Kamradt, Thomas: Aktivierung und Differenzierung von T-Lymphozyten durch Infektion und Autoimmunität

35

Literatur

Harris, H.F.: "A case of diabetes quickly following mumps. On the pathological alterations of salivary glands, closely resembling those found in pancreas, in a case of diabetes mellitus," Boston Med Surg J, 1899, CXL, S. 465-469,

Gibofsky, A.; Kerwar, S.; Zabriskie, J. B.: "Rheumatic fever. The relationships between host, microbe, and genetics," Rheum Dis Clin North Am, 1998, 24, S. 237-59,

Panitch, H.S.: "Influence of infection on exacerbations of multiple sclerosis," Ann Neurol, 1994, 36, S. S25-S28,

Markowitz, A. S.: "Streptococcal-related glomerulonephritis in the Rhesus monkey," Transplant Proc, 1969, 4, 1, S. 985-91,

Fujinami, R.S.; Oldstone, M.B.: "Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity," Science, 1985, 230, S. 1043-1045,

Lafaille, J.J.; Nagashima, K.; Katsuki, M.; Tonegawa, S.: "High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice," Cell, 1994, 78, S. 399-408,

Oldstone, M.B.A.: "Molecular mimicry and immune-mediated diseases," FASEB J., 1998, 12, S. 1255-1265,

Kitze, B.; Pette, M.; Rohrbach, E.; Stadt, D.; Kappos, L.; Wekerle, H.: "Myelin-specific T lymphocytes in multiple sclerosis patients and healthy individuals," J Neuroimmunol, 1988, 20, S. 237,

Naquet, P.; Ellis, J.; Tibensky, D.; Kenshole, A.; Singh, B.; Hodges, R.; Delovitch, T. L.: "T cell autoreactivity to insulin in diabetic and related non-diabetic individuals," J Immunol, 1988, 140, S. 2569-78,

Souroujon, M.; White-Scharf, M.E.; Andreschwartz, J.; Gefter, M. L.; Schwartz, R. S.: "Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice," J Immunol, 1988, 12, 140, S. 4173-9,

Tough, D.F.; Borrow, P.; Sprent, J.: "Induction of bystander T cell proliferation by viruses and type I interferon in vivo.," Science, 1996, S. 1947- 1950,

Ehl, S.; Hombach, J.; Aichele, P.; Hengartner, H.; Zinkernagel, R. M.: "Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model," J Exp Med, 1997, 185, S. 1241-51,

Butz, E. A.; Bevan, M. J.: "Massive expansion of antigen-specific CD8+ T cells during an acute virus infection," Immunity, 1998, 8, S. 167-75, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.immunity.com/cgi/content/full/8/2/167

Murali-Krishna, K.; Altman, J. D.; Suresh, M.; Sourdive, D. J.; Zajac, A. J.; Miller, J. D.; Slansky, J.; Ahmed, R.: "Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection," Immunity, 1998, 8, S. 177-87, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.immunity.com/cgi/content/full/8/2/177


36

Tough, D.F.; Sun, S.; Sprent, J.: "T cell stimulation in vivo by lipopolysaccharide (LPS)," J Exp Med, 1997, 185, S. 2089-2094,

Infante-Duarte, C.; Kamradt, T.: "Lipopeptides of Borrelia burgdorferi outer surface proteins induce Th1 phenotype development in ab TCR transgenic mice," Infection and Immunity, 1997, 10, 65, S. 4094-4099,

Kamradt, T.; Soloway, P.D.; Perkins, D.L.; Gefter, M.L.: "Pertussis toxin prevents the induction of peripheral T cell anergy and enhances the T cell response to an encephalitogenic peptide of myelin basic protein," JI, 1991, 147, S. 3296-3302,

Klinman, D. M.; Yi, A. K.; Beaucage, S. L.; Conover, J.; Krieg, A. M.: "CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma," Proc Natl Acad Sci U S A, 1996, 93, S. 2879-83,

