Blohmer, Dr. Jens-Uwe: Kontrastmittel-Videodensitometrie und Automatisierte Mikroskop-Bildanalyse zur Messung der Durchblutung und Vaskularisation von Mammakarzinomen

73-80

Literaturverzeichnis

1 Goldman E: "The growth of malignant desease in man and the lower animals with special reference to the vascular system. . " Lancet. Band ii. 1907, S.1236-1240,

2 Folkman J: "What is the evidence that tumors are angiogenesis dependent?. " J Natl Cancer Inst. Band 82. 1990, S.4-6,

3 Pluda JM: "Tumor-associated angiogenesis - mechanism, clinical implications, and therapeutic strategies. " Semin Oncol. 1997, 24, S.203-218,

4 Folkman J: ". Angiogenesis inhibitors generated by tumors. " Mol Med. 1995, 1, S.120-122,

5 Holmgren L, O‘Reilly MS, Folkman J: "Dormancy of micrometastases - balanced proliferation and apoptosis in the presence of angiogenesis suppression. " Nat Med. 1995, 1, S.149-153,

6a Feldmann HJ, Sievers K, Füller J, Molls M, Löhr E: "Evaluation of tumor blood perfusion by dynamic MRI and CT in patients undergoing thermoradiotherapy. " Eur J Radiol. 1993, 16, S.224-229,

6b Mazure NM, Chen EY, Laderoute KR, Giaccia AJ: "Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial-growth factor expression. . " Cancer Res. 1996, 56, S.3436-3440,

7 Gasparini G, Weidner N, Bevilacqua P, Maluta S, Dalla Palma P, Caffo O, Barbareschi M, Marubini E, Pozza F: "Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma. . " J Clin Oncol. 1994, 12, S.454-466,

8 Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW, Giaccia AJ: "Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors. . " Nature. 1996, 379, S.88-91,

9 Claffey KP, Robinson GS: "Regulation of vegf/vpf expression in tumor cells - consequences for tumor-growth and metastasis. . " Cancer Metastasis Rev. 1997, 15, S.165-176,

10 Folkman J, Klagsbrun M, Sasse J, Wadzinski M, Ingber DE, Vlodavsky I: "A heparin-binding angiogenic protein -- basic fibroblast growth factor -- is stored within basement membrane. " Am J Pathol. 1988, 130, S.393-400,

11 Polverini PJ, Leibovich JS: "Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages. . " Lab Invest. 1984, 51, S.635-642,

12 Dameron KM, Volpert OV, Tainsky MA, Bouck N: "Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. " Science. 1994, 265, S.1582-1584,

13 Bunn HF, Poyton RO: "Oxygen sensing and molecular adaptation to hypoxia. " Physiol Rev. 1996, 76, S.839-885,

14 Senger DR, Water L van de, Brown LF, Nagy JA, Yeo KT, Yeo TK, Berse B, Jackman RW, Dvorak AM, Dvorak HF: "Vascular permeability factor (VPF, VEGF) in tumor biology. " Cancer and Met Rev. 1993, 12, S.303-324,

15 Konerding MA, Ackern C van, Fait E, Steinberg F, Streffer C: "Morphologic aspects of tumor angiogenesis and microcirculation. In: Molls M, Vaupel P (eds) Blood perfusion and microenvironment of human tumors. " Hrsg.: Molls M, Vaupel P: Blodd perfusion and microenvironment of human tumors1. 1 Berlin, Springer, 1998 S.5-17,

16 Endrich B, Vaupel P: "The role of the microcirculation in the treatment of malignant tumors: facts and fiction. . " Hrsg.: Molls M, Vaupel P: Blood perfusion and microenvironment of human tumors. 1 Berlin, Springer, 1998 S.19-39,

17 Boucher Y, Jain RK: "Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse. " Cancer Res. 1992, 52, S.5110-5114,

18 Jain RK: "Haemoynamic and transport barriers to the treatment of solid tumors. " Int J Radiat Biol. 1991, 60, S.85-100,

19 Schweigerer L, Neufeld G, Friedman J, Abraham JA, Fiddes JC, Gospodarowicz D: "Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth. " Nature. 1987, 325, S.257-262,

20 Motro B, Itin A, Sachs L, Keshet E: "Pattern of interleukin 6 gene expression in vivo suggests a role for this cytokine in angiogenesis. " Proc Natl Acad Sci USA. 1990, 87, S.3092,

