| Lein, Michael Torsten : Neue Serummarker bei urologischen Malignomen mit dem Schwerpunkt Prostatakarzinom und Anwendung von Proteinase-Inhibitoren in der Therapie des Prostatakarzinoms |
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E1. Lein M, Jung K, Schnorr D, Henke W, Loening SA: "Strip test for the quick detection of increased concentrations of prostate-specific antigen in blood." Eur J Clin Chem Clin Biochem. 1996; 34: S.511-514.
E2. Lein M, Stephan C, Jung K, Schnorr D, Loening SA: "Relation of free PSA/total PSA in serum for differentiating between patients with prostatic cancer and benign hyperplasia of the prostate: which cutoff should be used" ? Cancer Invest. 1998; 16: S.45-49.
E3. Lein M, Koenig F, Jung K, McGovern FJ, Skates SJ, Schnorr D, Loening SA: "The percentage of free prostate specific antigen is an age-independent tumour marker for prostate cancer: establishment of reference ranges in a large population of healthy men" . Br J Urol. 1998; 82: S.231-236.
E4. Lein M, Brux B, Jung K, Henke W, Koenig F, Stephan C, Schnorr D, Loening SA: "Elimination of serum free and total prostate-specific antigen after radical retropubic prostatectomy" . Eur J Clin Chem Clin Biochem. 1997; 35: S.591-595.
E5. Lein M, Jung K, Brux B, Knäbich A, Sinha P, Schnorr D, Loening SA: "Re: Free and complexed prostate specific antigen in the differentiation of benign prostatic hyperplasia and prostate cancer: studies in serum and plasma samples." J Urol. 1999; 162: S.502-503.
E6. Lein M, Jung K, Elgeti U, Petras T, Stephan C, Brux B, Sinha P, Winkelmann B, Schnorr D, Loening SA: "Comparison of the clinical validity of free-prostate specific antigen, alpha-1-antichymotrypsin-prostate specific antigen and complexed-prostate specific antigen in prostate cancer diagnosis" . Eur Urol , eingereicht. 12/99;
E7. Lein M, Jung K, Hammerer P, Graefen M, Semjonow A, Stieber P, Ossendorf M, Luboldt HJ, Brux B, Stephan C, Schnorr D, Loening SA: "A multicenter clinical trial on the use of alpha-1-antichymotrypsin-prostate-specific antigen in prostate cancer diagnosis." Prostate 2001; 47:
E8. Lein M, Stephan C, Jung K, Schnorr D, Loening SA ": Molekulare Formen des prostataspezifischen Antigens und des humanen Kallikreins 2 als mögliche Indikatoren in der Prostatakarzinomdiagnostik" . Urol A. 2000; 39: S.313-323.
E9. Lein M, Jung K, Weiß S, Schnorr D, Loening SA ": Soluble CD44 variants in serum of patients with urological malignancies." Oncology. 1997; 54: S.226-230.
E10. Lein M, Nowak L, Jung K, Koenig F, Lichtinghagen R, Schnorr D, Loening SA: "Analytical aspects regarding the measurement of metalloproteinases and their inhibitors in blood" . Clin Biochem. 1997; 30: S.491-496.
E11. Lein M, Jung K, Laube Ch, Hübner T, Winkelmann B, Stephan C, Hauptmann S, Rudolph B, Schnorr D, Loening SA ": Matrix-Metalloproteinases and their inhibitors in plasma and tumor tissue of patients with renal cell carcinoma." Int J Cancer . 2000; 85: S.801-804.
E12. Lein M, Nowak L, Jung K, Laube Ch, Ulbricht N, Schnorr D, Loening SA ": Metalloproteinases and tissue inhibitors of matrix-metalloproteinases in plasma of patients with prostate cancer and in prostate cancer tissue. " Ann NY Acad Sci. 1999; 878: S.544-546.
E13. Lein M, Koenig F, Misdraji J, McDougal WS, Jung K, Loening SA, Hasan T, Ortel B ": Laser-induced hyperthermia in rat prostate cancer: role of site of tumor implantation." Urology. 2000; 56: S.167-172.
