Höhn, Thomas: Effekte von Hyperoxie und Stickstoffmonoxid beim Neugeborenen



Abman SH, Kinsella JP, Schaffer MS, Wilkening RB. "Inhaled nitric oxide in the management of a premature newborn with severe respiratory distress and pulmonary hypertension" . Pediatrics 1993 ;92 :606-609

Ahdab-Barmada M, Moossy J, Nemoto EM, Lin MR. "Hyperoxia produces neuronal necrosis in the rat" . J Neuropathol Exp Neurol 1986 ;45 :233-46

Ahluwalia JS, Kelsall AW, Raine J, Rennie JM, Mahmood M, Oduro A, Latimer R, Pickett J, Higenbottam TW. "Safety of inhaled nitric oxide in premature neonates" . Acta Paediatrica 1994 ;83 :347-348

Akama KT, Van Eldik LJ. "Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signaling mechanism" . J Biol Chem 2000 ;275 :7918-24

Anderson DC, Abbassi O, Kishimoto TK, Koenig JM, McIntire LV, Smith CW. "Diminished lectin-, epidermal growth factor-, complement binding domain-cell adhesion molecule-1 on neonatal neutrophils underlies their impaired CD18-independent adhesion to endothelial cells in vitro" . J Immunol 1991 ;146 :3372-9

Änggard E. "Nitric oxide: mediator, murderer, and medicine" . Lancet 1994 ;343 :1199-1206

Appleby CJ, Towner RA. "Magnetic resonance imaging of pulmonary damage in the term and premature rat neonate exposed to hyperoxia" . Pediatr Res 2001 ; 50 :502-7

Asano K, Chee CB, Gaston B, Lilly CM, Gerard C, Drazen JM, Stamler JS. "Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells" . Proc Natl Acad Sci USA 1994 ;91 :10089-93

Barrington KJ, Finer NN. "Inhaled nitric oxide for respiratory failure in preterm infants (Cochrane Review). " Cochrane Database Syst Rev 2001 ;4 :CD000509

Bellamy TC, Wood J, Garthwaite J. "On the activation of soluble guanylyl cyclase by nitric oxide" . Proc Natl Acad Sci U S A 2002 ;99 :507-510

Benzing A, Beyer U, Kiefer P, Geiger K. "Inhaled nitric monoxide. Application and continuous measurement of concentration" . Anaesthesist 1993 ;42 :175-8

Berg M, James SP. "Human neutrophils release the Leu-8 lymph node homing receptor during cell activation" . Blood 1990 ;76 :2381-8

Bland RD. "Special considerations in oxygen therapy of infants and children" . Am Rev Respir Dis 1980 ;122 :45-54

Blomqvist H, Wickerts CJ, Andreen M, Ullberg U, Örtqvist Å, Frostell C. "Enhanced pneumonia resulution by inhalation of nitric oxide? " Acta Anaesthesiol Scand 1993 ;37 :110-4

Bohlinger I, Leist M, Barsig J, Uhlig S, Tiegs G, Wendel A. "Interleukin-1 and nitric oxide protect against tumor necrosis factor alpha-induced liver injury through distinct pathways. " Hepatology 1995 ;22 :1829-37

Bonfoco E, Krainc D, Ankarcrona M, Nicotera P, Lipton SA. "Apoptosis and necrosis: two "


"distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures." Proc Natl Acad Sci U S A 1995 ;92 :7162-6

Bonfoco E, Leist M, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P. "Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation. " J Neurochem 1996 ;67 :2484-93

Bromberger P, Lawrence JM, Braun D, Saunders B, Contreras R, Petitti DB. "The influence of intrapartum antibiotics on the clinical spectrum of early-onset group B streptococcal infection in term infants. " Pediatrics 2000 ;106 :244-50

Brooks SE, Gu X, Samuel S, Marcus DM, Bartoli M, Huang PL, Caldwell RB. "Reduced severity of oxygen-induced retinopathy in eNOS-deficient mice." Invest Ophthalmol Vis Sci 2001 ;42 :222-8

Brosnan CF, Lee SC, Liu J. "Regulation of inducible nitric oxide synthase expression in human glia: implications for inflammatory central nervous system diseases." Biochem Soc Trans 1997 ;25 :679

Brüne B, von Knethen A, Sandau KB. "Nitric oxide and its role in apoptosis." Eur J Pharmacol 1998 ;351 :261-72

