Aharony, D. und Stein, R. L.; (1986): Kinetic mechanism of guinea pig neutrophil 5-lipoxygenase, J Biol Chem; 261 [25], Seite 11512-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3091590
Anderson, K. M.; Seed, T.; Meng, J.; Ou, D.; Alrefai, W. A. und Harris, J. E.; (1998): Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid, Anticancer Res; 18 [2A], Seite 791-800. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9615721
Andre, E. und Hou, K.W.; (1932): The presence of a lipid oxidase in soybean Glycine soya., Acad Sci; 194, Seite 645-647.
Anton, R. und Vila, L.; (2000): Stereoselective biosynthesis of hepoxilin B3 in human epidermis, J Invest Dermatol; 114 [3], Seite 554-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10692117
Avis, I.; Hong, S. H.; Martinez, A.; Moody, T.; Choi, Y. H.; Trepel, J.; Das, R.; Jett, M. und Mulshine, J. L.; (2001): Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions, Faseb J; 15 [11], Seite 2007-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11511519
Belkner, J.; Stender, H.; Holzhutter, H. G.; Holm, C. und Kuhn, H.; (2000): Macrophage cholesteryl ester hydrolases and hormone-sensitive lipase prefer specifically oxidized cholesteryl esters as substrates over their non-oxidized counterparts, Biochem J; 352 Pt 1, Seite 125-33. l
Belkner, J.; Stender, H. und Kuhn, H.; (1998): The rabbit 15-lipoxygenase preferentially oxygenates LDL cholesterol esters, and this reaction does not require vitamin E, J Biol Chem; 273 [36], Seite 23225-32. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9722553
Belkner, J.; Wiesner, R.; Rathman, J.; Barnett, J.; Sigal, E. und Kuhn, H.; (1993): Oxygenation of lipoproteins by mammalian lipoxygenases, Eur J Biochem; 213 [1], Seite 251-61. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8477699
Benz, D. J.; Mol, M.; Ezaki, M.; Mori-Ito, N.; Zelan, I.; Miyanohara, A.; Friedmann, T.; Parthasarathy, S.; Steinberg, D. und Witztum, J. L.; (1995): Enhanced levels of lipoperoxides in low density lipoprotein incubated with murine fibroblast expressing high levels of human 15-lipoxygenase, J Biol Chem; 270 [10], Seite 5191-7. l
Berger, M.; Schwarz, K.; Thiele, H.; Reimann, I.; Huth, A.; Borngraber, S.; Kuhn, H. und Thiele, B. J.; (1998): Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits, J Mol Biol; 278 [5], Seite 935-48. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9600854
Bisakowski, B.; Perraud, X. und Kermasha, S.; (1997): Characterization of hydroperoxides and carbonyl compounds obtained by lipoxygenase extracts of selected microorganisms, Biosci Biotechnol Biochem; 61 [8], Seite 1262-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9301105
Bligh, E.G. und Dyer, W.J.; (1959): A rapid method of total lipid extraction and purification., Canad J Biochem Physiol; 37, Seite 911-917.
Bocan, T. M.; Rosebury, W. S.; Mueller, S. B.; Kuchera, S.; Welch, K.; Daugherty, A. und Cornicelli, J. A.; (1998): A specific 15-lipoxygenase inhibitor limits the progression and monocyte-macrophage enrichment of hypercholesterolemia-induced atherosclerosis in the rabbit, Atherosclerosis; 136 [2], Seite 203-16. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9543090
Boeglin, W. E.; Kim, R. B. und Brash, A. R.; (1998): A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression, Proc Natl Acad Sci U S A; 95 [12], Seite 6744-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9618483
Borgeat, P.; Hamberg, M. und Samuelsson, B.; (1976): Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases, J Biol Chem; 251 [24], Seite 7816-20. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=826538
Borngraber, S.; (1996): Untersuchungen zur ortsgerichteten Mutagenese und zur Expression der Kaninchen 15-Lipoxygenase.;, ;Dissertation, Institut für Biologie, Mathematisch-Naturwissenschaftliche Fakultät I: Humboldt-Universität zu Berlin.
Borngraber, S.; Browner, M.; Gillmor, S.; Gerth, C.; Anton, M.; Fletterick, R. und Kuhn, H.; (1999): Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity, J Biol Chem; 274 [52], Seite 37345-50. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10601303
Borngraber, S.; Kuban, R. J.; Anton, M. und Kuhn, H.; (1996): Phenylalanine 353 is a primary determinant for the positional specificity of mammalian 15-lipoxygenases, J Mol Biol; 264 [5], Seite 1145-53. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9000636
Bortuzzo, C.; Hanif, R.; Kashfi, K.; Staiano-Coico, L.; Shiff, S. J. und Rigas, B.; (1996): The effect of leukotrienes B and selected HETEs on the proliferation of colon cancer cells, Biochim Biophys Acta; 1300 [3], Seite 240-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8679690
Boyd, D.H. und Adams, G.A.; (1955): An assay method for lipoxydase in animal tissue., Can J Physiol; 23, Seite 191-198.
Boyington, J. C.; Gaffney, B. J. und Amzel, L. M.; (1993): The three-dimensional structure of an arachidonic acid 15-lipoxygenase, Science; 260 [5113], Seite 1482-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8502991
Brash, A. R.; (1999): Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate, J Biol Chem; 274 [34], Seite 23679-82. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10446122
Brash, A. R.; Boeglin, W. E. und Chang, M. S.; (1997): Discovery of a second 15S-lipoxygenase in humans, Proc Natl Acad Sci U S A; 94 [12], Seite 6148-52. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9177185
Brash, A. R.; Boeglin, W. E.; Chang, M. S. und Shieh, B. H.; (1996): Purification and molecular cloning of an 8R-lipoxygenase from the coral Plexaura homomalla reveal the related primary structures of R- and S-lipoxygenases, J Biol Chem; 271 [34], Seite 20949-57. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8702854
Brash, A. R.; Hughes, M. A.; Hawkins, D. J.; Boeglin, W. E.; Song, W. C. und Meijer, L.; (1991): Allene oxide and aldehyde biosynthesis in starfish oocytes, J Biol Chem; 266 [34], Seite 22926-31. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1744085
Brinckmann, R.; Schnurr, K.; Heydeck, D.; Rosenbach, T.; Kolde, G. und Kuhn, H.; (1998): Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme, Blood; 91 [1], Seite 64-74. l
Brinckmann, R.; Topp, M. S.; Zalan, I.; Heydeck, D.; Ludwig, P.; Kuhn, H.; Berdel, W. E. und Habenicht, J. R.; (1996): Regulation of 15-lipoxygenase expression in lung epithelial cells by interleukin-4, Biochem J; 318 ( Pt 1), Seite 305-12. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8761486
Brock, T. G.; Paine, R., 3rd und Peters-Golden, M.; (1994): Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilic leukemia cells, J Biol Chem; 269 [35], Seite 22059-66. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8071328
Browner, M.; Gillmor, S.A. und Fletterick, R.; (1998): Burying a charge, Nat Struct Biol; 5, Seite 179.
