. Nakamura S, Yamakawa T, Sugita M, Kijima M, Ishioka M, Tanaka S, Ohno S (1994), The role of tumor necrosis factor-alpha in the induction of experimental autoimmune uveoretinitis in mice, Invest.Ophthalmol.Vis.Sci. 35: 3884-3889

100. Nathan CF, Murray HW, Wiebe ME, Rubin BY (1983), Identification of interferon-g as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity, J.Exp.Med. 158: 670-689

101. Nussenblatt RB, Caspi RR, Mahdi RM (1990), Inhibition of S-antigen induced experimental autoimmune uveoretinitis by oral induction of tolerance with S-antigen, The Journal Of Immunology 144: 1689

102. Paleolog EM, Aluri GR, Feldmann M (1992), Contrasting effects of interferon gamma and interleukin 4 on responses of human vascular endothelial cells to tumour necrosis factor alpha., Cytokine. 4: 470-478

103. Paliard X, de Waal MR, Yssel H, Blanchard D, Chretien I, Abrams J, de VJ, Spits H (1988), Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones., The Journal Of Immunology 141: 849-855

104. Pavan LD (1968), Mycoplasma in the etiology of anterior and posterior uveitis: an experimental model., Arch.Ophthalmol. 80: 416

105. Pelger RC, Hamdy NA, Zwinderman AH, Lycklama, Papapoulos SE (1998), Effects of the bisphosphonate olpadronate in patients with carcinoma of the prostate metastatic to the skeleton., Bone 22: 403-408

106. Pelorgeas S, Martin JB, Satre M (1992), Cytotoxicity of dichlormethane diphosphonate and of 1-hydroxyethane-1,1-diphosphonate in the amoebae of the slime mould Dictyostelium discoideum, Biochem.Pharmacol. 44: 2157

107. Pierce GF, Mustoe TA, Lingelbach J, Masakowski VR, Griffin GL, Senior RM, Deuel TF (1989), Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms., J.Cell Biol. 109: 429-440

108. Planck SR, Huang XN, Robertson JE, Rosenbaum JT (1994), Cytokine mRNA levels in rat ocular tissues after systemic endotoxin treatment, Invest.Ophthalmol.Vis.Sci. 35: 924-930

109. Plasman N, Vray B (1993), Mouse peritoneal macrophages: characterization of functional subsets following Percoll density gradients., Res.Immunol. 144: 151-163

110. Pouvreau I, Zech JC, Thillaye GB, Naud MC, van RN, de KY (1998), Effect of macrophage depletion by liposomes containing dichloromethylene-diphosphonate on endotoxin-induced uveitis, J.Neuroimmunol.86: 171-181

111. Qian Q, Jutila MA, van RN, Cutler JE (1994), Elimination of mouse splenic macrophages correlates with increased susceptibility to experimental disseminated candidiasis, The Journal Of Immunology 152: 5000-5008

112. Rogers MJ, Russel RG, Blackburn GM, Williamson MP, Watts DJ (1992), Metabolism of halogenated bisphosphonates by the cellular slime mould Dictyostelium discoideum, Biochem.Biophys.Res.Commun. 189: 414-423

113. Rosenbaum JT, Howes-EL J, Rubin RM, Samples JR (1988), Ocular inflammatory effects of intravitreally-injected tumor necrosis factor., American Journal of Pathology 133: 47-53

114. Rosenbaum JT, McDevitt HO, Guss RB, Egbert PR (1980), Endotoxin-induced uveitis in rats as a model for human disease., Nature 286: 611-613

115. Rummelt V, Naumann GOH (1997), Uvea, in Pathologie des Auges - Bd.1, ed. Naumann GOH, Springer, Berlin, Heidelberg, New York p 693-844

116. Saito T, Yamaguchi J (1985), 2-Chloroadenosine: A selective lethal effect to mouse macrophages and its mechanism, The Journal Of Immunology 134: 1815

117. Salkowski CA, Neta R, Wynn TA, Strassmann G, van RN, Vogel SN (1995), Effect of liposome-mediated macrophage depletion on LPS-induced cytokine gene expression and radioprotection, The Journal Of Immunology 155: 3168-3179

