Literaturverzeichnis

Agis H, Füreder W, Bankl HC, et al. Comparative immunophenotypic analysis of human mast cells, blood basophils and monocytes. Immunology 1996;87:535-43.

Akin C & Metcalfe DD. The biology of Kit in disease and the application of pharmacogenetics. J Allergy Clin Immunol 2004;114:13-9.

Alexandrakis MG, Kyriakou DS, Seretakis D, et al. Inhibitory effect of retinoic acid on proliferation, maturation and tryptase level in human leukemic mast cells (HMC-1). Int J Immunopathol Pharmacol 2003;16:43-47.

Ashman LK. The biology of stem cell factor and its receptor C-kit. Int J Biochem Cell Biol 1999;31:1037-51.

Babina M, Guhl S, Stärke A, Kirchhof L, Zuberbier T & Henz BM. Comparative cytokine profile of human skin mast cells from two compartments - strong resemblance with monocytes at baseline, but induction of IL-5 by IL-4 priming. J Leukoc Biol 2004;75:244-52.

Babina M & Henz BM. All-trans retinoic acid down-regulates expression and function of β 2 integrins by human monocytes: opposite effects on monocytic cell lines. Eur J Immunol 2003;33:616-25.

Babina M, Mammeri K & Henz BM. Retinoic acid up-regulates myeloid ICAM-3 expression and function in a cell-specific fashion – evidence for retinoid signaling pathways in the mast cell lineage. J Leukoc Biol 2001;69:361-72.

Babina M, Schulke Y, Kirchhof L, et al. The transcription factor profile of human mast cells in comparison with monocytes and granulocytes. Cell Mol Life Sci 2005a;62:214-26.

Babina M, Thienemann F, Guhl S, et al. All-trans retinoic Acid is dedifferentiating to human maszcells. Brit J Haemtol 2005b. Zur Publikation eingereicht.

Babina M, Weber S & Henz BM. CD43 (leukosialin, sialophorin) expression is differentially regulated by retinoic acids. Eur J Immunol 1997a;27:1147-51.

Babina M, Weber S & Henz BM. Retinoic acids and dexamethasone alter cell-surface density of β 2-integrins and ICAM-1 on human leukemic (HMC-1) mast cells. Arch Dermatol Res 1997b;289:111-15.

Balmer JE & Blomhoff R. Gene expression regulation by retinoic acid. J Lipid Res 2002;43:1773-808.

Barnes JA, Singh S & Gomes AV. Protease activated receptors in cardiovascular function and disease. Mol Cell Biochem 2004;263:227-39.

Beil WJ, Schulz M & Wefelmeyer U. Mast cell granule composition and tissue location--a close correlation. Histol Histopathol 2000;15 :937-46.

Benthin M, Dallmann I & Atzpodien J. 13cis- and all-trans retinoic acid have antiproliferative effects on CML cells and render IFN alpha antiproliferative potency after combined treatment in vitro. Cancer Biother Radiopharm 2001;16:323-31.

Berg JM, Tymoczko JL, Stryer L, eds. Biochemistry. 5th ed. International Version. New York, USA : Freeman W , 2002 .

Besmer P, Murphy JE, George PC, et al. A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family. Nature 1986;320:415-21.

Bhattacharyya SN, Manna B, Ashbaugh P, Coutinho R & Kaufman B. Differentiation of respiratory epithelium: the effects of retinoic acid and carcinogens on the expression of mucociliary vs. squamous phenotype. Inflammation 1997;21:133-43.

Bischoff SC, Sellge G, Lorentz A, Sebald W, Raab R & Manns MP. IL-4 enhances proliferation and mediator release in mature human mast cells. Proc Natl Acad Sci USA 1999;96:8080-85.

Blank U, Ra C, Miller L, White K, Metzger H & Kinet JP. Complete structure and expression in transfected cells of high affinity IgE receptor. Nature 1989;337:187-9.

Breitman TR, Collins SJ & Keene BR. Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid. Blood 1981;57:1000-4.

