<?xml version="1.0" encoding="ISO-8859-1"?><cms:container xmlns:cms="http://edoc.hu-berlin.de/diml/module/cms"><cms:document><cms:meta><cms:entry id="front" part="front" ref="front" type="front"/><cms:entry type="title">Arthritisinduktion durch Immunität gegen ein systemisch exprimiertes Autoantigen &#8211; Untersuchung im Tiermodell und bei Patienten</cms:entry><cms:entry type="author">David  Schubert</cms:entry><cms:entry id="N1004F" part="N1004F" ref="N1004F" type="preface">
            Zielsetzung der Arbeit</cms:entry><cms:entry id="N10053" part="N1004F" ref="N10053" type="pagenumber">1</cms:entry><cms:entry id="chapter1" part="chapter1" ref="chapter1" type="chapter">1</cms:entry><cms:entry id="N10082" part="chapter1" ref="N10082" type="pagenumber">2</cms:entry><cms:entry id="N10086" part="chapter1" ref="N10086" type="section">1.1</cms:entry><cms:entry id="N100A3" part="chapter1" ref="N100A3" type="mm">379#261</cms:entry><cms:entry id="N100AE" part="chapter1" ref="N100AE" type="pagenumber">3</cms:entry><cms:entry id="N100B2" part="chapter1" ref="N100B2" type="subsection">1.1.1</cms:entry><cms:entry id="N100E0" part="chapter1" ref="N100E0" type="subsection">1.1.2</cms:entry><cms:entry id="N100E6" part="chapter1" ref="N100E6" type="pagenumber">4</cms:entry><cms:entry id="N10119" part="chapter1" ref="N10119" type="subsection">1.1.3</cms:entry><cms:entry id="N10132" part="chapter1" ref="N10132" type="pagenumber">5</cms:entry><cms:entry id="N10136" part="chapter1" ref="N10136" type="mm">454#321</cms:entry><cms:entry id="N10149" part="chapter1" ref="N10149" type="pagenumber">6</cms:entry><cms:entry id="N10159" part="chapter1" ref="N10159" type="subsection">1.1.4</cms:entry><cms:entry id="N1017E" part="chapter1" ref="N1017E" type="pagenumber">7</cms:entry><cms:entry id="N10182" part="chapter1" ref="N10182" type="section">1.2</cms:entry><cms:entry id="N101BF" part="chapter1" ref="N101BF" type="pagenumber">8</cms:entry><cms:entry id="N101C7" part="chapter1" ref="N101C7" type="subsection">1.2.1</cms:entry><cms:entry id="N101DD" part="chapter1" ref="N101DD" type="block">1.2.1.1</cms:entry><cms:entry id="N10202" part="chapter1" ref="N10202" type="pagenumber">9</cms:entry><cms:entry id="N10252" part="chapter1" ref="N10252" type="block">1.2.1.2</cms:entry><cms:entry id="N10260" part="chapter1" ref="N10260" type="pagenumber">10</cms:entry><cms:entry id="N10286" part="chapter1" ref="N10286" type="block">1.2.1.3</cms:entry><cms:entry id="N10298" part="chapter1" ref="N10298" type="pagenumber">11</cms:entry><cms:entry id="N102A3" part="chapter1" ref="N102A3" type="block">1.2.1.4</cms:entry><cms:entry id="N102C8" part="chapter1" ref="N102C8" type="subsection">1.2.2</cms:entry><cms:entry id="N102CE" part="chapter1" ref="N102CE" type="pagenumber">12</cms:entry><cms:entry id="N102DF" part="chapter1" ref="N102DF" type="mm">378#320</cms:entry><cms:entry id="N102F0" part="chapter1" ref="N102F0" type="block">1.2.2.1</cms:entry><cms:entry id="N1030C" part="chapter1" ref="N1030C" type="pagenumber">13</cms:entry><cms:entry id="N10324" part="chapter1" ref="N10324" type="block">1.2.2.2</cms:entry><cms:entry id="N1035B" part="chapter1" ref="N1035B" type="pagenumber">14</cms:entry><cms:entry