Bührer C, Graulich J, Stibenz D, Dudenhausen JW, Obladen M. "L-selectin is down-regulated in umbilical cord blood granulocytes and monocytes of newborn infants with acute bacterial infection. " Pediatr Res 1994 ;36 :799-804

Chen Y, Whitney PL, Frank L. "Comparative responses of premature versus full-term newborn rats to prolonged hyperoxia." Pediatr Res 1994 ;35 :233-7

Chou JH, Greenberg JT, Demple B. "Posttranscriptional repression of Escherichia coli OmpF protein in response to redox stress: positive control of the micF antisense RNA by the soxRS locus." J Bacteriol 1993 ;175 :1026-31

Coeroli L, Renolleau S, Arnaud S, Plotkine D, Cachin N, Plotkine M, Ben-Ari Y, Charriaut-Marlangue C. "Nitric oxide production and perivascular tyrosine nitration following focal ischemia in neonatal rat." J Neurochem 1998 ;70 :2516-25

Cross AR, Jones OTG. "Enzyme mechanisms of superoxide production." Biochem Biophys Acta 1991 ;1057 :281-298

Cunha FQ, Assreuy J, Xu D, Charles I, Liew FY, Moncada S. "Repeated induction of nitric oxide synthase and leishmanicidal activity in murine macrophages." Eur J Immunol 1993 ;23 :1385-1388

Cunha FQ, Moss DW, Leal LM, Moncada S, Liew FY. "Induction of macrophage parasiticidal activity by Staphylococcus aureus and exotoxins through the nitric oxide synthesis pathway. " Immunology 1993 ;78 :563-7

Davidson D, Barefield ES, Kattwinkel J et al. "Inhaled nitric oxide for the early treatment of persistent pulmonary hypertension of the term newborn: a randomized, double- masked, placebo-controlled, dose-response, multicenter study. The I-NO/PPHN Study Group." Pediatrics 1998 ;101 :325-34

Demiryurek AT, Karamsetty MR, McPhaden AR, Wadsworth RM, Kane KA, MacLean MR. "Accumulation of nitrotyrosine correlates with endothelial NO synthase in pulmonary resistance arteries during chronic hypoxia in the rat." Pulm Pharmacol Ther 2000 ;13 :157-65

Derrico CA, Goodrum KJ. "Interleukin-12 and tumor necrosis factor alpha mediate innate production of gamma interferon by group B Streptococcus-treated splenocytes of severe combined immunodeficiency mice." Infect Immun 1996 ;64 :1314-20

Emeis M, Sonntag J, Willam C, Strauss E, Walka MM, Obladen M. "Acidosis activates "


"complement system in vitro. " Mediators Inflamm 1998 ;7 :417-20

Endo A, Ayusawa M, Minato M, Takada M, Takahashi S, Harada K. "Endogenous nitric oxide and endothelin-1 in persistent pulmonary hypertension of the newborn." Eur J Pediatr 2001 ;160 :217-22

Eng RH, Hsieh A, Smith SM. "Antibiotic killing of bacteria: comparison of bacteria on surfaces and in liquid, growing and nongrowing." Chemotherapy 1995 ;41 :113-20

Estevez AG, Spear N, Thompson JA, Cornwell TL, Radi R, Barbeito L, Beckman JS. "Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor." J Neurosci 1998 ;18 :3708-14

Ferguson DA Jr, Veringa EM, Mayberry WR, Overbeek BP, Lambe DW Jr, Verhoef J. "Bacteroides and Staphylococcus glycocalyx: chemical analysis, and the effects on chemiluminescence and chemotaxis of human polymorphonuclear leucocytes." Microbios 1992 ;69 :53-65

Finer NN, Barrington KJ. "Nitric oxide for respiratory failure in infants born at or near term (Cochrane Review). " Cochrane Database Syst Rev 2001 ;4 :CD000399

Forman HJ, Torres M. "Redox signaling in macrophages." Mol Aspects Med 2001 ;22 :189-216

Fortenberry JD, Marolda JR, Anderson DC, Smith CW, Mariscalco MM. "CD18-dependent and L-selectin-dependent neutrophil emigration is diminished in neonatal rabbits. " Blood 1994 ;84 :889-97

Fortenberry JD, Bhardwaj V, Niemer P, Cornish JD, Wright JA, Bland L. "Neutrophil and cytokine activation with neonatal extracorporeal membrane oxygenation." J Pediatr 1996 ;128 :670-8