Breitman TR, Selonick, SE & Collins SJ. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci USA 1980;77:2936-40.

Brizzi MF, Pavan M, Zini MG, Avanzi GC & Pegoraro L. Regulation of c-kit expression in human myeloid cells. Stem Cells 1993;11:42-48.

Butterfield JH, Weiler D, Dewald G & Gleich GJ. Establishment of an immature mast cell line from a patient with mast cell leukemia. Leuk Res 1988;12:345-55.

Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J 1996;10:940-54.

Chatila TA. Interleukin-4 receptor signaling pathways in asthma pathogenesis. Trends Mol Med 2004;10:493-9.

Chomienne C, Fenaux P & Degos L. Retinoid differentiation therapy in promyelocytic leukemia. FASEB J 1996;10:1025-30.

Church MK & Clough GF. Human skin mast cells: in vitro and in vivo studies. Ann Allergy Asthma Immunol 1999;83:471-5.

Coelho AM, Ossovskaya V & Bunnett NW. Proteinase-activated receptor-2: physiological and pathophysiological roles. Curr Med Chem Cardiovasc Hematol Agents 2003;1:61-72.

Collins SJ. The role of retinoids and retinoic acid receptors in normal hematopoiesis. Leukemia 2002;16:1896-905.

Costa JJ, Demetri GD, Harrist TJ, et al. Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo. J Exp Med 1996;183:2681-6.

Cruz AC, Frank BT, Edwards ST, Dazin PF, Peschon JJ & Fang KC. Tumor necrosis factor-alpha-converting enzyme controls surface expression of c-Kit and survival of embryonic stem cell-derived mast cells. J Biol Chem 2004;279:5612-20.

Czarnetzki BM, Grabbe J, Kolde G, Kruger-Krasagakes S, Welker P & Zuberbier T. Mast cells in the cytokine network: the what, where from and what for. Exp Dermatol 1995;4: 221-6.

Dawson MI. Synthetic retinoids and their nuclear receptors. Curr Med Chem Anti-Canc Agents 2004;4:199-230.

De Luca LM. Retinoids and their receptors in differentiation, embryogenesis, and neoplasia. FASEB J 1991;5:2924-33.

Dimberg A, Bahram F, Karlberg I, Larsson LG, Nilsson K & Oberg F. Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27Kip1. Blood 2002;99:2199-206.

Doggrell SA & Wanstall JC. Vascular chymase: pathophysiological role and therapeutic potential of inhibition. Cardiovasc Res 2004;61:653-62.

Dolle L, Adriaenssens E, El Yazidi-Belkoura I, Le Bourhis X, Nurcombe V & Hondermarck H. Nerve growth factor receptors and signaling in breast cancer. Curr Cancer Drug Targets 2004;4:463-70.

Dombrowicz D, Flamand V, Brigman KK, Koller BH & Kinet JP. Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor α -chain gene. Cell 1993;75:969-76.

Douer D, Ramezani L, Parker J & Levine AM. All-trans-retinoic acid effects the growth, differentiation and apoptosis of normal myeloid progenitors derived from purified CD34+ bone marrow cells. Leukemia 2000;14:874-81.

Ehrlich P. Beiträge zur Kenntnis der granulierten Bindegewebszellen und der eosinophilen Leukozyten. Arch Anat Physiol 1879;3:166-69.

Enerback L. Mucosal mast cells in the rat and in man. Int Arch Allergy Appl Immunol 1987;82:249-55.

Fenaux P, Chomienne C & Degos L. Treatment of acute promyelocytic leukaemia. Best Pract Res Clin Haematol 2001;14:153-74.

Forsythe P & Ennis M. Clinical consequences of mast cell heterogeneity. Inflamm Res 2000;49:147-54.

Fritsch P & Vanscheidt W. Flowzytometrie in der Dermatologie. Hautarzt 1996;47:561-78.

Frossard N, Freund V & Advenier C. Nerve growth factor and its receptors in asthma and inflammation. Eur J Pharmacol 2004;500:453-65.

