Ryseck, Ilona: Modulation von Proliferation und Migration boviner kornealer Endothelzellen in Kultur durch humanes Kammerwasser, Transforming Growth Factor-Beta 2 und Ascorbinsäure

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Literaturverzeichnis

1. Allen J.B., McGahan M.C., Ogawa Y., Sellon D.C., Clark B.D. und Fleisher L.N. (1996 "): Intravitreal transforming growth factor-ß2 decreases cellular infiltration in endotoxin-induced ocular inflammation in rabbits" . Curr Eye Res 15 : 95-103

2. Allen J.B., Davidson M.G., Nasisse M.P., Fleisher L.N. und McGahan M.C. (1998 ): "The lens influences aqueous humor levels of transformimg growth factor-ß2. " Graefes Arch Clin Exp Ophthalmol 236 : 305-311

3. Assoian R.K., Komoriya A., Meyers C.A., Miller D.M. und Sporn M.B . (1983 ): "Transforming growth factor beta in human platelets." J Biol Chem 258 :7155-7160

4. Baird A., Böhlen P., Ling N. und Guillemin R. (1985 ) "Radioimmunoessay for fibroblast growth factor(FGF): release by the bovine anterior pituitary in vitro" . Regul Pept 10 :309-317

5. Baird A. und Böhlen P .: "Fibroblast Growth factor" in Sporn M.B. und Roberts A.B.(Hrsg .): Peptide Growth factors and their receptors. Berlin, Heidelberg, New York, London, Paris, Tokyo, Hong Kong 1990 , S. 369-418

6. Barnes D. und Sato G. (1980 ): "Serum cell culture: an unifying approach" . Cell 22 : 649

7. Benade L., Howard T. und Burk D. (1964 ): "Synergistic killing of Ehrlich ascitis carcinoma cells by ascorbate and 3-amino-1,2,4-triazole" . Oncology 23 : 33-43

8. Bernadinis E., Tieri O., Polzella A. und Iuglio N. (1965 ): "The chemical composition of the human aqueous humor in normal and pathological conditions" . Exp Eye Res 4 : 179-186

9. Bianchi J und Rose R.C. (1986 ): "Dehydroascorbic acid and cell membranes: Possible disruptive effects." Toxicology 40 : 75

10. Bigley R., Wirth M., Layman D., Riddle M. und Stankova L. (1983 "): Interaction between glucose and dehydroascorbate transport in human neutrophils and fibroblasts" . Diabetes 32 : 545

11. Bode A.M., Vanderpool S.S., Carlson E.C., Meyer D.A. und Rose R.C. (1991 ): "Ascorbic acid uptake and metabolism by corneal endothelium" . Invest Ophthalmol Vis Sci 32 : 2266-2271

12. Bradshaw R.A. und Cavanaugh K.P .: "Isolation and Characterization of Growth Factors" , in Roberts A.B., und Sporn M.B. (Hrsg.): Peptide Growth Factors and their Receptors I . Berlin, Heidelberg, New York, London, Paris, Tokyo, Hong Kong 1990 , S.17-36

13. Burke J., Foster S. und Herschler J . (1982/83 ): "Aqeous humor as a modulator of growth in fibroblast cultures." Curr Eye Res 2 : 835-841

14. Capella J.A . (1972 ): "Regeneration of endothelium in diseased and injured corneas" . Am J Ophthalmol 74 : 811-817

15. Chan C.C., Duhamel L. und Ford-Hutchinson A. (1985 ): "Leukotriene B4 and 12-hydroxyeicosatetraenoic acid stimulate epidermal proliferation in vivo in the guinea pig" . J Invest Dermatol 85 : 333-334

16. Cheifetz S., Weatherbee J.A. und Tsang M.L.S. (1987 ): "The Transforming growth factor ß-system, a complex pattern of crossreactive ligands and receptors" . Cell 48 : 409-415