Bryant, R. W.; Bailey, J. M.; Schewe, T. und Rapoport, S. M.; (1982): Positional specificity of a reticulocyte lipoxygenase. Conversion of arachidonic acid to 15-S-hydroperoxy-eicosatetraenoic acid, J Biol Chem; 257 [11], Seite 6050-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6804460
Bryant, R. W.; Schewe, T.; Rapoport, S. M. und Bailey, J. M.; (1985): Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4, J Biol Chem; 260 [6], Seite 3548-55. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2982864
Buchanan, M. R.; Horsewood, P. und Brister, S. J.; (1998): Regulation of endothelial cell and platelet receptor-ligand binding by the 12- and 15-lipoxygenase monohydroxides, 12-, 15-HETE and 13-HODE, Prostaglandins Leukot Essent Fatty Acids; 58 [5], Seite 339-46. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9690711
Cao, Y.; Pearman, A. T.; Zimmerman, G. A.; McIntyre, T. M. und Prescott, S. M.; (2000): Intracellular unesterified arachidonic acid signals apoptosis, Proc Natl Acad Sci U S A; 97 [21], Seite 11280-5. l
Celotti, F. und Laufer, S.; (2001): Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept, Pharmacol Res; 43 [5], Seite 429-36. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11394934
Chaitidis, P.; Schewe, T.; Sutherland, M.; Kuhn, H. und Nigam, S.; (1998): 15-Lipoxygenation of phospholipids may precede the sn-2 cleavage by phospholipases A2: reaction specificities of secretory and cytosolic phospholipases A2 towards native and 15-lipoxygenated arachidonoyl phospholipids, FEBS Lett; 434 [3], Seite 437-41. l
Chan, C. C.; Duhamel, L. und Ford-Hutchison, A.; (1985): Leukotriene B4 and 12-hydroxyeicosatetraenoic acid stimulate epidermal proliferation in vivo in the guinea pig, J Invest Dermatol; 85 [4], Seite 333-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2995499
Chen, C. R.; Voelkel, N. F. und Chang, S. W.; (1994): Platelet-activating factor potentiates protamine-induced lung edema. Role of eicosanoids, Am J Respir Crit Care Med; 149 [1], Seite 34-40. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8111595
Chen, X. S. und Funk, C. D.; (1993): Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies, Faseb J; 7 [8], Seite 694-701. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8500694
Chen, X. S.; Kurre, U.; Jenkins, N. A.; Copeland, N. G. und Funk, C. D.; (1994): cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases, J Biol Chem; 269 [19], Seite 13979-87. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8188678
Chen, X. S.; Sheller, J. R.; Johnson, E. N. und Funk, C. D.; (1994): Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene, Nature; 372 [6502], Seite 179-82. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7969451
Chen, Y. Q.; Duniec, Z. M.; Liu, B.; Hagmann, W.; Gao, X.; Shimoji, K.; Marnett, L. J.; Johnson, C. R. und Honn, K. V.; (1994): Endogenous 12(S)-HETE production by tumor cells and its role in metastasis, Cancer Res; 54 [6], Seite 1574-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7511046
Claeys, M.; Kivits, G. A.; Christ-Hazelhof, E. und Nugteren, D. H.; (1985): Metabolic profile of linoleic acid in porcine leukocytes through the lipoxygenase pathway, Biochim Biophys Acta; 837 [1], Seite 35-51. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2996610
Connolly, J. M. und Rose, D. P.; (1998): Enhanced angiogenesis and growth of 12-lipoxygenase gene-transfected MCF-7 human breast cancer cells in athymic nude mice, Cancer Lett; 132 [1-2], Seite 107-12. l
Conrad, D. J.; Kuhn, H.; Mulkins, M.; Highland, E. und Sigal, E.; (1992): Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase, Proc Natl Acad Sci U S A; 89 [1], Seite 217-21. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1729692
Conrad, D. J. und Lu, M.; (2000): Regulation of human 12/15-lipoxygenase by Stat6-dependent transcription, Am J Respir Cell Mol Biol; 22 [2], Seite 226-34. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10657944
Conradson, S. D.; Burgess, B. K.; Newton, W. E.; Di Cicco, A.; Filipponi, A.; Wu, Z. Y.; Natoli, C. R.; Hedman, B. und Hodgson, K. O.; (1994): Selenol binds to iron in nitrogenase iron-molybdenum cofactor: an extended x-ray absorption fine structure study, Proc Natl Acad Sci U S A; 91 [4], Seite 1290-3. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8108404
Cotgreave, I. A.; Duddy, S. K.; Kass, G. E.; Thompson, D. und Moldeus, P.; (1989): Studies on the anti-inflammatory activity of ebselen. Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C?, Biochem Pharmacol; 38 [4], Seite 649-56. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2537084
Cotgreave, I. A.; Johansson, U.; Westergren, G.; Moldeus, P. W. und Brattsand, R.; (1988): The anti-inflammatory activity of Ebselen but not thiols in experimental alveolitis and bronchiolitis, Agents Actions; 24 [3-4], Seite 313-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2459936
Crane, F.L.; Glenn, J.L. und Green, D.E.; (1956): Studies on the electron transfer system. The electron transfer particle., Biochim Biophys Acta; 22, Seite 475-487.
Cyrus, T.; Witztum, J. L.; Rader, D. J.; Tangirala, R.; Fazio, S.; Linton, M. F. und Funk, C. D.; (1999): Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice, J Clin Invest; 103 [11], Seite 1597-604. l
Datta, K.; Biswal, S. S. und Kehrer, J. P.; (1999): The 5-lipoxygenase-activating protein (FLAP) inhibitor, MK886, induces apoptosis independently of FLAP, Biochem J; 340 ( Pt 2), Seite 371-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10333477
de Groot, J. J.; Veldink, G. A.; Vliegenthart, J. F.; Boldingh, J.; Wever, R. und van Gelder, B. F.; (1975): Demonstration by EPR spectroscopy of the functional role of iron in soybean lipoxygenase-1, Biochim Biophys Acta; 377 [1], Seite 71-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=164225
De Marzo, N.; Sloane, D. L.; Dicharry, S.; Highland, E. und Sigal, E.; (1992): Cloning and expression of an airway epithelial 12-lipoxygenase, Am J Physiol; 263 [1 Pt 1], Seite 1 p preceding L1. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1636733
Desplat, V.; Dulery, C.; Praloran, V. und Denizot, Y.; (1999): Incorporation and effect of arachidonic acid on the growth of human myeloma cell lines, Mediators Inflamm; 8 [2], Seite 115-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10704149
Ding, X. Z.; Iversen, P.; Cluck, M. W.; Knezetic, J. A. und Adrian, T. E.; (1999): Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells, Biochem Biophys Res Commun; 261 [1], Seite 218-23. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10405349
Ding, X. Z.; Kuszynski, C. A.; El-Metwally, T. H. und Adrian, T. E.; (1999): Lipoxygenase inhibition induced apoptosis, morphological changes, and carbonic anhydrase expression in human pancreatic cancer cells, Biochem Biophys Res Commun; 266 [2], Seite 392-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10600514
Dixon, R. A.; Diehl, R. E.; Opas, E.; Rands, E.; Vickers, P. J.; Evans, J. F.; Gillard, J. W. und Miller, D. K.; (1990): Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis, Nature; 343 [6255], Seite 282-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2300173
Dubiel, W.; Muller, M.; Rathmann, J.; Hiebsch, C. und Rapoport, S. M.; (1981): Determination and characteristics of energy-dependent proteolysis in rabbit reticulocytes, Acta Biol Med Ger; 40 [4-5], Seite 625-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7315109
Dunham, W. R.; Carroll, R. T.; Thompson, J. F.; Sands, R. H. und Funk, M. O., Jr.; (1990): The initial characterization of the iron environment in lipoxygenase by Mossbauer spectroscopy, Eur J Biochem; 190 [3], Seite 611-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2164931
Edenius, C.; Kumlin, M.; Bjork, T.; Anggard, A. und Lindgren, J. A.; (1990): Lipoxin formation in human nasal polyps and bronchial tissue, FEBS Lett; 272 [1-2], Seite 25-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2172016
Edenius, C.; Stenke, L. und Lindgren, J. A.; (1991): On the mechanism of transcellular lipoxin formation in human platelets and granulocytes, Eur J Biochem; 199 [2], Seite 401-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1906402
Egmond, M. R.; Veldink, G. A.; Vliegenthart, J. F. und Boldingh, J.; (1973): C-11 H-abstraction from linoleic acid, the rate-limiting step in lipoxygenase catalysis, Biochem Biophys Res Commun; 54 [3], Seite 1178-84. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4796268
Fierro, I. M. und Serhan, C. N.; (2001): Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins, Braz J Med Biol Res; 34 [5], Seite 555-66. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11323741
Fiorucci, S.; Meli, R.; Bucci, M. und Cirino, G.; (2001): Dual inhibitors of cyclooxygenase and 5-lipoxygenase. A new avenue in anti-inflammatory therapy?, Biochem Pharmacol; 62 [11], Seite 1433-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11728379
Fischer, D. B.; Christman, J. W. und Badr, K. F.; (1992): Fifteen-S-hydroxyeicosatetraenoic acid (15-S-HETE) specifically antagonizes the chemotactic action and glomerular synthesis of leukotriene B4 in the rat, Kidney Int; 41 [5], Seite 1155-60. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1319518
Flatman, S.; Hurst, J. S.; McDonald-Gibson, R. G.; Jonas, G. E. und Slater, T. F.; (1986): Biochemical studies on a 12-lipoxygenase in human uterine cervix, Biochim Biophys Acta; 883 [1], Seite 7-14. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3089299
Fleming, J.; Thiele, B. J.; Chester, J.; O'Prey, J.; Janetzki, S.; Aitken, A.; Anton, I. A.; Rapoport, S. M. und Harrison, P. R.; (1989): The complete sequence of the rabbit erythroid cell-specific 15-lipoxygenase mRNA: comparison of the predicted amino acid sequence of the erythrocyte lipoxygenase with other lipoxygenases, Gene; 79 [1], Seite 181-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2777088
Folcik, V. A.; Nivar-Aristy, R. A.; Krajewski, L. P. und Cathcart, M. K.; (1995): Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques, J Clin Invest; 96 [1], Seite 504-10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7615823
Funk, C. D.; (1993): Molecular biology in the eicosanoid field, Prog Nucleic Acid Res Mol Biol; 45, Seite 67-98. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8341804
