[Seite 27↓]


[1] (1998): Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee, Lancet 351 [9111], pp.1225-32..

[2] Arshad, S. H.; Tariq, S. M.; Matthews, S. and Hakim, E. (2001): Sensitization to common allergens and its association with allergic disorders at age 4 years: a whole population birth cohort study, Pediatrics 108 [2], p.E33..

[3] Croner, S. and Kjellman, N. I. (1992): Natural history of bronchial asthma in childhood. A prospective study from birth up to 12-14 years of age, Allergy 47 [2 Pt 2], pp.150-7..

[4] Ownby, D. R.; Peterson, E. L. and Johnson, C. C. (2000): Factors related to methacholine airway responsiveness in children, Am J Respir Crit Care Med 161 [5], pp.1578-83..

[5] Palmer, L. J.; Rye, P. J.; Gibson, N. A.; Burton, P. R.; Landau, L. I. and Lesouef, P. N. (2001): Airway responsiveness in early infancy predicts asthma, lung function, and respiratory symptoms by school age, Am J Respir Crit Care Med 163 [1], pp.37-42..

[6] Rhodes, H. L.; Sporik, R.; Thomas, P.; Holgate, S. T. and Cogswell, J. J. (2001): Early life risk factors for adult asthma: a birth cohort study of subjects at risk, J Allergy Clin Immunol 108 [5], pp.720-5.. http://www.mosby.com/scripts/om.dll/serve?action=searchDB&searchDBfor=art&artType=abs&id=a119151&target=

[7] Tariq, S. M.; Matthews, S. M.; Hakim, E. A.; Stevens, M.; Arshad, S. H. and Hide, D. W. (1998): The prevalence of and risk factors for atopy in early childhood: a whole population birth cohort study, J Allergy Clin Immunol 101 [5], pp.587-93..

[8] Kulig, M.; Bergmann, R.; Klettke, U.; Wahn, V.; Tacke, U. and Wahn, U. (1999): Natural course of sensitization to food and inhalant allergens during the first 6 years of life, J Allergy Clin Immunol 103 [6], pp.1173-9..

[9] Togias, A. (1999): Mechanisms of nose-lung interaction, Allergy 54 [Suppl 57], pp.94-105..

[10] Gereda, J. E.; Leung, D. Y.; Thatayatikom, A.; Streib, J. E.; Price, M. R.; Klinnert, M. D. and Liu, A. H. (2000): Relation between house-dust endotoxin exposure, type 1 T-cell development, and allergen sensitisation in infants at high risk of asthma, Lancet 355 [9216], pp.1680-3..

[11] Illi, S.; von Mutius, E.; Lau, S.; Bergmann, R.; Niggemann, B.; Sommerfeld, C. and Wahn, U. (2001): Early childhood infectious diseases and the development of asthma up to school age: a birth cohort study, Bmj 322 [7283], pp.390-5..

[12] Von Ehrenstein, O. S.; Von Mutius, E.; Illi, S.; Baumann, L.; Bohm, O. and von Kries, R. (2000): Reduced risk of hay fever and asthma among children of farmers, Clin Exp Allergy 30 [2], pp.187-93..

[13] von Mutius, E.; Martinez, F. D.; Fritzsch, C.; Nicolai, T.; Reitmeir, P. and Thiemann, H. H. (1994): Skin test reactivity and number of siblings, Bmj 308 [6930], pp.692-5..

[14] von Mutius, E.; Martinez, F. D.; Fritzsch, C.; Nicolai, T.; Roell, G. and Thiemann, H. H. (1994): Prevalence of asthma and atopy in two areas of West and East Germany, Am J Respir Crit Care Med 149 [2 Pt 1], pp.358-64..

[15] von Mutius, E.; Braun-Fahrlander, C.; Schierl, R.; Riedler, J.; Ehlermann, S.; Maisch, S.; Waser, M. and Nowak, D. (2000): Exposure to endotoxin or other bacterial components might protect against the development of atopy, Clin Exp Allergy 30 [9], pp.1230-4..

[16] Sandford, A.; Weir, T. and Pare, P. (1996): The genetics of asthma, Am J Respir Crit Care Med 153 [6 Pt 1], pp.1749-65..

