[Seite 69↓]


Adami H O, Lund E, Bergstrom R, Meirik O. Cigarette smoking, alcohol consumption and risk of breast cancer in young women. Br. J Cancer. 58: 832-837 (1988).

Adami H, Bergstrom R, Lund E, et al. Absence of association between reproductive variables and the risk of breast cancer in young women in Sweden and Norway. Br J Cancer. 62: 122 (1990)

Agundez J A G., Ladero J M, Olivera M. Genetic Analysis of the Arylamine N-Acetyltransferase Polymorphism in Breast Cancer Patients. Oncology. 52: 7-11 (1995).

Agundez J A G, Olivera M, Martinez C, Ladero J M, Benitez J. Identification and prevalence study of 17 allelic variants of the human NAT2 gen in a white population. Parmacogenetics. 6: 109-140 (1996).

Allaben W T, Weeks C E, Weis C E, Burger G T, King C M. Rat mammary gland carcinogenesis after local injection of N-hydroxy-N-acyl-2-aminofluorenes: relationship to metabolic activation. Carcinogenesis. 3: 233-240 (1982).

Allaben W T, Weis C C, Fullerton N F, Beland F A. Formation and persistence of DNA adducts from the carcinogen N-hydroxy-2-acetylaminofluorene in rat mammary gland in vivo. Carcinogenesis. 4: 1067-1070 (1983).

Ambrosone C B, Freudenheim Jo L, Graham S: Cigarette Smoking, N-Acetyltransferase 2 Genetic Polymorphisms, and Breast Cancer Risk. JAMA. Vol.276 No.18: 1494-1501 (1996).

Ambrosone CB, Freudenheim Jo L, Sinha R, Graham S, Marshall J R, Vena J E, Laughlin R, Nemoto T, Shields P G. Breast Cancer Risk, Meat Consumption And N-Acetyltransferase (NAT2) Genetic Polymorphism. Int. J. Cancer. 75: 825-830 (1998).

Anderson D. Genetic study of breast cancer: identification of a high risk group. Cancer. 34: 1090 (1974)

[Seite 70↓]

Baron J, Newcomb P, Longnecker M, Mittendorf R, Storer B, Clapp R, Bogdan G; Yuen G. Cigarette smoking and breast cancer. Cancer Epidemiol. Biomark. Prev. 5: 399-405 (1996).

Baron JA, Byers T, Greenberg ER, Cummings KM, Swanson M. Cigarette smoking in women with cancers of the breast and reproductive organs. J Natl Cancer Inst. 77: 677-680 (1986)

Bell D A, Taylor J A, Butler M A, Stephens E A, Wiest J, Brubaker L H, Kadlubar F F, Lucier G W. Genotype/phenotype discordance for human arylamine N-Acetyltransferase (NAT2) reveals a new slow-Acetylator allel common in African-Americans. Cacinogenesis. 14: 1689-1692 (1993).

Bernstein L, Ross R, Lobo R. The effects of moderate physical activity on menstrual cycle patterns in adolescence: implications for breast cancer prevention. Br J Cancer. 55: 681 (1987).

Blum M, Grant M D M, McBride W, Heim M, Meyer U A, Human arylamine N-Acetyl-transferase genes: isolation, chromosomal localization and functional expression. DNA Cell Biol. 9: 193-203 (1990)

Blum M, Demierre A, Grant M D M, Heim M, Meyer U A. Molecular mechanism of slow Acetylation of drugs and carcinogens in humans. Proc Natl Acad Sci USA 88: 5237-5241 (1991).

Bluman LG, Rimer BK, Berry DA, et al. Attitudes, knowledge and risk perceptions of women with breast and ovarian cancer considering testing for BRCA1 and BRCA2. J Clin Oncol. 17: 1040 (1999).

Bouchardy C, Mitrunen K, Wikman H. N-Acetyltransferase NAT1 and NAT2 genotypes and lung cancer risk. Pharmacogenetics. Vol 8: 291-298 (1998).

