Steinhoff, Ulrich Johannes: Von Toleranz zur Autoimmunität. In vivo Analysen über die Funktion und die Bedeutung autoreaktiver CD4+ und CD8+ T-Zellen

32

7 Literaturverzeichnis

7.1 Eigenzitate

(1) Steinhoff, U., C. Burkhardt, H. Hengartner and R. Zinkernagel (1993) . "Virus and hapten-carrier complexes can activate autoreactive B cells by providing linked T help" . Eur. J. Immunol ., 24 :773-776

(2) Ulrich Steinhoff . "Analysis of the antibody response against Vesicular Stomatitis Virus (VSV) and Lymphocytic Choriomenigitis Virus (LCMV)" . In: Immunology Methods Manual , Academic Press (1997)

(3) Bachmann, M.F., U. Hoffmann Rohrer, U. Steinhoff, K. Bürki, S. Skuntz, H. Arnheiter, H. Hengartner and R. M. Zinkernagel (1994) . "T helper unresponsiveness: rapid induction in antigen transgenic and reversion in non-transgenic mice" . Eur. J. Immunol ., 24 :2966-2973

(4) Steinhoff, U., K.J. Maloy, C. Burkhart, A.J. Clark, T. Rülicke, H. Hengartner and R.M. Zinkernagel (1999). "Variable Immune response against a developmentally regulated self-antigen." J. Autoimmun ., 12 : 27-34

(5) Kaufmann, S.H.E., B. Schoel, J.D.A. v. Embden, T. Koga, A Wand-Württenberger, M.E. Munk and U. Steinhoff (1991) . "Heat-shock protein 60: implication for pathogenesis of and protection against bacterial infections." Immunol. Reviews 121 :67-90

(6) Steinhoff, U., U. Zügel, H.Hengel, R. Rösch, M.E. Munk and S.H.E. Kaufmann (1994) . "Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by anti-sense oligonucleotide treatment" . Proc. Natl. Acad. Sci., USA 91 :5085-5088

(7) Steinhoff, U., V. Brinkmann, U. Klemm, P. Aichele, P. Seiler, I. Prinz, U. Zügel and S.H.E. Kaufmann (1999) . "Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells." Immunity 11: 349-358

(8) Kuckelkorn, U., T.Ruppert, P.Jungblut, U. Zimny-Arndt, S.Lamers, I.Prinz, I. Drung, P-M. Kloetzel, S.H.E. Kaufmann and U. Steinhoff (2002) . "A link between autoimmunity and organ-specific antigen processing by 20S proteasomes." J.Exp. Med. 195: 983-990


33

(9) Prinz, I., J. Zerrhan, S.H.E. Kaufmann and U. Steinhoff. " Promiscous peptide recognition of an autoreactive CD8 T cell clone is responsible for autoimmune intestinal pathology. " J. Autoimmun "." 18 ":" 281-287 " "

7.2 Fremdzitate

1. Black, P. ( 2001). "Why is the prevalence of allergy and autoimmunity increasing?" Trends Immunol. 22 : 354-355.

2. Benoist, C. and D.Mathis ( 2001). "Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry?" Nat.Immunol. 2: 797-801.

3. Kappler, J.W., N.Roehm, and P.Marrack ( 1987). "T cell tolerance by clonal elimination in the thymus." Cell 49: 273-280 .

4 . Bluthmann, H., P.Kisielow, Y.Uematsu, M.Malissen, P.Krimpenfort, A.Berns, H.von Boehmer, and M.Steinmetz (1988) ". T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous alpha- and beta-genes. " Nature 334: 156-159.

5. Zal, T., A.Volkmann, and B.Stockinger (1994). " Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen." J.Exp.Med. 180: 2089-2099.

6. Klein, L. and B.Kyewski (2000). " "Promiscuous" expression of tissue antigens in the thymus: a key to T-cell tolerance and autoimmunity? " J.Mol.Med. 78: 483-494.

7. Ohashi, P.S., S.Oehen, K.Buerki, H.Pircher, C.T.Ohashi, B.Odermatt, B.Malissen, R.M.Zinkernagel, and H.Hengartner (1991). "Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice." Cell 65: 305-317.

8. Webb,S., C.Morris, and J.Sprent (1990). "Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. " Cell 63: 1249-1256.

9. Rocha, B. and H.von Boehmer (1991). "Peripheral selection of the T cell repertoire." Science 251: 1225-1228.

10. Forster, I. (1998). "Controlling autoreactivity of CD4 T cells by local tolerance induction. " Dev.Immunol. 6: 89-94.

