]> Interaktion von Retinolsäurerezeptoren und Androgenrezeptor bei Androgen- und Retinoid- Stimulation von Prostatazellen und Prostatakarzinomzellen<BR>- möglicher Ansatz zur Therapie des Prostatakarzinoms HABILITATIONSSCHRIFT Zur Erlangung des akademischen Grades
Dr. med. habil.
(doctor medicinae habilitatus)
vorgelegt von
Dr. med. Frank Richter
aus Magdeburg
Präsident: Prof. Dr. rer. nat J.Mlynek
Dekan: Prof. Dr. Joachim W. Dudenhausen
Eingereicht im September 2001 2

Die Ergebnisse der vorliegenden Habilitationsschrift wurden in folgenden Abstracts und Publikationen veröffentlicht (chronologisch geordnet):

  1. F.Richter: ”Influence of retinoic acid on cell proliferation of NRP152 and NRP154 -a cancerogenous and a non-cancerogenous cell line from rat prostate.” Abstract.
    Summer Research Conference ”Advances in Cell Biology” of the American Urological Association (AUA), 9.-11. August 1996, Houston, Texas, USA.
  2. M.T. Li, F. Richter, H.F.S. Huang, R. J. Irwin:
    ”Interaction of testosterone and retinoic acid on human prostate cancer cells.” Abstract.
    37th Annual Meeting of theAmerican Society for Cell Biology,13.-17. Dezember 1997; Washington DC, USA.
  3. F. Richter, H.F.S. Huang, M.T. Li, D. Danielpour, R.J. Irwin:
    ” Tumorigenesis of rat prostate epithelial cells is associated with an altered retinoic acid / RAR- pathway.” Abstract. International Symposium on Biology of Prostate Growth.15.-18. März 1998. NIH, Bethesda, Maryland,USA
  4. F. Richter, H. F.S. Huang, M.T. Li, R. Irwin:
    ”Expression von Retinolsäuerezeptor (RAR)mRNA in humanem Prostatakarzinom und Prostatagewebe.”Abstract. Jahrestagung der ”Deutschen Gesellschaft für Urologie”
    Hamburg, 23. - 26. September 1998.
  5. F. Richter:” Differences in expression of retinoic acid receptor mRNAs in human prostate versus prostate cancer.”Abstract. Foundation of the Clinical Research Center and
    Institute for Biomedical Research,Hackensack University Medical Center,
    Hackensack, New Jersey, USA, 13. November 1998.
  6. F. Richter, H.F.S. Huang, M.T. Li, D. Danielpour, R.J. Irwin:
    ”Tumorigenesis of rat prostate epithelial cells is associated with an altered retinoic acid / RAR- pathway.”Prostate 38:4; 340-341, 1999.
  7. F. Richter, H.F.S. Huang, M.T. Li, R.J. Irwin Jr:
    ”Retinoid and androgen regulation of cell growth; Epidermal Growth Factor and Retinoic Acid Receptors in normal and carcinoma rat prostate cells.”
    Molecular and Cellular Endocrinology 153: 29-38, 1999.
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  9. F. Richter, D. O`Keefe, D.J. Bacich, A. Uchida, M. Bisogna , W.D.W. Heston:
    ”Co-incubation of microvascular endothelial cells with breast cancer cell line stimulates PSMA-expression in vitro.” Poster, Annual Meeting of the American Association for Cancer Research (AACR), San Francisco, 5. April, 2000.
    Proceedings of the American Association for Cancer Resarch 41: 794 ; 2000 (Abstract 5051).
  10. F. Richter, D. O`Keefe, D.J. Bacich, A. Uchida, M. Bisogna , W.D.W. Heston:
    ”Co-incubation of microvascular endothelial cells with breast cancer cell line stimulates PSMA-expression in vitro.”Abstract, 95th Annual Meeting of the American Urological Association (AUA), Atlanta, USA, 30. April, 2000.
  11. Li, M.-T., Richter, F., Hsiao, P.-W., Wang, C, Chang, C., Irwin, R.J., Huang, H.F.S.:
    ” Androgen and retinoic acid interaction in LNCaP cells. Effects on cell proliferation and expression of retinoic acid receptor and epidermal growth factor receptor. (Molecular and Cellular Endocrinology (in Revision).
  12. Li, M.-T., Richter, F., Hsiao, P.-W., Wang, C,., Irwin, R.J., Huang, H.F.S.:
    ”Differential Expression of Retinoid acid receptors in the Rat Prostate - Effect of Anatomic Location and Castration.” (Endocrinology, eingereicht 1/2001).
  13. Richter F., Joyce, A. , Fromowitz, F, Irwin, R.J.,Huang, H.F.S.:
    Expression of Retinoid Acid Receptors in Human Prostate and Prostate Cancer.
    Journal of Cellular Endocrinology and Metabolism (eingereicht 4/2001).

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