Brinton I, Hoover R, Fraumeni J. Reproductive factors in aetiology of breast cancer. Br J Cancer. 47: 757 (1983)

[Seite 71↓]

Brinton L A, Schairer C, Stanford J L, Hoover R N. Cigarette smoking and breast cancer. Am J Epidemiol. 123: 614-622 (1986)

Brockmöller J, Cascorbi I, Kerb R, Roots I. Combined analysis of inherited polymorphism in arylamine N-Acetyltransferase 2, glutathione S-transferase M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk: Cancer Res. 56: 3915-3925 (1996).

Brownson R C, Blackwell C W, Pearson D K, Reynolds R D, Richens J W Jr, Papermaster B W. Risk of breast cancer in relation to cigarette smoking. Arch Intern Med. 148: 140-144 (1988)

Buell P. Changing incidence of breast cancer in Japanese-American women. J Natl Cancer Inst. 51: 1479-1483 (1973).

Bulovskaya, L N, Kripkin R G, Bochina T A, Shipkova A A, Pavlova M V. Acetylator phenotype in patients with breast cancer. Oncology 35: 185-188 (1978)

Capstur S, Potter J, Sellers T, et al. Increased risk of breast cancer with alcoholic con-sumption in postmenopausal women. Am J Epidemiol. 136: 1221 (1992)

Capstur S, Morrow M, Sellers T. Hormone replacement therapy and risk of breast cancer with a favorable hiostology: results of the Iowa Womens`Health Study. JAMA. 281: 2091 (1999).

Cascorbi I, Drakoulis N, Bockmöller J, Maurer A, Sperling K, Roots I. Arylamine-N-Acetylransferase (NAT2) mutations and their allelic linkage in unrelated Caucasians individuals: correlation with Phenotypic Activity. Am. J. Hum. Genet. 57: 581-592 (1995).

Cascorbi I, Bockmöller J, Mrozokiewicz P M, Bauer S, Loddenkemper R, Roots I. Homozygous Rapid Arylamine N-Acetyltransferase (NAT2) Genotypes as Susceptibility Factors for Lung Cancer. Cancer Res. 56: 3961-3966 (1996).

[Seite 72↓]

Cascorbi I, Brockmöller J, Bauer S, Reum T, Roots I. NAT2*12A (803A->G) codes for rapid arylamine N-acetylation in humans. Pharmacogenetics. 6: 257-259 (1996).

Cascorbi I, Bockmöller J, Müller A, Roots I. Arylamine-N-Acetyltransferase activity in man. Drug Metabol. Rev. 31: 489-507 (1999).

Cauley JA, Lucas FL, Kuller LH, et al. Elevated serum estradiol and testosteron concentrations are associated with high risk for breast cancer. Ann Intern Med. 130: 270 (1999).

Chu S Y, Stroup N E, Wingo P A, Lee N C, Peterson H B, Gwinn M L. Cigarette smoking and the risk of breast cancer. Am J Epidemiol. 131: 244-253 (1990).

Claus EB, Schildkraut JM, Thompson WE, Risch NJ. The genetic attributable risk of breast and ovarian cancer. Cancer. 77: 2318 (1996).

Collaborative Group on Hormonal Factors in Breast Cancer. Breast cancer and hormone replacement therapy: collaborative reanalyses of data from 51 epidemiological studies of 52.705 women with breast cancer and 108.411 women without breast cancer. Lancet. 350: 1047 (1997).

Deguchi T, Mashimo M, Suzuki T. Correlation between Acetylator phenotypes and genotypes of polymorphic arylamine N-Acetyltransferase in human liver. J. Biol. Chem. 265: 12757-12760 (1990)

Delomenie C, Sica D, Grant D M, Krishnamoorthy R, and Dupret J M. Pharmaconetics. 6: 177-185 (1996).

De Vita T, Hellman S, Rosenberg S A (Hrsg.): Cancer Principles and Practice of Oncology. Fifth Edition. Lippincott-Raven Publishers. Philadelphia (2001).

Doll R, Gray R, Hafner B, Peto R. Mortality in relation to smoking: 22 years´ observationon female British doctors. BMJ. 280: 967-971 (1980)

[Seite 73↓]

Drodz M, Giereck T, Jendryczko A, Pilch J, Piekarska J. N- Acetyltransferase phenotype of patients with cancer of the larynx. Neoplasma 34: 481-483 (1987).