21 Podor TJ, Jirik FR, Loskutoff DJ, Carson DA, Lotz M: "Human endothelial cells produce IL-6. Lack of responses to exogenous IL-6. " Ann NY Acad Sci. 1989, 557, S.374-385,

22 Folkman J: "Angiogenic therapy. " Hrsg.: DeVita VT, Hellman S, Rosenberg SA: Cancer: Principles & Practice of Oncology. Philadelphia, Lipincott-Raven, 1997 S.3075-3085,

23 Harris AL: "Hypoxia, a key regulator of tumor growth and target for therapy. . " Breast Cancer Res Treat. 1998, 50 Special issue, S.226,

24 Drevs J, Droll A, Mross K, Unger C: "Angiogenesis inhibition: Drugs in clinical trials. . " Onkologie. 1999, 22, S.282-290,

25 Vaupel P: "Tumor blood flow. " Hrsg.: Molls M, Vaupel P: Blood perfusion and microenvironment of human tumors. 1 Berlin, Springer, 1998 S.40-45,

26 Hill SA, Pigott KH, Saunders ML: "Microregional blood flow in murine and human tumours assessed using laser Doppler microprobes. " Br J Cancer. 1996, 74, S.260-263,

27 Jirtle RL: "Chemical modification of tumor blood flow. " Int J Hyperthermia. 1988, 4, S.355-371,

28 Feldmann HJ, Sievers K, Füller J, Molls M, Löhr E: "Evaluation of tumor blood perfusion by dynamic MRI and CT in patients undergoing thermoradiotherapy. " Eur J Radiol. 1993, 16, S.224-229,

29 Laubenbacher C, Schwaiger M: "The potential role of Positron Emission Tomography in Investigation of Microenvironment. " Hrsg.: Molls M, Vaupel P: Blood perfusion and microenvironment of human tumors. 1 Berlin, Springer, 1998 S.161-191,

30 Sohn C, Grischke EM, Wallwiener E, Kaufmann M, Fournier D von, Bastert G: "Die sonographische Durchblutungsdiagnostik gut- und bösartiger Tumoren. " Geburtshilfe Frauenheilkd. 1992, 52, S.397-403,

31 Sohn C, Wskott HP, Schießer M: "Sensitivität neuer Farbsysteme: Maximum Entropy Method und Angio-Farbe. " Ultraschall in Med. 1996, 17, S.138-142,

32 Schlief R, Bauer A: "Ultraschallkontrastmittel - Neue Perspektiven in der Ultraschalldiagnostik. " Radiologe. 1996, 36, S.51-57,

33 Cohen F, Kuwatsuru R, Shames D: "Contrast-enhanced MRI estimation of altered capillary permeability in experimental mammary carcinomas following x-irradiation. " Invest Radiol. 1995, 162, S.205-210,

34 Sherif H, Mahfouz AE, Oelllinger H, Hadijuana J, Blohmer JU, Taupitz M, Felix R, Hamm B: "Peripheral Washout Sign on Contrast-enhanced MR Images of the Breast. " Radiology. 1997, 205, S.209-213,

35 Cyrlak D: "Induced costs of low-cost screening mammography. " Radiology. 1988, 168, S.661-662,

36 Rimer BK, Schildkraut J: "Cancer screening. " Hrsg.: DeVita VT, Hellman S, Rosenber SA: Cancer: Principles and Practice of Oncology. Philadelphia, Lipincott-Raven, 1997 S.619-631,

37 Schreer I, Eidtmann H: "Früherkennung und Prognosefaktoren beim Mammakarzinom. " Onkologe. 1998, 4, S.902-913,

38 Blohmer JU, Hüttner C, Lichtenegger W: "Qualitätssicherung des operativen Vorgehens bei nicht tastbaren Mammaläsionen. " Geburtshilfe Frauenheilkd. 1999, 59, S.M21-M24,

39 Blohmer JU, Oellinger H, Schmidt C, Hufnagl P, Felix R, Lichtenegger W: "Comparison of Various Imaging Methods with Particular Evaluation of Color-Doppler Sonography for Planning Surgery for Breast Tumors. " Archives of Gynecology and Obstetrics. 1999, 262, S.159-171,