id="N10372" part="chapter1" ref="N10372" type="block">1.2.2.3</cms:entry><cms:entry id="N103A4" part="chapter1" ref="N103A4" type="pagenumber">15</cms:entry><cms:entry id="N103C0" part="chapter1" ref="N103C0" type="block">1.2.2.4</cms:entry><cms:entry id="chapter2" part="chapter2" ref="chapter2" type="chapter">2</cms:entry><cms:entry id="N103E2" part="chapter2" ref="N103E2" type="pagenumber">16</cms:entry><cms:entry id="N103E6" part="chapter2" ref="N103E6" type="section">2.1</cms:entry><cms:entry id="N103EF" part="chapter2" ref="N103EF" type="table"/><cms:entry id="N1050A" part="chapter2" ref="N1050A" type="section">2.2</cms:entry><cms:entry id="N10510" part="chapter2" ref="N10510" type="table"/><cms:entry id="N10583" part="chapter2" ref="N10583" type="pagenumber">17</cms:entry><cms:entry id="N10848" part="chapter2" ref="N10848" type="pagenumber">18</cms:entry><cms:entry id="N10B01" part="chapter2" ref="N10B01" type="pagenumber">19</cms:entry><cms:entry id="N10BA7" part="chapter2" ref="N10BA7" type="section">2.3</cms:entry><cms:entry id="N10BAA" part="chapter2" ref="N10BAA" type="subsection">2.3.1</cms:entry><cms:entry id="N10BB0" part="chapter2" ref="N10BB0" type="table"/><cms:entry id="N10CBC" part="chapter2" ref="N10CBC" type="subsection">2.3.2</cms:entry><cms:entry id="N10CCF" part="chapter2" ref="N10CCF" type="pagenumber">20</cms:entry><cms:entry id="N10CD6" part="chapter2" ref="N10CD6" type="table"/><cms:entry id="N10EED" part="chapter2" ref="N10EED" type="pagenumber">21</cms:entry><cms:entry id="N10F6F" part="chapter2" ref="N10F6F" type="subsection">2.3.3</cms:entry><cms:entry id="N10F78" part="chapter2" ref="N10F78" type="table"/><cms:entry id="N10FD0" part="chapter2" ref="N10FD0" type="section">2.4</cms:entry><cms:entry id="N11011" part="chapter2" ref="N11011" type="pagenumber">22</cms:entry><cms:entry id="N11034" part="chapter2" ref="N11034" type="section">2.5</cms:entry><cms:entry id="N1103A" part="chapter2" ref="N1103A" type="section">2.6</cms:entry><cms:entry id="N1103D" part="chapter2" ref="N1103D" type="subsection">2.6.1</cms:entry><cms:entry id="N11043" part="chapter2" ref="N11043" type="table"/><cms:entry id="N110C8" part="chapter2" ref="N110C8" type="subsection">2.6.2</cms:entry><cms:entry id="N110CB" part="chapter2" ref="N110CB" type="pagenumber">23</cms:entry><cms:entry id="N110CF" part="chapter2" ref="N110CF" type="block">2.6.2.1</cms:entry><cms:entry id="N110D5" part="chapter2" ref="N110D5" type="table"/><cms:entry id="N11169" part="chapter2" ref="N11169" type="block">2.6.2.2</cms:entry><cms:entry id="N1116F" part="chapter2" ref="N1116F" type="table"/><cms:entry id="N111C4" part="chapter2" ref="N111C4" type="block">2.6.2.3</cms:entry><cms:entry id="N111CA" part="chapter2" ref="N111CA" type="table"/><cms:entry id="N11204" part="chapter2" ref="N11204" type="pagenumber">24</cms:entry><cms:entry id="N1124A" part="chapter2" ref="N1124A" type="block">2.6.2.4</cms:entry><cms:entry id="N11250" part="chapter2" ref="N11250" type="table"/><cms:entry id="N112D5" part="chapter2" ref="N112D5" type="block">2.6.2.5</cms:entry><cms:entry id="N112DB" part="chapter2" ref="N112DB" type="table"/><cms:entry id="N11315" part="chapter2" ref="N11315" type="block">2.6.2.6</cms:entry><cms:entry