Dunning A M, Healey C S, Pharoah P D , Teare MD, Ponder B A, Bruce A J. Easton D F. A systematic review of genetic polymorphisms and breast cancer risk. Cancer Epidemiology Biomarkers Prev. Vol. 8: 843-854 (1999).

Dupont W, Page D. Risk factors for breast cancer in women with proliferative breast desease. N Engl J Med. 312 : 146 (1985).

Dupont W, Page D, Parl F, et al. Estrogen replacement therapy in women with a history of proliferative breast desease. Cancer. 85: 1277 (1999).

Eldridge S R, Gould M N, Butterworth B E. Genotoxity of enviromental agents in human mammary epithelial cells. Cancer Res. 52: 5617-5621 (1994).

Evans D A P, Eze L C, Whibley E J. The associaton of the slow Acetylator phenotype with bladder cancer. J. Med. Genet. 20: 330-333 (1993).

Evans D A P. N-Acetyltransferase. In: Kalow, W. (Hrsg.): Pharmacogenetics of drug metabolism. Pergamon Press, New Yorck. 95-178 (1992).

Ewartz M. Smoking and breast cancer risk in Denmark. Cancer Causes Controll. 1: 31-37 (1990)

Field N A, Baptiste M S, Nasca P C, Metzger B B. Cigarette smoking and breast cancer. Int J Epidemiol. 21: 842-848 (1992)

Fretland, A.J., Leff, M.A., Doll, M.A., and Hein, D.W. Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms. Pharmacogenetics, 11: 207-215, 2001.

Friedenreich C, Howe G, Miller A, et al. A cohort study of alcolhol consumption and risk of breast cancer. Am J Epidemiol. 137: 512 (1993).

[Seite 74↓]

Garfinkel L, Bofetta P, Stellman S. Alcohol and breast cancer: a cohort study. Prev. 17: 686 (1988)

Gil J P, Lechner M C. Increased frequency of wild-type arylamine-N-Acetyltransferase allele NAT2*4 homozygotes in Portuguese partients with colorectal cancer. Carcino-genesis. 19: 37-41 (1998).

Grant D M, Mörike K, Eichelbaum M, Meyer U A. Acetylation pharmacogenetics: The slow Acetylator phenotype is caused by decreased or absent arylamine N-Acetyltransferase in human liver. J. Clin. Invest. 85: 968-972 (1990).

Grant D M, Blum M, Demierre A, Meyer U A. Polymorphisms of N-Acetyltransferase genes. Xenobiotica.,: Vol.22, Nos 9/10 1073-1081 (1992).

Grant D M : Molecular genetics of the N-Acetyltransferases. Pharmacogenetics. 3: 45-50 (1993)

Greiling H; Gressner AM. Lehrbuch der Klinischen Chemie. S. 564. Schattauer (1995).

Hadjimichael O, Boyle C, Meigs J. Abortion before first live birth and risk of breast cancer. Br J Cancer. 53: 283 (1986).

Hankinson S, Willet W, Manson J, et al. Alcohol, height, and adiposity in relation to estrogen and prolactin levels in postmenopausal women. J Natl Cancer Inst. 87: 1297 (1994).

Hankinson S, Colditz G, Manson J, et al. A prospective study of oral contraceptive use and risk of breast cancer (Nurses` Health Study, United States). Cancer Causes Control. 8: 65 (1997).

Hankinson S, Willet WC, Manson J, et al. Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women. J Natl Cancer Inst. 90: 1292 (1998).

[Seite 75↓]

Hancock SL, Tucker MA, Hoppe RT. Breast cancer after treatment of Hodgkin`s desease. JNCI. 85(1): 25-31 (1993).

Healey B. BRCA-genes bookmaking, fortune telling, and medical care. N Engl J Med. 336: 1448-1449 (1997).

Hein D W, Doll M, Rustan T, Gray K, Feng Y, Ferguson R, Grant D. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 Acetyltransferases. Carcinogenesis (Lond.). 14: 1633-1638 (1993)

Hein D W, Ferguson R J, Doll M, Rustan T, Gray K. Molecular genetics of human poly-morphic N-Acetyltransferase - enzymatic analyses of 15 recombinant wild-type, mutant and chimeric NAT2 alloenzymes. Hum. Molec. Genetics. 3: 729-734 (1994)

Hein, DW, Grant, DM, and Sim, E. Update on consensus arylamine N-acetyltransfe-rase gene nomenclature. Pharmacogenetics, 10: 291-292, (2000).