11. Bevan, M.J. (1976). "Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay." J.Exp.Med. 143: 1283-1288.

12. Miller, J.F., C.Kurts, J.Allison, H.Kosaka, F.Carbone, and W.R.Heath (1998). "Induction of peripheral CD8+ T-cell tolerance by cross-presentation of self "


34

"antigens. " Immunol.Rev. 165: 267-277.

13. Miller, J.F. and W.R.Heath (1993). "Self-ignorance in the peripheral T-cell pool." Immunol.Rev. 133: 131-150.

14. Oldstone, M.B., M.Nerenberg, P.Southern, J.Price, and H.Lewicki (1991). "Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response." Cell 65: 319-331.

15. Bretscher, P.A. (1975). "The two signal model for B cell induction. " Transplant.Rev. 23: 37-48.

16. Bretscher, P. (1992). "The two-signal model of lymphocyte activation twenty-one years later." Immunol.Today 13: 74-76.

17. Schwartz, R.H. (1996) . "Models of T cell anergy: is there a common molecular mechanism? " J.Exp.Med. 184: 1-8.

18. Bell, D., J.W.Young, and J.Banchereau (1999) . "Dendritic cells." Adv.Immunol. 72: 255-324.

19. Moskophidis, D., F.Lechner, H.Pircher, and R.M.Zinkernagel (1993). "Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells." Nature 362: 758-761.

20. Ehl, S., P.Aichele, H.Ramseier, W.Barchet, J.Hombach, H.Pircher, H.Hengartner, and R.M.Zinkernagel (1998). "Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection." Nat.Med. 4: 1015-1019.

21. Saoudi, A., B.Seddon, D.Fowell, and D.Mason (1996). "The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients." J.Exp.Med. 184: 2393-2398.

22. Fowell, D. and D.Mason (1993). "Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential." J.Exp.Med. 177: 627-636.

23. Read, S., V.Malmstrom, and F.Powrie (2000). "Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation." J.Exp.Med. 192: 295-302.

24. Martin, J. and F.U.Hartl (1997). "Chaperone-assisted protein folding." Curr.Opin.Struct.Biol. 7: 41-52.

25. Williams, D.B. and T.H.Watts (1995). "Molecular chaperones in antigen presentation." Curr.Opin.Immunol. 7: 77-84.

26. Kol,A., A.H.Lichtman, R.W.Finberg, P.Libby, and E.A.Kurt-Jones (2000). "Cutting "


35

"edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells." J.Immunol. 164: 13-17.

27. Zügel, U. and S.H.Kaufmann (1999). "Role of heat shock proteins in protection from and pathogenesis of infectious diseases." Clin.Microbiol.Rev. 12: 19-39.

28. Cohen, I.R. (1991). "Autoimmunity to chaperonins in the pathogenesis of arthritis and diabetes. " Annu.Rev.Immunol. 9: 567-589.

29. Elias, D., D.Markovits, T.Reshef, Z.R.van der, and I.R.Cohen (1990). "Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein. " Proc.Natl.Acad.Sci.U.S.A 87: 1576-1580.

30. van Eden, W., J.E.Thole, Z.R.van der, A.Noordzij, J.D.van Embden, E.J.Hensen, and I.R.Cohen (1988). "Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis" . Nature 331: 171-173.

31. Elias, D. and I.R.Cohen (1994). "Peptide therapy for diabetes in NOD mice. " Lancet 343: 704-706.

32. Yang, X.D., J.Gasser, and U.Feige (1992). "Prevention of adjuvant arthritis in rats by a nonapeptide from the 65-kD mycobacterial heat shock protein: specificity and mechanism." Clin.Exp.Immunol. 87: 99-104.

33. Yewdell, J.W. and J.R.Bennink (1999). "Mechanisms of viral interference with MHC class I antigen processing and presentation." Annu.Rev.Cell Dev.Biol. 15: 579-606.

34. Craiu, A., T.Akopian, A.Goldberg, and K.L.Rock (1997). "Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide." Proc Natl Acad Sci U S A 94: 10850-10855.

35. Stoltze, L., M.Schirle, G.Schwarz, C.Schroter, M.W.Thompson, L.B.Hersh, H.Kalbacher, S.Stevanovic, H.G.Rammensee, and H. Schild (2001). "Two new proteases in the MHC class I processing pathway." Nature Immunology 1: 413-418.

36. Groll, M., L.Ditzel, J.Lowe, D.Stock, M.Bochtler, H.D.Bartunik, and R.Huber (1997). " Structure of 20S proteasome from yeast at 2.4 A resolution." Nature 386: 463-471.