40 Marquet KL, Funk A, Fendel H, Handt S: "Der echodichte Randsaum und hyperreflexive Ausläufer: Sensible Kriterien maligner Prozesse in der Mammasonographie. " Geburtshilfe Frauenheilkd. 1993, 53, S.20-23,

41 Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA: " Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. " Radiology. 1995, 196, S.123-134,

42 Teubner J, Bohrer M, Kaick G van, Georgi M: "Echomorphologie des Mammakarzinoms. " Radiologe. 1993, 33, S.277-286,

43 Blohmer JU, Bollmann R, Heinrich G, Paepke S, Lichtenegger W: "Die dreidimensionale Ultraschalluntersuchung (3D-Sonographie) der weiblichen Brustdrüse. " Geburtshilfe Frauenheilkd. 1996, 56, S.161-165,

44 Blohmer JU, Oellinger H, Heinrich G, Grineisen Y, Paepke S, Bollmann R, Lichtenegger W: "3D-Ultraschall der weiblichen Brustdrüse. " Hrsg.: Schmidt W: Jahrbuch der Gynäkologie und Geburtshilfe. Band 1997/1998. Zülpich, Biermann, 1998 S.199-205,

45 Blohmer JU, Guski H: "Sonographische Kriterien zur Differentialdiagnose von Mammatumoren. " Hrsg.: Sohn C, Holzgreve W: Ultraschall in Gynäkologie und Geburtshilfe. 1 Stuttgart, Thieme, 1995 S.671-718,

46 Blohmer JU, Schmalisch G, Kürten A, Chaoui R, Lichtenegger W: "Relevance of sonographic criteria to differential diagnosis of mammary tumour. " Eur J Ultrasound. 1997, 6, S.35-41,

47 Bader W, Böhmer S, Otto WR, Degenhardt F, Schneider J: "Texturanalyse: Ein neues Verfahren zur Beurteilung sonographisch darstellbarer Herdbefunde der MammaEin neues Verfahren zur Beurteilung sonographisch darstellbarer Herdbefunde der Mamma. " Bildgebung. 1994, 61, S.284-290,

48 Dudwiesus P: "Physikalische Grundlagen. " Hrsg.: Sohn C, Holzgreve W: Ultraschall in Gynäkologie und Geburtshilfe. 1 Stuttgart, Thieme, 1995 S.7-62,

49 Huber S, Delorme S, Zuna I: "Dynamische Erfassung der Kontrasmittelanflutung in der Dopplersonographie. Gegenwärtiger Stand. " Radiologe. 1998, 38, S.390-393,

50 Huber S, Helbich T, Kettenbach J, Dock W, Zuna I, Delorme S: "Effects of microbubble contrast agent on breast tumors: computer-assisted quantitative assessment with color Doppler US - early experience. " Radiology. 1998, 208, S.485-489,

51 Goldhirsch A, Glick JH, Gelber RD, Senn HJ: "International consensus panel on the treatment of primary breast cancer V: Update 1998. " Hrsg.: Senn HJ, Gelber RD, Goldhirsch A, Thürlimann B: Recent Results in Cancer Research. 152. Adjuvant Therapy of Primary Breast Cancer VI. Berlin, Springer, 1998 S.481-487,

52 Thomssen C, Jänicke F, Harbeck N, Pache L, Prechtl A, Schmitt M, Graeff H: "Tumorproteasen im multivariaten prognostischen Vergleich und als Hilfe zur risikoadaptierten Therapieentscheidung. " Excerpta Oncologica. 1997, 6, S.135-158,

53 Schönborn I, Minguillon C, Lichtenegger W, Zschiesche W, Spitzer E: "c-erbB-2, EGF-Rezeptor, p53 und PCNA. Die prognostische Bedeutung neuer Faktoren für das Lymphknoten-negative Mammakarzinom. " Geburtshilfe Frauenheilkd. 1995, 55, S.566-571,

54 Harbeck N, Henselmann B, Thomssen C, Pache L, Ulm K, Dettmar P, Nathrath W, Jänicke F, Schmitt M, Graeff H: "Multivariater Vergleich neuerer tumorbiologischer Prognosefaktoren (unter Einschluß von S-Phase und MIB1) beim nodalnegativen Mammakarzinom. " Excerpta Oncologica. 1997, 6, S.91-100,