Cella, M.; Salio, M.; Sakakibara, Y.; Langen, H.; Julkunen, I.; Lanzavecchia, A.: "Maturation, activation, and protection of dendritic cells induced by double-stranded RNA," J Exp Med, 1999, 5, 189, S. 821-9, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jem.org/cgi/content/full/189/5/821

White, J.; Herman, A.; Pullen, A. M.; Kubo, R.; Kappler, J. W.; Marrack, P.: "The V beta-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice," Cell, 1989, 1, 56, S. 27-35,

Perron, H.; Garson, J. A.; Bedin, F.; Beseme, F.; Paranhos-Baccala, G.; Komurian-Pradel, F.; Mallet, F.; Tuke, P. W.; Voisset, C.; Blond, J. L.; Lalande, B.; Seigneurin, J. M.; Mandrand, B.: "Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis," Proc Natl Acad Sci U S A, 1997, 14, 94, S. 7583-8, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.pnas.org/cgi/content/full/94/14/7583

Kawabe, Y.; Ochi, A.: "Programmed cell death and extrathymic reduction of Vb8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B," Nature, 1991, 349, S. 245-248,

Damian, R.T.: "Molecular mimicry: antigen sharing by parasite and host and its consequences.," Am Nat, 1964, 98, S. 129-149,

Jahnke, U.; Fischer, E.H.; Alvord, E.C. Jr.: "Sequence homology between certain viral proteins and proteins related to encephalomyelitis and neuritis," Science, 1985, 229, S. 282-284,

Kamradt, T.; Krause, A.; Priem, S.; Burmester, G.-R.: "Lyme Arthritis. Klinik, Diagnostik und Therapie," Dt. Ärztebl, 1998, 95, S. A-214-219,

Steere, A.C.; Schoen, R.T.; Taylor, E.: "The clinical evolution of Lyme arthritis," Annals of Internal Medicine, 1987, 107, S. 725-731,

Steere, A.C.; Gibofsky, A; Patarroyo, M.E.; Winchester, R.J.; Hardin, J.A.; Malawista, S.E.: "Chronic Lyme arthritis. Clinical and immunogenetic differentiation from rheumatoid arthritis," Annals of Internal Medicine, 1979, 90, S. 896-901,

Steere, A.C.; Levin, R.E.; Molloy, P.J.; Kalish, R.A.; Abraham, J.H., III; Liu, N.Y.; Schmid, C.H.: "Treatment of Lyme arthritis," Arthritis and Rheumatism, 1994, 37, S. 878-888,


37

Burmester, G.R.; Daser, A.; Kamradt, T.; Krause, A.; Mitchison, N.A.; Sieper, J.; Wolf, N.: "The immunology and immunopathology of reactive arthritides," ARI, 1995, 13, S. 229-250,

Kamradt, T.; Krause, A.; Burmester, G.-R.: "A role for T cells in the pathogenesis of treatment-resistant Lyme arthritis?," Molecular Medicine, 1995, 1, S. 486-490,

Nocton, J.J.; Dressler, F.; Rutledge, B.J.; Rys, P.N.; Persing, D.H.; Steere, A.C.: "Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid in Lyme arthritis," NEJM, 1994, 330, S. 229-234,

Priem, S. ; Rittig, M.G:; Kamradt, T.; Wolbart, K.; Burmester, G.R.; Krause, A.: "Detection of Borrelia burgdorferi by polymerase chain reaction in synovial membrane, but not in synovial fluid from patients with persisting Lyme arthritis after antibiotic therapy," ARD, 1998, 57, S. 118-121,

Steere, A.C.; Dwyer, E.D.; Winchester, R.: "Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles," New England Journal of Medicine, 1990, 323, S. 219-223,

Zamvil, S.S.; Steinman, L.: "The T lymphocyte in experimental allergic encephalitis," Annual Review of Immunology, 1990, 8, S. 579-621,

Steinman, L.: "Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system," Cell, 1996, 85, S. 299-302,

Zamvil, S. S.; Mitchell, D. J.; Moore, A. C.; Kitamura, K.; Steinman, L.; Rothbard, J. B.: "T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis," Nature, 1986, 6094, 324, S. 258-60,