Fung-Leung WP, Thurmond RL, Ling P & Karlsson L. Histamine H4 receptor antagonists: the new antihistamines? Curr Opin Investig Drugs. 2004;5:1174-83.

Furitsu T, Tsujimura T, Tono T, et al. Identification of mutations in the coding region of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. J Clin Invest 1993;92:1736-44.

Galli SJ, Maurer M & Lantz CS. Mast cells as sentinels of innate immunity. Curr Opin Immunol 1999;11:53-59.

Galli SJ & Wershil BK. The two faces of the mast cell. Nature 1996;381:21-2.

Geiger T, Andus T, Klapproth J, Hirano T, Kishimoto T & Heinrich PC. Induction of rat acute-phase proteins by interleukin 6 in vivo. Eur J Immunol 1988;18:717-21.

Goli M & Brown S. HPLC method for quantification of 13-cis retinoic acid (13-cis ra) subjected to light and heat treatments. Mississippi Academy of Sciences (MAS). (Accessed April 20, 2005, at http://www.msacad.org/showabstracts/?id=206)

Gollnick HP & Krautheim A. Topical treatment in acne: current status and future aspects. Dermatology 2003;206:29-36.

Grabbe J, Welker P, Dippel E & Czarnetzki BM. Stem cell factor, a novel cutaneous growth factor for mast cells and melanocytes. Arch Dermatol Res 1994;287:78-84.

Groneberg DA, Serowka F, Peckenschneider N, et al. Gene expression and regulation of nerve growth factor in atopic dermatitis mast cells and the human mast cell line-1. J Neuroimmunol 2005;161:87-92.

Grutzkau A, Kruger-Krasagakes S, Baumeister H, et al. Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206. Mol Biol Cell 1998 ;9:875-84.

Gudas LJ, Sporn MB & Roberts AB. Cellular biology and biochemistry of the retinoids. In: Sporn MB, Roberts BS, Goodman DS, eds. The retinoids: biology, chemistry, and medicine. New York, USA: Raven Press, 1994:443-520.

Guhl S, Hartmann K, Tapkenhinrichs S, et al. Ultraviolet irradiation induces apoptosis in human immature, but not in skin mast cells. J Invest Dermatol 2003;121:837-44.

Hakimi J, Seals C, Kondas J, Pettine L, Danho W & Kochan J. The α subunit of the human IgE receptor (Fc ε RI) is sufficient for high affinity IgE binding. J Biol Chem 1990;265:22079-81.

Hamann K, Grabbe J, Welker P, Haas N, Algermissen B & Czarnetzki BM. Phenotypic evaluation of cultured human mast and basophilic cells and of normal human skin mast cells. Arch Dermatol Res 1994;286:380-5.

Harris P & Ralph P. Human leukemic models of myelomonocytic development: a review of the HL-60 and U937 cell lines. J Leukoc Biol 1985;37:407-22.

Hart PH, Bonder CS, Balogh J, Dickensheets HL, Donnelly RP & Finlay-Jones JJ. Differential responses of human monocytes and macrophages to IL-4 and IL-13. J Leukoc Biol 1999;66:575-8.

Hasegawa S, Pawankar R, Suzuki K, et al. Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes. Blood 1999;93:2543-51.

Hayashi S, Kunisada T, Ogawa M & Nishikawa S. Identification of the control regions for mouse c-kit gene transcription induced by retinoic acid. DNA Res 1995;2:211-18.

Heinrich MC & Corless CL. Gastric GI stromal tumors (GISTs): the role of surgery in the era of targeted therapy. J Surg Oncol 2005;90:195-207.

Henz BM, Maurer M, Lippert U, Worm M & Babina M. Mast cells as initiators of immunity and host defense. Exp Dermatol 2001;10:1-10.

Herault O, Domenech J, Degenne M, et al. All-trans-retinoic acid up-regulates CD38 but not c-Kit antigens on human marrow CD34+ cells without recruitment into cell cycle. Br J Haematol 1998;103:343-50.