Helzlsouer KJ. Epidemiology, prevention, and early detection of breast cancer. Curr Opin Oncol. 2: 343 (1995).

Henderson B, Ross R, Bernstein L. Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res. 48: 246 (1988)

Henderson B, Ross R, Ludd H. Do regulate ovulary cycles increase breast cancer risk? Cancer. 45: 1206 (1985)

Henning S, Cascorbi I, Münchow B, Jahnke V, Roots I. Association of arylamine N-acetyltransferase NAT1 and NAT2 genotypes to laryngeal cancer risk. Pharmacogenetics. 9: 103-111 (1999).

Hiatt R A, Fireman B H. Smoking, menopause, and breast cancer. J Natl Cancer Inst. 76: 833-838 (1986)

[Seite 76↓]

Hiatt R A, Klatzky A L, Armstrong M A. Alcoholic consumption and the risk of breast cancer in a pre-paid health plan. Cancer Res. 48: 2284-2287 (1988)

Hickman D, Sim E. N-Acetyltransferase polymorphism - comparison of phenotype and genotype in humans. Biochem. Pharmacol. 42: 1007-1014 (1991).

Hickman D, Risch A, Buckle V, Spurr N K, Jeremiah S J, McCarthy A, Sim E. Chromo-somal localisation of human genes for arylamine N-Acetyltransferase. Biochem J. 297: 441-445 (1994).

Hildreth N, Shore L, Dvoretsky P. The risk of breast cancer after irradiation of the thymus in infancy. N Engl J Med. 321: 146 (1989)

Hoecksema MJ, Law C. Cancer mortality rates fall: a turning point for the nation. JNCI 88(23): 1706-1707 (1996).

Howe H, Senie R, Bzsuch H, et al. Early abortion and breast cancer risk in women under 40. Int J Epidemiol. 18: 300 (1989)

Holmes M, Hunter D, Coldtz G, et al.. Association of dietary intake of fat and fatty acids with risk of breast cancer. JAMA. 281: 914 (1999).

Huang Z, Hankinson SE, Golditz GA, et al. Dual effects of weight and weight gain on breast cancer risk. JAMA. 278: 1407 (1997).

Huang, C-S, Chern H-D, Shen C-Y, Hsu S-M, Chang K-J. Association between N-Acetyltransferase (NAT2) genetic polymorphism and developement of breast cancer in postmenopausal chinese women in Taiwan, an area of great increase in breast cancer incidence. Int. J. Cancer. 82: 175-179 (1999).

Hunter D J, Hankison S E, Hough H. A prospective study of NAT2 Acetylation genotype, cigarette smoking, and risk of breast cancer. Carcinogenesis. Vol.18, No.11: 2127-2132 (1997).

[Seite 77↓]

Hunter D, Spiegelman D, Adami H, et al. Cohort studies of fat intake and the risk of breast cancer. A pooled analysis. N Engl J Med. 334: 356 (1996)

Hunter D, Willet W C. Nutrition and breast cancer. Cancer causes Control. 7: 56-68 (1996).

Huober J, Bertram B, Petru E. Metabolism of debrisoquine and susceptibility to breast cancer. Breast Cancer Research and Treatment. Vol. 18: 43-48. (1991).

Ilett K F, Ingram D M, Carpenter D S, Teitel C H, Lang A P, Kadlupar F F. Expression of monomorphic and polymorphic N-Acetyltransferases in human colon. Biochem. Parmacol. 47: 914-917 (1994).

Jarvinen R, Knekt P, Seppanen R , Teppo L. Diet and breast cancer risk in a cohort of Finnish women. Cancer Lett. 114: 251-253 (1997).

Josephy P D. The role of peroxidase-catalyzed activation of aromatic amines in breast cancer. Mutagenesis. 11: 3-7 (1996).

Kelsey JL, Gammon MD, John EM. Reproductive factors and breast cancer. Epidemimiol Rev. 15: 233 (1993).

King C M, Traub N R, Lortz Z M, Thissen M R. Metabolic activation of arylhydroxamine acids by N-O-acetyltransferase of rat mammary gland. Cancer Res. 39: 3369-3372 (1979).