Fraticelli A, Serrano CV Jr, Bochner BS, Capogrossi MC, Zweier JL. "Hydrogen peroxide and superoxide modulate leukocyte adhesion molecule expression and leukocyte endothelial adhesion. " Biochim Biophys Acta 1996 ;1310 :251-9

Frostell C, Fratacci MD, Wain JC, Jones R, Zapol WM. "Inhaled nitric oxide: a selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction." Circulation 1991 ;83 :2038-2047

Furchgott RF, Zawadzki JV. "The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. " Nature 1980 ;288 :373-376

Furchgott RF, Cherry PD, Zawadzki JV, Jothianandan D. "Endothelial cells as mediators of vasodilation of arteries. " J Cardiovasc Pharmacol 1984 ;6 :S336-S343

Furchgott RF, Vanhoutte PM. "Endothelium-derived relaxing and contracting factors." FASEB J 1989 ;3 :2007-2018

Goodrum KJ, McCormick LL, Schneider B. "Group B streptococcus-induced nitric oxide production in murine macrophages is CR3 (CD11b/CD18) dependent." Infect Immun 1994 ;62 :3102-7

Goodrum KJ, Dierksheide J, Yoder BJ. "Tumor necrosis factor alpha acts as an autocrine second signal with gamma interferon to induce nitric oxide in group B streptococcus-treated macrophages. " Infect Immun 1995 ;63 :3715-7

Green D, Kroemer G. "The central executioners of apoptosis: caspases or mitochondria? " Trends Cell Biol 1998 ;8 :267-71

Heneka MT, Dumitrescu L, Loschmann PA, Wullner U, Klockgether T. "Temporal, regional, and cell-specific changes of iNOS expression after intrastriatal microinjection of interferon gamma "


"and bacterial lipopolysaccharide." J Chem Neuroanat 2000 ;18 :167-79

Heneka MT, Feinstein DL. "Expression and function of inducible nitric oxide synthase in neurons. " J Neuroimmunol 2001 ;114 :8-18

Hibbs JB Jr, Taintor RR, Vavrin Z. "Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite." Science 1987 ;235 :473-476

Hibbs JB Jr, Taintor RR, Vavrin Z, Rachlin EM. "Nitric oxide: a cytotoxic activated macrophage effector molecule. " Biochem Biophys Res Commun 1988 ;157 :87-94

Hirsch EC, Hunot S, Damier P, Faucheux B. "Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration?" Ann Neurol 1998 ;44 :S115-20

Hirsch T, Marchetti P, Susin SA, Dallaporta B, Zamzami N, Marzo I, Geuskens M, Kroemer G. "The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death." Oncogene 1997 ;15 :1573-81

Hoehn T, Krause M, Wildberg A, Pringsheim W, Leititis JU. "Reversal of a right-left shunt and permanent improvement of oxygenation by inhalation of nitrogen monoxide in a premature infant with lung hypoplasia and asphyxia." Z Geburtshilfe Neonatol 1997 ;201 :105-7

Hoehn T, Krause M, Hentschel R. "High-frequency ventilation augments the effect of inhaled nitric oxide in persistent pulmonary hypertension of the newborn." Eur Respir J 1998 ;11 :234-8

Hoehn T, Huebner J, Paboura E, Krause M, Leititis JU. "Effect of therapeutic concentrations of nitric oxide on bacterial growth in vitro." Crit Care Med 1998 ;26 :1857-62

Hoehn T, Krause MF, Buhrer C. "Inhaled nitric oxide in premature infants--a meta-analysis. " J Perinat Med 2000 ;28 :7-13

Hoehn T, Felderhoff U, Altstaedt J, Obladen M, Bührer C. "Hyperoxia- and hypoxia-mediated activation of polymorphonuclear leukocytes: a comparison of cord and adult venous blood. " Resuscitation 2001 ;51 :63-8

Ignarro LJ, Byrns RE, Buga GM, Wood KS. "Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. " Circ Res 1987 ;61 :866-879

Ikeno S, Nagata N, Yoshida S, Takahashi H, Kigawa J, Terakawa N. "Immature brain injury via peroxynitrite production induced by inducible nitric oxide synthase after hypoxia-ischemia in rats." J Obstet Gynaecol Res 2000 ;26 :227-34