Funk, C. D.; Chen, X. S.; Johnson, E. N. und Zhao, L.; (2002): Lipoxygenase genes and their targeted disruption, Prostaglandins Other Lipid Mediat; 68-69, Seite 303-12. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12432925
Funk, C. D.; Furci, L. und FitzGerald, G. A.; (1990): Molecular cloning, primary structure, and expression of the human platelet/erythroleukemia cell 12-lipoxygenase, Proc Natl Acad Sci U S A; 87 [15], Seite 5638-42. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2377602
Funk, C. D. und Loll, P. J.; (1997): A molecular dipstick?, Nat Struct Biol; 4 [12], Seite 966-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9406540
Furstenberger, G.; Marks, F. und Krieg, P.; (2002): Arachidonate 8(S)-lipoxygenase, Prostaglandins Other Lipid Mediat; 68-69, Seite 235-43. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12432921
Gan, Q. F.; Browner, M. F.; Sloane, D. L. und Sigal, E.; (1996): Defining the arachidonic acid binding site of human 15-lipoxygenase. Molecular modeling and mutagenesis, J Biol Chem; 271 [41], Seite 25412-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8810309
Gan, Q. F.; Witkop, G. L.; Sloane, D. L.; Straub, K. M. und Sigal, E.; (1995): Identification of a specific methionine in mammalian 15-lipoxygenase which is oxygenated by the enzyme product 13-HPODE: dissociation of sulfoxide formation from self-inactivation, Biochemistry; 34 [21], Seite 7069-79. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7766617
Gao, J. X. und Issekutz, A. C.; (1993): The effect of ebselen on polymorphonuclear leukocyte and lymphocyte migration to inflammatory reactions in rats, Immunopharmacology; 25 [3], Seite 239-51. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8354640
Gao, X.; Grignon, D. J.; Chbihi, T.; Zacharek, A.; Chen, Y. Q.; Sakr, W.; Porter, A. T.; Crissman, J. D.; Pontes, J. E.; Powell, I. J. und et al.; (1995): Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer, Urology; 46 [2], Seite 227-37. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7624992
George, J.; Afek, A.; Shaish, A.; Levkovitz, H.; Bloom, N.; Cyrus, T.; Zhao, L.; Funk, C. D.; Sigal, E. und Harats, D.; (2001): 12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice, Circulation; 104 [14], Seite 1646-50. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11581143
Ghosh, J. und Myers, C. E.; (1998): Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells, Proc Natl Acad Sci U S A; 95 [22], Seite 13182-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9789062
Gillmor, S. A.; Villasenor, A.; Fletterick, R.; Sigal, E. und Browner, M. F.; (1997): The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity, Nat Struct Biol; 4 [12], Seite 1003-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9406550
Goldyne, M. E.; Burrish, G. F.; Poubelle, P. und Borgeat, P.; (1984): Arachidonic acid metabolism among human mononuclear leukocytes. Lipoxygenase-related pathways, J Biol Chem; 259 [14], Seite 8815-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6430891
Grechkin, A.; (1998): Recent developments in biochemistry of the plant lipoxygenase pathway, Prog Lipid Res; 37 [5], Seite 317-52. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10209652
Grullich, C.; Duvoisin, R. M.; Wiedmann, M. und van Leyen, K.; (2001): Inhibition of 15-lipoxygenase leads to delayed organelle degradation in the reticulocyte, FEBS Lett; 489 [1], Seite 51-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11231012
Gu, J.; Liu, Y.; Wen, Y.; Natarajan, R.; Lanting, L. und Nadler, J. L.; (2001): Evidence that increased 12-lipoxygenase activity induces apoptosis in fibroblasts, J Cell Physiol; 186 [3], Seite 357-65. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11169974
Guex, N. und Peitsch, M.C.; (1997): SWISS-MODEL and the Swiss-Pdb-Viewer: An environment for comparative protein modeling., Electrophoresis; 18, Seite 2714-2723.
Gupta, S.; Srivastava, M.; Ahmad, N.; Sakamoto, K.; Bostwick, D. G. und Mukhtar, H.; (2001): Lipoxygenase-5 is overexpressed in prostate adenocarcinoma, Cancer; 91 [4], Seite 737-43. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11241241
Hada, T.; Hagiya, H.; Suzuki, H.; Arakawa, T.; Nakamura, M.; Matsuda, S.; Yoshimoto, T.; Yamamoto, S.; Azekawa, T.; Morita, Y. und et al.; (1994): Arachidonate 12-lipoxygenase of rat pineal glands: catalytic properties and primary structure deduced from its cDNA, Biochim Biophys Acta; 1211 [2], Seite 221-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8117750
Hada, T.; Swift, L. L. und Brash, A. R.; (1997): Discovery of 5R-lipoxygenase activity in oocytes of the surf clam, Spisula solidissima, Biochim Biophys Acta; 1346 [2], Seite 109-19. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9219894
Hada, T.; Ueda, N.; Takahashi, Y. und Yamamoto, S.; (1991): Catalytic properties of human platelet 12-lipoxygenase as compared with the enzymes of other origins, Biochim Biophys Acta; 1083 [1], Seite 89-93. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1851637
Hamberg, M. und Samuelsson, B.; (1967): On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxydase., J Biol Chem; 242, Seite 5329-5335.
Hamberg, M. und Samuelsson, B.; (1974): Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets, Proc Natl Acad Sci U S A; 71 [9], Seite 3400-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4215079
Harats, D.; Shaish, A.; George, J.; Mulkins, M.; Kurihara, H.; Levkovitz, H. und Sigal, E.; (2000): Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice, Arterioscler Thromb Vasc Biol; 20 [9], Seite 2100-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10978255
Hartel, B.; Ludwig, P.; Schewe, T. und Rapoport, S. M.; (1982): Self-inactivation by 13-hydroperoxylinoleic acid and lipohydroperoxidase activity of the reticulocyte lipoxygenase, Eur J Biochem; 126 [2], Seite 353-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6813118
Hattori, R.; Inoue, R.; Sase, K.; Eizawa, H.; Kosuga, K.; Aoyama, T.; Masayasu, H.; Kawai, C.; Sasayama, S. und Yui, Y.; (1994): Preferential inhibition of inducible nitric oxide synthase by ebselen, Eur J Pharmacol; 267 [2], Seite R1-2. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7519560
Hawkins, D. J. und Brash, A. R.; (1987): Eggs of the sea urchin, Strongylocentrotus purpuratus, contain a prominent (11R) and (12R) lipoxygenase activity, J Biol Chem; 262 [16], Seite 7629-34. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3108255
Henricks, P. A.; Engels, F.; van der Vliet, H. und Nijkamp, F. P.; (1991): 9- and 13-hydroxy-linoleic acid possess chemotactic activity for bovine and human polymorphonuclear leukocytes, Prostaglandins; 41 [1], Seite 21-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2020743
Henriksen, T.; Mahoney, E. M. und Steinberg, D.; (1981): Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins, Proc Natl Acad Sci U S A; 78 [10], Seite 6499-503. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6273873
Henriksson, P.; Hamberg, M. und Diczfalusy, U.; (1985): Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall, Biochim Biophys Acta; 834 [2], Seite 272-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3995065
Herlin, T.; Fogh, K.; Hansen, E. S.; Andreasen, A.; Knudsen, V.; Henriksen, T. B.; Bunger, C. und Kragballe, K.; (1990): 15-HETE inhibits leukotriene B4 formation and synovial cell proliferation in experimental arthritis, Agents Actions; 29 [1-2], Seite 52-3. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2158220
Herrmann, J. L.; Menter, D. G.; Beham, A.; von Eschenbach, A. und McDonnell, T. J.; (1997): Regulation of lipid signaling pathways for cell survival and apoptosis by bcl-2 in prostate carcinoma cells, Exp Cell Res; 234 [2], Seite 442-51. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9260915
Heydeck, D.; Thomas, L.; Schnurr, K.; Trebus, F.; Thierfelder, W. E.; Ihle, J. N. und Kuhn, H.; (1998): Interleukin-4 and -13 induce upregulation of the murine macrophage 12/15-lipoxygenase activity: evidence for the involvement of transcription factor STAT6, Blood; 92 [7], Seite 2503-10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9746791
Higgs, G. A.; Salmon, J. A. und Spayne, J. A.; (1981): The inflammatory effects of hydroperoxy and hydroxy acid products of arachidonate lipoxygenase in rabbit skin, Br J Pharmacol; 74 [2], Seite 429-33. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6274465
Honn, K. V.; Grossi, I. M.; Diglio, C. A.; Wojtukiewicz, M. und Taylor, J. D.; (1989): Enhanced tumor cell adhesion to the subendothelial matrix resulting from 12(S)-HETE-induced endothelial cell retraction, Faseb J; 3 [11], Seite 2285-93. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2673900
Honn, K. V.; Tang, D. G.; Gao, X.; Butovich, I. A.; Liu, B.; Timar, J. und Hagmann, W.; (1994): 12-lipoxygenases and 12(S)-HETE: role in cancer metastasis, Cancer Metastasis Rev; 13 [3-4], Seite 365-96. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7712597
Hornung, E.; Walther, M.; Kuhn, H. und Feussner, I.; (1999): Conversion of cucumber linoleate 13-lipoxygenase to a 9-lipoxygenating species by site-directed mutagenesis, Proc Natl Acad Sci U S A; 96 [7], Seite 4192-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10097186
Humphrey, W.; Dalke, A. und Schulten, K.; (1996): VMD - Visual Molecular Dynamics, J Molec Graphics; 14, Seite 33-38.
Hunter, J. A.; Finkbeiner, W. E.; Nadel, J. A.; Goetzl, E. J. und Holtzman, M. J.; (1985): Predominant generation of 15-lipoxygenase metabolites of arachidonic acid by epithelial cells from human trachea, Proc Natl Acad Sci U S A; 82 [14], Seite 4633-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3927287
Hussain, H.; Shornick, L. P.; Shannon, V. R.; Wilson, J. D.; Funk, C. D.; Pentland, A. P. und Holtzman, M. J.; (1994): Epidermis contains platelet-type 12-lipoxygenase that is overexpressed in germinal layer keratinocytes in psoriasis, Am J Physiol; 266 [1 Pt 1], Seite C243-53. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8304420
Ikawa, H.; Kamitani, H.; Calvo, B. F.; Foley, J. F. und Eling, T. E.; (1999): Expression of 15-lipoxygenase-1 in human colorectal cancer, Cancer Res; 59 [2], Seite 360-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9927047
International Human Genome Sequencing Consortium; (2001): Initial sequencing and analysis of the human genome., Nature; 409, Seite 860-921.