Hjertson M, Kivinen PK, Dimberg L, Nilsson K, Harvima IT & Nilsson G. Retinoic acid inhibits in vitro development of mast cells but has no marked effect on mature human skin tryptase- and chymase-positive mast cells. J Invest Dermatol 2003;120:239-45.

Holgate ST, Church MK & Kapp A. Allergologie. München: Urban & Fischer, 1996.

Humphries DE, Wong GW, Friend DS, et al. Heparin is essential for the storage of specific granule proteases in mast cells. Nature 1999;400:769-72.

Huntley JF. Mast cells and basophils: a review of their heterogeneity and function. J Comp Pathol 1992;107:349-72.

Irani AM, Nilsson G, Miettinen U, et al. Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells. Blood 1992;80:3009-21.

Irani AM & Schwartz LB. Human mast cell heterogeneity. Allergy Proc 1994;15:303-8.

Ishida S, Kinoshita T, Sugawara N, Yamashita T & Koike K. Serum inhibitors for human mast cell growth: possible role of retinol. Allergy 2003;58:1044-52.

Iwakiri R, Inokuchi K, Dan K & Nomura T. Marked basophilia in acute promyelocytic leukaemia treated with all-trans retinoic acid: molecular analysis of the cell origin of the basophils. Br J Haematol 1994;86:870-72.

Jablonowski JA, Carruthers NI & Thurmond RL. The histamine H4 receptor and potential therapeutic uses for H4 ligands. Mini Rev Med Chem 2004 ;4:993-1000.

James SY, Williams MA, Kelsey SM, Newland AC & Colston KW. The role of vitamin D derivatives and retinoids in the differentiation of human leukaemia cells. Biochem Pharmacol 1997;54:625-34.

Jensen BM, Dissing S, Skov PS & Poulsen LK. A Comparative Study of the Fc ε RI Molecule on Human Mast Cell and Basophil Cell Lines. Int Arch Allergy Immunol 2005;137:93-103.

Jutel M, Watanabe T, Akdis M, Blaser K & Akdis CA. Immune regulation by histamine. Curr Opin Immunol 2002; 14: 735-40.

Kallen KJ, Galle PR & Rose-John S. New developments in IL-6 dependent biology and therapy: where do we stand and what are the options? Expert Opin Investig Drugs 1999;8:1327-49.

Kambe M, Kambe N, Oskeritzian CA, Schechter N & Schwartz LB. IL-6 attenuates apoptosis, while neither IL-6 nor IL-10 affect the numbers or protease phenotype of fetal liver-derived human mast cells. Clin Exp Allergy 2001 ; 31 :1077-85.

Kambhampati S, Verma A, Li Y, Parmar S, Sassano A & Platanias LC. Signalling pathways activated by all-trans-retinoic acid in acute promyelocytic leukemia cells. Leuk Lymphoma 2004;45 :2175-85.

Kanbe N, Kurosawa M, Miyachi Y, Kanbe M, Saitoh H & Matsuda H. Nerve growth factor prevents apoptosis of cord blood-derived human cultured mast cells synergistically with stem cell factor. Clin Exp Allergy 2000;30:1113-20.

Kastner P, Mark M & Chambon P. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life? Cell 1995;83:859-69.

Kinet JP. The high-affinity IgE receptor (Fc ε RI): from physiology to pathology. Ann Rev Immunol 1999;17:931-72.

Kinoshita T, Koike K, Mwamtemi HH, et al. Retinoic acid is a negative regulator for the differentiation of cord blood-derived human mast cell progenitors. Blood 2000;95:2821-28.

Kinoshita T, Sawai N, Hidaka E, Yamashita T & Koike K. Interleukin-6 directly modulates stem cell factor-dependent development of human mast cells derived from CD34(+) cord blood cells. Blood 1999;94:496-508.

Kirshenbaum AS, Akin C, Wu Y, et al. Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of Fc ε RI or Fc γ RI. Leukemia Res 2003;27:677-82.

Kirshenbaum AS, Goff JP, Semere T, Foster B, Scott LM & Metcalfe DD. Demonstration that human mast cells arise from a progenitor cell population that is CD34+, c-kit+, and expresses aminopeptidase N (CD13). Blood 1999;94:2333-42.

