[page x↓]

List of Abbreviations

A (mA)

ampère (milliampère)

ADP

Adenosine diphosphate

ATP

Adenosine triphosphate

bp

base pair

BSA

bovine serum albumin

°C

degree Celsius

CHAPS

3-[(3-cholamidopropyl)-dimethylammonio]-propan-sulfonate

cm

centimeter

CoA

coenzyme A

Complex I

NADH:ubiquinone oxidoreductase

Complex III

ubiquinol:cytochrome c oxidoreductase

Complex IV

cytochrome c oxidase

Complex V (F0F1ATPase)

adenosine triphosphate synthase

CPEO

chronic progressive external ophthalmoplegia

1D

first dimension

2D

second dimension

Da (kDa)

dalton (kilodalton)

DIDMOAD

diabetes insipidus, diabetes mellitus, optic atrophy and deafness

DMSO

dimethylsulfoxide

DNA

desoxyribonucleic acid

DTT

1,4-dithiothreitol

EBV

Epstein-Barr-virus

EDTA

ethylenediaminetetraacetic acid

EMBL

European Molecular Biology Laboratory

FADH2

reduced flavin adenine dinucleotide

g (mg, ng)

gram (milligram, nanogram)

g

gravity (used in centrifugation)

h

hour

IEF

isoelectric focussing

kbp

kilobase pairs

l (ml, µl)

liter (milliliter, microliter)

LHON

Leber’s hereditary optic neuropathy

M (mM)

molar (millimolar)

MALDI-TOF

matrix assisted laser desorption/ionisation – time of flight

MALDI-QTOF

matrix assisted laser desorption/ionisation –quadrupole/time of flight

MELAS

mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes

MERRF

myoclonicus epilepsy with ragged-red fibres

min

minute

MOPS

3-morpholinopropanesulfonic acid

MW

molecular weight

mtDNA

mitochondrial DNA

NADH

reduced nicotinamide adenine dinucleotide

No.

number

PDH

pyruvate dehydrogenase

PDHc

pyruvate dehydrogenase complex

pI

isoelectric point

Q1

selection cell (in MALDI-QTOF-MS)

Q2

collision cell (in MALDI-QTOF-MS)

RNA

ribonucleic acid

rpm

rotations per minute

rRNA

ribosomale RNA

SDH

succinate: ubiquinone oxidoreductase

SDS

sodium dodecylsulfate

SDS-PAGE

sodium dodecylsulfate-polyacrylamide gel electrophoresis

sec

second

TEMED

N,N,N’,N’-tetramethylethylenediamine

TFA

trifluoroacetic acid

TIM

translocases of the inner membrane

TOM

translocases of the outer membrane

TOF

time-of-flight

Tris-base

tris(hydroxylmethyl)-amoniomethane

Tris-HCl

trizma hydrochloride

tRNA

transfer RNA

v/v

volume per volume

V (mV)

volt (millivolt)

w/v

weight per volume


[page xiii↓]

List of INTERNET sites

Internet site name

Internet address

Blast 2 sequences

http://www.ncbi.nlm.nih.gov/blast/bl2seq/bl2.html

GenBank

http://www.ncbi.nlm.nih.gov/

Genome Database (GDB)

http://gdbwww.gdb.org/

Human Mitochondrial Genome Database (mtDB)

http://www.genpat.uu.se/mtDB/

Human Mitochondrial Proteins Database

http://bioinfo.nist.gov:8080/examples/servlets/Descrition.html

LocusLink

http://www.ncbi.nlm.nih.gov/LocusLink/

MASCOT

http://matrixscience.com

Mendelian Inheritance and the
MITOCHONDRION (MitoDat)

http://srdata.nist.gov/mitdb/

MITOMAP

http://www.mitomap.org/

MITOP

http://mips.gsf.de/cgi-bin/proj/medgen/filter_cat.pl?h+fun

MS-Fit

http://Prospector.ucsf.edu

NCBI

http://www.ncbi.nlm.nih.gov/

Neuromuscular Disease Center

http://www.neuro.wustl.edu/neuromuscular/mitosyn.html

Online Mendelian Inheritance in Man (OMIM)

http://www.ncbi.nlm.nih.gov/omim/

PepSea

http://195.41.108.38/PepSeaIntro.html

PeptideMass

http://www.expasy.ch/tools/peptide-mass.html

PeptIdent

http://www.expasy.ch/tools/peptident.html

PeptideSearch

http://www.mann.embl-heidelberg.de/GroupPages/PageLink/peptidesearchpage.html

ProFound

http://129.85.19.192/profound_bin/WebProFound.exe

Protein Data Bank (PDB)

http://nist.rcsb.org/pdb/

SOSUI

http://sosui.proteome.bio.tuat.ac.jp/sosuiframe0.html

Swiss-Prot/ TrEMBL

http://www.expasy.ch/cgi-bin/sprot-search-ful


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