Ishii, S.; Noguchi, M.; Miyano, M.; Matsumoto, T. und Noma, M.; (1992): Mutagenesis studies on the amino acid residues involved in the iron-binding and the activity of human 5-lipoxygenase, Biochem Biophys Res Commun; 184 [2], Seite 1133-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1575732
Ivanov, I.; Groza, N.; Romanov, S.; Kuhn, H. und Myagkova, G.; (2000): Total synthesis of the lipoxygenase substrates (5Z,8Z,11Z,14Z)-Nonadeca-5,8,11,14-tetraene-1,19-dioic acid and (5Z,8Z,11Z,14Z)-20,20-Dimethylheneicosa-5,8,11,14-tetraenoic acid., Synthesis; 5, Seite 691-694.
Janssen-Timmen, U.; Vickers, P. J.; Wittig, U.; Lehmann, W. D.; Stark, H. J.; Fusenig, N. E.; Rosenbach, T.; Radmark, O.; Samuelsson, B. und Habenicht, A. J.; (1995): Expression of 5-lipoxygenase in differentiating human skin keratinocytes, Proc Natl Acad Sci U S A; 92 [15], Seite 6966-70. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7624354
Jisaka, M.; Kim, R. B.; Boeglin, W. E. und Brash, A. R.; (2000): Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2, J Biol Chem; 275 [2], Seite 1287-93. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10625675
Johnson, E. N.; Brass, L. F. und Funk, C. D.; (1998): Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase, Proc Natl Acad Sci U S A; 95 [6], Seite 3100-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9501222
Kamitani, H.; Kameda, H.; Kelavkar, U. P. und Eling, T. E.; (2000): A GATA binding site is involved in the regulation of 15-lipoxygenase-1 expression in human colorectal carcinoma cell line, caco-2, FEBS Lett; 467 [2-3], Seite 341-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10675566
Kamitani, H.; Taniura, S.; Ikawa, H.; Watanabe, T.; Kelavkar, U. P. und Eling, T. E.; (2001): Expression of 15-lipoxygenase-1 is regulated by histone acetylation in human colorectal carcinoma, Carcinogenesis; 22 [1], Seite 187-91. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11159758
Kelavkar, U. P. und Badr, K. F.; (1999): Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator gene, Proc Natl Acad Sci U S A; 96 [8], Seite 4378-83. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10200270
Kelavkar, U. P.; Cohen, C.; Kamitani, H.; Eling, T. E. und Badr, K. F.; (2000): Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging, Carcinogenesis; 21 [10], Seite 1777-87. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11023533
Kelavkar, U. P.; Nixon, J. B.; Cohen, C.; Dillehay, D.; Eling, T. E. und Badr, K. F.; (2001): Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis, Carcinogenesis; 22 [11], Seite 1765-73. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11698337
Kishimoto, K.; Nakamura, M.; Suzuki, H.; Yoshimoto, T.; Yamamoto, S.; Takao, T.; Shimonishi, Y. und Tanabe, T.; (1996): Suicide inactivation of porcine leukocyte 12-lipoxygenase associated with its incorporation of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid derivative, Biochim Biophys Acta; 1300 [1], Seite 56-62. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8608163
Knapp, M. J. und Klinman, J. P.; (2002): Environmentally coupled hydrogen tunneling, Eur J Biochem; 269 [13], Seite 3113-21. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12084051
; ;Knapp, M. J.; Seebeck, F. P. und Klinman, J. P. ; (2001): Steric control of oxygenation regiochemistry in soybean lipoxygenase-1, J Am Chem Soc; 123 [12], Seite 2931-2. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uid
Kozak, K. R.; Gupta, R. A.; Moody, J. S.; Ji, C.; Boeglin, W. E.; DuBois, R. N.; Brash, A. R. und Marnett, L. J.; (2002): 15-Lipoxygenase Metabolism of 2-Arachidonylglycerol. GENERATION OF A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR alpha AGONIST, J Biol Chem; 277 [26], Seite 23278-86. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11956198
Krieg, P.; Marks, F. und Furstenberger, G.; (2001): A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression, Genomics; 73 [3], Seite 323-30. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11350124
Kroschwald, P.; Kroschwald, A.; Kuhn, H.; Ludwig, P.; Thiele, B. J.; Hohne, M.; Schewe, T. und Rapoport, S. M.; (1989): Occurrence of the erythroid cell specific arachidonate 15-lipoxygenase in human reticulocytes, Biochem Biophys Res Commun; 160 [2], Seite 954-60. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2719708
Kroschwald, P.; Kroschwald, A.; Wiesner, R.; Schewe, T. und Kuhn, H.; (1986): The occurrence of a lipoxygenase pathway in reticulocytes of various species, Biomed Biochim Acta; 45 [10], Seite 1237-47. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3105527
Kuban, R. J.; Wiesner, R.; Rathman, J.; Veldink, G.; Nolting, H.; Sole, V. A. und Kuhn, H.; (1998): The iron ligand sphere geometry of mammalian 15-lipoxygenases, Biochem J; 332 ( Pt 1), Seite 237-42. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9576873
Kuhn, H.; Belkner, J. und Wiesner, R.; (1990): Subcellular distribution of lipoxygenase products in rabbit reticulocyte membranes, Eur J Biochem; 191 [1], Seite 221-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2116308
Kuhn, H.; Belkner, J.; Zaiss, S.; Fahrenklemper, T. und Wohlfeil, S.; (1994): Involvement of 15-lipoxygenase in early stages of atherogenesis, J Exp Med; 179 [6], Seite 1903-11. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8195716
Kuhn, H. und Chan, L.; (1997): The role of 15-lipoxygenase in atherogenesis: pro- and antiatherogenic actions, Curr Opin Lipidol; 8 [2], Seite 111-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9183549
Kuhn, H.; Heydeck, D.; Hugou, I. und Gniwotta, C.; (1997): In vivo action of 15-lipoxygenase in early stages of human atherogenesis, J Clin Invest; 99 [5], Seite 888-93. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9062346
Kuhn, H.; Salzmann-Reinhardt, U.; Ludwig, P.; Ponicke, K.; Schewe, T. und Rapoport, S.; (1986): The stoichiometry of oxygen uptake and conjugated diene formation during the dioxygenation of linoleic acid by the pure reticulocyte lipoxygenase. Evidence for aerobic hydroperoxidase activity, Biochim Biophys Acta; 876 [2], Seite 187-93. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3006782
Kuhn, H.; Schewe, T. und Rapoport, S. M.; (1986): The stereochemistry of the reactions of lipoxygenases and their metabolites. Proposed nomenclature of lipoxygenases and related enzymes, Adv Enzymol Relat Areas Mol Biol; 58, Seite 273-311. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3087142
Kuhn, H.; Sprecher, H. und Brash, A. R.; (1990): On singular or dual positional specificity of lipoxygenases. The number of chiral products varies with alignment of methylene groups at the active site of the enzyme, J Biol Chem; 265 [27], Seite 16300-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2118902
Kuhn, H. und Thiele, B. J.; (1999): The diversity of the lipoxygenase family. Many sequence data but little information on biological significance, FEBS Lett; 449 [1], Seite 7-11. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10225417
Kuhn, H.; Thiele, B. J.; Ostareck-Lederer, A.; Stender, H.; Suzuki, H.; Yoshimoto, T. und Yamamoto, S.; (1993): Bacterial expression, purification and partial characterization of recombinant rabbit reticulocyte 15-lipoxygenase, Biochim Biophys Acta; 1168 [1], Seite 73-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8504145
Kuhn, H.; Wiesner, R.; Alder, L.; Fitzsimmons, B. J.; Rokach, J. und Brash, A. R.; (1987): Formation of lipoxin B by the pure reticulocyte lipoxygenase via sequential oxygenation of the substrate, Eur J Biochem; 169 [3], Seite 593-601. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3121318
Kulkarni, S.; Das, S.; Funk, C. D.; Murray, D. und Cho, W.; (2002): Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase, J Biol Chem; 277 [15], Seite 13167-74. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11796736
Laemmli, U.K.; (1970): Cleavage of structural proteins during the assembly of the head of bacteriophage T4., Nature; 227, Seite 680-685.