17. Cohen S. (1962 "): Isolation of a mouse submaxillary gland protein accelerating incisor eruptionand eyelid opening in the newborn animal." J Biol Chem 237 :1555-1562

18. Coulter J.B., Engelke J.A. und Eaton D.K. (1980 ): "Insulin concentrations in aqueous humor after paracentesis and feeding of rabbits." Invest Ophthalmol Vis Sci 19 : 1524


68

19. de Martin R., Haendler B., Hofer-Warbinek R., Gaugitsch H., Wrann M., Schlusener H., Seifert J.M., Bodmer S., Fontana A. und Hofer E. (1987 ): "Complementary DNA for human glioblastoma-derived T cell surpressor factor, a novel member of the transforming growth factor beta gene family" . EMBO J 6 :3673-3677

20. Derynck R., Jarrett J.A., Chen E.Y., Eaton D.H., Bell J.R., Assoian R.K., Roberts A.B., Sporn M.B. und Goeddel D.V. (1985 ): "Human Transforming growth factor beta cDNA sequence and expression in tumor cell lines" . Nature 316 :701-705

21. Derynck R., Lindquist P.B., Lee A., Wen D., Tamm J., Graycar J.L., Rhee L., Mason A.J., Miller D.A., Coffey R.J., Moses H.L. und Chen E.Y. (1988 "): A new type of transforming growth factor ß, TGF-ß3" . EMBO J 7 :3737-3743

22. Derynck R. (1996 ): "Nomenclature: vertebrate mediators of TGFß family signals" . Cell 87 : 173

23. Eakins K.E., Whitelocke R.A.F., Perkins E.S., Bennet A. und Unger W.G. (1972 ): "Release of prostaglandins in ocular inflammation in the rabbit." Nature (New Biol) 239 : 248

24. Esch F., Baird A., Ling N., Ueno N., Hill F., Denoroy L., Klepper R., Gospodarowicz D., Böhlen P. und Guillemin R. (1985 ): "Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine acidic FGF" . Proc Natl Acad Sci USA 82 :6507-6511

25. Friedrich W. : Handbuch der Vitamine. München , Wien, Baltimore 1987

26. Geroski D.H. und Edelhauser H.F. ": Functional response to wounding in the corneal endothelium" . in Beuerman R.W., Crosson C.E., Kaufman H.E. (Hrsg.): Healing processes in the cornea , 1989 , S. 111-125

27. Gospodarowicz D., Meschner A. und Birdwell C.R. (1977 ): "Stimulation of corneal endothelial cell proliferation in vitro by fibroblast and epidermal growth factors" . Exp. Eye Res 25 :75-89

28. Granstein R.D., Staszewski R., Knisely T.L., Zeira E., Nazareno R., Latina M. und Albert D.M. (1990 ): "Aqueous humor contains Transforming Growth Factor-ß and a small( <3500 Daltons) inhibitor of thymocyte proliferation." J Immunol 144 : 3021-3027

29. Gregory H. (1975 ): "Isolation and Structure of urogastrone and its relationship to epidermal growth factor" , Nature 257 :325-327

30. Grehn F. und Leydecker W. : Erkrankungen der Hornhaut. in Grehn F. und Leydecker W. : Augenheilkunde, Berlin, Heidelberg, New York 1995 , S. 77-107

31. Gupta A.G., Hirakata A. und Proia A.D. (1993 ): "Effect of Inhibitors of Arachidonic Acid Metabolism on Corneal Reepithelialization in the Rat" . Exp Eye Res 56 : 701-708

32. Hartmann Ch., Kilp H. und Kolp M. (1986 "): Die Regeneration des menschlichen Hornhautendothels nach direktem Nd:YAG-Lasertrauma" . Fortschr Ophthalmol 83 :448-452

33. Heath H. und Fiddick R. (1966 ): "The active transport of ascorbic acid by the rat retina" . Exp Eye Res 5 : 156

34. Heimark R.L., Twardzik D.R. und Schwartz S.M. (1986 ): "Inhibition of endothelial regeneration by type-beta transforming growth factor from platelets" . Science 233 : 1078-1080