[17] Skadhauge, L. R.; Christensen, K.; Kyvik, K. O. and Sigsgaard, T. (1999): Genetic and environmental influence on asthma: a population-based study of 11,688 Danish twin pairs, Eur Respir J 13 [1], pp.8-14..

[18] Lander, E. S. and Schork, N. J. (1994): Genetic dissection of complex traits, Science 265 [5181], pp.2037-48..

[19] Sengler, C.; Lau, S.; Wahn, U. and Nickel, R. (2002): Interactions between genes and environmental factors in asthma and atopy: new developments, Respir Res 3 [1], p.7..

[20] Van Eerdewegh, P.; Little, R. D.; Dupuis, J.; Del Mastro, R. G.; Falls, K.; Simon, J.; Torrey, D.; Pandit, S.; McKenny, J.; Braunschweiger, K.; Walsh, A.; Liu, Z.; Hayward, B.; Folz, C.; Manning, S. P.; Bawa, A.; Saracino, L.; Thackston, M.; Benchekroun, Y.; Capparell, N.; Wang, M.; Adair, R.; Feng, Y.; Dubois, J.; FitzGerald, M. G.; Huang, H.; Gibson, R.; Allen, K. M.; Pedan, A.; Danzig, M. R.; Umland, S. P.; Egan, R. W.; Cuss, F. M.; Rorke, S.; Clough, J. B.; Holloway, J. W.; Holgate, S. T. and Keith, T. P. (2002): Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness, Nature 418 [6896], pp.426-30..

[21] Heinzmann, A.; Mao, X. Q.; Akaiwa, M.; Kreomer, R. T.; Gao, P. S.; Ohshima, K.; Umeshita, R.; Abe, Y.; Braun, S.; Yamashita, T.; Roberts, M. H.; Sugimoto, R.; Arima, K.; Arinobu, Y.; Yu, B.; Kruse, S.; Enomoto, T.; Dake, Y.; Kawai, M.; Shimazu, S.; Sasaki, S.; Adra, C. N.; Kitaichi, M.; Inoue, H.; Yamauchi, K.; Tomichi, N.; Kurimoto, F.; Hamasaki, N.; Hopkin, J. M.; Izuhara, K.; Shirakawa, T. and Deichmann, K. A. (2000): Genetic variants of IL-13 signalling and human asthma and atopy, Hum Mol Genet 9 [4], pp.549-59..

[22] Liu, X.; Nickel, R.; Beyer, K.; Wahn, U.; Ehrlich, E.; Freidhoff, L. R.; Bjorksten, B.; Beaty, T. H. and Huang, S. K. (2000): An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German multicenter atopy study (MAS-90), J Allergy Clin Immunol 106 [1 Pt 1], pp.167-70..

[23] Graves, P. E.; Kabesch, M.; Halonen, M.; Holberg, C. J.; Baldini, M.; Fritzsch, C.; Weiland, S. K.; Erickson, R. P.; von Mutius, E. and Martinez, F. D. (2000): A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children, J Allergy Clin Immunol 105 [3], pp.506-13..

[24] Hershey, G. K.; Friedrich, M. F.; Esswein, L. A.; Thomas, M. L. and Chatila, T. A. (1997): The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor, N Engl J Med 337 [24], pp.1720-5..

[25] Baldini, M.; Lohman, I. C.; Halonen, M.; Erickson, R. P.; Holt, P. G. and Martinez, F. D. (1999): A Polymorphism* in the 5' flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E, Am J Respir Cell Mol Biol 20 [5], pp.976-83..

[26] Koppelman, G. H.; Reijmerink, N. E.; Colin Stine, O.; Howard, T. D.; Whittaker, P. A.; Meyers, D. A.; Postma, D. S. and Bleecker, E. R. (2001): Association of a promoter polymorphism of the CD14 gene and atopy, Am J Respir Crit Care Med 163 [4], pp.965-9..

[27] Laing, I. A.; Goldblatt, J.; Eber, E.; Hayden, C. M.; Rye, P. J.; Gibson, N. A.; Palmer, L. J.; Burton, P. R. and Le Souef, P. N. (1998): A polymorphism of the CC16 gene is associated with an increased risk of asthma, J Med Genet 35 [6], pp.463-7..

