S. 873-876
peer_reviewed
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| edoc-Server der Humboldt-Universität zu Berlin |
| Publikationsart: | Artikel |
| Autor(en): | Michael Vogeser; Karl Jacob |
| Titel: | Measurement of Free Triiodothyronine in Intensive Care Patients – Comparison of Two Routine Methods |
| Erschienen in: |
Clinical Chemistry and Laboratory Medicine 35 (11)
2009 S. 873-876 |
| Verlag: |
de Gruyter |
| ISSN: | 1434-6621, 1437-4331 |
| DOI: | 10.1515/cclm.1997.35.11.873 |
| Erstveröffentlichung: | 1997 |
| Veröffentlichung auf edoc: | 01.07.2010 |
| Status: |
published peer_reviewed |
| Volltext: | pdf (urn:nbn:de:kobv:11-100170468) |
| Fachgebiet(e): | Chemie |
| Einrichtung: | Kooperation de Gruyter |
| Metadatenexport:
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|
Endnote Bibtex |
| Abstract (eng): |
| One hundred sera from intensive care patients, and 93 sera from endocrinological outpatients were used for a comparison between two automated assays for free triiodothyronine (Enzymun Test, and Elecsys 2010, both Boehringer Mannheim, Mannheim, Germany). In outpatients a good correlation between both methods was found (r=0.932). In contrast, comparability between the two assays was poor in intensive care patients (r=0.75, after exclusion of two outliers); significantly more values in the hypothyroid range were found with the Elecsys 2010 assay (n=83, compared with n=33 with the Enzymun Test; x2 test p=0.001). We conclude that routine measurement of free triiodothyronine which has the theoretical advantage of quantifying the biologically active fraction of thyroid hormones may have methodological limitations in severely ill patients. |
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