Kinlen L. Meat and fat consumption and cancer mortality: a study of strict religious orders in Britain. Lancet. 1: 946 (1982)

Ladero R M, Benitez J, Jara C. Polymorphic Oxidation of Debrisoquine in Women with Breast Cancer. Oncology: 48: 107-110 (1991).

Ladero R M, Fernandez M J, Palmeiro R. Hepatic Acetylator Polymorphism in Breast Cancer Patients. Oncology. 44: 341-344 (1987).

[Seite 78↓]

Lerman C, Lustbader E, Rimer B, et al. Effects of individualized breast cancer risk counseling: a randomized trial. J Natl Cancer Inst. 87: 286 (1995).

Levi F, Vecchia C, Luccini F et al.. Cancer mortality in Europe. 1990-1992. Eur. J. Cancer Prev. 4: 389-417 (1995).

Li D, Wang M, Dhingra K, Hittleman W M. Aromatic DNA adducts in adjecent tissues of breast cancer patients: clues to breast cancer etiology. Cancer Res. 56: 287-293 (1996).

Lin H J, Han C Y, Lin B K, Hardy S. Slow Acetylator mutations in the human polymorphic N-Acetyltransferase gene in 786 Asians, blacks, Hispanics and whites - application to metabolic epidemiology: Am. J. Hum. Genet. 52: 827-834 (1993).

Lin H J. Smokers and breast cancer: "chemical individuality" and cancer pre-disposition. J. Am. Med. Ass. 276: 1511-1512 (1996)

London S J, Colditz G A, Stampfer M J, Willet W C, Rosner B A, Speizer F E. Prospective study of smoking and the risk of breast cancer. J Natl. Cancer Inst. 81: 1625-1631 (1989)

Longnecker M, Berlin J, Orza M. A meta-analysis of alcohol consumption in relation to breast cancer risk. JAMA. 260: 642 (1988)

Lower G M, Nilsson T, Nelson C E, Wolf H, Gamsky T E, Bryan G T. N-Acetyltransferase phenotype and risk in urinary bladder cancer. Approaches in molecular epidemiology. Preliminary results in Sweden and Denmark: Environ. Health Perspect. 29: 71-79. (1979)

MacMahon B, Cole P, Lin T. Age at first birth and breast cancer risk. Bull WHO. 43: 209 (1970)

MacMahon B, Cole P, Brown J. Etiology of human breast cancer: a review. J Natl Cancer Inst. 50: 21 (1973)

[Seite 79↓]

MacMahon B, Trichopoulos D, Brouwn J. Age at menarche, probability of ovulation and breast cancer risk. Int J Cancer. 29: 12 (1982)

McMichael A, Giles G. Cancer in migrants to Australia: extending descriptive epidemio-logical data. Cancer Res. 48: 751 (1988).

Madigan M P, Ziegler R G, Benichou J, Byrne C, Hoover R N: Proportion of breast cancer cases in the Unites States explained by well established risk factors. J.Nat..Cancer Inst. 87: 1681-1685 (1995).

Maier H, Dietz A, Zielinski D, Jünemann K H, Heller W D. Risikofaktoren bei Plat-tenepithelkarzinomen der Mundhöhle, des Oropharynx, des Hypopharynx und des Larynx. Dtsch. med. Wschr. 115: 843-850 (1990)

Maier H, Dietz A, Gewelke U Seitz H K, Heller W D. Tabak- und alkoholassoziiertes Krebsrisiko im Bereich des oberen Atmungs- und Verdauungstraktes. Laryngo-Rhino-Otol. 69: 505-511 (1990)

Malone K, Daling J, Weiss N. Oral contraceptives in relation to breast cancer. Epidemiol Rev. 15: 80 (1993)

Martinez C, Agundez J A G, Olivera M, Martin R, Ladero J M, Benitez J. Lung cancer and mutations at the polymorphic NAT2 gene locus. Pharmacogenetics. 5: 207-214 (1995).

Meara J, McPherson K, Roberts M, Jones L, Vessey M. Alcohol, cigarette smoking and breast cancer. Br J Cancer. 60: 70-73 (1989)

Millikan R C, Pittman G S, Newman B. Cigarette Smoking, N-Acetyltransferase 1 and 2, and Breast Cancer Risk. Cancer Epidemiology, Biomarkers & Prevention, Vol. 7: 371-378 (1998).