35. Helbig H., Korbmacher C. und Wiederholt M. (1990 ): "Mechanismen des Transportes von Ascorbinsäure in das Kammerwasser." Fortschr Ophthalmol 87 : 421-424

36. Helbig H., Kittredge K.L., Coca-Prados M., Davis J., Palestine A.G. und Nussenblatt R.B. (1991 ): "Mammalian ciliary-body epithelial cells in culture produce transforming growth factor-beta. " Graefe‘s Arch Clin Exp Ophthalmol 229 : 84-87


69

37. Heldin C.H., Miyazono K. und ten Dijke P. (1997 ): "TGF-ß signalling from membrane to nucleus through SMAD proteins" . Nature 390 : 465-471

38. Hurst J.S., Balazy M., Bazan H.E.P. und Bazan N.G. (1991 ): "The epithelium, endothelium and stroma of the rabbit cornea generate 12-S-HETE as the main Lipoxygenase metabolite in response to injury." J Biol Chem 266 : 6726-6730

39. Jampel H.D., Roche N., Stark W.J. und Roberts A.B. (1990 ): "Transforming growth factor -ß in human aqueous humor" . Curr Eye Res 9 : 963-969

40. Jampel H.D . (1990 ): "Ascorbic acid is cytotoxic to dividing human Tenon‘s capsule fibroblasts." Arch Ophthalmol 108 . 1323-1325

41. Joyce N.C. und Zieske J.D. (1997 ): "Transforming growth factor-ß receptor expression in human cornea" . Inv Ophthalmol Vis Sci 38 :1922-1928

42. Kaiser C.J., Ksander B.R. und Streilein J.W. (1989 ): "Inhibition of lymphocyte proliferation by aqueous humor" . Reg Immunol 2 : 42-49

43. Kaufman H.E., Barron B.A., McDonald M.B. und Waltman S.R . : The cornea . New York 1988

44. Kay E., Lee M., Seong G. und Lee Y.G . (1998 ): "TGF-ßs stimulate cell proliferation via an autocrine production of FGF-2 in corneal stromal fibroblasts" . Curr Eye Res 17 : 286-293

45. Knisely T.L., Bleicher P.A., Vibbard C.A. und Granstein R.D. (1991 ): "Production of latent transforming growth factor-beta and other inhibitory factors by cultured iris and ciliary body cells" . Curr Eye Res 10 : 761-771

46. Knorr M., Wunderlich K., Steuhl K.P. und Thiel H.J. (1996 ): "Wirkung von Heparin und Ascorbinsäure auf das Wachstumsverhalten kultivierter Hornhautepithelzellen des Kaninchens" . Der Ophthalmologe 93 :275-278

47. Kurosaka D.und Nagamoto T . (1994 ): "Inhibitory effect of TGF-ß2 in human aqueous humor on bovine lens epithelial cell proliferation" . Invest Ophthalmol Vis Sci 35 : 3408-3412

48. Ledbetter S.R., Hatchell D.L. und O´Brien W.J . (1983 ): "Secondary aqueous humor stimulates the proliferation of cultured bovine corneal endothelial cells" . Invest Ophthalmol Vis Sci 24 : 557-562

49. Lin H.Y., Wang X.F., Ng-Eaton E., Weinberg R.A. und Lodish H.F. (1992 ): "Expression cloning of the TGF-ß type II receptor, a functional transmembrane serine/threonine kinase" . Cell (Cambridge, Mass. ) 68 :775-785

50. Lin L-R. Chakrapani B., Giblin F.J. und Reddy V.N. (1994 ): "The effect of aqueous humor ascorbate on UV-B-induced DNA damage in lens epithelium" . Invest Ophthalmol Vis Sci 35 , (Suppl.), 2134

51. Liso R., Calabrese G., Bitonti M.B. und Arrigoni O . (1984 ): "Relationship between ascorbic acid and cell division" . Exp Cell Res 150 :314-320