id="N1131B" part="chapter2" ref="N1131B" type="table"/><cms:entry id="N11379" part="chapter2" ref="N11379" type="pagenumber">25</cms:entry><cms:entry id="N113A3" part="chapter2" ref="N113A3" type="block">2.6.2.7</cms:entry><cms:entry id="N113A9" part="chapter2" ref="N113A9" type="table"/><cms:entry id="N11443" part="chapter2" ref="N11443" type="block">2.6.2.8</cms:entry><cms:entry id="N11449" part="chapter2" ref="N11449" type="table"/><cms:entry id="N114DA" part="chapter2" ref="N114DA" type="section">2.7</cms:entry><cms:entry id="N114E0" part="chapter2" ref="N114E0" type="table"/><cms:entry id="N1152C" part="chapter2" ref="N1152C" type="pagenumber">26</cms:entry><cms:entry id="N1168C" part="chapter2" ref="N1168C" type="section">2.8</cms:entry><cms:entry id="N11692" part="chapter2" ref="N11692" type="table"/><cms:entry id="N11759" part="chapter2" ref="N11759" type="pagenumber">27</cms:entry><cms:entry id="chapter3" part="chapter3" ref="chapter3" type="chapter">3</cms:entry><cms:entry id="N118DA" part="chapter3" ref="N118DA" type="pagenumber">28</cms:entry><cms:entry id="N118DE" part="chapter3" ref="N118DE" type="section">3.1</cms:entry><cms:entry id="N118E1" part="chapter3" ref="N118E1" type="subsection">3.1.1</cms:entry><cms:entry id="N118F7" part="chapter3" ref="N118F7" type="subsection">3.1.2</cms:entry><cms:entry id="N11914" part="chapter3" ref="N11914" type="section">3.2</cms:entry><cms:entry id="N11917" part="chapter3" ref="N11917" type="subsection">3.2.1</cms:entry><cms:entry id="N11920" part="chapter3" ref="N11920" type="table"/><cms:entry id="N11957" part="chapter3" ref="N11957" type="pagenumber">29</cms:entry><cms:entry id="N119E4" part="chapter3" ref="N119E4" type="mm">28#60</cms:entry><cms:entry id="N11B2D" part="chapter3" ref="N11B2D" type="table"/><cms:entry id="N11C5B" part="chapter3" ref="N11C5B" type="table"/><cms:entry id="N11D38" part="chapter3" ref="N11D38" type="pagenumber">30</cms:entry><cms:entry id="N11D3C" part="chapter3" ref="N11D3C" type="subsection">3.2.2</cms:entry><cms:entry id="N11D42" part="chapter3" ref="N11D42" type="section">3.3</cms:entry><cms:entry id="N11D45" part="chapter3" ref="N11D45" type="subsection">3.3.1</cms:entry><cms:entry id="N11D5D" part="chapter3" ref="N11D5D" type="subsection">3.3.2</cms:entry><cms:entry id="N11D60" part="chapter3" ref="N11D60" type="pagenumber">31</cms:entry><cms:entry id="N11D70" part="chapter3" ref="N11D70" type="subsection">3.3.3</cms:entry><cms:entry id="N11D79" part="chapter3" ref="N11D79" type="table"/><cms:entry id="N11ECD" part="chapter3" ref="N11ECD" type="pagenumber">32</cms:entry><cms:entry id="N11ED1" part="chapter3" ref="N11ED1" type="subsection">3.3.4</cms:entry><cms:entry id="N11ED7" part="chapter3" ref="N11ED7" type="subsection">3.3.5</cms:entry><cms:entry id="N11EE3" part="chapter3" ref="N11EE3" type="table"/><cms:entry id="N11F06" part="chapter3" ref="N11F06" type="pagenumber">33</cms:entry><cms:entry id="N11F13" part="chapter3" ref="N11F13" type="mm">379#45</cms:entry><cms:entry id="N11F2E" part="chapter3" ref="N11F2E" type="mm">72#41</cms:entry><cms:entry id="N11F41" part="chapter3" ref="N11F41" type="subsection">3.3.6</cms:entry><cms:entry id="N11F47" part="chapter3" ref="N11F47" type="section">3.4</cms:entry><cms:entry