55 Bosari S, Lee AKC, DeLessis RA, Wiley BD, Heatley GJ, Silverman ML: "Microvessel quantitation and prognosis in invasive breast carcinoma. " Hum Pathol. 1992, 23, S.755-761,

56 Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred EN, Moore DH, Meli S, Gasparini G: "Tumor angiogenesis: A new signifikant and independent prognostic indicator in early-stage breast carcinoma. " J NCI. 1992, 84, S.1875-1887,

57 Weidner N, Semple JP, Welch WR, Folkman J: "Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. " N Eng J Med. 1991, 324, S.1-7,

58 Arapandoni Dadioti-P, Giatromanolaki A, Trihia H, Harris AL. Koukourakis-MI: "Angiogenesis in ductal breast carcinoma. Comparison of microvessel density between primary tumour and lymph node metastasis. " Cancer Lett. 1999, 137, S.145-150,

59 Makris A, Powles TJ, Kakolyris S, Dowsett M, Ashley SE. Harris AL: "Reduction in angiogenesis after neoadjuvant chemoendocrine therapy in patients with operable breast carcinoma. " Cancer. 1999, 85, S.1996-2000,

60 Lee WJ, Chu JS, Huang CS, Chang MF, Chang KJ, Chen KM: " Breast cancer vascularity: Color Doppler sonography and histopathology study. " Breast Cancer Res Treat. 1996, 37, S.291-298,

61 Sohn C, Thiel C, Baudendiestel A, Kaufmann M, Bastert G: "Is the sonographic degree of blood supply a new prognostic factor?. " Breast. 1996, 5, S.110-112,

62 Sterns EE, SenGupta S, Saunders F, Zee B: "Vascularity demonstrated by Doppler ultrasound and immunohistochemistry in invasive ductal carcinoma of the breast. " Breast Cancer Res Treat . 1996, 40, S.197-203,

63 Peters-Engl C, Frank W, Medl M: "Tumor flow in malignant breast tumors measured by Doppler ultrasound: An independent predictor of survival. " Breast Cancer Res Treat. 1998, 50 Special issue, S.228,

64 Modzelewski RA, Davies P, Watkins SC, Auerbach R, Chang MJ, Johnson CS: "Isolation and identification of fresh tumor-derived endothelial cells from a murine RIF-1 fibrosarcoma. " Cancer Res . 1994, 54, S.336,

65 Oktaba AMC, Hunter WL, Aresenault AL: "Taxol: A potent inhibitor of normal and tumor-induced angiogenesis. (Abstract 2707) . " Proc Am Assoc Cancer Res . 1995, 36, S.454,

66 Belotti D, Nicoletti I, Vergani V, Rieppi M, Drudis T, Viale G, Giavazzi R, Taraboletti G: "Paclitaxel (Taxol), a microtubule affecting drug, inhibits tumor induced angiogenesis. (Abstract 397). " Proc Am Assoc Cancer Res. 1996, 37, S.57,

67 Harris AL : "Anti-angiogenesis therapy and strategies for integrating it with adjuvant therapy. . " Hrsg.: Senn HJ, Gelber RD, Goldhirsch A, Thürlimann B: Adjuvant Therapy of Primary Breast Cancer. Berlin, Springer, 1998 S.341-352,

68 Hortobagyi GN, Singletary SE, McNeese MB: "Treatment of locally advanced and inflammatory breast cancer. " Hrsg.: Harris JL: Diseases of the breast. Philadelphia, Lippincott-Raven, 1996 S.585-599,

69 Blohmer JU, Paepke S, Grineisen Y, Lichtenegger W: "Dose-intensified, neoadjuvant chemotherapy with the combination of Epirubicin/Ifosfamid or Docetaxel/Epirubicin in patients with IIIA/IIIB breast cancer: results of a phase II study. . " Proc Am Soc Clin Oncol . 1998, 17, S.129a,

70 Blohmer JU, Paepke S, Kissner L, Elling D, Fleige B, Grineisen Y, Lichtenegger W: "Dose-intensified, preoperative and adjuvant chemotherapy in patients with T3- and T4d-breast cancer: toxicity, clinical and pathological remission. " Zentralbl Gynäkol. 1999, 121, S.522-526,

71 Hortobagyi GN, Buzdar AU: "Locally advanced breast cancer: a review including the M.D. Anderson experience. " Hrsg.: Ragaz J, Ariel IM: High-risk breast cancer. Berlin, Springer, 1991 S.382,