118. Samples JR, Boney RS, Rosenbaum JT (1993), Ocular iinflammatory effects of intravitreally injected interleukin-2, Curr.Eye Res. 12: 649-654

119. Schmidt-Weber CB, Rittig M, Buchner E, Hauser I, Schmidt I, Palombo KE, Emmrich F, Kinne RW (1996), Apoptotic cell death in activated monocytes following incorporation of clodronate-liposomes, J.Leukoc.Biol. 60: 230-244

120. Shane E, Rodino MA, McMahon DJ, Addesso V, Staron RB, Seibel MJ, Mancini D, Michler RE, Lo SH (1998), Prevention of bone loss after heart transplantation with antiresorptive therapy: a pilot study., J.Heart Lung Transplant. 17: 1089-1096

121. Shimotsuma M, Takahashi T, Kawata M, Dux K (1991), Cellular subsets of the milky spots in the human greater omentum., Cell Tissue Res. 264: 599-601

122. Smit RLMJ, Baarsma GS, de Vries J (1993), Classification of 750 consecutive uveitis patients in the Rotterdam Eye Hospital, Int.Ophthalmol. 71-75

123. Soesatyo M, Biewenga J, van Rooijen N, Kors N, Sminia T (1991), The in situ immune response of the rat after intraperitoneal depletion of makrophages by liposome-encapsulated dichlormethylen diphosphonate, Res.Immunol. 142: 533-540

124. Springer TA (1994), Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm, Cell 76: 301-314

125. Steptoe RJ, Holt PG, McMenamin PG (1995), Functional studies of major histocompatibility class II-positive dendritic cells and resident tissue macrophages isolated from the rat iris, Immunology 85: 630-637

126. Suttorp SM, Rothova A (1996), The possible impact of uveitis in blindness: a literature survey., Br.J.Ophthalmol. 80: 844-848

127. Thepen T, van Rooijen N, Kraal G (1990), Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice, J.Exp.Med. 170: 499-509

128. Torres PF, Slegers TPAM, Peek R, van Rooijen N, van der Gaag R, Kijlstra A, De Vos AF (1999), Changes in cytokine mRNA levels in experimental corneal allografts after local clodronat-liposome treatment, Invest.Ophthalmol.Vis.Sci. 40: 3194-3201

129. Trentham DE, Dynesius-Trentham RA, Orav EJ (1993), Effect of oral administration of type II collagen on rheumatoid arhtritis, Science 261: 1727

130. Unanue ER (1984), Antigen-presenting function of the macrophage, Annu.Rev.Immunol. 2: 395-428

131. Unanue ER, Allen PM (1987), The basis of immunomodulatory role of macrophages and other accessory cells, Science 236: 551-557

132. Vadot E (1992), Epidemiology of intermediate uveitis: a prospective study in Savoy, Dev.Ophthalmol. 23: 33-34

133. van de Loosdrecht AA, Beelen RH, Ossenkoppele GJ, Broekhoven MG, Langenhuysen MMAC (1993), Cellular and cytotoxic dependent monocyte mediated leukemic cell death: modulation by IFN and TNF, Exp.Hematol. 21: 461-468

134. van de Loosdrecht AA, Ossenkoppele GJ, Beelen RHJ, Langenhuysen MMAC (1992), Monocyte mediated cytotoxicity against a human histiocytic lymphoma cell line. Role of interferon-δand tumor necrosis factor-α, Cancer Immunol.Immunother. 34: 393-398

135. van der Veen G, Broersma L, Dijkstra CD, van Rooijen N, van Rij G, van der Gaag R (1994), Prevention of corneal allograft rejection in rats treated with subconjunctival injections of liposomes containing dichloromethylene diphosphonate., Invest.Ophthalmol.Vis.Sci. 35: 3505-3515

136. Van Geldern RN, Kaplan HJ (1999), Immunosuppression in uveitis therapy, Springer Semin.Immunopathol. 21: 179-190

137. van Lent PLEM, van den Bersselaar LAM, Holthuyzen AEM, van Rooijen N, van de Putte LBA, van den Berg WB (1994), Phagozytic synovial lining cells in experimentally induced chronic arthritis: down-regulation of synovitis by Cl₂MDP-liposomes, Scand.J.Rheumatol. 23: 83-89