Olivares-Villagomez, D.; Wang, Y.; Lafaille, J. J.: "Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis," J Exp Med, 1998, 10, 188, S. 1883-94, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jem.org/cgi/content/full/188/10/1883

Abbas, A.K.; Murphy, K.M.; Sher, A.: "Functional diversity of helper T lymphocytes," Nature, 1996, 383, S. 787-793,

Kamradt, T.; Burmester, G.-R.: "Cytokines and arthritis: is the Th1/Th2 paradigm useful for understanding pathogenesis?," JR, 1998, 1, 25, S. 6-8,

Infante Duarte, C.; Kamradt, T.: "Th1/Th2 balance in infection," Springer Semin Immunopathol, 1999, 3, 21, S. 317-338,

Murphy, K.M.; Ouyang, W.; Farrar, J.D.; Yang, J.; Ranganath, S.; Asnagli, H.; Afkarian, M.; Murphy, T.L.: "Signalling and transcription in T helper development," ARI, 2000, 18, S. 451-494,

Firestein, G.S.; Roeder, W.D.; Laxer, J.A.; Townsend, K.S.; Weaver, C.T.; Hom, J.T.; Linton, J.; Torbett, B.E.; Glasebrook, A.L.: "A new murine CD4+ cell subset with an unrestricted cytokine profile," JI, 1989, 143, S. 518-525,

Chen, Y.; Kuchroo, V.K.; Inobe, J.-L.; Hafler, D.A.; Weiner, H.L.: "Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis," Science, 1994, 265, S. 1237-1240,


38

Groux, H; O'Garra, A.; Bigler, M.; Rouleau, M.; Antonenko, S.; de Vries, J.E.; Roncarolo, M.G.: "A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis," Nature, 1997, 389, S. 737-742,

Löhning, M.; Grogan, J.L.; Coyle, A.J.; Meisel, C.; Yazdanbakhsh, M.; Gutierrez-Ramos, J.C.; Radbruch, A.; Kamradt, T.: "Expression of T1/ST2 is enhanced on CD4+ T cells from schistosome egg-induced granulomas: Analysis of T helper cell cytokine co-expression ex vivo.," JI, 1999, 162, S. 3882-3889,

Keffer, J. ; Probert, L. ; Cazlaris, H.; Georgopoulos, S. ; Kaslaris, E. ; Kioussis, D. ; Kollias, G.: "Transgenic mice expressing human tumor necrosis factor: a predictive genetic model of arthritis," EMBO J, 1991, 10, S. 4025-4031,

Zhao, Z.-S.; Granucci, F.; Yeh, L.; Schaffer, P.A.; Cantor, H.: "Molecular mimicry by Herpes Simplex Virus-Type 1: autoimmune disease after viral infection," Science, 1998, 279, S. 1344-1347,

Gangappa, S.; Babu, J.; Thomas, J.; Daheshia, M.; Rouse, B.: "Virus-induced immunoinflammatory lesions in the absence of viral antigen recognition," JI, 1998, 161, S. 4289-4300,

Yin, Z.; Braun, J.; Neure, L.; Wu, P.; Krause, A.; Kamradt, T.; Sieper, J.: "T cell cytokine pattern in the joints of patients with Lyme arthritis and its regulation by cytokines and anticytokines.," Arthr Rheum, 1997, 40, S. 69-79,

Infante-Duarte, C.; Horton, H.F.; Byrne, M.C.; Kamradt, T.: "Microbial lipopeptides induce the production of IL-17 in T helper (Th) cells," JI, 2000, 165, S. 6107-6115,

Sallusto, F.; Lenig, D.; Mackay, C.R.; Lanzavecchia, A.: "Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes," JEM, 1998, 187, S. 875-883,

Xu, D.; Chan, W.L.; Leung, B.P.; Huang, F; Wheeler, R.; Piedrafita, D.; Robinson, J.H.; Liew, F.Y.: "Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells," JEM, 1998, 187, S. 787-794,

Löhning, M.; Stroehmann, A.; Coyle, A.J.; Grogan, J.L.; Lin, S.; Gutierrez-Ramos, J.C.; Levinson, D.; Radbruch, A.; Kamradt, T.: "T1/ST2 is preferentially expressed on murine Th2 cells, independent of IL-4, IL-5, and IL-10, and important for Th2 effector function," PNAS, 1998, 95, S. 6930-6935,