Kitamura Y, Go S & Hatanaka S. Decrease of mast cells in W/W V mice and their increase by bone marrow transplantation. Blood 1978;52:447-52.

Kitamura Y & Hirotab S. Kit as a human oncogenic tyrosine kinase. Cell Mol Life Sci 2004;61:2924-31.

Kitamura Y, Kasugai T, Arizono N & Matsuda H. Development of mast cells and basophils: processes and regulation mechanisms. Am J Med Sci 1993;306:185-91.

Klinke R & Silbernagl S. Lehrbuch der Physiologie. Stuttgart: Thieme Verlag Stuttgart, 2003.

Kreutz M, Fritsche J, Ackermann U, Krause SW & Andreesen R. Retinoic acid inhibits monocyte to macrophage survival and differentiation. Blood 1998;91:4796-802.

Kruger-Krasagakes S, Moller A, Kolde G, Lippert U, Weber M & Henz BM. Production of interleukin-6 by human mast cells and basophilic cells. Invest Dermatol 1996;106:75-9.

Lad SP, Neet KE & Mufson EJ. Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Curr Drug Targets CNS Neurol Disord 2003;2:315-34.

Lambiase A, Micera A, Sgrulletta R, Bonini S & Bonini S. Nerve growth factor and the immune system: old and new concepts in the cross-talk between immune and resident cells during pathophysiological conditions. Curr Opin Allergy Clin Immunol 2004;4:425-30.

Lawson ND & Berliner N. Neutrophil maturation and the role of retinoic acid. Exp Hematol 1999;27:1355-67.

Lora JM, Al-Garawi A, Pickard MD, et al. Fc ε RI-dependent gene expression in human mast cells is differentially controlled by T helper type 2 cytokines. J Allergy Clin Immunol 2003;112:1119-126.

Lorentz A & Bischoff SC. Regulation of human intestinal mast cells by stem cell factor and IL-4. Immunol Rev 2001;179:57-60.

Lorentz A, Schwengberg S, Sellge G, Manns MP & Bischoff SC. Human intestinal mast cells are capable of producing different cytokine profiles: role of IgE receptor cross-linking and IL-4. J Immunol 2000;164:43-48.

Lorigados-Pedre L & Bergado-Rosado J. Nerve growth factor in neurodegeneration and neurorestorative therapy. Rev Neurol 2004;38:957-71.

Maden M & Hind M. Retinoic acid in alveolar development, maintenance and regeneration. Philos Trans R Soc Lond B Biol Sci 2004;359:799-808.

Maden M. The role of retinoic acid in embryonic and post-embryonic development. Proc Nutr Soc 2000;59:65-73.

Malaviya R & Georges A. Regulation of mast cell-mediated innate immunity during early response to bacterial infection. Clin Rev Allergy Immunol 2002;22:189-204.

Mangelsdorf DJ, Borgmeyer U, Heyman RA, et al. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 1992;6:329-44.

Mangelsdorf DJ, Ong ES, Dyck JA & Evans RM. Nuclear receptor that identifies a novel retinoic acid response pathway. Nature 1990;345:224-9.

Matikainen S & Hurme M. Comparison of retinoic acid and phorbol myristate acetate as inducers of monocytic differentiation. Int J Cancer 1994;57:98-103.

Maurer M, Theoharides T, Granstein RD, et al. What is the physiological function of mast cells? Exp Dermatol 2003;12:886-910.

Maurer M, Wedemeyer J, Metz M, et al. Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. Nature 2004;432:512-6.

Metcalfe DD, Baram D & Mekori YA. Mast cells. Physiol Rev 1997;77:1033-79.

Mitsui H, Furitsu T, Dvorak AM, et al. Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand. Proc Natl Acad Sci U S A 1993;90:735-9.

Moya-Garcia AA, Medina MA & Sanchez-Jimenez F. Mammalian histidine decarboxylase: from structure to function. Bioessays 2005;27:57-63.