[28] Laing, I. A.; Hermans, C.; Bernard, A.; Burton, P. R.; Goldblatt, J. and Le Souef, P. N. (2000): Association between plasma CC16 levels, the A38G polymorphism, and asthma, Am J Respir Crit Care Med 161 [1], pp.124-7..

[29] Spiteri, M. A.; Bianco, A.; Strange, R. C. and Fryer, A. A. (2000): Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation, Allergy 55 Suppl 61 [8], pp.15-20..

[30] Becker, K. G.; Simon, R. M.; Bailey-Wilson, J. E.; Freidlin, B.; Biddison, W. E.; McFarland, H. F. and Trent, J. M. (1998): Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases, Proc Natl Acad Sci U S A 95 [17], pp.9979-84.. http://www.pnas.org/cgi/content/full/95/17/9979

[31] Lee, Y. A.; Wahn, U.; Kehrt, R.; Tarani, L.; Businco, L.; Gustafsson, D.; Andersson, F.; Oranje, A. P.; Wolkertstorfer, A.; Berg, Av; Hoffmann, U.; Kuster, W.; Wienker, T.; Ruschendorf, F. and Reis, A. (2000): A major susceptibility locus for atopic dermatitis maps to chromosome 3q21, Nat Genet 26 [4], pp.470-3..

[32] Cookson, W. O.; Ubhi, B.; Lawrence, R.; Abecasis, G. R.; Walley, A. J.; Cox, H. E.; Coleman, R.; Leaves, N. I.; Trembath, R. C.; Moffatt, M. F. and Harper, J. I. (2001): Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci, Nat Genet 27 [4], pp.372-3..

[33] Nickel, R.; Niggemann, B.; Gruber, C.; Kulig, M.; Wahn, U. and Lau, S. (2002): How should a birth cohort study be organised? Experience from the German MAS cohort study, Paediatr Respir Rev 3 [3], pp.169-76..

[34] Warner, J. O. (2001): A double-blinded, randomized, placebo-controlled trial of cetirizine in preventing the onset of asthma in children with atopic dermatitis: 18 months' treatment and 18 months' posttreatment follow-up, J Allergy Clin Immunol 108 [6], pp.929-37..

[35] Barnes, K. C.; Neely, J. D.; Duffy, D. L.; Freidhoff, L. R.; Breazeale, D. R.; Schou, C.; Naidu, R. P.; Levett, P. N.; Renault, B.; Kucherlapati, R.; Iozzino, S.; Ehrlich, E.; Beaty, T. H. and Marsh, D. G. (1996): Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: evidence from Afro-Caribbean and Caucasian populations, Genomics 37 [1], pp.41-50..

[36] Nickel, R.; Wahn, U.; Hizawa, N.; Maestri, N.; Duffy, D. L.; Barnes, K. C.; Beyer, K.; Forster, J.; Bergmann, R.; Zepp, F.; Wahn, V. and Marsh, D. G. (1997): Evidence for linkage of chromosome 12q15-q24.1 markers to high total serum IgE concentrations in children of the German Multicenter Allergy Study, Genomics 46 [1], pp.159-62..

[37] Nickel, R.; Kulig, M.; Forster, J.; Bergmann, R.; Bauer, C. P.; Lau, S.; Guggenmoos-Holzmann, I. and Wahn, U. (1997): Sensitization to hen's egg at the age of twelve months is predictive for allergic sensitization to common indoor and outdoor allergens at the age of three years, J Allergy Clin Immunol 99 [5], pp.613-7..

[38] Illi, S.; Von Mutius, E.; Lau, S.; Nickel, R.; Niggemann, B.; Sommerfeld, C. and Wahn, U. (2001): The pattern of atopic sensitization is associated with the development of asthma in childhood, J Allergy Clin Immunol 108 [5 Part 1], pp.709-14.. http://www.mosby.com/scripts/om.dll/serve?action=searchDB&searchDBfor=art&artType=abs&id=a118786&target=

[39] Gruber, C.; Illi, S.; Lau, S.; Nickel, R.; Forster, J.; Kamin, W.; Bauer, C. P.; Wahn, V. and Wahn, U. (2003): Transient suppression of atopy in early childhood is associated with high vaccination coverage, Pediatrics 111 [3], pp.e282-8..