[Seite 80↓]

Miller A; Howe G, Sherman G. Mortality from breast cancer after irradiation during thorascopic examinations in patients being treated for tuberculosis. N. Engl J Med. 321: 1285 (1989).

Molgavkar S, Day N, Stevens R. Two stage model for carcinogenesis: epidemiology of breast cancer in females. J Natl Cancer Inst. 54: 559 (1989)

Mommsen, S.; Barfold, N M, Aagaard, J. N-Acetyltransferase phenotypes in the urinary bladder carcinogenesis of a low-risk population: Carcinogenesis. 6: 199-201 (1985).

Morabia A; Bernstein M; Heritier S; Khatachatnan N. Relation of breast cancer with passive and active exposure to tobacco smoke. Am. J. Epidemiol. 143: 918-928 (1996).

Mrozikiewicz P M, Cascorbi I, Brockmöller J, Roots I: Determination and allelic allocation of seven nucleotide transitions within the arylamine N-acetyltransferase gene in the Polish population. Clin Pharmacol Ther. 59: 376-382 (1996).

Madigan M P, Ziegler R G, Benichou J, Byrne C, Hoover R N. Proportion of breast cancer cases in the United States explained by well established risk factors. J. Nat. Cancer Inst. 87: 1681-1685 (1995).

Melbye M, Wohlfahrt J, Olsen J. Induced abortion and the risk of breast cancer. N Engl J Med. 336: 81 (1997)

Morabia A, Bernstein M, Heritier S, Khatchatanan N. Relation of breast cancer with passive and active exposure to tobacco smoke. Am. J. Epidemiol. 143: 918-928 (1996)

Nebert D. Polymorphisms in drug-metabolism enzymes: what is their clinical relevance and why do they exist? Am. J. Hum. Gen. 60: 265-271 (1997)

Newcomb P, Storer B, Longnecker M, et al. Lactation and a reduced risk of premeno-pausal breast cancer. N Engl J Med. 330: 81 (1994)

[Seite 81↓]

Newcomb P, Storer B, Longnecker M, et al. Pregnancy termination in relation to risk of breast cancer. JAMA.. 275: 283 (1996).

Nissen-Meyer R. Primary breast cancer: the effect of primary ovarian irradiation. Ann Oncol. 2: 343 (1991).

O´Connel DL, Hulka BS, Chambles LE, Wilkinson WE, Deubner DC. Cigarette smoking, alcohol consumption, and breast caner risk. J Natl Cancer Inst. 78: 229-234 (1987).

Ottman R, King M, Pike M, et al. Practical guide to estimating risk in familial breast cancer. Lancet. 2: 556 (1983).

Palmer JR, Rosenberg L, Clarke E, et al. Breast cancer and cigarette smoking: a hypo-thesis. Am J Epidemiol. 134: 1-13 (1991)

Perera FP, Estabrook A, Hewer A, et al. Carcinogenic DNA-adducts in human breast tissue. Cancer Epidemiol Biomarkers Prev. 4: 233-238 (1995).

Petrakis NL, Gruenke LD, Beelen TC, Castagnoli N Jr, Craig JC. Nicotine in breast fluid of nonlactating women. Science. 199: 303-304 (1978)

Petrakis NL, Maack CA, Lee RR, Lyon M. Mutagenic activity in nipple aspirates of human breast fluid. Cancer Res. 40: 188-189 (1980)

Philip PA, Rogers HJ, Millis, RR. Acetylator Status and its Relationship to Breast Cancer and Other Deseases of the Breast. Eur. J. Cancer Clinic Oncol. Vol.23. No.11: 1701-1706 (1987).

Philips R, Gafinkel L, Kuzma J. Mortalitity among California Seventh Day Adventists for selected cancer sites. J Natl Cancer Inst. 65: 1097 (1980)

Phillips KA, Glendon G, Knight J. Putting the risk of breast cancer in perspective. N Engl J Med. 340: 141.

[Seite 82↓]

Pike M, Henderson B, Casacrande J. Oral contraceptive use and early abortion as risk factors for breast cancer in young women. Br J Cancer. 43: 720 (1983)

Brind J, Chinchilli V, Severs W, Summy-Long J. Induced abortion as an independent risk factor for breast cancer. A comprehensive review and meta-analysis. J Epidemiol Comm Health. 50: 481 (1996).