Mueller TD, Zhang JL, Sebald W & Duschl A. Structure, binding, and antagonists in the IL-4/IL-13 receptor system. Biochim Biophys Acta 2002;1592:237-50.

Nagpal S & Chandraratna RA. Vitamin A and regulation of gene expression. Curr Opin Clin Nutr Metab Care 1998;1:341-6.

Nakahata T, Tsuji K, Tanaka R, et al. Synergy of stem cell factor and other cytokines in mast cell development. In: Kitamura Y, Yamamoto S, Galli SJ, eds. Biological and Molecular Aspects of Mast Cell and Basophil Differentitation and Function. New York, USA: Raven Press, 1995:13-24.

Nilsson G, Blom T, Kusche-Gullberg M, et al. Phenotypic characterization of the human mast-cell line HMC-1. Scand J Immunol 1994a;39:489-98.

Nilsson G, Miettinen U, Ishizaka T, Ashman LK, Irani AM & Schwartz LB. Interleukin-4 inhibits the expression of Kit and tryptase during stem cell factor-dependent development of human mast cells from fetal liver cells. Blood 1994b;84:1519-27.

Nilsson G & Nilsson K. Effects of interleukin (IL)-13 on immediate-early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL-4. Eur J Immunol 1995;25:870-73.

Nishimoto N & Kishimoto T. Inhibition of IL-6 for the treatment of inflammatory diseases. Curr Opin Pharmacol 2004;4:386-91.

Nwankwo JO. Anti-metastatic activities of all-trans retinoic acid, indole-3-carbinol and (+)-catechin in Dunning rat invasive prostate adenocarcinoma cells. Anticancer Res 2002;22:4129-35.

Olsson IL & Breitman TR. Induction of differentiation of the human histiocytic lymphoma cell line U-937 by retinoic acid and cyclic adenosine 3’:5’-monophosphate-inducing agents. Cancer Res 1982;42:3924-27.

Oskeritzian CA, Wang Z, Kochan JP, et al. Recombinant human (rh)IL-4-mediated apoptosis and recombinant human IL-6-mediated protection of recombinant human stem cell factor-dependent human mast cells derived from cord blood mononuclear cell progenitors. J Immunol 1999;163:5105-15.

Otsuki T, Sakaguchi H, Hatayama T, Wu P, Takata A & Hyodoh F. Effects of all-trans retinoic acid (ATRA) on human myeloma cells. Leuk Lymphoma 2003;44:1651-6.

Payne V & Kam PC. Mast cell tryptase: a review of its physiology and clinical significance. Anaesthesia 2004;59:695-703.

Petkovich M, Brand NJ, Krust A & Chambon P. A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature 1987;330:444-50.

Petkovich PM. Retinoic acid metabolism. J Am Acad Dermatol 2001;45:136-42.

Petruska JC & Mendell LM. The many functions of nerve growth factor: multiple actions on nociceptors. Neurosci Lett 2004;361:168-71.

Piao YF, Shi Y & Gao PJ. Inhibitory effect of all-trans retinoic acid on human hepatocellular carcinoma cell proliferation. World J Gastroenterol 2003;9:2117-20.

Pittenger G & Vinik A. Nerve growth factor and diabetic neuropathy. Exp Diabesity Res 2003;4:271-85.

Purton LE, Bernstein ID & Collins SJ. All-trans retinoic acid delays the differentiation of primitive hematopoietic precursors (lin-c-kit+Sca-1+) while enhancing the terminal maturation of committed granulocyte/monocyte progenitors. Blood 1999;94:483-95.

Purton LE, Bernstein ID & Collins SJ. All-trans retinoic acid enhances the long-term repopulating activity of cultured hematopoietic stem cells. Blood 2000;95:470-77.

Reed CE & Kita H. The role of protease activation of inflammation in allergic respiratory diseases. J Allergy Clin Immunol 2004;114:997-1008.

Ronnstrand L. Signal transduction via the stem cell factor receptor/c-Kit. Cell Mol Life Sci 2004;61 :2535-48.