Lee, T. H.; Horton, C. E.; Kyan-Aung, U.; Haskard, D.; Crea, A. E. und Spur, B. W.; (1989): Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine, Clin Sci (Lond); 77 [2], Seite 195-203. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2548801
Lehmann, W. D.; (1994): Regio- and stereochemistry of the dioxygenation reaction catalyzed by (S)-type lipoxygenases or by the cyclooxygenase activity of prostaglandin H synthases, Free Radic Biol Med; 16 [2], Seite 241-53. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8005520
Lewis, R. A.; Austen, K. F. und Soberman, R. J.; (1990): Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases, N Engl J Med; 323 [10], Seite 645-55. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2166915
Li, Q. J.; Bessems, J. G.; Commandeur, J. N.; Adams, B. und Vermeulen, N. P.; (1994): Mechanism of protection of ebselen against paracetamol-induced toxicity in rat hepatocytes, Biochem Pharmacol; 48 [8], Seite 1631-40. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7980628
Lin, F. und Girotti, A. W.; (1994): Cytoprotection against merocyanine 540-sensitized photoinactivation of the Na+,K(+)-adenosine triphosphatase in leukemia cells: glutathione and selenoperoxidase involvement, Photochem Photobiol; 59 [3], Seite 320-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8016211
Liu, B.; Maher, R. J.; Hannun, Y. A.; Porter, A. T. und Honn, K. V.; (1994): 12(S)-HETE enhancement of prostate tumor cell invasion: selective role of PKC alpha, J Natl Cancer Inst; 86 [15], Seite 1145-51. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7518003
Liu, B.; Marnett, L. J.; Chaudhary, A.; Ji, C.; Blair, I. A.; Johnson, C. R.; Diglio, C. A. und Honn, K. V.; (1994): Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by B16 amelanotic melanoma cells is a determinant of their metastatic potential, Lab Invest; 70 [3], Seite 314-23. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8145526
Maas, R. L.; Brash, A. R. und Oates, J. A.; (1982): Novel leukotrienes and lipoxygenase products from arachidonic acid, Adv Prostaglandin Thromboxane Leukot Res; 9, Seite 29-44. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6283848
Maas, R. L.; Turk, J.; Oates, J. A. und Brash, A. R.; (1982): Formation of a novel dihydroxy acid from arachidonic acid by lipoxygenase-catalyzed double oxygenation in rat mononuclear cells and human leukocytes, J Biol Chem; 257 [12], Seite 7056-67. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6806263
Maccarrone, M.; Ranalli, M.; Bellincampi, L.; Salucci, M. L.; Sabatini, S.; Melino, G. und Finazzi-Agro, A.; (2000): Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells, Biochem Biophys Res Commun; 272 [2], Seite 345-50. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10833416
Maccarrone, M.; Salucci, M. L.; van Zadelhoff, G.; Malatesta, F.; Veldink, G.; Vliegenthart, J. F. und Finazzi-Agro, A.; (2001): Tryptic digestion of soybean lipoxygenase-1 generates a 60 kDa fragment with improved activity and membrane binding ability, Biochemistry; 40 [23], Seite 6819-27. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11389595
Mack, A. J.; Peterman, T. K. und Siedow, J. N.; (1987): Lipoxygenase isozymes in higher plants: biochemical properties and physiological role, Isozymes Curr Top Biol Med Res; 13, Seite 127-54. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3108192
Maddox, J. F.; Hachicha, M.; Takano, T.; Petasis, N. A.; Fokin, V. V. und Serhan, C. N.; (1997): Lipoxin A4 stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein-linked lipoxin A4 receptor, J Biol Chem; 272 [11], Seite 6972-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9054386
Matsumoto, T.; Funk, C. D.; Radmark, O.; Hoog, J. O.; Jornvall, H. und Samuelsson, B.; (1988): Molecular cloning and amino acid sequence of human 5-lipoxygenase, Proc Natl Acad Sci U S A; 85 [1], Seite 26-30. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2829172
May, C.; Hohne, M.; Gnau, P.; Schwennesen, K. und Kindl, H.; (2000): The N-terminal beta-barrel structure of lipid body lipoxygenase mediates its binding to liposomes and lipid bodies, Eur J Biochem; 267 [4], Seite 1100-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10672019
McNally, A. K.; Chisolm, G. M., 3rd; Morel, D. W. und Cathcart, M. K.; (1990): Activated human monocytes oxidize low-density lipoprotein by a lipoxygenase-dependent pathway, J Immunol; 145 [1], Seite 254-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2162888
Mehrabian, M.; Allayee, H.; Wong, J.; Shi, W.; Wang, X. P.; Shaposhnik, Z.; Funk, C. D.; Lusis, A. J. und Shih, W.; (2002): Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice, Circ Res; 91 [2], Seite 120-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12142344
Miller, Y. I.; Chang, M. K.; Funk, C. D.; Feramisco, J. R. und Witztum, J. L.; (2001): 12/15-lipoxygenase translocation enhances site-specific actin polymerization in macrophages phagocytosing apoptotic cells, J Biol Chem; 276 [22], Seite 19431-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11278875
Minor, W.; Steczko, J.; Stec, B.; Otwinowski, Z.; Bolin, J. T.; Walter, R. und Axelrod, B.; (1996): Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution, Biochemistry; 35 [33], Seite 10687-701. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8718858
Munger, K. A.; Montero, A.; Fukunaga, M.; Uda, S.; Yura, T.; Imai, E.; Kaneda, Y.; Valdivielso, J. M. und Badr, K. F.; (1999): Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis, Proc Natl Acad Sci U S A; 96 [23], Seite 13375-80. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10557328
Murakami, M.; Austen, K. F. und Arm, J. P.; (1995): The immediate phase of c-kit ligand stimulation of mouse bone marrow-derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5-lipoxygenase, J Exp Med; 182 [1], Seite 197-206. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7540649
Murray, J. J. und Brash, A. R.; (1988): Rabbit reticulocyte lipoxygenase catalyzes specific 12(S) and 15(S) oxygenation of arachidonoyl-phosphatidylcholine, Arch Biochem Biophys; 265 [2], Seite 514-23. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3138949
Nadel, J. A.; Conrad, D. J.; Ueki, I. F.; Schuster, A. und Sigal, E.; (1991): Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocytes, leukocytes, and airway cells, J Clin Invest; 87 [4], Seite 1139-45. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2010530
Nassar, G. M.; Morrow, J. D.; Roberts, L. J., 2nd; Lakkis, F. G. und Badr, K. F.; (1994): Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes, J Biol Chem; 269 [44], Seite 27631-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7961680
Natarajan, R.; Esworthy, R.; Bai, W.; Gu, J. L.; Wilczynski, S. und Nadler, J.; (1997): Increased 12-lipoxygenase expression in breast cancer tissues and cells. Regulation by epidermal growth factor, J Clin Endocrinol Metab; 82 [6], Seite 1790-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9177384
Natarajan, R. und Nadler, J.; (1998): Role of lipoxygenases in breast cancer, Front Biosci; 3, Seite E81-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9616130
Nelson, M. J.; Cowling, R. A. und Seitz, S. P.; (1994): Structural characterization of alkyl and peroxyl radicals in solutions of purple lipoxygenase, Biochemistry; 33 [16], Seite 4966-73. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8161558
Neuzil, J.; Upston, J. M.; Witting, P. K.; Scott, K. F. und Stocker, R.; (1998): Secretory phospholipase A2 and lipoprotein lipase enhance 15-lipoxygenase-induced enzymic and nonenzymic lipid peroxidation in low-density lipoproteins, Biochemistry; 37 [25], Seite 9203-10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9636068
Nguyen, T.; Falgueyret, J. P.; Abramovitz, M. und Riendeau, D.; (1991): Evaluation of the role of conserved His and Met residues among lipoxygenases by site-directed mutagenesis of recombinant human 5-lipoxygenase, J Biol Chem; 266 [32], Seite 22057-62. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1939225
Nickerson-Nutter, C. L. und Medvedeff, E. D.; (1996): The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation, Arthritis Rheum; 39 [3], Seite 515-21. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8607901
Nie, D.; Hillman, G. G.; Geddes, T.; Tang, K.; Pierson, C.; Grignon, D. J. und Honn, K. V.; (1998): Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth, Cancer Res; 58 [18], Seite 4047-51. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9751607
Nugteren, D. H.; (1975): Arachidonate lipoxygenase in blood platelets, Biochim Biophys Acta; 380 [2], Seite 299-307. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=804329
O'Donnell, V. B.; Spycher, S. und Azzi, A.; (1995): Involvement of oxidants and oxidant-generating enzyme(s) in tumour-necrosis-factor-alpha-mediated apoptosis: role for lipoxygenase pathway but not mitochondrial respiratory chain, Biochem J; 310 ( Pt 1), Seite 133-41. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7646435
Ochi, K.; Yoshimoto, T.; Yamamoto, S.; Taniguchi, K. und Miyamoto, T.; (1983): Arachidonate 5-lipoxygenase of guinea pig peritoneal polymorphonuclear leukocytes. Activation by adenosine 5'-triphosphate, J Biol Chem; 258 [9], Seite 5754-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6406506
Oliw, E. H.; (2002): Plant and fungal lipoxygenases, Prostaglandins Other Lipid Mediat; 68-69, Seite 313-23. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12432926
Ostareck-Lederer, A.; Ostareck, D. H.; Standart, N. und Thiele, B. J.; (1994): Translation of 15-lipoxygenase mRNA is inhibited by a protein that binds to a repeated sequence in the 3' untranslated region, Embo J; 13 [6], Seite 1476-81. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8137829
Ostareck, D. H.; Ostareck-Lederer, A.; Shatsky, I. N. und Hentze, M. W.; (2001): Lipoxygenase mRNA silencing in erythroid differentiation: The 3'UTR regulatory complex controls 60S ribosomal subunit joining, Cell; 104 [2], Seite 281-90. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11207368
Ostareck, D. H.; Ostareck-Lederer, A.; Wilm, M.; Thiele, B. J.; Mann, M. und Hentze, M. W.; (1997): mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end, Cell; 89 [4], Seite 597-606. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9160751
Papayianni, A.; Serhan, C. N. und Brady, H. R.; (1996): Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells, J Immunol; 156 [6], Seite 2264-72. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8690917
Parthasarathy, S.; Wieland, E. und Steinberg, D.; (1989): A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein, Proc Natl Acad Sci U S A; 86 [3], Seite 1046-50. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2536929
Paul, A.; Calleja, L.; Vilella, E.; Martinez, R.; Osada, J. und Joven, J.; (1999): Reduced progression of atherosclerosis in apolipoprotein E-deficient mice with phenylhydrazine-induced anemia, Atherosclerosis; 147 [1], Seite 61-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10525126
Pavlosky, M.A.; Zhang, Y.; Westre, T.E.; Gan, Q. F.; Pavel, E.; Campochiaro, C.; Hedman, B.; Hodgson, K. O. und Solomon, E. I.; (1995): Near Infrared Circular Dichroism, Magnetic Circular Dichroism and X-ray Absorption Spectral Comparison of the Non-Heme Ferrous Active Sites of Plant and Mammalian 15-Lipoxygenases., J Am Chem Soc; 117, Seite 4316-4327.