Rich-Edwards J, Goldman M, Willolet W, et al. Adolescent body mass index and ovulatory infertility. Am J Obstet Gynecol. 171: 171 (1994).

Rebbeck TR, Levin AM, Eisen A, et al. Breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers. J Natl Cancer Inst. 91: 1475 (1999).

Ries LAG, Kosary CL, Hankey BF, et al., eds. SEER Cancer Statistics Review, 1973-1996. Bethesda, MD; National Cancer Institute, 1999

Risch A, Wallace DMA, Bathers S, and Sim E. Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer. Hum. Mol. Genet. 4: 231-236 (1995).

Roberts-Thomson I C, Ryan P, Khoo K K, Hart W J, McMichael A J, Butler R N. Diet, Acetylator phenotype and risk of colorectal neoplasia. Lancet. 374: 1372-1374 (1996).

Rockhill B, Willet W, Hunter D, et al. A prospective study of recreational physical activity and breast cancer risk. Arch Intern Med. 159: 2290 (1999).

Rohan TE, Baron JA. Cigarette smoking and breast cancer. Am J Epidemiol. 129: 36-42 (1989) .

Romieu I, Berlin J, Colditz G. Oral contraceptives and breast cancer: review and meta-analysis. Cancer. 66: 2253 (1990)

[Seite 83↓]

Roots I, Drakulis N, Ploch M, Heynemeyer G, Loddenkemper R, Minks T, Nitz M, Otte F, Koch M: Debrisoquine hydroxylation phenotype, Acetylation phenotype, and ABO blood groups as genetic host factors of lung cancer risk. Klin. Wochenschr. 66: 87-97 (1988).

Roots I, Drakulis N, Brockmöller J. Polymorphic enzymes and cancer risk: concepts, methodology and data review. In Kalow, W.: Pharmacogenetics of drug metabolism. Pergamon, New York. 815-841 (1992).

Rosenberg L, Palmer J, Kaufman D, et al. Breast cancer in relation to the occurence ad time of the induced and spontaneous abortion. Am J Epidemiol. 127: 981 (1988)

Ross R, Paganini-Hill A, Wan P, Pike M. Effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin. J Natl Cancer Inst. 16: 328 (2000).

Sadrieh N, Davis CD, Synderwine EG. N-Acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland. Cancer Res. 56: 2683-2687 (1996).

Salber EJ, Trichopoulos D, MacMahon B. Lactation and reproductive histories of breast cancer patients in Boston. J Natl Cancer Inst. 43: 1013-1024 (1969)

Salmon R, Ansquer Y, Asselain B, et al. Clinical and biological characteristics of breast cancers in postmenopausal women receiving hormone replacement therapy for meno-pause. Oncol Rep. 65: 699 (1999).

Sambrook J, Fritsch E F, Maniatis T. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New Yorck 2nd ed. 13.1.-13.104 (1989).

Schairer C, Lubin J, Troisi R, et al. Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk. JAMA. 283: 485 (2000).

[Seite 84↓]

Schatzkin A, Carter CL, Green SB, et al. Is alcohol consumption related to breast cancer? results form the Framingham Heart Study. J Natl Cancer Inst. 81: 31-35 (1989)

Schechter MT, Miller AB, Howe GR, Baines CJ, Craib KJ, Wall C. Cigarette smoking and breast cancer: case controll studies of prevalent and incident cancer in the Canadian National Breast Breast Screening Study. Am J Epidemiol. 130: 230-220 (1989)

Schmoll H-J, Höffken K, Possinger K (Hrsg.). Kompendium Internistische Onkologie. Springer, 3. Auflage (1999).

Schöps W, Prior V, Golka K, Blaszkewicz M, Cascorbi I, Roots I, Bolt H M, Kierfeld G. Untersuchung zur klinischen Relevanz der Acetylierephänotypisierung bei 196 Urotheltumorpatienten. Urologe 36: 64-67 (1997).

Shirai T, Fysh FM, Lee M-S, Vaught JB, King CM. Relationship of metabolic activation of N-hydroxy-N-acylarylamines to biological response in the liver and mammary gland of the female CD rat. Cancer Res. 41: 4346-4353 (1981).