Coyle, A.J.; Lloyd, C.; Tian, J.; Nguyen, T.; Eriksson, C.; Wang, L.; Ottoson, P.; Persson, P.; Delaney, T.; Lehar, S.; Lin, S.; Poisson, L.; Meisel, C.; Kamradt, T.; Bjerke, T.; Levinson, D.; Gutierrez-Ramos, J.C.: "Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses," JEM, 1999, 9, 190, S. 895-902,

Meisel, C.; Bonhagen, K.; Löhning, M.; Coyle, A.C.; Guttierez-Ramos, J.C.; Radbruch, A. ; Kamradt, T.: "Regulation and function of T1/ST2-expression on CD4+ T cells: Induction of type 2 cytokine production by T1/ST2-crosslinking," JI, 2001, 166, S. 3143-3150,


39

Bucy, R. P.; Panoskaltsis-Mortari, A.; Huang, G. Q.; Li, J.; Ross, M.; Russel, J.H.; Karr, L.; Murphy, K. M.; Weaver, C. T.: "Heterogeneity of single cell cytokine gene expression in clonal T cell populations.," JEM, 1994, 180, S. 1251-1262,

Kelso, A.; Groves, P.; Troutt, A. B.; Francis, K.: "Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like response in vivo," EJI, 1995, 25, S. 1168-1175,

Assenmacher, M.; Schmitz, J.; Radbruch, A.: "Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-g and interleukin-4-expressing cells.," EJI, 1994, 24, S. 1097-1101,

Openshaw, P.; Murphy, E. E.; Hosken, N. A.; Maino, V.; Davis, K.; Murphy, K.; O'Garra, A.: "Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations," JEM, 1995, 5, 182, S. 1357-1367,

Murphy, E.; Shibuya, K.; Hosken, N.; Openshaw, P.; Maino, V.; Davis, K.; Murphy, K.; O'Garra, A.: "Reversibility of T helper 1 and 2 populations is lost after long-term stimulation," JEM, 1996, 183, S. 901-913,

Sornasse, T.; Larenas, P.V.; Davis, K.A:; de Vries, J.E.; Yssel, H.: "Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level," JEM, 1996, 184, S. 473-483,

Assenmacher, M.; Löhning, M.; Scheffold, A.; Manz, R.; Schmitz, J.; Radbruch, A.: "Sequential production of IL-2, IFN-g and IL-10 by individual Th lymphocytes," EJI, 1998, 28, S. 1534-1543,

Lengl-Janßen, B.; Strauss, A.F.; Steere, A.C.; Kamradt, T.: "The T helper cell response in Lyme arthritis: Differential recognition of Borrelia burgdorferi outer surface protein A (OspA) in patients with treatment-resistant or treatment-responsive Lyme arthritis," Journal of Experimental Medicine, 1994, 180, S. 2069-2078,

Fugger, L.; Michie, S.A.; Rulifson, I.; Lock, C.B.; Sønderstrup McDevitt, G.: "Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region ß-chain T-cell repertoire and mediates an HLA-DR-restricted immune response," PNAS, 1994, 91, S. 6151-6155,

Kramer, A.; Schneider-Mergener, J.: "Synthesis and application of peptide libraries bound to continuous cellulose membranes," Meth. Mol. Biol., 1998, 87, S. 25-39,

Maier, B.; Molinger, M.; Cope, A.P.; Fugger, L.; Schneider-Mergener, J.; Sønderstrup, G.; Kamradt, T.; Kramer, A.: "Multiple cross-reactive self ligands for Borrelia burgdorferi-specific HLA-DR4-restricted T cells," EJI, 2000, 30, S. 448-457,

Murphy, K.M.; Heimberger, A.B.; Loh, D.Y.: "Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo," Science, 1990, 250, S. 1720-1723,

Klemenz, R.; Hoffmann, S.; Werenskiold, A.K.: "Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen," PNAS, 1989, 86, S. 5708-5712,