Pettifer, R.F. und Hermes, C.; (1985): Absolute energy calibration of X-ray radiation from synchrotron sources., J Appl Crystall; 18, Seite 404-412.
Pham, C.; Jankun, J.; Skrzypczak-Jankun, E.; Flowers, R. A., 2nd und Funk, M. O., Jr.; (1998): Structural and thermochemical characterization of lipoxygenase-catechol complexes, Biochemistry; 37 [51], Seite 17952-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9922163
Porta, H. und Rocha-Sosa, M.; (2001): Lipoxygenase in bacteria: a horizontal transfer event?, Microbiology; 147 [Pt 12], Seite 3199-200. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11739752
Prigge, S. T.; Boyington, J. C.; Gaffney, B. J. und Amzel, L. M.; (1996): Structure conservation in lipoxygenases: structural analysis of soybean lipoxygenase-1 and modeling of human lipoxygenases, Proteins; 24 [3], Seite 275-91. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8778775
Prigge, S. T.; Gaffney, B. J. und Amzel, L. M.; (1998): Relation between positional specificity and chirality in mammalian lipoxygenases, Nat Struct Biol; 5 [3], Seite 178-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9501907
Profita, M.; Sala, A.; Riccobono, L.; Paterno, A.; Mirabella, A.; Bonanno, A.; Guerrera, D.; Pace, E.; Bonsignore, G.; Bousquet, J. und Vignola, A. M.; (2000): 15-Lipoxygenase expression and 15(S)-hydroxyeicoisatetraenoic acid release and reincorporation in induced sputum of asthmatic subjects, J Allergy Clin Immunol; 105 [4], Seite 711-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10756220
Rankin, S. M.; Parthasarathy, S. und Steinberg, D.; (1991): Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages, J Lipid Res; 32 [3], Seite 449-56. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1906087
Rapoport, S.; Hartel, B. und Hausdorf, G.; (1984): Methionine sulfoxide formation: the cause of self-inactivation of reticulocyte lipoxygenase, Eur J Biochem; 139 [3], Seite 573-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6421581
Rapoport, S.; Hartel, B.; Schewe, T. und Kuhn, H.; (1986): Hydroperoxyfatty acids inactivate the reticulocyte lipoxygenase independently of a hydroperoxidase reaction, FEBS Lett; 202 [2], Seite 202-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3087777
Rapoport, S. M. und Schewe, T.; (1986): The maturational breakdown of mitochondria in reticulocytes, Biochim Biophys Acta; 864 [3-4], Seite 471-95. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3098292
Rapoport, S. M.; Schewe, T.; Wiesner, R.; Halangk, W.; Ludwig, P.; Janicke-Hohne, M.; Tannert, C.; Hiebsch, C. und Klatt, D.; (1979): The lipoxygenase of reticulocytes. Purification, characterization and biological dynamics of the lipoxygenase; its identity with the respiratory inhibitors of the reticulocyte, Eur J Biochem; 96 [3], Seite 545-61. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=111925
Rickert, K. W. und Klinman, J. P.; (1999): Nature of hydrogen transfer in soybean lipoxygenase 1: separation of primary and secondary isotope effects, Biochemistry; 38 [38], Seite 12218-28. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10493789
Rouzer, C. A.; Matsumoto, T. und Samuelsson, B.; (1986): Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities, Proc Natl Acad Sci U S A; 83 [4], Seite 857-61. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3006030
Rouzer, C. A. und Samuelsson, B.; (1985): On the nature of the 5-lipoxygenase reaction in human leukocytes: enzyme purification and requirement for multiple stimulatory factors, Proc Natl Acad Sci U S A; 82 [18], Seite 6040-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3929248
Rouzer, C. A. und Samuelsson, B.; (1986): The importance of hydroperoxide activation for the detection and assay of mammalian 5-lipoxygenase, FEBS Lett; 204 [2], Seite 293-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3089841
Salzmann, U.; Kuhn, H.; Schewe, T. und Rapoport, S. M.; (1984): Pentane formation during the anaerobic reactions of reticulocyte lipoxygenase. Comparison with lipoxygenases from soybeans and green pea seeds, Biochim Biophys Acta; 795 [3], Seite 535-42. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6433987
Sambrock, J.; Fritsch, E.F. und Maniatis, T.; (1989): Molecular Cloning: A laboratory manual., ;Cold Spring Harbor Laboratory Press;, ;Cold Spring Harbor, USA;.
Samuelsson, B.; Dahlen, S. E.; Lindgren, J. A.; Rouzer, C. A. und Serhan, C. N.; (1987): Leukotrienes and lipoxins: structures, biosynthesis, and biological effects, Science; 237 [4819], Seite 1171-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2820055
Sandstrom, P. A.; Tebbey, P. W.; Van Cleave, S. und Buttke, T. M.; (1994): Lipid hydroperoxides induce apoptosis in T cells displaying a HIV-associated glutathione peroxidase deficiency, J Biol Chem; 269 [2], Seite 798-801. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8288627
Scarrow, R. C.; Trimitsis, M. G.; Buck, C. P.; Grove, G. N.; Cowling, R. A. und Nelson, M. J.; (1994): X-ray spectroscopy of the iron site in soybean lipoxygenase-1: changes in coordination upon oxidation or addition of methanol, Biochemistry; 33 [50], Seite 15023-35. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7999760
Schewe, C.; Schewe, T. und Wendel, A.; (1994): Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione, Biochem Pharmacol; 48 [1], Seite 65-74. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8043032
Schewe, T.; (1995): Molecular actions of ebselen--an antiinflammatory antioxidant, Gen Pharmacol; 26 [6], Seite 1153-69. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7590103
Schewe, T.; Halangk, W.; Hiebsch, C. und Rapoport, S. M.; (1975): A lipoxygenase in rabbit reticulocytes which attacks phospholipids and intact mitochondria, FEBS Lett; 60 [1], Seite 149-52. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6318
Schewe, T.; Kroschwald, P.; Kroschwald, A.; Ludwig, P. und Kuhn, H.; (1990): The erythroid arachidonate 15-lipoxygenase in rat reticulocytes, Biomed Biochim Acta; 49 [2-3], Seite S42-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2386527
Schewe, T.; Kuhn, H. und Rapoport, S. M.; (1986): Positional specificity of lipoxygenases and their suitability for testing potential drugs, Prostaglandins Leukot Med; 23 [2-3], Seite 155-60. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3094029
Schewe, T.; Rapoport, S. M. und Kuhn, H.; (1986): Enzymology and physiology of reticulocyte lipoxygenase: comparison with other lipoxygenases, Adv Enzymol Relat Areas Mol Biol; 58, Seite 191-272. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3087141
Schilstra, M. J.; Veldink, G. A.; Verhagen, J. und Vliegenthart, J. F.; (1992): Effect of lipid hydroperoxide on lipoxygenase kinetics, Biochemistry; 31 [33], Seite 7692-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1510955
Schneider, C.; Keeney, D. S.; Boeglin, W. E. und Brash, A. R.; (2001): Detection and cellular localization of 12R-lipoxygenase in human tonsils, Arch Biochem Biophys; 386 [2], Seite 268-74. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11368351
Schnurr, K.; Belkner, J.; Ursini, F.; Schewe, T. und Kuhn, H.; (1996): The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products, J Biol Chem; 271 [9], Seite 4653-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8617728
Schwarz, K.; (2000): Untersuchungen zu den strukturellen und mechanistischen Ursachen der Positionsspezifität von Lipoxygenasen.;, ;Dissertation, Institut für Biologie, Mathematisch-Naturwissenschaftliche Fakultät I: Humboldt-Universität zu Berlin.