E14. Lein M, Jung K, Le DK, Hasan T, Ortel B, Borchert D, Winkelmann B, Schnorr D, Loening SA: "Synthetic inhibitor of matrix metalloproteinases (Batimastat) reduces the prostate cancer growth in an orthotopic rat model" . Prostate. 2000; 43: S.77-82.
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K1. Jung K, Zachow J, Lein M, Brux B, et al ".: Rapid detection of elevated prostate-specific antigen levels in blood: performance of various membrane strip test compared." Urology . 1999; 53: S.155-160.
K2. Stephan C, Lein M, Jung J, Schnorr D, et al ".: The influence of prostate volume on the ratio of free to total prostate specific antigen in serum of patients with prostate carcinoma and benign prostate hyperplasia. " Cancer. 1997; 79: S.104-109.
K3. Jung K, Meyer A, Lein M, Rudolph B, et al ".: Ratio of free to total prostate specific antigen in serum can not distinguish patients with prostate cancer from those with chronic inflammation of the prostate." J Urol. 1998; 159: S.1595-1598.
K4. Meyer A, Jung K, Lein M, Schnorr D, et al ".: Factors influencing the ratio of free to total prostate specific antigen in serum." Int J Cancer. 1997; 74: S.630-636.
K5. Stephan C, Jung K, Brux B, Lein M, et al ".: ACT-PSA and complexed PSA elimination kinetics in serum after radical retropubic prostatectomy: proof of new complex forming of PSA after release into circulation. " Urology. 2000; 55: S.560-563.
K6. Jung K, Brux B, Lein M, Knäbich A, et al ".: Determination of alpha1-antichymotrypsin-PSA complex in serum does not improve the differentiation between benign prostatic hyperplasia and prostate cancer compared with total PSA and percent free PSA." Urology. 1999; 53: S.1160-1168.
K7. Jung K, Elgeti U, Lein M, Brux B, et al ".: Ratio of free or complexed prostate-specific antigen (PSA) to total PSA: which ratio improves differentiation between benign prostatic hyperplasia and prostate cancer?. " Clin Chem . 2000; 46: S.55-62.
K8. Jung K, Lein M, Weiss S, Schnorr D, et al.: " Soluble CD44 molecules in serum of patients with prostate cancer and benign prostatic hyperplasia. " Eur J Cancer. 1996; 32: S.627-630.
K9. Lein M, Weiss S, Jung K, Schnorr D, et al ".: Soluble CD44 variants in serum of patients with prostate cancer and other urological malignancies." Prostate. 1996; 29: S.334-335.
K10. Lein M, Jung K, Nowak L, Schnorr D, et al ".: Analytical aspects regarding the measurement of metalloproteinases. " Ann NY Acad Sci. 1999; 878: S.491-493.
K11. Jung K, Laube C, Lein M, Lichtinghagen R, et al ".: Kind of sample as preanalytical determinant of matrix metalloproteinases 2 and 9 and tissue inhibitor of metalloproteinase 2 in blood." Clin Chem. 1998; 44: S.1060-1062.
K12. Jung K, Nowak L, Lein M, Henke W, et al.: " What kind of specimen should be selected for determining tissue inhibitor of metalloproteinase-1 (TIMP-1) in blood? " Clin Chim Acta. 1996. 254; 97-100.:
K13. Jung K, Nowak L, Lein M, Priem F, et al ".: Matrix metalloproteinases 1 and 3, tissue inhibitor of metalloproteinase 1 and the complex of metalloproteinase 1/tissue inhibitor in plasma of patients with prostate cancer. " Int J Cancer (Pred Oncol). 1997; 74: S.220-223.
K14. Jung K, Lein M, Ulbrich N, Rudolph B, et al ".: Quantification of matrix metalloproteinases and tissue inhibitors of metalloproteinase in prostatic tissue: analytical aspects" . Prostate. 1998; 34: S.130-136.
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