Rook GA, Hernandez-Pando R, Dheda K & Teng Seah G. IL-4 in tuberculosis: implications for vaccine design. Trends Immunol 2004;25:483-8.

Rote Liste® Service GmbH. Roteliste 2005. Aulendorf: ECV Editio Cantor Verlag, 2005.

Ryan JJ, DeSimone S, Klisch G, et al. IL-4 inhibits mouse mast cell Fc ε RI expression through a STAT6-dependent mechanism. J Immunol 1998;161:6915-23.

Saatcioglu F, Claret FX & Karin M. Negative transcriptional regulation by nuclear receptors. Semin Cancer Biol 1994;5:347-59.

Saito H, Ebisawa M, Sakaguchi N, et al. Characterization of cord-blood-derived human mast cells cultured in the presence of Steel factor and interleukin-6. Int Arch Allergy Immunol 1995;107:63-5.

Sammons J, Ahmed NA, Khokher MA & Hassan HAT. Mechanisms mediating the inhibitory effect of all-trans retinoic acid on primitive hematopoietic stem cells in human long-term bone marrow. Stem Cells 2000;18:214-19.

Schechter NM, Brass LF, Lavker RM & Jensen PJ. Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts. J Cell Physiol 1998;176:365-73.

Scheffold A & Kern F. Recent developments in flow cytometry. J Clin Immunol 2000;20:400-7.

Schoeler D, Grützkau A, Henz BM, Küchler J & Krüger-Krasagakis S. Interleukin-6 enhances whereas tumor necrosis factor alpha and interferons inhibit integrin expression and adhesion of human mast cells to extracellular matrix proteins. J Invest Dermatol 2003;120:795-801.

Scholl PR & Geha RS. Physical association between the highaffinity IgG receptor (Fc γ RI) and the γ subunit of the high-affinity IgE receptor (Fc ε RI γ ). Proc Natl Acad Sci USA 1993;90:8847-50.

Schwartz LB. Clinical utility of tryptase levels in systemic mastocytosis and associated hematologic disorders. Leukemia Res 2001;25:553-62.

Shimamoto Y, Suga K, Yamaguchi M, Kuriyama K & Tomonaga M. Prophylaxis of symptoms of hyperhistaminemia after the treatment of acute promyelocytic leukemia with all-trans retinoic acid. Acta Haematol 1994;92:109-12.

Shimizu Y, Ashman LK, Du Z & Schwartz LB. Internalization of Kit together with stem cell factor on human fetal liver-derived mast cells: new protein and RNA synthesis are required for reappearance of Kit. J Immunol 1996;156:3443-9.

Shiohara M & Koike K. Regulation of mast cell development. Chem Immunol Allergy 2005;87:1-21.

Shore PA. The chemical determination of histamine. Methods Biochem Anal 1971;5:89-97.

Silbernagel S & Lang F. Taschenatlas der Physiologie. Stuttgart: Thieme Verlag, 1998.

Smith SJ, Ying S, Meng Q, et al. Blood eosinophils from atopic donors express messenger RNA for the alpha, beta, and gamma subunits of the high-affinity IgE receptor (Fc epsilon RI) and intracellular, but not cell surface, alpha subunit protein. J Allergy Clin Immunol 2000;105:309-17.

Smith W & Saba N. Retinoids as chemoprevention for head and neck cancer: where do we go from here? Crit Rev Oncol Hematol 2005;55:143-52.

Song L & Schindler C. IL-6 and the acute phase response in murine atherosclerosis. Atherosclerosis 2004;177:43-51.

Sonoda Y. Interleukin-4 - a dual regulatory factor in hematopoiesis. Leuk Lymphoma 1994;14:231-40.

Steinhoff M, Buddenkotte J, Shpacovitch V, et al. Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev 2005;26:1-43.

Steinke JW. Anti-interleukin-4 therapy. Immunol Allergy Clin North Am 2004;24:599-614.

Stryer L. Biochemie. 4.Auflage. Heidelberg: Spektrum Akademischer Verlag, 1996.