Schwarz, K.; Borngraber, S.; Anton, M. und Kuhn, H.; (1998): Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation, Biochemistry; 37 [44], Seite 15327-35. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9799493
Schwarz, K.; Walther, M.; Anton, M.; Gerth, C.; Feussner, I. und Kuhn, H.; (2001): Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis, J Biol Chem; 276 [1], Seite 773-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11027682
Schwenk, U.; Morita, E.; Engel, R. und Schroder, J. M.; (1992): Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid, J Biol Chem; 267 [18], Seite 12482-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1618754
Sendobry, S. M.; Cornicelli, J. A.; Welch, K.; Bocan, T.; Tait, B.; Trivedi, B. K.; Colbry, N.; Dyer, R. D.; Feinmark, S. J. und Daugherty, A.; (1997): Attenuation of diet-induced atherosclerosis in rabbits with a highly selective 15-lipoxygenase inhibitor lacking significant antioxidant properties, Br J Pharmacol; 120 [7], Seite 1199-206. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9105693
Serhan, C. N.; (1994): Eicosanoids in leukocyte function, Curr Opin Hematol; 1 [1], Seite 69-77. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9371262
Serhan, C. N.; (2002): Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution, Prostaglandins Other Lipid Mediat; 68-69, Seite 433-55. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12432935
Serhan, C. N.; Hamberg, M. und Samuelsson, B.; (1984): Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes, Proc Natl Acad Sci U S A; 81 [17], Seite 5335-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6089195
Serhan, C. N. und Sheppard, K. A.; (1990): Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro, J Clin Invest; 85 [3], Seite 772-80. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2155925
Shankaranarayanan, P.; Chaitidis, P.; Kuhn, H. und Nigam, S.; (2001): Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene, J Biol Chem; 276 [46], Seite 42753-60. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11509556
Shappell, S. B.; Boeglin, W. E.; Olson, S. J.; Kasper, S. und Brash, A. R.; (1999): 15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma, Am J Pathol; 155 [1], Seite 235-45. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10393855
Shappell, S. B.; Gupta, R. A.; Manning, S.; Whitehead, R.; Boeglin, W. E.; Schneider, C.; Case, T.; Price, J.; Jack, G. S.; Wheeler, T. M.; Matusik, R. J.; Brash, A. R. und Dubois, R. N.; (2001): 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells, Cancer Res; 61 [2], Seite 497-503. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11212240
Shen, J.; Herderick, E.; Cornhill, J. F.; Zsigmond, E.; Kim, H. S.; Kuhn, H.; Guevara, N. V. und Chan, L.; (1996): Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development, J Clin Invest; 98 [10], Seite 2201-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8941635
Shimizu, T.; Radmark, O. und Samuelsson, B.; (1984): Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid, Proc Natl Acad Sci U S A; 81 [3], Seite 689-93. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6322165
Shureiqi, I.; Wojno, K. J.; Poore, J. A.; Reddy, R. G.; Moussalli, M. J.; Spindler, S. A.; Greenson, J. K.; Normolle, D.; Hasan, A. A.; Lawrence, T. S. und Brenner, D. E.; (1999): Decreased 13-S-hydroxyoctadecadienoic acid levels and 15-lipoxygenase-1 expression in human colon cancers, Carcinogenesis; 20 [10], Seite 1985-95. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10506115
Sies, H.; (1994): Ebselen: a glutathione peroxidase mimic, Methods Enzymol; 234, Seite 476-82. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7808321
Sigal, E.; Craik, C. S.; Highland, E.; Grunberger, D.; Costello, L. L.; Dixon, R. A. und Nadel, J. A.; (1988): Molecular cloning and primary structure of human 15-lipoxygenase, Biochem Biophys Res Commun; 157 [2], Seite 457-64. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3202857
Sigal, E.; Grunberger, D.; Craik, C. S.; Caughey, G. H. und Nadel, J. A.; (1988): Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases, J Biol Chem; 263 [11], Seite 5328-32. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3356688
Sigal, E. und Nadel, J. A.; (1988): Arachidonic acid 15-lipoxygenase and airway epithelium. Biologic effects and enzyme purification, Am Rev Respir Dis; 138 [6 Pt 2], Seite S35-40. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3202520
Simon, T. C.; Makheja, A. N. und Bailey, J. M.; (1990): Relationship of vascular 15-lipoxygenase induction to atherosclerotic plaque formation in rabbits, Prostaglandins Leukot Essent Fatty Acids; 41 [4], Seite 273-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2077542
Skrzypczak-Jankun, E.; Amzel, L. M.; Kroa, B. A. und Funk, M. O., Jr.; (1997): Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme, Proteins; 29 [1], Seite 15-31. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9294864
Skrzypczak-Jankun, E.; Bross, R. A.; Carroll, R. T.; Dunham, W. R. und Funk, M. O., Jr.; (2001): Three-dimensional structure of a purple lipoxygenase, J Am Chem Soc; 123 [44], Seite 10814-20. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11686682
Sloane, D. L.; Browner, M. F.; Dauter, Z.; Wilson, K.; Fletterick, R. J. und Sigal, E.; (1990): Purification and crystallization of 15-lipoxygenase from rabbit reticulocytes, Biochem Biophys Res Commun; 173 [2], Seite 507-13. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2260964
Sloane, D. L.; Leung, R.; Barnett, J.; Craik, C. S. und Sigal, E.; (1995): Conversion of human 15-lipoxygenase to an efficient 12-lipoxygenase: the side-chain geometry of amino acids 417 and 418 determine positional specificity, Protein Eng; 8 [3], Seite 275-82. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7479689
Sloane, D. L.; Leung, R.; Craik, C. S. und Sigal, E.; (1991): A primary determinant for lipoxygenase positional specificity, Nature; 354 [6349], Seite 149-52. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1944593
Smith, R. L. und Weidemann, M. J.; (1980): Reactive oxygen production associated with arachidonic acid metabolism by peritoneal macrophages, Biochem Biophys Res Commun; 97 [3], Seite 973-80. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6781503
Solomon, E. I.; Zhou, J.; Neese, F. und Pavel, E. G.; (1997): New insights from spectroscopy into the structure/function relationships of lipoxygenases, Chem Biol; 4 [11], Seite 795-808. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9384534
Spanbroek, R.; Stark, H. J.; Janssen-Timmen, U.; Kraft, S.; Hildner, M.; Andl, T.; Bosch, F. X.; Fusenig, N. E.; Bieber, T.; Radmark, O.; Samuelsson, B. und Habenicht, A. J.; (1998): 5-Lipoxygenase expression in Langerhans cells of normal human epidermis, Proc Natl Acad Sci U S A; 95 [2], Seite 663-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9435249
Spindler, S. A.; Sarkar, F. H.; Sakr, W. A.; Blackburn, M. L.; Bull, A. W.; LaGattuta, M. und Reddy, R. G.; (1997): Production of 13-hydroxyoctadecadienoic acid (13-HODE) by prostate tumors and cell lines, Biochem Biophys Res Commun; 239 [3], Seite 775-81. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9367845
Su, C. und Oliw, E. H.; (1998): Manganese lipoxygenase. Purification and characterization, J Biol Chem; 273 [21], Seite 13072-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9582345
Sun, D. und Funk, C. D.; (1996): Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein, J Biol Chem; 271 [39], Seite 24055-62. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8798642
Sun, D.; McDonnell, M.; Chen, X. S.; Lakkis, M. M.; Li, H.; Isaacs, S. N.; Elsea, S. H.; Patel, P. I. und Funk, C. D.; (1998): Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment, J Biol Chem; 273 [50], Seite 33540-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9837935
Suzuki, H.; Kishimoto, K.; Yoshimoto, T.; Yamamoto, S.; Kanai, F.; Ebina, Y.; Miyatake, A. und Tanabe, T.; (1994): Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase, Biochim Biophys Acta; 1210 [3], Seite 308-16. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8305485
Takahashi, Y.; Glasgow, W. C.; Suzuki, H.; Taketani, Y.; Yamamoto, S.; Anton, M.; Kuhn, H. und Brash, A. R.; (1993): Investigation of the oxygenation of phospholipids by the porcine leukocyte and human platelet arachidonate 12-lipoxygenases, Eur J Biochem; 218 [1], Seite 165-71. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8243462
Takahashi, Y.; Reddy, G. R.; Ueda, N.; Yamamoto, S. und Arase, S.; (1993): Arachidonate 12-lipoxygenase of platelet-type in human epidermal cells, J Biol Chem; 268 [22], Seite 16443-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8344930
Takahashi, Y.; Ueda, N. und Yamamoto, S.; (1988): Two immunologically and catalytically distinct arachidonate 12-lipoxygenases of bovine platelets and leukocytes, Arch Biochem Biophys; 266 [2], Seite 613-21. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3190246
Takasago, T.; Peters, E. E.; Graham, D. I.; Masayasu, H. und Macrae, I. M.; (1997): Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion, Br J Pharmacol; 122 [6], Seite 1251-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9401794
Tang, D. G.; Chen, Y. Q. und Honn, K. V.; (1996): Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis, Proc Natl Acad Sci U S A; 93 [11], Seite 5241-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8643560
Tang, D. G. und Honn, K. V.; (1997): Apoptosis of W256 carcinosarcoma cells of the monocytoid origin induced by NDGA involves lipid peroxidation and depletion of GSH: role of 12-lipoxygenase in regulating tumor cell survival, J Cell Physiol; 172 [2], Seite 155-70. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9258337
Tang, D. G.; Renaud, C.; Stojakovic, S.; Diglio, C. A.; Porter, A. und Honn, K. V.; (1995): 12(S)-HETE is a mitogenic factor for microvascular endothelial cells: its potential role in angiogenesis, Biochem Biophys Res Commun; 211 [2], Seite 462-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7540838
Tang, S.; Bhatia, B.; Maldonado, C. J.; Yang, P.; Newman, R. A.; Liu, J.; Chandra, D.; Traag, J.; Klein, R. D.; Fischer, S. M.; Chopra, D.; Shen, J.; Zhau, H. E.; Chung, L. W. und Tang, D. G.; (2002): Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells, J Biol Chem; 277 [18], Seite 16189-201. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11839751
Tappel, A.L.; (1953): Linoleate oxidation catalysts occuring in animal tissues., Food Res; 18, Seite 104-108.