72 Fisher B, Brown A, Mamounas E, Wieand S, Robidoux A, Margolese RG, Cruz AB Jr, Fisher ER, Wickerham DL, Wolmark N, DeCillis A, Hoehn JL, Lees AW, Dimitrov NV: "Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18. " J Clin Oncol. 1997, 15, S.2483-2493,

73 Minckwitz G von, Costa S, Eiermann W, Blohmer JU, Tulusan AH, Jackisch C, Kaufmann M: "Maximized reduction of primary breast tumor size using preoperative chemotherapy with Adriamycin and Docetaxel. " J Clin Oncol. 1999, 17, S.1-7,

74 Junkermann H, Fournier D von: "Bildgebende Verfahren zur Beurteilung des Ansprechens des Mammakarzinoms auf eine präoperative Chemotherapie. " Radiologe. 1997, 37, S.726-732,

75 Kurtz B, Achten Ch, Audretsch W, Rezai M, Urban P, ZochollG: "MR mammographische Beurteilung desTumoransprechverhaltens nach neoadjuvanter Radiochemotherapie lokal fortgeschrittener Mammakarzinome. " Fortschr Röntgenst. 1996, 164, S.469-474,

76 Kalra R, Wade KE, Hands L, Styles P, Camplejohn R, Greenall M, Adams GE, Harris, AL,Radda GK: "Phosphomonoester is associated with proliferation in human breast cancer: a 31 P MRS study. " Br J Cancer. 1993, 67, S.1145-1153,

77 Knopp MV, Heß T, Bachert P, Ende G, Junkermann H, Hesterkamp T, Kaick G.van: "Magnetresonanzspektroskopie des Mammakarzinoms. " Radiologe. 1993, 33, S.300-307,

78 Byrne GJ, Blann AD, Venizelos V, Iddon A, Howell A, Bundred NJ: "Serum soluble VCAM: A surrogate marker of angiogenesis. " Breast Cancer Res Treatm. 1998, 50 Special issue, S.330,

79 Sohn C, Blohmer JU: "Durchblutungsdiagnostik von Mammatumoren. " Hrsg.: Sohn C, Blohmer JU: Mammasonographie. Ein systematisches Lehrbuch zur Technik und Befundinterpretation. 1 Stuttgart, Thieme, 1996 S.130-138,

80 Sittek H, Keßler M, Reiser M, Hepp M: "Mammographiescreening und qualitätsgesicherte Früherkennung in Deutschland. " Hrsg.: Untch M, Konecny G, Sittek H, Keßler M, Reiser M, Hepp H: Diagnostik und Therapie des Mammakarzinoms. 1 München, Zuckschwerdt, 19981 S.193-219,

81 Bloom HJG, Richardson WW: "Histological grading and prognosis in breast cancer. A study of 1409 cases of which 359 have been followed for 15 years. " Br J Cancer. 1957, 11, S.359-377,

82 Sinn HP, Schmid H, Junkermann H, Huober J, Leppien G, Kaufmann M, Bastert G, Otto HF: "Histologische Regression des Mammakarzinoms nach primärer (neoadjuvanter) Chemotherapie. " Geburtshilfe Frauenheilkd. 1995, 54, S.552-558,

83 Blohmer JU, Paepke S, Fleige U, Grineisen Y, Kissner L, Ernhardt B, Elling D, Kohls A, Lichtenegger W: "ADose-Intensified, Sequential Preoperative Chemotherapy with Epirubicin and Docetaxel in Patients with Inoperable and Non Metastastic Breast Cancer: A Prospective, Controlled, Multicentre Phase II Study. " Proc Am S Clin Oncol. 1999, 18, S.89a,

84 Dock W: "Duplex sonography of mammary tumors: a prospective study of 75 patients. " J Ultrasound Med. 1993, 12, S.79-82,

85 Blohmer JU, Bollmann R, Schmalisch A, Chaoui R, Lau HU: "Die Differentialdiagnose von Mammatumoren durch den Vergleich der Durchblututng des Tumors mit der kontralateralen Brust mittels farbkodierter, gepulster Dopplersonographie. " Geburtshilfe Frauenheilkd. 1995, 55, S.1-6,

86 Leek RD, Landers RJ, Harris AL, Lewis CE: "Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. " Br J Cancer. 1999, 79, S.991-995,