138. van Rooijen N (1989a), The liposome-mediated macrophage 'suicide' technique, J.Immunol.Methods 124: 1-6

139. van Rooijen N (1992), Liposomes as an in vivo tool to study and manipulate macrophage function, Res.Immunol. 143: 177-178

140. van Rooijen N (1993), Extracellular and intracellular action of clodronate in osteolytic bone disease? A hypothesis, Calcif.Tissue Int. 52: 407

141. van Rooijen N, Kors N, Ende M, Dijkstra CD (1990), Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate, Cell Tissue Res. 260: 215-222

142. van Rooijen N, Kors N, Kraal G (1989b), Macrophage subset repopulation in the spleen: differential kinetics after liposome-mediated elimination, J.Leukoc.Biol. 45: 97-104

143. van Rooijen N, Poppema A (1992), Efficacy of various water-soluble chelator molecules in the liposome-mediated macrophage "suicide" techique, J.Pharmacol.Toxicol.Methods 28: 217

144. van Rooijen N, Sanders A (1994), Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications, J.Immunol.Methods 174: 83-93

145. Vezzio N, Sarfati M, Yang LP, Demeure CE, Delespesse G (1996), Human Th2-like cell clones induce IL-12 production by dendritic cells and may express several cytokine profiles., Int.Immunol. 8: 1963-1970

146. Villaroya H, Violleau K, Ben Younes-Chennoufi A, Baumann N (1996), Myelin-induced experimental allergic encephalomyelitis in Lewis rats: tumor necrosis factor a levels in serum and cerebrospinal fluid - Immunohistochemical expression in glial cells and macrophages of optic nerve and spinal cord, J.Neuroimmunol. 64: 55-61

147. von Andrian UH, Berger EM, Ramezani L, Chambers JD, Ochs HD, Harlan JM, Paulson JC, Etzioni A, Arfors KE (1993), In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes., J.Clin.Invest. 91: 2893-2897

148. Wakefield D, Cuello C, Di Girolamo N, Lloyd A (1999), The Role of Cytokines and Chemokines in Uveitis, Dev.Ophthalmol. 31: 53-66

149. Weiner HL, Mackin GA, Matsui (1993), Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis, Science 259: 1321

150. Weiss JM, Downie SA, Lyman WD, Berman JW (1998), Astrocyte-derived monocyte-chemoattractant protein-1 directs the transmigration of leukocytes across a model of the human blood-brain barrier., The Journal Of Immunology 161: 6896-6903

151. Whitcup SM, Kozhich AT, Lobanoff M, Wolitzky BA, Chan CC (1997), Blocking both E-selectin and P-selectin inhibits endotoxin-induced leukocyte infiltration into the eye., Clin.Immunol.Immunopathol. 83: 45-52

152. Wijffels JF, Hendrickx RJ, Steenbergen JJ, Eestermans IL, Beelen RH (1992), Milky spots in the mouse omentum may play an important role in the origin of peritoneal macrophages., Res.Immunol. 143: 401-409

153. Wildner G, Thurau SR (1994), Cross-reactivity between an HLA-B27-derived peptide and a retinal autoantigen peptide: a clue to major histocombatibility complex association autoimmune disease, Eur.J.Immunol. 24: 2579-2585

154. Woon MD, Kaplan HJ, Bora NS (1998), Kinetics of cytokine production in experimental autoimmune anterior uveitis (EAAU)., Curr.Eye Res. 17: 955-961

155. Woon MD, Kaplan HJ, Bora NS. 22kD Protein Associated With Bovine Iris/Ciliary Body Melanin Causes Experimental Anterior Uveitis. ARVO Abstract Book , S142. 1999.

156. Yokota K, Ariizumi K, Kitajima T, Bergstresser PR, Street NE, Takashima A (1996), Cytokine-mediated communication between dendritic epidermal T cells and Langerhans cells. In vitro studies using cell lines., The Journal Of Immunology 157: 1529-1537

157. Yoshida M, Yoshimura N, Hangai M, Tanihara H, Honda Y (1994), Interleukin-1 alpha, interleukin-1 beta, and tumor necrosis factor gene expression in endotoxin-induced uveitis., Invest.Ophthalmol.Vis.Sci. 35: 1107-1113