Theorell, H.; Holman, R.T. und Akeson, A; (1947): Cristalline Lipoxydase., Acta Chem Scand; 1, Seite 571-576.
Thiele, B. J.; Andree, H.; Hohne, M. und Rapoport, S. M.; (1982): Lipoxygenase mRNA in rabbit reticulocytes. Its isolation, characterization and translational repression, Eur J Biochem; 129 [1], Seite 133-41. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6819138
Thomas, C. E. und Jackson, R. L.; (1991): Lipid hydroperoxide involvement in copper-dependent and independent oxidation of low density lipoproteins, J Pharmacol Exp Ther; 256 [3], Seite 1182-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2005580
Thomas, J. P.; Geiger, P. G. und Girotti, A. W.; (1993): Lethal damage to endothelial cells by oxidized low density lipoprotein: role of selenoperoxidases in cytoprotection against lipid hydroperoxide- and iron-mediated reactions, J Lipid Res; 34 [3], Seite 479-90. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8468531
Thomas, J. P.; Maiorino, M.; Ursini, F. und Girotti, A. W.; (1990): Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides, J Biol Chem; 265 [1], Seite 454-61. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2294113
Timar, J.; Silletti, S.; Bazaz, R.; Raz, A. und Honn, K. V.; (1993): Regulation of melanoma-cell motility by the lipoxygenase metabolite 12-(S)-HETE, Int J Cancer; 55 [6], Seite 1003-10. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8253518
Trebus, F.; Heydeck, D.; Schimke, I.; Gerth, C. und Kuhn, H.; (2002): Transient experimental anemia in cholesterol-fed rabbits induces systemic overexpression of the reticulocyte-type 15-lipoxygenase and protects from aortic lipid deposition, Prostaglandins Leukot Essent Fatty Acids; 67 [6], Seite 419-28. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12468263
Turk, J.; Maas, R. L.; Brash, A. R.; Roberts, L. J., 2nd und Oates, J. A.; (1982): Arachidonic acid 15-lipoxygenase products from human eosinophils, J Biol Chem; 257 [12], Seite 7068-76. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6806264
Ueda, N. und Yamamoto, S.; (1988): The 6R-oxygenase activity of arachidonate 5-lipoxygenase purified from porcine leukocytes, J Biol Chem; 263 [4], Seite 1937-41. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3338999
Ulbricht, B.; Hagmann, W.; Ebert, W. und Spiess, E.; (1996): Differential secretion of cathepsins B and L from normal and tumor human lung cells stimulated by 12(S)-hydroxy-eicosatetraenoic acid, Exp Cell Res; 226 [2], Seite 255-63. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8806429
Ullrich, V.; Weber, P.; Meisch, F. und von Appen, F.; (1996): Ebselen-binding equilibria between plasma and target proteins, Biochem Pharmacol; 52 [1], Seite 15-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8678900
van Leyen, K.; Duvoisin, R. M.; Engelhardt, H. und Wiedmann, M.; (1998): A function for lipoxygenase in programmed organelle degradation, Nature; 395 [6700], Seite 392-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9759730
Van Os, C. P.; Rijke-Schilder, G. P.; Van Halbeek, H.; Verhagen, J. und Vliegenthart, J. F.; (1981): Double dioxygenation of arachidonic acid by soybean lipoxygenase-1. Kinetics and regio-stereo specificities of the reaction steps, Biochim Biophys Acta; 663 [1], Seite 177-93. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6783108
Vanderhoek, J. Y.; Bryant, R. W. und Bailey, J. M.; (1980): Inhibition of leukotriene biosynthesis by the leukocyte product 15-hydroxy-5,8,11,13-eicosatetraenoic acid, J Biol Chem; 255 [21], Seite 10064-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6253463
Verhagen, J.; Veldink, G. A.; Egmond, M. R.; Vliegenthart, J. F.; Boldingh, J. und van der Star, J.; (1978): Steady-state kinetics of the anaerobic reaction of soybean lipoxygenase-1 with linoleic acid and 13-L-hydroperoxylinoleic acid, Biochim Biophys Acta; 529 [3], Seite 369-79. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=96861
Watanabe, T. und Haeggstrom, J. Z.; (1993): Rat 12-lipoxygenase: mutations of amino acids implicated in the positional specificity of 15- and 12-lipoxygenases, Biochem Biophys Res Commun; 192 [3], Seite 1023-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8507177
Watanabe, T.; Medina, J. F.; Haeggstrom, J. Z.; Radmark, O. und Samuelsson, B.; (1993): Molecular cloning of a 12-lipoxygenase cDNA from rat brain, Eur J Biochem; 212 [2], Seite 605-12. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8444196
Webb, E.C.; (1992): Recommendations of the Nomenclature Commitee of the International Union of Biochemistry and Molecular Biology on the nomenclature and classifications of enzymes., Enzyme Nomenclature;, ;Acad Press;, ;San Diego;.
Wiesner, R.; Suzuki, H.; Walther, M.; Yamamoto, S. und Kuhn, H.; (2003): Suicidal inactivation of the rabbit 15-lipoxygenase by 15S-HpETE is paralleled by covalent modification of active site peptides, Free Radic Biol Med; 34 [3], Seite 304-15. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12543246
Williams, S. E.; Inoue, I.; Tran, H.; Fry, G. L.; Pladet, M. W.; Iverius, P. H.; Lalouel, J. M.; Chappell, D. A. und Strickland, D. K.; (1994): The carboxyl-terminal domain of lipoprotein lipase binds to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor (LRP) and mediates binding of normal very low density lipoproteins to LRP, J Biol Chem; 269 [12], Seite 8653-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7510694
Woods, J. W.; Coffey, M. J.; Brock, T. G.; Singer, II und Peters-Golden, M.; (1995): 5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation, J Clin Invest; 95 [5], Seite 2035-46. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7738170
Yamamoto, S.; (1989): Mammalian lipoxygenases: molecular and catalytic properties, Prostaglandins Leukot Essent Fatty Acids; 35 [4], Seite 219-29. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2497473
Yamamoto, S.; (1991): "Enzymatic" lipid peroxidation: reactions of mammalian lipoxygenases, Free Radic Biol Med; 10 [2], Seite 149-59. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1901823
Yamamoto, S.; (1992): Mammalian lipoxygenases: molecular structures and functions, Biochim Biophys Acta; 1128 [2-3], Seite 117-31. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1420284
Yamashita, H.; Nakamura, A.; Noguchi, N.; Niki, E. und Kuhn, H.; (1999): Oxidation of low density lipoprotein and plasma by 15-lipoxygenase and free radicals, FEBS Lett; 445 [2-3], Seite 287-90. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10094474
Yla-Herttuala, S.; Rosenfeld, M. E.; Parthasarathy, S.; Glass, C. K.; Sigal, E.; Witztum, J. L. und Steinberg, D.; (1990): Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions, Proc Natl Acad Sci U S A; 87 [18], Seite 6959-63. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1698286
Yokoyama, C.; Shinjo, F.; Yoshimoto, T.; Yamamoto, S.; Oates, J. A. und Brash, A. R.; (1986): Arachidonate 12-lipoxygenase purified from porcine leukocytes by immunoaffinity chromatography and its reactivity with hydroperoxyeicosatetraenoic acids, J Biol Chem; 261 [35], Seite 16714-21. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=3782139
Yoshimoto, T.; Suzuki, H.; Yamamoto, S.; Takai, T.; Yokoyama, C. und Tanabe, T.; (1990): Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes, Proc Natl Acad Sci U S A; 87 [6], Seite 2142-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2315307
Yoshimoto, T.; Suzuki, H.; Yamamoto, S.; Takai, T.; Yokoyama, C. und Tanabe, T.; (1991): Cloning and expression of arachidonate 12-lipoxygenase cDNA from porcine leukocytes, Adv Prostaglandin Thromboxane Leukot Res; 21A, Seite 29-32. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1825555
Zhang, Y. Y.; Radmark, O. und Samuelsson, B.; (1992): Mutagenesis of some conserved residues in human 5-lipoxygenase: effects on enzyme activity, Proc Natl Acad Sci U S A; 89 [2], Seite 485-9. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1731317
| © Die inhaltliche Zusammenstellung und Aufmachung dieser Publikation sowie die elektronische Verarbeitung sind urheberrechtlich geschützt. Jede Verwertung, die nicht ausdrücklich vom Urheberrechtsgesetz zugelassen ist, bedarf der vorherigen Zustimmung. Das gilt insbesondere für die Vervielfältigung, die Bearbeitung und Einspeicherung und Verarbeitung in elektronische Systeme. | ||
| XDiML DTD Version 4.0 | Zertifizierter Dokumentenserver der Humboldt-Universität zu Berlin | HTML-Version erstellt am: 05.01.2007 |