87 Sahin-Akyar G, Sumer H: "Color Doppler ultrasound and spectral analysis of tumor vessels in the differential diagnosis of solid breast masses. " Invest Radiol. 1996, 31, S.72-79,

88 Youssefzadeh S, Eibenberger K, Helbich T, Jakesz R, Wolf G: "Use of resistance index for the diagnosis of breast tumours. " Clin Radiol. 1996, 51, S.418-420,

89 Jain RK: "Determinants of tumor blood flow: a review. " Cancer Res. 1988, 48, S.2641-2658,

90 Kedar RP, Cosgrove DO, Smith IE, Mansi JL, Bamber JC: "Breast carcinoma: Measurement of tumor response to primary medical therapy with color Doppler flow imaging. " Radiology. 1994, 190, S.825-830,

91 Mäurer J, William C, Schroeder R, Hidajad N, Hell B, Bier J, Weber S, Felix R: "Evaluation of metastases and reactive lymph nodes in Doppler sonography using an ultrasound contrast enhancer. " Invest Radiol. 1997, 32, S.441-446,

92 Kurjak A, Salihagic A, Kupesic-Urek S: "Clinical value of assessment of gynaecological tumour angiogenesis by transvaginal colour Doppler. " Ann Med. 1992, 24, S.97-102,

93 Madjar H, Vetter M, Prömpeler H, Breckwoldt M, Pfleiderer A: "Doppler measurement of breast vascularity in women under pharmacologic treatment of benign breast disease. " J Reprod Med. 1993, 38, S.935-940,

94 Madjar H, Prömpele H, Wolfahrt R, Bauknecht T, Pfleiderer, A: "Farbdopplerflußdaten von Mammatumoren. " Ultraschall Med. 1994, 15, S.69-76,

95 Schelling M, Gnirs J, Braun M, Busch R, Maurer S, Kuhn W, Schneider KTM, Graeff H: "Optimized differential diagnosis of breast lesions by combined B-mode and color Doppler sonography. " Ultrasound Obstet Gynecol. 1997, 10, S.48-53,

96 Delorme S, Zuna I, Huber S, Albert B, Lohr F, Knopp V, Junkermann H, Kaik G van: "Farb-Dopplersonographie bei Mammatumoren: Quantifizierung durch computergestützte Verfahren. " Tumordiagn u Ther. 1995, 16, S.180-186,

97 Cosgrove D, Eckersley R: "Doppler indices in tumors--resolution of a dilemma?. " Ultrasound Obstet Gynecol. 1997, 10, S.9-11,

98 Stuhrmann M, Aronius R, Roefke C, Schietzel M: "Vaskularisation von Mammatumoren: Einsatz des Ultraschallkontrastmittels in der Dignitätsbeurteilung. Vorläufige Ergebnisse. " RöFo. 1998, 169, S.360-364,

99 Fleischer AC, Jones III HW: Early detection of ovarian carcinoma with transvaginal sonography. 1 New York, Raven Press, 1993

100 Shubik P: "Vascularization of tumors: a review. " J Cancer Res Clin Oncol. 1982, 103, S.211-226,

101 Bamber JC, Eckersley, RJ, Bush NL, Bell DS, Crawford DC: "Data processing for 3-dimensional visualization of tumor anantomy and blood flow. " Hrsg.: Bellingham W: Visualization in biomedical computing. London, SPIE, 1992 S.651-663,

102 Kedar RP, Cosgrove DO, Bamber JC, Bell DS: "Automated quantification of color Doppler signals: a preliminary study in breast tumors. " Radiology. 1995, 197, S.39-43,

103 Oellinger H, Siewert C, Sherif HK, Blohmer JU, Hadijuana J, Lichtenegger W, Felix R: "Is there a a method to distinguish a fibroadenoma from a carcinoma in MR-female-breast-imaging (MRFBI)? . " Magnetic Resonance Materials in Physics, Biology, and Medicine. 1996, 4 Suppl, S.204,

104 Fischer U, V. Heyden D, Vosshenrich R, Vieweg I, Grabbe E: "Signalverhalten maligner und benigner Läsionen in der dynamischer 2-D-MRT der Mamma. " Fortschr Roentgenstr. 1993, 15814, S.287-297,