id="N11F4A" part="chapter3" ref="N11F4A" type="pagenumber">34</cms:entry><cms:entry id="N11F4E" part="chapter3" ref="N11F4E" type="subsection">3.4.1</cms:entry><cms:entry id="N11F57" part="chapter3" ref="N11F57" type="subsection">3.4.2</cms:entry><cms:entry id="N11F5D" part="chapter3" ref="N11F5D" type="subsection">3.4.3</cms:entry><cms:entry id="N11F66" part="chapter3" ref="N11F66" type="subsection">3.4.4</cms:entry><cms:entry id="N11F69" part="chapter3" ref="N11F69" type="pagenumber">35</cms:entry><cms:entry id="N11F79" part="chapter3" ref="N11F79" type="subsection">3.4.5</cms:entry><cms:entry id="N11F8E" part="chapter3" ref="N11F8E" type="table"/><cms:entry id="N11FB6" part="chapter3" ref="N11FB6" type="mm">359#45</cms:entry><cms:entry id="N11FC5" part="chapter3" ref="N11FC5" type="subsection">3.4.6</cms:entry><cms:entry id="N11FC8" part="chapter3" ref="N11FC8" type="pagenumber">36</cms:entry><cms:entry id="N11FD5" part="chapter3" ref="N11FD5" type="table"/><cms:entry id="N12094" part="chapter3" ref="N12094" type="pagenumber">37</cms:entry><cms:entry id="N120E0" part="chapter3" ref="N120E0" type="pagenumber">38</cms:entry><cms:entry id="N120E4" part="chapter3" ref="N120E4" type="subsection">3.4.7</cms:entry><cms:entry id="N120E7" part="chapter3" ref="N120E7" type="block">3.4.7.1</cms:entry><cms:entry id="N120ED" part="chapter3" ref="N120ED" type="block">3.4.7.2</cms:entry><cms:entry id="N120F6" part="chapter3" ref="N120F6" type="pagenumber">39</cms:entry><cms:entry id="N120FA" part="chapter3" ref="N120FA" type="block">3.4.7.3</cms:entry><cms:entry id="N12103" part="chapter3" ref="N12103" type="block">3.4.7.4</cms:entry><cms:entry id="N1210C" part="chapter3" ref="N1210C" type="pagenumber">40</cms:entry><cms:entry id="N12119" part="chapter3" ref="N12119" type="block">3.4.7.5</cms:entry><cms:entry id="N12125" part="chapter3" ref="N12125" type="section">3.5</cms:entry><cms:entry id="N12128" part="chapter3" ref="N12128" type="subsection">3.5.1</cms:entry><cms:entry id="N12134" part="chapter3" ref="N12134" type="pagenumber">41</cms:entry><cms:entry id="N1213B" part="chapter3" ref="N1213B" type="table"/><cms:entry id="N12334" part="chapter3" ref="N12334" type="table"/><cms:entry id="N123C8" part="chapter3" ref="N123C8" type="mm">41#60</cms:entry><cms:entry id="N12480" part="chapter3" ref="N12480" type="table"/><cms:entry id="N1253D" part="chapter3" ref="N1253D" type="subsection">3.5.2</cms:entry><cms:entry id="N12543" part="chapter3" ref="N12543" type="pagenumber">42</cms:entry><cms:entry id="N12547" part="chapter3" ref="N12547" type="subsection">3.5.3</cms:entry><cms:entry id="N12550" part="chapter3" ref="N12550" type="subsection">3.5.4</cms:entry><cms:entry id="N12561" part="chapter3" ref="N12561" type="pagenumber">43</cms:entry><cms:entry id="N1256E" part="chapter3" ref="N1256E" type="subsection">3.5.5</cms:entry><cms:entry id="chapter4" part="chapter4" ref="chapter4" type="chapter">4</cms:entry><cms:entry id="N12577" part="chapter4" ref="N12577" type="pagenumber">44</cms:entry><cms:entry id="N1257B" part="chapter4" ref="N1257B" type="section">4.1</cms:entry><cms:entry id="N1257E" part="chapter4" ref="N1257E" type="subsection">4.1.1</cms:entry><cms:entry id="N125C2" part="chapter4" ref="N125C2" type="pagenumber">45</cms:entry><cms:entry