Ikonomidou C, Bosch F, Miksa M, Bittigau P, Vockler J, Dikranian K, Tenkova TI, Stefovska V, Turski L, Olney JW. "Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain." Science 1999 ;283 :70-4

Ischiropoulos H, Zhu L, Chen J, Tsai M, Martin JC, Smith CD, Beckman JS. "Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase." Arch Biochem Biophys 1992 ;298 :431-437

Javeshghani D, Magder S. "Presence of nitrotyrosine with minimal inducible nitric oxide synthase induction in lipopolysaccharide-treated pigs." Shock 2001 ;16 :304-11

Kattwinkel J, Niermeyer S, Nadkarni V, Tibballs J, Phillips B, Zideman D, Van Reempts P, Osmond M. "Resuscitation of the newly born infant: an advisory statement from the Pediatric Working Group of the International Liaison Committee on Resuscitation. " Resuscitation 1999 ;40 :71-88

Keeney SE, Mathews MJ, Haque AK, Schmalstieg FC. "Comparison of pulmonary neutrophils in the adult and neonatal rat after hyperoxia. " Pediatr Res 1995; 38 :857-63


Kim PK, Zamora R, Petrosko P, Billiar TR. "The regulatory role of nitric oxide in apoptosis. " Int Immunopharmacol 2001 ;1 :1421-41

Kim YM, Talanian RV, Billiar TR. "Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms." J Biol Chem 1997 ;272 :31138-48

Kinsella JP, Neish SR, Shaffer E, Abman SH. "Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn." Lancet 1992 ;340 :819-820

Kinsella JP, Truog WE, Walsh WF et al. "Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn. " J Pediatr 1997 ;131 :55-62

Kirsch M, Lehnig M, Korth HG, Sustmann R, de Groot H. "Inhibition of peroxynitrite-induced nitration of tyrosine by glutathione in the presence of carbon dioxide through both radical repair and peroxynitrate formation. " Chemistry 2001 ;7 :3313-20

Kishimoto TK, Jutila MA, Berg EL, Butcher EC. "Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors." Science 1989 ;245 :1238-41

Kobzik L, Bredt DS, Lowenstein CJ, Drazen J, Gaston B, Sugarbaker D, Stamler JS. "Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization." Am J Respir Cell Mol Biol 1993 ;9 :371-7

Koenig JM, Simon J, Anderson DC, Smith E, Smith CW. "Diminished soluble and total cellular L-selectin in cord blood is associated with its impaired shedding from activated neutrophils. " Pediatr Res 1996 ;39 :616-21

Kojima H, Nakatsubo N, Kikuchi K, Urano Y, Higuchi T, Tanaka J, Kudo Y, Nagano T. "Direct evidence of NO production in rat hippocampus and cortex using a new fluorescent indicator: DAF-2 DA." Neuroreport 1998 ;9 :3345-8

Kolker S, Ahlemeyer B, Huhne R, Mayatepek E, Krieglstein J, Hoffmann GF. "Potentiation of 3-hydroxyglutarate neurotoxicity following induction of astrocytic iNOS in neonatal rat hippocampal cultures." Eur J Neurosci 2001 ;13 :2115-22

Koppenol WH, Moreno JJ, Pryor WA, Ischiropoulos H, Beckman JS. "Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide." Chem Res Toxicol 1992 ;5 :834-42

Kosarikov DN, Lee JM, Uversky VN, Counts Gerber N. "Role of conformational changes in the heme-dependent regulation of human soluble guanylate cyclase." J Inorg Biochem 2001 ;87 :267-76

Kotecha S, Silverman M, Shaw RJ, Klein N. "Soluble L-selectin concentration in bronchoalveolar lavage fluid obtained from infants who develop chronic lung disease of prematurity. " Arch Dis Child Fetal Neonatal Ed 1998 ;78 :F143-7

Kröncke KD, Fehsel K, Suschek C, Kolb-Bachofen V. "Inducible nitric oxide synthase-derived nitric oxide in gene regulation, cell death and cell survival." Int Immunopharmacol 2001 ;1 :1407-1420

Lee C, Miura K, Liu X, Zweier JL. "Biphasic regulation of leukocyte superoxide generation by nitric oxide and peroxynitrite." J Biol Chem 2000 ;275 :38965-72

Leist M, Volbracht C, Kuhnle S, Fava E, Ferrando-May E, Nicotera P. "Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide. " Mol Med 1997 ;3 :750-64