105 Greenstein O: "Staging of suspected breast cancer: Effect of MR imaging and MR-guided biopsy. " Radiology. 1995, 196, S.115-122,

106 Fisher B: "The effect of recent findings from NASBP clinical trials on pradigms governing the therapy of primary invasive breast cancer. " Hrsg.: Untch M, Konecny H, Sittek H, Keßler M, Reiser M, Hepp H: Diagnostik und Therapie des Mammakarzinoms. München, Zuckschwerdt, 1998 S.193-219,

107 Less JR, Skalak TC, Sevick EM, Jain RK: "Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions. " Cancer Res. 1991, 51, S.265-273,

108 Grüner C, Schönwälder A, Schulz-Wendland R, Lang N, Bautz W: "Welche Rolle spielt die Farbdopplersonographie, unterstützt mit dem Echosignalverstärker Levovist?, in der komplementären Mammadiagnostik?. " Akt Radiol. 1998, 8, S.58-62,

109 Rubin JM, Bude RO, Carson PL, Bree RL, Adler RS: "Power Doppler US: a potentially useful alternative to mean frequency-based color Doppler US. " Radiology. 1994, 190, S.853-856,

110 Cosgrove D: "Why do we need contrast agents for ultrasound. " Clinical Radiology. 1996, 51 Suppl 1, S.1-4,

111 Blomley M: "Functional imaging with microbubble agents. " Europ J Ultrasound. 1997, EURODOP97, S.C6.5,

112 Albrecht T, Patel N, Cosgrove DO, Jayaram V, Blomley MJ, Eckersley R: "Enhancement of power Doppler signals from breast lesions with the ultrasound contrast agent EchoGen emulsion: subjective and quantitative assessment. " Acad Radiol. 1998, 5 Suppl 1, S.S195-S199,

113 Blohmer JU, Oellinger H, Grineisen Y, Paepke S, Siewert C, Siebert G, Felix R, Lichtenegger W: "Changes in Spectral Doppler Measurement of Vmax after Administration of an Ultrasound Contrast Agent - A Possible New Variable for the Differential Diagnosis of Breast Lesions. " TumorDiagn u Ther. 1999, 20, S.1-7,

114 Lück HJ, Thomssen C, du Bois A, Lisboa BW, Untch M, Kühnle H, Jänicke F, Meerpohl HG, Lindner C, Konecny G, Hecker D, Diergarten K: "Preliminary results of a phase II study of epirubicin and paclitaxel as first-line treatment in patients with metastatic breast cancer. " Semin Oncol. 1997, 24 Suppl 3, S.S13-S16,

115 Segel MC, Paulus D, Hortobagyi GN: "Segel MC, Paulus D, Hortobagyi GN. " Radiology. 1988, 169, S.49-54,

116 Knopp MV, Brix G, Junkermann HJ, Sinn HP: "MR mammography with pharmacocinetic mapping for monitoring of breast cancer treatment during neoadjuvant therapy. " MRI Clin N Am. 1994, 2, S.633-652,

117 Rieber A, Zeitler H, Rosenthal H, Görich J, Kreienberg R, Brambs HJ, Tomczak R: "MRI of breast cancer: influence of chemotherapy on sensitivity. " British J Radiology. 1997, 70, S.452-458,

118 Moon RB, Richards JH: "Determination of intracellular pH by 31 P-magnetic resonance. " J Biol Chem. 1973, 248, S.7276-7278,

119 Thian CNG, Grundfest S, Vijayakumar S, Baldwin NJ, Mayors AW, Karalis I, Meaney TF, Shin KH, Thomas FJ, Tubbs R: "Therapeutic response of breast carcinoma monitored by 31P MRS in si. " Magnetic Resonance in Medicine . 1989, 10, S.125-134,

120 Smith IC: "Smith IC. " Eur J Surg Oncol. 1998, 24, S.320-329,

121 Blohmer JU, Gohlke A, Hufnagl P, Schneider U, Lichtenegger W: "Correlation between morphologic parameters of vascularisation, color Doppler image features (CD) and lymph-node metastasis in breast cancer. " Breast Cancer Res Treatm . 1998, 50, S.331,

122 Axelsson K, Ljung BE, Moore DH 2nd, Thor AD, Chew KL, Edgerton SM, Smith HS, Mayall BH: "Tumor angiogenesis as a prognostic assay for invasive ductal breast carcinoma. " J Natl Cancer Inst. 1995, 87, S.997-1008,