40

Tominaga, S.: "A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor," Febs Lett, 1989, 2, 258, S. 301-304,

Kamradt, T.; Lengl-Janßen, B.; Strauss, A.F.; Bansal, G.; Steere, A.C.: "Dominant recognition of a Borrelia burgdorferi outer surface protein A-peptide by T helper cells in patients with treatment-resistant Lyme arthritis," II, 1996, 4, 64, S. 1284-1289,

Germain, R. N.: "MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation," Cell, 1994, 2, 76, S. 287-99,

Tian, J.; Lehmann, P.V.; Kaufmann, D.L.: "T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele," JEM, 1994, 180, S. 1979-1984,

Mason, D.: "A very high level of crossreactivity is an essential feature of the T- cell receptor.," Immunol Today, 1998, 9, 19, S. 395-404,

Kersh, G.J.; Allen, P.M.: "Essential flexibility in the T-cell recognition of antigen," Nature, 1996, 380, S. 495-498,

Wucherpfennig, K.W.; Strominger, J.L.: "Molecular mimicry in T-cell mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein," Cell, 1995, 80, S. 695-705,

Ignatowicz, L.; Kappler, J.; Marrack, P.: "The repertoire of T cells shaped by a single MHC/peptide ligand," Cell, 1996, 4, 84, S. 521-9,

Garboczi, D. N.; Biddison, W. E.: "Shapes of MHC restriction," Immunity, 1999, 1, 10, S. 1-7, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.immunity.com/cgi/content/full/10/1/1

Grogan, J.L.; Kramer, A.; Nogai, A.; Dong, L.; Ohde, M.; Schneider-Mergener, J.; Kamradt, T.: "Crossreactivity of MBP-specific T cells with multiple microbial peptides: EAE-induction in TCR transgenic mice," JI, 1999, 163, S. 3764-3770,

Bjorkman, P.J.; Saper, M.A. ; Samraoui, B.; Bennett, W.S.; J.L., Strominger; Wiley, D.C.: "Structure of the human class I histocompatibility antigen, HLA-A2," Nature, 1987, 329, S. 506-512,

Madden, D. R.; Gorga, J. C.; Strominger, J. L.; Wiley, D. C.: "The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC," Cell, 1992, 6, 70, S. 1035-48,

Brown, J. H.; Jardetzky, T. S.; Gorga, J. C.; Stern, L. J.; Urban, R. G.; Strominger, J. L.; Wiley, D. C.: "Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 [see comments]," Nature, 1993, 6432, 364, S. 33-9,

Falk, K.; Rötzschke, O.; Stevanovïc, S.; Jung, G.; Rammensee, H.G.: "Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules," Nature, 1991, 351, S. 290-296,

Jardetzky, T. S.; Lane, W. S.; Robinson, R. A.; Madden, D. R.; Wiley, D. C.: "Identification of self peptides bound to purified HLA-B27," Nature, 1991, 6342, 353, S. 326-9,


41

Rammensee, H. G.; Friede, T.; Stevanovic, S.: "MHC ligands and peptide motifs: first listing," Immunogenetics, 1995, 4, 41, S. 178-228,

Reay, P. A.; Kantor, R. M.; Davis, M. M.: "Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93-103)," J Immunol, 1994, 8, 152, S. 3946-57,

Hemmer, B.; Vergelli, M.; Pinilla, C.; Houghten, R.; Martin, R.: "Probing degeneracy in T-cell recognition using combinatorial peptide libraries," IT, 1998, 19, S. 163-168,

Hemmer, B.; Vergelli, M.; Gran, B.; Ling, N.; Conlon, P.; Pinilla, C.; Houghton, R.; McFarland, H.F.; Martin, R.: "Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology," JI, 1998, 160, S. 3631-3636,

Ignatowicz, L.; Rees, W.; Pacholczyk, R.; Ignatowicz, H.; Kushnir, E.; Kappler, J.; Marrack, P.: "T cells can be activated by peptides that are unrelated in sequence to their selecting peptide," Immunity, 1997, 2, 7, S. 179-86, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.immunity.com/cgi/content/full/7/2/179