id="N125C6" part="chapter4" ref="N125C6" type="mm">377#563</cms:entry><cms:entry id="N125E6" part="chapter4" ref="N125E6" type="pagenumber">46</cms:entry><cms:entry id="N125F3" part="chapter4" ref="N125F3" type="mm">604#173</cms:entry><cms:entry id="N1261F" part="chapter4" ref="N1261F" type="pagenumber">47</cms:entry><cms:entry id="N12626" part="chapter4" ref="N12626" type="mm">604#173</cms:entry><cms:entry id="N12643" part="chapter4" ref="N12643" type="subsection">4.1.2</cms:entry><cms:entry id="N12650" part="chapter4" ref="N12650" type="pagenumber">48</cms:entry><cms:entry id="N1265A" part="chapter4" ref="N1265A" type="mm">604#250</cms:entry><cms:entry id="N12661" part="chapter4" ref="N12661" type="subsection">4.1.3</cms:entry><cms:entry id="N12667" part="chapter4" ref="N12667" type="pagenumber">49</cms:entry><cms:entry id="N12674" part="chapter4" ref="N12674" type="mm">303#376</cms:entry><cms:entry id="N12682" part="chapter4" ref="N12682" type="pagenumber">50</cms:entry><cms:entry id="_1161252469" part="chapter4" ref="_1161252469" type="link"/><cms:entry id="N1268F" part="chapter4" ref="N1268F" type="mm">604#378</cms:entry><cms:entry id="N1269A" part="chapter4" ref="N1269A" type="pagenumber">51</cms:entry><cms:entry id="N126A1" part="chapter4" ref="N126A1" type="table"/><cms:entry id="N12AD8" part="chapter4" ref="N12AD8" type="subsection">4.1.4</cms:entry><cms:entry id="N12ADE" part="chapter4" ref="N12ADE" type="pagenumber">52</cms:entry><cms:entry id="N12AE5" part="chapter4" ref="N12AE5" type="mm">378#284</cms:entry><cms:entry id="N12AF0" part="chapter4" ref="N12AF0" type="section">4.2</cms:entry><cms:entry id="N12AF3" part="chapter4" ref="N12AF3" type="pagenumber">53</cms:entry><cms:entry id="N12AF7" part="chapter4" ref="N12AF7" type="subsection">4.2.1</cms:entry><cms:entry id="N12B03" part="chapter4" ref="N12B03" type="table"/><cms:entry id="N12C9F" part="chapter4" ref="N12C9F" type="pagenumber">54</cms:entry><cms:entry id="N12CA6" part="chapter4" ref="N12CA6" type="mm">408#313</cms:entry><cms:entry id="N12CB1" part="chapter4" ref="N12CB1" type="subsection">4.2.2</cms:entry><cms:entry id="N12CB4" part="chapter4" ref="N12CB4" type="pagenumber">55</cms:entry><cms:entry id="N12CBE" part="chapter4" ref="N12CBE" type="mm">379#315</cms:entry><cms:entry id="N12CC9" part="chapter4" ref="N12CC9" type="pagenumber">56</cms:entry><cms:entry id="N12CCD" part="chapter4" ref="N12CCD" type="subsection">4.2.3</cms:entry><cms:entry id="N12CDC" part="chapter4" ref="N12CDC" type="pagenumber">57</cms:entry><cms:entry id="N12CE0" part="chapter4" ref="N12CE0" type="mm">583#577</cms:entry><cms:entry id="N12CEB" part="chapter4" ref="N12CEB" type="pagenumber">58</cms:entry><cms:entry id="N12CF2" part="chapter4" ref="N12CF2" type="mm">392#301</cms:entry><cms:entry id="N12D00" part="chapter4" ref="N12D00" type="mm">284#228</cms:entry><cms:entry id="N12D0B" part="chapter4" ref="N12D0B" type="pagenumber">59</cms:entry><cms:entry id="N12D0F" part="chapter4" ref="N12D0F" type="subsection">4.2.4</cms:entry><cms:entry id="N12D18" part="chapter4" ref="N12D18" type="pagenumber">60</cms:entry><cms:entry id="N12D1C" part="chapter4" ref="N12D1C" type="mm">378#774</cms:entry><cms:entry