Leist M, Fava E, Montecucco C, Nicotera P. "Peroxynitrite and nitric oxide donors induce neuronal apoptosis by eliciting autocrine excitotoxicity." Eur J Neurosci 1997 ;9 :1488-98

Leist M, Single B, Castoldi AF, Kuhnle S, Nicotera P. "Intracellular adenosine triphosphate "


"(ATP) concentration: a switch in the decision between apoptosis and necrosis. " J Exp Med 1997 ;185 :1481-6

Leviton A, Paneth N, Reuss ML, Susser M, Allred EN, Dammann O, Kuban K, Van Marter LJ, Pagano M, Hegyi T, Hiatt M, Sanocka U, Shahrivar F, Abiri M, Disalvo D, Doubilet P, Kairam R, Kazam E, Kirpekar M, Rosenfeld D, Schonfeld S, Share J, Collins M, Genest D, Shen-Schwarz S. Maternal infection, fetal inflammatory response, and brain damage in very low birth weight infants. Developmental Epidemiology Network Investigators. Pediatr Res 1999 ;46 :566-75

Liaudet L, Soriano FG, Szabo C. Biology of nitric oxide signaling. Crit Care Med 2000 ;28(4 Suppl) :N37-52

Liochev SI, Fridovich I. Fumarase C, the stable fumarase of Escherichia coli, is controlled by the soxRS regulon. Proc Natl Acad Sci U S A 1992 ;89 :5892-6

Liochev SI, Hausladen A, Beyer WF Jr, Fridovich I. NADPH: ferredoxin oxidoreductase acts as a paraquat diaphorase and is a member of the soxRS regulon. Proc Natl Acad Sci U S A 1994 ;91 :1328-31

Mancinelli RL, McKay CP. Effects of nitric oxide and nitrogen dioxide on bacterial growth. Appl Environ Microbiol 1983 ;46 :198-202

Mannick JB, Asano K, Izumi K, Kieff E, Stamler JS. Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation. 1994 ;79 :1137-46

Martin TR, Ruzinski JT, Wilson CB, Skerrett SJ. Effects of endotoxin in the lungs of neonatal rats: age-dependent impairment of the inflammatory response. J Infect Dis 1995 ;171 :134-44

Melino G, Bernassola F, Knight RA, Corasaniti MT, Nistico G, Finazzi-Agro A. S-nitrosylation regulates apoptosis. Nature 1997 ;388 :432-3

Minc-Golomb D, Yadid G, Tsarfaty I, Resau JH, Schwartz JP. In vivo expression of inducible nitric oxide synthase in cerebellar neurons. J Neurochem 1996 ;66 :1504-9

Mildenberger E, Siegel G, Versmold HT. Oxygen-dependent regulation of membrane potential and vascular tone of human umbilical vein. Am J Obstet Gynecol 1999 ;181 :696-700

Minghetti L, Levi G. "Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. " Prog Neurobiol 1998 ;54 :99

Moncada S. "The 1991 Ulf von Euler Lecture. The L-arginine: nitric oxide pathway." Acta Physiol Scand 1992 ;145 :201-27

Moncada S, Higgs A. "The L-arginine-nitric oxide pathway." N Engl J Med 1993 ;329 :2002-12

Murad F, Waldman SA, Fiscus RR, Rapoport RM. "Regulation of cyclic GMP synthesis and the interactions with calcium. " J Cardiovasc Pharmacol 1986 ;8 :S57-S60

Murphy S, Simmons ML, Agullo L, Garcia A, Feinstein DL, Galea E, Reis DJ, Minc-Golomb D, Schwartz JP. "Synthesis of nitric oxide in CNS glial cells." Trends Neurosci 1993 ;16 :323

Nakayama DK, Geller DA, Lowenstein CJ, Chern HD, Davies P, Pitt BR, Simmons RL, Billiar TR. "Cytokines and lipopolysaccharide induce nitric oxide synthase in cultured rat pulmonary artery smooth muscle." Am J Respir Cell Mol Biol 1992 ;7 :471-6

Nicotera P, Leist M, Manzo L. "Neuronal cell death: a demise with different shapes." Trends Pharmacol Sci 1999 ;20 :46-51

Niermeyer S, Kattwinkel J, Van Reempts P, Nadkarni V, Phillips B, Zideman D, Azzopardi D, Berg R, Boyle D, Boyle R, Burchfield D, Carlo W, Chameides L, Denson S, Fallat M, Gerardi M, Gunn A, Hazinski MF, Keenan W, Knaebel S, Milner A, Perlman J, Saugstad OD, Schleien C, Solimano A, Speer M, Toce S, Wiswell T, Zaritsky A. "International Guidelines for Neonatal "