Hemmer, B.; Gran, B.; Zhao, Y.; Marques, A.; Pascal, J.; Tzou, A.; Kondo, T.; Cortese, I.; Bielekova, B.; Straus, S. E.; McFarland, H. F.; Houghten, R.; Simon, R.; Pinilla, C.; Martin, R.: "Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease," Nat Med, 1999, 5, S. 1375-1382,

van Eden, W. ; Holoshitz, J. ; Nevo, Z. ; Frenkel, A.; Klajman, A. ; Cohen, I.R.: "Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans," Proc Natl Acad Sci USA, 1985, 82, S. 5117-5120,

Garza, K. M.; Tung, K. S.: "Frequency of molecular mimicry among T cell peptides as the basis for autoimmune disease and autoantibody induction," J Immunol, 1995, 155, S. 5444-8,

Bachmaier, K.; Neu, N.; de la Maza, L. M.; Pal, S.; Hessel, A.; Penninger, J. M.: "Chlamydia infections and heart disease linked through antigenic mimicry," Science, 1999, 283, S. 1335-1339, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.sciencemag.org/cgi/content/full/283/5406/1335

Singh, V. K.; Yamaki, K.; Donoso, L. A.; Shinohara, T.: "Molecular mimicry. Yeast histone H3-induced experimental autoimmune uveitis," J Immunol, 1989, 5, 142, S. 1512-7,

Horwitz, M.S.; Bradley, L.M.; Harbertson, J.; Krahl, T.; Lee, J.; Sarvetnick, N.: "Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry," Nat Med, 1998, 4, S. 781-785,

Kühn, R.; Lohler, J.; Rennick, D.; Rajewsky, K.; Müller, W.: "Interleukin-10-deficient mice develop chronic enterocolitis," Cell, 1993, 75, S. 263-274,

Green, E. A.; Flavell, R. A.: "The temporal importance of TNFalpha expression in the development of diabetes," Immunity, 2000, 12, S. 459-69, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.immunity.com/cgi/content/full/12/5/459


42

Chabaud, M.; Durand, J. M.; Buchs, N.; Fossiez, F.; Page, G.; Frappart, L.; Miossec, P.: "Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium," Arthritis Rheum, 1999, 5, 42, S. 963-70,

Ziolkowska, M.; Koc, A.; Luszczykiewicz, G.; Ksiezopolska-Pietrzak, K.; Klimczak, E.; Chwalinska-Sadowska, H.; Maslinski, W.: "High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism," J Immunol, 2000, 164, S. 2832-8, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jimmunol.org/v164n5/2832/2832-abs-frame.html

Matusevicius, D.; Kivisakk, P.; He, B.; Kostulas, N.; Ozenci, V.; Fredrikson, S.; Link, H.: "Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis," Mult Scler, 1999, 2, 5, S. 101-4,

Gross, D.M.; Forsthuber, T.; Tary-Lehmann, M.; Etling, C.; Ito, K.; Nagy, Z.A.; Field, J.A.; Steere, A.C.; Huber, B.T.: "Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis," Science, 1998, 281, S. 703-706,

Anderson, A. C.; Nicholson, L. B.; Legge, K. L.; Turchin, V.; Zaghouani, H.; Kuchroo, V. K.: "High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire.," J Exp Med, 2000, 191, S. 761-70, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jem.org/cgi/content/full/191/5/761

Kirberg, J.; Berns, A.; von Boehmer, H.: "Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules," J Exp Med, 1997, 8, 186, S. 1269-75, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jem.org/cgi/content/full/186/8/1269

Witherden, D.; van Oers, N.; Waltzinger, C.; Weiss, A.; Benoist, C.; Mathis, D.: "Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules," J Exp Med, 2000, 191, S. 355-64, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jem.org/cgi/content/full/191/2/355

Kerschensteiner, M.; Gallmeier, E.; Behrens, L.; Leal, V. V.; Misgeld, T.; Klinkert, W. E.; Kolbeck, R.; Hoppe, E.; Oropeza-Wekerle, R. L.; Bartke, I.; Stadelmann, C.; Lassmann, H.; Wekerle, H.; Hohlfeld, R.: "Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation?," J Exp Med, 1999, 189, S. 865-870, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jem.org/cgi/content/full/189/5/865