[40] Alm, J. S.; Swartz, J.; Lilja, G.; Scheynius, A. and Pershagen, G. (1999): Atopy in children of families with an anthroposophic lifestyle, Lancet 353 [9163], pp.1485-8..

[41] Nickel, R.; Lau, S.; Niggemann, B.; Sommerfeld, C. and Wahn, U. (2002): Comparison of bronchial responsiveness to histamine in asthma, allergic rhinitis and allergic sensitization at the age of 7 years, Clin Exp Allergy 32 [9], pp.1274-7..

[42] Beyer, K.; Nickel, R.; Freidhoff, L.; Bjorksten, B.; Huang, S. K.; Barnes, K. C.; MacDonald, S.; Forster, J.; Zepp, F.; Wahn, V.; Beaty, T. H.; Marsh, D. G. and Wahn, U. (2000): Communications: association and linkage of atopic dermatitis with chromosome 13q12-14 and 5q31-33 markers, J Invest Dermatol 115 [5], pp.906-8..

[43] Liu, X.; Beaty, T. H.; Deindl, P.; Huang, S. K.; Lau, S.; Sommerfeld, C.; Fallin, M. D.; Kao, W. H.; Wahn, U. and Nickel, R. (2003): Associations between total serum IgE levels and the 6 potentially functional variants within the genes IL4, IL13, and IL4RA in German children: the German Multicenter Atopy Study, J Allergy Clin Immunol 112 [2], pp.382-8..

[44] Sengler, C.; Heinzmann, A.; Jerkic, S. P.; Haider, A.; Sommerfeld, C.; Niggemann, B.; Lau, S.; Forster, J.; Schuster, A.; Kamin, W.; Bauer, C.; Laing, I.; LeSouef, P.; Wahn, U.; Deichmann, K.; Nickel, R.; Baldini, M. and Martinez, F. (2003): Clara cell protein 16 (CC16) gene polymorphism influences the degree of airway responsiveness in asthmatic children, J Allergy Clin Immunol 111 [3], pp.515-9..

[45] Drysdale, C. M.; McGraw, D. W.; Stack, C. B.; Stephens, J. C.; Judson, R. S.; Nandabalan, K.; Arnold, K.; Ruano, G. and Liggett, S. B. (2000): Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness, Proc Natl Acad Sci U S A 97 [19], pp.10483-8..

[46] Nickel, R. G.; Casolaro, V.; Wahn, U.; Beyer, K.; Barnes, K. C.; Plunkett, B. S.; Freidhoff, L. R.; Sengler, C.; Plitt, J. R.; Schleimer, R. P.; Caraballo, L.; Naidu, R. P.; Levett, P. N.; Beaty, T. H. and Huang, S. K. (2000): Atopic dermatitis is associated with a functional mutation in the promoter of the C-C chemokine RANTES, J Immunol 164 [3], pp.1612-6..

[47] Le Souef, P. N.; Goldblatt, J. and Lynch, N. R. (2000): Evolutionary adaptation of inflammatory immune responses in human beings, Lancet 356 [9225], pp.242-4..

[48] Marquet, S.; Abel, L.; Hillaire, D.; Dessein, H.; Kalil, J.; Feingold, J.; Weissenbach, J. and Dessein, A. J. (1996): Genetic localization of a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31-q33, Nat Genet 14 [2], pp.181-4..

[49] Rihet, P.; Traore, Y.; Abel, L.; Aucan, C.; Traore-Leroux, T. and Fumoux, F. (1998): Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33, Am J Hum Genet 63 [2], pp.498-505.. http://www.journals.uchicago.edu/cgi-bin/resolve?AJHG980143ABS

[50] Ramsay, C. E.; Hayden, C. M.; Tiller, K. J.; Burton, P. R.; Hagel, I.; Palenque, M.; Lynch, N. R.; Goldblatt, J. and LeSouef, P. N. (1999): Association of polymorphisms in the beta2-adrenoreceptor gene with higher levels of parasitic infection, Hum Genet 104 [3], pp.269-74..

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