"Resuscitation: An excerpt from the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: International Consensus on Science. Contributors and Reviewers for the Neonatal Resuscitation Guidelines." Pediatrics 2000 ;106 :E29

North AJ, Moya FR, Mysore MR, Thomas VL, Wells LB, Wu LC, Shaul PW. "Pulmonary endothelial nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia." Am J Respir Cell Mol Biol 1995 ;13 :676-82

Nunoshiba T, DeRojas-Walker T, Tannenbaum SR, Demple B. Nunoshiba T, DeRojas-Walker T, Tannenbaum SR, Demple B. "Roles of nitric oxide in inducible resistance of Escherichia coli to activated murine macrophages." Infect Immun 1995 ;63 :794-8

O'Donovan DJ, Fernandes CJ. "Mitochondrial glutathione and oxidative stress: implications for pulmonary oxygen toxicity in premature infants." Mol Genet Metab 2000 ;71 :352-8

Palmer RMJ, Ferrige AG, Moncada S. "Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor." Nature 1987 ;327 :524-526

Palmer RMJ, Rees DD, Ashton DS, Moncada S. "L-arginine is the physiological precursor for the formation of nitric oxide in endothelium dependent relaxation. " Biochem Biophys Res Comm 1988 ;153 :1251-1256

Peliowski A, Finer NN, Etches PC, Tierney AJ, Ryan CA. "Inhaled nitric oxide for premature infants after prolonged rupture of the membranes. " J Pediatr 1995 ; 126 :450-453

Pepke-Zaba J, Higenbottam T. "Inhaled nitric oxide as a cause of selective pulmonary vasodilation in pulmonary hypertension." Lancet 1991 ;338 :1173-1174

Pierangeli SS, Sonnenfeld G. "Treatment of murine macrophages with murine interferon-gamma and tumour necrosis factor-alpha enhances uptake and intracellular killing of Pseudomonas aeruginosa." Clin Exp Immunol 1993 ;93 :165-71

Raghuram N, Fortenberry JD, Owens ML, Brown LA. "Effects of exogenous nitric oxide and hyperoxia on lung fibroblast viability and DNA fragmentation." Biochem Biophys Res Commun 1999 ;262 :685-91

Rebuck N, Gibson A, Finn A. "Neutrophil adhesion molecules in term and premature infants: normal or enhanced leucocyte integrins but defective L-selectin expression and shedding. " Clin Exp Immunol 1995 ;101 :183-9

Ridings PC, Windsor AC, Jutila MA, Blocher CR, Fisher BJ, Sholley MM, Sugerman HJ, Fowler AA 3rd. "A dual-binding antibody to E- and L-selectin attenuates sepsis-induced lung injury. " Am J Respir Crit Care Med 1995 ;152 :247-53

Robbins CG, Davis JM, Merritt TA, Amirkhanian JD, Sahgal N, Morin FC III, Horowitz S. "Combined effects of nitric oxide and hyperoxia on surfactant function and pulmonary inflammation." Am J Physiol 1995; 269 :L545-50

Robbins RA, Springall DR, Warren JB, Kwon OJ, Buttery LD, Wilson AJ, Adcock IM, Riveros-Moreno V, Moncada S, Polak J, et al. "Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation." Biochem Biophys Res Commun 1994 ;198 :835-43

Roberts JD, Polaner DM, Lang P, Zapol WM. "Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. " Lancet 1992 ;340 :818-819

Roberts JD Jr, Fineman JR, Morin FC 3rd, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann MA, Zapol WM. "Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group. " N Engl J Med 1997 ;336 :605-10

Rupp ME, Ulphani JS, Fey PD, Bartscht K, Mack D. "Characterization of the importance of "


"polysaccharide intercellular adhesin/hemagglutinin of Staphylococcus epidermidis in the pathogenesis of biomaterial-based infection in a mouse foreign body infection model. " Infect Immun 1999 ;67 :2627-32

Seekamp A, Till GO, Mulligan MS, Paulson JC, Anderson DC, Miyasaka M, Ward PA. "Role of selectins in local and remote tissue injury following ischemia and reperfusion." Am J Pathol 1994 ;144 :592-8