52. Lobb R.R. und Fett J.W. (1984 ): "Purification of two distinct growth factors from bovine neural tissue by heparin affinity chromatography" . Biochemistry 24 :6295-6299

53. Lopez-Casillas F., Cheifetz S., Doody J., Andres J.L., Lane W.S. und Massague´J . (1991 ): "Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-ß receptor system" . Cell (Cambridge, Mass .) 67 :785-795

54. Lopez-Casillas R., Wrana J.L. und Massague´ J. (1993 ):, "Betaglycan presents ligand to the TGF-ß signaling receptor" . Cell 73 :1435-1444


70

55. Lopez J.G., Hagenah M. und Insler : "Growth factors and corneal endothelial wound healing" . in Beuerman R.W., Crosson C.E. und Kaufman H. E. (Hrsg.): Healing processes in the cornea , 1989 , S. 139-150

56. Lyons R.M., Keski-Oja J. und Moses H.L. (1988 "): Proteolytic activation of latent transforming growth factor-ß from fibroblast-conditioned medium" . J Cell Biol . 106 : 1659-1665

57. Matsui J. (1929 "): Über die in-vitro Kultur des Endothels de Membrana Descemeti" . Arch f exp Zellf 8 :534-546

58. Mellors A.J., Nahrwold D.L. und Rose R.C . (1977 ): "Ascorbic acid flux across the mucosal border of guinea pig and human ileum" . Am J Physiol 233 : 347

59. Miyazono K., ten Dijke P., Ichijo H. und Heldin C.H . (1993 "): Receptors for Transforming growth factor ß. Advances in Immunology " 55 :181-220

60. Müller H.K. und Buschke W. (1934 "): Vitamin in Linse, Kammerwasser und Blut bei normalem und pathologischem Linsenstoffwechsel" . Arch Augenheilkd 108 : 368-390

61. Nakao A., Imamura T., Souchelnytskyi S., Kawabata M., Ishisaki A., Oeda E., Tamaki K., Hanai J., Heldin C.H., Miyazono K. und ten Dijke P . (1997 ): "TGF-ß receptor-mediated signalling through Smad2, Smad3 and Smad4" . EMBO J 16 : 5353-5362

62. Needleman P., Turk J., Jakschik B.A., Morrison A.R. und Lefkowith J.B. (1986 "): Arachidonic acid metabolism" . Ann Rev Biochem 55 : 69-102

63. Nobile S. und Woodhill J.M. : Vitamin C- The mysterious Redox-system-A Trigger of life? . Boston 1981

64. Pasquale L.R., Dorman-Pease M.E., Lutty G.A., Quigley H.A. und Jampel H.D . (1993 ): "Immunolocalization of TGF-ß1, TGF-ß2 and TGF-ß3 in the anterior segment of the human eye" . Invest Ophthalmol Vis Sci 34 : 23-30

65. Raymand G.M., Jumblatt M.M., Bartels S.P. und Neufeld A.H. (1986 ): "Rabbit corneal endothelial cells in vitro. Effects of EGF" . Invest Ophthalmol Vis Sci 27 :474-479

66. Reddan J.R., Weinsieder A. und Wilson D. (1979 ): "Aqueous humor from traumatized eyes triggers cell division in the epithelia of cultured lenses" . Exp Eye Res 28 : 267

67. Reddan J.R. und Wilson-Dziedzic D. (1983 "): Insulin growth factor and epidermal growth factor trigger mitosis in lenses cultured in a serum-free medium" . Invest Ophthalmol Vis Sci 24 :409-416

68. Reiss G.R., Warness P.G., Zollmann P.E. und Brubaker R.F. (1986 ): "Ascorbic acid levels in the aqueous humor of nocturnal and diurnal mammals" . Arch Ophthalmol 104 : 753-755