37. Morel, S., F.Levy, O.Burlet-Schiltz, F.Brasseur, M.Probst-Kepper, A.L.Peitrequin, B.Monsarrat, R.Van Velthoven, J.C.Cerottini, T.Boon, J.E.Gairin, and B.J.Van den Eynde (2000). "Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells." Immunity 12: 107-117.

38. Burkhart, C., G.Freer, U.Steinhoff, Y.Li, D.H.Bishop, R.M.Zinkernagel, and H.Hengartner (1994). "Localization of T helper cell epitopes in the vesicular stomatitis virus: the nucleoprotein is responsible for serotype cross-reactive T "


36

"help." Viral Immunol 7: 103-111.

39. Young, R.A. (1990). "Stress proteins and immunology" . Annu.Rev.Immunol. 8: 401-420.

40. Nemazee, D.A. and K.Burki (1989). "Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes" . Nature 337: 562-566.

41. Adelstein, S., H.Pritchard-Briscoe, T.A.Anderson, J.Crosbie, G.Gammon, R.H.Loblay, A.Basten, and C.C.Goodnow (1991). "Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen." Science 251: 1223-1225.

42. Zinkernagel, R.M. and H.Hengartner (2001). "Regulation of the immune response by antigen." Science 293: 251-253.

43. McMurray, R.W. (2001). "Estrogen, prolactin, and autoimmunity: actions and interactions." Int. Immunopharmacol. 1: 995-1008.

44. Ito, A., B.F.Bebo, Jr., A.Matejuk, A.Zamora, M.Silverman, A.Fyfe-Johnson, and H.Offner (2001). "Estrogen treatment down-regulates TNF-alpha production and reduces the severity of experimental autoimmune encephalomyelitis in cytokine knockout mice. " J.Immunol. 167: 542-552.

45. Kousta, E., N.J.Lawrence, V.Anyaoku, D.G.Johnston, and M.I.McCarthy (2001). "Prevalence and features of pancreatic islet cell autoimmunity in women with gestational diabetes from different ethnic groups." BJOG . 108: 716-720.

46. Muller, A.F., H.A.Drexhage, and A.Berghout (2001). "Postpartum thyroiditis and autoimmune thyroiditis in women of childbearing age: recent insights and consequences for antenatal and postnatal care." Endocr.Rev. 22: 605-630.

47. Akkaraju, S., W.Y.Ho, D.Leong, K.Canaan, M.M.Davis, and C.C.Goodnow (1997). "A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis. " Immunity . 7: 255-271.

48 . Powrie, F . (1995). "T cells in inflammatory bowel disease: protective and pathogenic roles." Immunity. 3: 171-174.

49. Rose, N.R . (1998). "The role of infection in the pathogenesis of autoimmune disease." Semin.Immunol. 10: 5-13.

50. Kisielow, P. and H.von Boehmer (1995). "Development and selection of T cells: facts and puzzles." Adv. Immunol. 58: 87-209.

51. Takeda, S., H.R.Rodewald, H.Arakawa, H.Bluethmann, and T.Shimizu (1996). "MHC class II molecules are not required for survival of newly generated CD4+ T "


37

"cells, but affect their long-term life span." Immunity . 5: 217-228.

52. Kirberg, J., H.von Boehmer, T.Brocker, H.R.Rodewald, and S.Takeda (2001). "Class II essential for CD4 survival. " Nat.Immunol. 2: 136-137.

53. Nesic, D. and S.Vukmanovic (1998). MHC class I is required for peripheral accumulation of CD8+ thymic emigrants . J.Immunol. 160 :3705-3712.

54. Zinkernagel, R.M., H.P.Pircher, P.Ohashi, S.Oehen, B.Odermatt, T.Mak, H.Arnheiter, K.Burki, and H.Hengartner (1991). "T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease" . Immunol.Rev. 122: 133-171.

55. Steinhoff, U., K.J.Maloy, C.Burkhart, A.J.Clark, T.Rulicke, H.Hengartner, and R.M.Zinkernagel (1999). "Variable immune response against a developmentally regulated self-antigen" . J Autoimmun. 12: 27-34.


© Die inhaltliche Zusammenstellung und Aufmachung dieser Publikation sowie die elektronische Verarbeitung sind urheberrechtlich geschützt. Jede Verwertung, die nicht ausdrücklich vom Urheberrechtsgesetz zugelassen ist, bedarf der vorherigen Zustimmung. Das gilt insbesondere für die Vervielfältigung, die Bearbeitung und Einspeicherung und Verarbeitung in elektronische Systeme.

DiML DTD Version 2.0
Zertifizierter Dokumentenserver
der Humboldt-Universität zu Berlin
HTML - Version erstellt am:
Thu Feb 20 11:23:24 2003