123 Horak ER, Leek R, Klenk N, LeJeune S, Smith K, Stuart N, Greenall M, Stepniewska K, Harris A: "Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer. " Lancet. 340, 1120-1124,

124 Fox SB, Leek RD, Weekes MP, Withehouse RM, Gatter KC, Harris AL: "Quantification and prognostic value of breast cancer angiogenesis: Comparison of micorvessel density, Chalkley count, and computer image analysis. " J Pathology. 1995, 177, S.275-283,

125 Grischke EM, Kaufmann M, Eberlein-Gonska M, Mattfeldt T, Sohn Ch, Bastert G: "Angiogenesis as a diagnostic factor in primary breast cancer: microvessel quantitation by stereological methods and correlation with color Doppler sonography. " Onkologie. 1994, 17, S.35-42,

126 Parums DV, Cordell JL, Micklem K, Heryet AR, Gatter KC, Mason DY: "JC70: A new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. " J Clin Pathol. 1990, 43, S.752-757,

127 Toi M, Inada K, Suzuki H, Tominaga T: "Tumor angiogenesis in breast cancer: ist importance as a prognostic indicator and the association with vascular endothelial growth factor expression. " Breast Cancer Res Treatm. 1995, 36, S.193-204,

128 Hall N, Fish D, Hunt N, Goldin R, Guillou P, Monson J: "Hall N, Fish D, Hunt N, Goldin R, Guillou P, Monson J. " Surg Oncol. 1992, 1, S.223-229,

129 Ellis LM, Fidler IJ: Angiogenesis and breast cancer metastasis. Stuttgart, Thieme, 1995 S.388-390,

130 Blohmer JU, Oellinger H, Schmidt C, Lichtenegger W: "Präoperative Prognoseeinschätzung von Patientinnen mit einem Mammakarzinom durch die farbkodierte Dopplersonographie. " Geburtsh Frauenheilkd. 1998, 58, S.6-12,

131 Linderholm B, Tavelin, B, Grankvist K, Henriksson R: "Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma. " J Clin Oncol. 1998, 16, S.3121-3128,

132 Overexpression of p53 and prognosis in breast cancer: "Overexpression of p53 and prognosis in breast cancer. " Cancer. 1993, 72, S.3641-3647,

133 Jonat W, Eidtmann H, Friedrichs K: "Prognosefaktoren beim Mammakarzinom. " Gynäkologe. 1994, 27, S.37-44,

134 Blohmer JU, Reinhardt M, Paepke S, Huttner C, Lichtenegger W, Fritzsch T: "Densitometry after injection of Levovist in the examination of focal breast lesions - preliminary results. " Eur J Ultrasound. 1997, 6 Suppl 2, S.S26,

135 Mross K, Hauns B, Häring B, Stephan P, Gastl G, Unger C: "Phase II trial with retinoid acid, interferon alpha and tamoxifen (RITA) in metastatic breast cancer patients. " J Cancer Res Clin Oncol. 1998, 124, S.123,

136 Marson LP, Kurian K, Dixon JM, Miller WR: "The effect of primary endocrine therapy on breast cancer angiogenesis. " Breast Cancer Res Treatm. 1998, 50, S.330,

137 Ernhardt B, Blohmer JU, Schuerenkaemper P, Lichtenegger W: "Correlation of Vascular Endothelial Growth Factor with Pathohistological Parameters in Breast Tumors: Preliminary Results. " Breast Cancer Res Treatm. 1999, 57, S.116,


[Titelseite] [Widmung] [1] [2] [3] [4] [5] [Bibliographie] [Anhang] [Selbständigkeitserklärung] [Danksagung]

© Die inhaltliche Zusammenstellung und Aufmachung dieser Publikation sowie die elektronische Verarbeitung sind urheberrechtlich geschützt. Jede Verwertung, die nicht ausdrücklich vom Urheberrechtsgesetz zugelassen ist, bedarf der vorherigen Zustimmung. Das gilt insbesondere für die Vervielfältigung, die Bearbeitung und Einspeicherung und Verarbeitung in elektronische Systeme.

DiML DTD Version 2.0
Zertifizierter Dokumentenserver
der Humboldt-Universität zu Berlin
HTML - Version erstellt am:
Tue Aug 15 12:11:56 2000