69. Rieck P., Hartmann C., Jacob C., Pouliquen Y. und Courtois Y. (1992 ): "Human recombinant bFGF stimulates corneal endothelial wound healing in rabbits" . Curr Eye Res 11 :1161-1172

70. Rieck P., Oliver L., Engelmann K., Fuhrmann G., Hartmann C und Courtois Y. (1995 ): "The role of exogenous/endogenous Basic Fibroblast Growth Factor (FGF2) and Transforming Growth Factor ß (TGF-ß1) on human corneal endothelial cells proliferation in vitro" . Exp Cell Res 220 : 36-46

71. Ringvold A. (1980 ): "Aqueous humor and ultraviolet radiation" . Acta Ophthalmol 58 : 69-82

72. Ringvold A. (1996 ): "The significance of ascorbate in the aqueous humor protection against UV-A and UV-B" . Exp Eye Res 62 : 261-264

73. Rocha G., Baines M.G., Deschenes J., Duclos A.J. und Antecka E. (1993 ): "Transforming growth factor-ß levels in aqueous humor during experimentally induced uveitis" . Ocular Immunol Inflamm 1 : 343-354


71

74. Rose R.C. (1988 ): "Transport of ascorbic acid and other water-soluble vitamins" . Biochem Biophys Acta 947 : 335

75. Rose R.C. (1989 ): "Renal metabolism of the oxidized form of ascorbic acid (dehydro-L-ascorbic acid)" . Am J Physiol 256 : 52

76. Rose R.C., Choi J.L. und Bode A.M. (1992 ): "Short term effects of oxidized ascorbic acid on bovine corneal endothelium and human placenta" . Life Sci 50 : 1543-1549

77. Sankar S., Mahooti-Brooks N., Centrella M., McCarthy T.L. und Madri J.A. (1995 ): "Expression of transforming growth factor type III receptor in vascular endothelial cells increases their responsiveness to transforming growth factor ß2" . J Biol Chem 270 : 13567-13572

78. Savage C., Das P., Finelli A.L., Townsend S.R., Sun C.Y., Baird S.E. und Padgett R.W. (1996 ): "Caenorhabditis elegans genes sma2, sma3 and sma 4 define a conserved family of transforming growth factor ß pathway components" . Proc Natl Acad Sci USA 93 : 790-794

79. Schimmelpfennig B.H. (1982 ): "Inhomogene Verteilung des menschlichen Korneaendothels" . Klin Mbl Augenheilk 180 : 350-351

80. Sekelsky J.J., Newfeld S.J., Raftery L.A., Chartoff E.H. und Gelbart W.M. (1995 ): "Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster" . Genetics 139 : 1347-1358

81. Shinoda I., Tokida N., Kurobe M., Furukawa S. und Hayashi K. (1988 ): "Demonstration of a considerable amount of mouse epidermal growth factor in aqueous humor" . Biochem Int 17 :243-248

82. Socci R.R. und Declamere N.A. (1988 ): "Characteristics of ascorbate transport in the rabbit iris-ciliary body" . Exp Eye Res 46 : 853

83. Souchelnytskyi S., ten Dijke P., Miyazono K. und Heldin C.H . (1996 "): Phosphorylation of Ser 165 in TGF-ß type I receptor modulates TGF-ß1 induced cellular response" . EMBO J 15 : 6231-6240

84. Sporn M.B. und Roberts A.B .: "The multifunctional nature of peptide growth factors" , in Sporn M.B. und Roberts A.B.(Hrsg.): Peptide growth factors and their receptors I. Berlin, Heidelberg, New York, London, Paris, Tokyo, Hong Kong 1990 , S.3-15

85. Taylor M.J. (1986 ): "Clinical cryobiology of tissue preservations of corneas" . Cryobiology 23 : 323

86. ten Dijke P., Hanson P., Iwata K.K., Pieler C. und Foulkes J.G . (1988 ): "Identification of a new member of the transforming growth factor ß gene family" . Proc Natl Acad Sci USA 85 :4715-4719