Ruiz, P. J.; Garren, H.; Hirschberg, D. L.; Langer-Gould, A. M.; Levite, M.; Karpuj, M. V.; Southwood, S.; Sette, A.; Conlon, P.; Steinman, L.: "Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis," JEM, 1999, 189, S. 1275-1284,

Fikrig, E.; Berland, R.; Chen, M.; Williams, S.; Sigal, L. H.; Flavell, R. A.: "Serologic response to the Borrelia burgdorferi flagellin demonstrates an epitope common to a neuroblastoma cell line," Proc Natl Acad Sci U S A, 1993, 1, 90, S. 183-7,

Matsumoto, I.; Staub, A.; Benoist, C.; Mathis, D.: "Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme," Science, 1999, 286, S. 1732-5,

Lambrecht, B. N.; De Veerman, M.; Coyle, A. J.; Gutierrez-Ramos, J. C.; Thielemans, K.; Pauwels, R. A.: "Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation," J Clin Invest, 2000, 106, S. 551-9, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jci.org/cgi/content/full/106/4/551

Tominaga, S.; Yokota, T.; Yanagisawa, K.; Tsukamoto, T.; Takagi, T.; Tetsuka, T.: "Nucleotide sequence of a complementary DNA for human ST2," Biochim Biophys Acta, 1992, 1171, S. 215-218,


43

Xu, D.; Chan, W. L.; Leung, B. P.; Hunter, D.; Schulz, K.; Carter, R. W.; McInnes, I. B.; Robinson, J. H.; Liew, F. Y.: "Selective expression and functions of interleukin 18 receptor on T helper (Th) type 1 but not Th2 cells," J Exp Med, 1998, 188, S. 1485-92, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.jem.org/cgi/content/full/188/8/1485

Mosmann, T.R.; Cherwinski, H.; Bond, M.; Gledlin, M.A.; Coffman, R.L.: "Two types of mouse helper T cell clone. I. Definition according to profile of lymphokine activation and secreted proteins.," JI, 1986, 136, S. 2348-2357,

Heinzel, F.P.; Sadick, M.D.; Holaday, B.J.; Coffman, R.L.; Locksley, R.M.: "Reciprocal expression of interferon-g or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets," JEM, 1989, 169, S. 59-72,

Yamamura, M. ; Uyemura, K. ; Deans, R.J.; Weinberg, K. ; Rea, T.H.; Bloom, B.R.; Modlin, R.L.: "Defining protective responses to pathogens:cytokine profiles in leprosy lesions," Science, 1991, 254, S. 277-279,

Liblau, R.S.; Singer, S.M.; McDevitt, H.O.: "Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases," IT, 1995, 12, S. 34-38,

Donovan, C. E.; Finn, P. W.: "Immune mechanisms of childhood asthma," Thorax, 1999, 54, S. 938-46, http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/referer?http://www.thoraxjnl.com/cgi/content/full/54/10/938

Cheever, A.W.; Finkelman, F.D.; Caspar, P.; Heiny, S.; Macedonia, J.G.; Sher, A.: "Treatment with anti-IL-2 antibodies reduces hepatic pathology and eosinophilia in Schistosoma mansoni-infected mice while selectively inhibiting T cell IL-5 production," JI, 1992, 148, S. 3244-3248,


© Die inhaltliche Zusammenstellung und Aufmachung dieser Publikation sowie die elektronische Verarbeitung sind urheberrechtlich geschützt. Jede Verwertung, die nicht ausdrücklich vom Urheberrechtsgesetz zugelassen ist, bedarf der vorherigen Zustimmung. Das gilt insbesondere für die Vervielfältigung, die Bearbeitung und Einspeicherung und Verarbeitung in elektronische Systeme.

DiML DTD Version 2.0
Zertifizierter Dokumentenserver
der Humboldt-Universität zu Berlin
HTML - Version erstellt am:
Thu Sep 19 16:10:00 2002