id="N12D24" part="chapter4" ref="N12D24" type="subsection">4.2.5</cms:entry><cms:entry id="N12D27" part="chapter4" ref="N12D27" type="pagenumber">61</cms:entry><cms:entry id="N12D31" part="chapter4" ref="N12D31" type="mm">379#455</cms:entry><cms:entry id="N12D3C" part="chapter4" ref="N12D3C" type="pagenumber">62</cms:entry><cms:entry id="N12D43" part="chapter4" ref="N12D43" type="subsection">4.2.6</cms:entry><cms:entry id="N12D4C" part="chapter4" ref="N12D4C" type="pagenumber">63</cms:entry><cms:entry id="N12D53" part="chapter4" ref="N12D53" type="mm">605#240</cms:entry><cms:entry id="N12D5B" part="chapter4" ref="N12D5B" type="subsection">4.2.7</cms:entry><cms:entry id="N12D64" part="chapter4" ref="N12D64" type="pagenumber">64</cms:entry><cms:entry id="N12D68" part="chapter4" ref="N12D68" type="mm">605#237</cms:entry><cms:entry id="N12D73" part="chapter4" ref="N12D73" type="subsection">4.2.8</cms:entry><cms:entry id="N12D7E" part="chapter4" ref="N12D7E" type="pagenumber">65</cms:entry><cms:entry id="N12D89" part="chapter4" ref="N12D89" type="mm">604#248</cms:entry><cms:entry id="N12D96" part="chapter4" ref="N12D96" type="subsection">4.2.9</cms:entry><cms:entry id="N12D9F" part="chapter4" ref="N12D9F" type="pagenumber">66</cms:entry><cms:entry id="N12DA3" part="chapter4" ref="N12DA3" type="mm">378#245</cms:entry><cms:entry id="N12DAE" part="chapter4" ref="N12DAE" type="section">4.3</cms:entry><cms:entry id="N12DB1" part="chapter4" ref="N12DB1" type="subsection">4.3.1</cms:entry><cms:entry id="N12DBA" part="chapter4" ref="N12DBA" type="pagenumber">67</cms:entry><cms:entry id="N12DBE" part="chapter4" ref="N12DBE" type="mm">447#337</cms:entry><cms:entry id="N12DCD" part="chapter4" ref="N12DCD" type="pagenumber">68</cms:entry><cms:entry id="N12DD4" part="chapter4" ref="N12DD4" type="mm">605#237</cms:entry><cms:entry id="N12DDF" part="chapter4" ref="N12DDF" type="subsection">4.3.2</cms:entry><cms:entry id="N12DE2" part="chapter4" ref="N12DE2" type="pagenumber">69</cms:entry><cms:entry id="N12DF2" part="chapter4" ref="N12DF2" type="mm">378#232</cms:entry><cms:entry id="N12E21" part="chapter4" ref="N12E21" type="pagenumber">70</cms:entry><cms:entry id="N12E3A" part="chapter4" ref="N12E3A" type="subsection">4.3.3</cms:entry><cms:entry id="N12E46" part="chapter4" ref="N12E46" type="pagenumber">71</cms:entry><cms:entry id="N12E4A" part="chapter4" ref="N12E4A" type="mm">604#536</cms:entry><cms:entry id="N12E57" part="chapter4" ref="N12E57" type="pagenumber">72</cms:entry><cms:entry id="N12E5B" part="chapter4" ref="N12E5B" type="subsection">4.3.4</cms:entry><cms:entry id="N12E64" part="chapter4" ref="N12E64" type="table"/><cms:entry id="N12F91" part="chapter4" ref="N12F91" type="pagenumber">73</cms:entry><cms:entry id="N12F98" part="chapter4" ref="N12F98" type="mm">575#230</cms:entry><cms:entry id="N12FA0" part="chapter4" ref="N12FA0" type="subsection">4.3.5</cms:entry><cms:entry id="N12FA9" part="chapter4" ref="N12FA9" type="pagenumber">74</cms:entry><cms:entry id="N12FAD" 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            <pagenumber id="N13D72" label="129" numbering="arabic" start="129"/>Literaturverzeichnis</head>
            
            
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