87. Thomas K.A., Rios-Cadelore M. und Fitzpatrick S. (1984 ): "Purification and characterization of acidic fibroblast Growth factor from bovine brain" . Proc Natl Acad Sci USA 81 :357-361

88. Treffers W.F . (1982 ): "Human corneal endothelial wound repair" . Ophthalmology 89 :605-613

89. Tripathi R.C., Li J., Chan W.F. und Tripathi B.J . (1994 ): "Aqueous humor in glaucomatous eyes contains an increased level of TGF-ß2" . Exp Eye Res 59 : 723-728

90. Usui T., Takase M., Kaji Y., Suzuki K., Ishida K., Tsuru T., Miyata K., Kawabata M. und Yamashita H. (1998 ): "Extracellular matrix production regulation by TGF-ß in corneal endothelial cells" . Invest Ophthalmol Vis Sci 39 : 1981-1989

91. Wang X.F., Lin H.Y., Ng-Eaton E., Downward J., Lodish H.F. und Weinberg R.A. (1991 ): "Expression cloning and characterization of the TGF-ß type III receptor" . Cell (Cambridge, Mass .) 67 :797-805


72

92. Waring G.O., Bourne W.M., Edelhauser H.F. und Kenyon K.R. (1982 ): "The corneal endothelium: normal and pathologic structure and function" . Ophthalmol 89 (6): 531-590

93. Waring G.O. (1992 ): Refractive keratotomy for myopia and astigmatism . St. Louis MO (USA)

94. Watanabe K., Nakagawa S.und Nishida T. (1987 ): "Stimulatory effects of fibronectin and EGF on migration of corneal epithelial cells" . Invest Ophthalmol Vis Sci 28 :205-211

95. Weinsieder A., Briggs R., Reddan J., Rothstein H., Wilson D. und Harding C.V. (1975 ): "Induction of mitosis in ocular tissue by chemotoxic agents" . Exp Eye Res 20 : 33

96. Willams R.N. und Paterson C. (1986 ): "Modulation of Corneal Lipoxygenase by Ascorbic Acid" . Exp Eye Res 43 : 7-13

97. Wilson S.E., Schultz G.S., Chegini N., Wenig J. und He Y . (1994 ): "Epidermal Growth factor, Transforming growth factor alpha, Transforming growth factor beta, Acidic fibroblast growth factor, Basic fibroblast growth factor and Interleukin-1 proteins in the cornea" . Exp Eye Res 59 :63-72

98. Wrana J.L., Attisano L., Wieser R., Ventura F. und Maasagué J. (1994 ): "Mechanism of activation of the TGF-ß receptor" . Nature 370 : 341-347

99. Wunderlich K., Knorr M., Dartsch P.C., Steuhl K.P. und Thiel H.J. (1992 ): "Die Ascorbinsäure- Zytotoxischer Effekt auf kultivierte bovine Linsenepithelzellen" . Ophthalmologe 89 : 313-318

100. Yamashita H., ten Dijke P., Franzén P., Miyazono K. und Heldin C.H. (1994 "): Formation of heterooligomeric complexes of type I and type II receptors for transforming growth factor ß" . J Biol Chem 269 : 20172-20178

101. Yue B.Y.J.T., Niedra R. und Baum J.L. (1980 ): "Effects of ascorbic acid on cultured rabbit corneal endothelial cells" . Invest Ophthalmol Vis Sci 12 : 1471-1476

102. Zadunaisky J.A. : "Transport in eye epithelia: ciliary body and retina pigment epithelium" . in Giebisch G, Tosteson D.C. und Ussing H.H. (Hrsg.): Membrane transport in biology , Berlin, Heidelberg, New York 1978 , S. 337-354

103. Zagorski Z .: "Replication capacity of the regenerating human corneal endothelium in organ culture" . in Naumann G.O.H. und Gloor B.P. (Hrsg.): Wundheilung des Auges und ihre Komplikationen , München 1980 ,


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