Sethi S, Sharma P, Dikshit M. "Nitric oxide- and oxygen-derived free radical generation from control and lipopolysaccharide-treated rat polymorphonuclear leukocyte. " Nitric Oxide 2001 ;5 :482-93

Shaul PW, North AJ, Wu LC, Wells LB, Brannon TS, Lau KS, Michel T, Margraf LR, Star RA. "Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epithelium." J Clin Invest 1994 ;94 :2231-6

Shesely EG, Maeda N, Kim HS, Desai KM, Krege JH, Laubach VE, Sherman PA, Sessa WC, Smithies O. "Elevated blood pressures in mice lacking endothelial nitric oxide synthase. " Proc Natl Acad Sci U S A 1996 ;93 :13176-81

Sinz EH, Kochanek PM, Dixon CE, Clark RS, Carcillo JA, Schiding JK, Chen M, Wisniewski SR, Carlos TM, Williams D, DeKosky ST, Watkins SC, Marion DW, Billiar TR. "Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice." J Clin Invest 1999 ;104 :647-56

Smith JB, Tabsh KM. "Fetal neutrophils and eosinophils express normal levels of L-selectin. " Pediatr Res 1993 ;34 :253-7

Sokol J, Jacobs SE, Bohn D. "Inhaled nitric oxide for acute hypoxemic respiratory failure in children and adults. " Cochrane Database Syst Rev 2000 ;4 :CD002787

Steudel W, Scherrer-Crosbie M, Bloch KD, Weimann J, Huang PL, Jones RC, Picard MH, Zapol WM. "Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3. " J Clin Invest 1998 ;101 :2468-77

Stibenz D, Buhrer C. "Down-regulation of L-selectin surface expression by various leukocyte isolation procedures." Scand J Immunol 1994 ;39 :59-63

Stout RD, Li Y, Miller AR, Lambe DW Jr. "Staphylococcal glycocalyx activates macrophage prostaglandin E2 and interleukin 1 production and modulates tumor necrosis factor alpha and nitric oxide production." Infect Immun 1994 ;62 :4160-6

Subhedar NV, Ryan SW, Shaw NJ. "Open randomised controlled trial of inhaled nitric oxide and early dexamethasone in high risk preterm infants." Arch Dis Child Fetal Neonatal Ed 1997 ;77 :F185-90

Taglialatela G, Perez-Polo JR, Rassin DK. "Induction of apoptosis in the CNS during development by the combination of hyperoxia and inhibition of glutathione synthesis. " Free Radic Biol Med 1998 ;25 :936-42

Tenneti L, D'Emilia DM, Lipton SA. "Suppression of neuronal apoptosis by S-nitrosylation of caspases. " Neurosci Lett 1997 ;236 :139-42

The Neonatal Inhaled Nitric Oxide Study Group. "Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure." N Engl J Med 1997 ;336 :597-604

Török C, Lundahl J, Hed J, Lagercrantz H. "Diversity in regulation of adhesion molecules (Mac-1 and L-selectin) in monocytes and neutrophils from neonates and adults. " Arch Dis Child 1993 ;68 :561-5

Vasileva SV, Stupakova MV, Lobysheva II, Mikoyan VD, Vanin AF. "Activation of the "


"Escherichia coli SoxRS-regulon by nitric oxide and its physiological donors." Biochemistry (Mosc) 2001 ;66 :984-8

Wakita T, Shintani F, Yagi G, Asai M, Nozawa S. "Combination of inflammatory cytokines increases " nitrite and nitrate levels in the paraventricular nucleus of conscious rats. Brain Res 2001;905:12-20

Weinberger B, Weiss K, Heck DE, Laskin DL, Laskin JD. "Pharmacologic therapy of persistent pulmonary hypertension of the newborn. " Pharmacol Ther 2001 ;89 :67-79

Weisz A, Cicatiello L. "Regulation of the mouse inducible-type nitric oxide synthase gene promoter by interferon-gamma, bacterial lipopolysaccharide and NG-monomethyl-L-arginine." Biochem J 1996 ;316 :209-215

Wink DA, Mitchell JB. "Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide." Free Radic Biol Med 1998 ;25 :434-56

Zhang H, Squadrito GL, Pryor WA. "The mechanism of the peroxynitrite-carbon dioxide reaction probed using tyrosine. " Nitric Oxide 1997 ;1 :301-7


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Thu Dec 5 13:35:52 2002