Sillero-Arenas M, Delgado-Rodrigez M, Rodigues-Canteras R, et al. Menopausal hormone replacement therapy and breast cancer: a meta-analyses. Obstet Gynecol. 79: 286 (1992)

Steinberg K, Thacker S, Smith S, et al. A meta-analysis of the effect of estrogen replacement therapy on the risk of breast cancer. JAMA. 265: 1985 (1991)

Stockwell H G, Lyman G H. Cigarette smoking and the risk of female reproductive cancers. Am J Obstet Gynecol. 157: 35-40 (1987)

Swaminathan S, Frederickson S M, Hatcher J F. Metabolic activation of N-hydroxy-4-Acetyl-aminobiphenyl by cultured human breast epithelial cell line MCF 10A. Carcino-genesis. 15: 611-617 (1994)

Thomas D. Oral contraceptives and breast cancer: review of the epidemiologic literature. Contraception. 43: 597 (1991)

[Seite 85↓]

Thomas D. Oral contraceptives and breast cancer: review of the epidemiologic literature. Contraception. 43: 597 (1991)

Thune I, Brenn T, Lund E, Gaard M. Physical activity and the risk of breast cancer. N Engl Med. 336: 1269 (1997).

Tokunada M, Land C, Yamamoto T, et al. Incidence of female breast cancer among atomic bomb survivers, Hiroshima and Nagasaki. Radiat. Res. 112: 243 (1987).

Tonelli QJ, Custer RP, Sorof S. Transformation of cultured mouse mammary glands by aromatic amines and amides and their derivates. Cancer Res. 39: 1784-1792 (1979)

Trichopoulos D, MacMahon B, Cole P. Menopause and breast cancer risk. J Natl Cancer Inst. 48: 605 (1972)

Trichopoulos D, Hsieh C, MacMahon B. Age at first birth and breast cancer risk. Int J Cancer. 31: 701 (1983)

Trichopoulos D, Yen S, Brown J. The effect of westernization of urine estrogens, frequency of ovulations, and breast cancer risk. Cancer. 53: 187 (1984)

Vatsis K P, Martell K J, Weber W W. Diverse point mutations in the human gene for polymorphic N-Acetyltransferase. Proc. Natl. Acad. Sci., USA. 88: 6333-6337 (1991)

Vatsis K P, Weber W W, Bell D A, Dupret J M, Evans D A P, Grant D M, Hein D W, Lin H J, Meyer U A, Relling M V, Sim E, Suzuki T, Yamazoe Y. Nomenclature for N-Acetyltransferases. Pharmacogenetics. 5: 1017 (1995).

Vatten L J, Kvinnsland S. Cigarette smoking and risk of breast cancer: a prospective study of 24.329 Norwegian women. Eur J Cancer. 26: 830-833 (1990).

Vessey M, Baron J, Doll R, Mc Pherson K, Yeates D. Oral contraceptives and breast cancer: final report of an epidemiological study. Br J Cancer. 47: 455-462 (1983)

[Seite 86↓]

Webster D J T, Flook D, Jenkins J, Hutchings A, Routledge PA. Drug acetylation in breast cancer. Br. J. Cancer. 60: 236-237 (1989).

Willet W, Stampfer M, Golditz G. Dietary fat and risk of breast cancer. N Engl J Med. 16: 22 (1987)

Wang C Y, Yamada H, Morton K C, Zukowsky K, Lee M-S, King C M. Induction of repair synthesis of DNA in mammary and urinary bladder epithelial cells by N-hydroxy derivatives of carcinogenic arylamines. Cancer Res. 48: 4227-4232 (1988).

Wingo P, Lee N, Ory H, et al. Age specific differences in the relationship between oral contraceptive use and breast cancer. Obstet Gynecol. 78: 161 (1991)

Yuan J, Yu M, Ross R, et al. Risk factors for breast cancer in Chinese women in Shanghai. Cancer Res. 48: 1949 (1988)

Ziegler R, Hoover R, Nomura A, et al.. Relative Weight, weight change, height, and breast cancer risk in Asian-American women. J Natl Cancer Inst. 88: 650 (1996).

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