Thienemann F, Henz BM & Babina M. Regulation of mast cell characteristics by cytokines: divergent effects of interleukin-4 on immature mast cell lines versus mature human skin mast cells. Arch Dermatol Res 2004a;296:134-38.

Thienemann F, Guhl S, Rex C, et al. All-trans Retinoic Acid is Dedifferentiating to Human Mast Cells Independent of their Stage of Maturation. J Invest Dermatol 2004b;123:A6.

Torii I, Morikawa S, Harada T & Kitamura Y. Two distinct types of cellular mechanisms in the development of delayed hypersensitivity in mice: requirement of either mast cells or macrophages for elicitation of the response. Immunology 1993;78:482-90.

Toru H, Eguchi M, Matsumoto R, Yanagida M, Yata J & Nakahata T. Interleukin-4 promotes the development of tryptase and chymase double-positive human mast cells accompanied by cell maturation. Blood 1998;91:187-95.

Toru H, Ra C, Nonoyama S, Suzuki K, Yata J & Nakahata T. Induction of the high-affinity IgE receptor (Fc ε RI) on human mast cells by IL-4. Int Immunol 1996;8:1367-73.

Unger T & Li J. The role of the renin-angiotensin-aldosterone system in heart failure. J Renin Angiotensin Aldosterone Syst 2004;5:7-10.

Upham JW, Sehmi R, Hayes LM, Howie K, Lundahl J & Denburg JA. Retinoic acid modulates IL-5 receptor expression and selectively inhibits eosinophil-basophil differentiation of hemopoietic progenitor cells. J Allergy Clin Immunol 2002;109:307-13.

Valent P, Bevec D, Maurer D, et al. Interleukin 4 promotes expression of mast cell ICAM-1 antigen. Proc Natl Acad Sci USA 1991;88:3339-42.

Valent P, Spanblochl E, Sperr WR, et al. Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture. Blood 1992;80:2237-45.

Watanabe T & Ohtsu H. L-histidine decarboxylase as a probe in studies on histamine. Chem Rec 2002;2:369-76.

Watanabe T. Studies on histamine with L-histidine decarboxylase, a histamine-forming enzyme, as a probe: from purification to gene knockout. Nippon Yakurigaku Zasshi 2001;118:159-69.

Weber A, Knop J & Maurer M. Pattern analysis of human cutaneous mast cell populations by total body surface mapping. Br J Dermatol 2003;148:224-8.

Weber S, Babina M, Krüger-Krasagakes S, Grützkau A & Henz BM. A subclone (5C6) of the human mast cell line HMC-1 represents a more differentiated phenotype than the original cell line. Arch Dermatol Res 1996;288:778-82.

Weber S, Kruger-Krasagakes S, Grabbe J, Zuberbier T & Czarnetzki BM. Mast cells. Int J Dermatol 1995;34:1-10.

Welker P, Grabbe J, Gibbs B, Zuberbier T & Henz BM. Nerve growth factor- β induces mast-cell marker expression during in vitro culture of human umbilical cord blood cells. Immunology 2000;99:418-26.

Welker P, Grabbe J, Grutzkau A & Henz BM. Effects of nerve growth factor (NGF) and other fibroblast-derived growth factors on immature human mast cells (HMC-1). Immunology 1998;94:310-7.

Welle M. Development, significance, and heterogeneity of mast cells with particular regard to the mast cell-specific proteases chymase and tryptase. J Leukoc Biol 1997;61:233-45.

Xia HZ, Du Z, Craig S, et al. Effect of recombinant human IL-4 on tryptase, chymase, and Fc ε receptor type I expression in recombinant human stem cell factor-dependent fetal liver-derived human mast cells. J Immunol 1997;159:2911-21.

Yee NS, Langen H & Besmer P. Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells. J Biol Chem 1993;268:14189-201.

Yu VC, Delsert C, Andersen B, et al. RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements. Cell 1991;67:1251-66.

Zouboulis CC. Retinoids--which dermatological indications will benefit in the near future? Skin Pharmacol Appl Skin Physiol 2001;14:303-15.


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