Ullrich, Oliver: Mechanismen protektiver und destruktiver Funktionen der Poly(ADP-Ribose)-Polymerase-1 (PARP-1) bei Zell- und Gewebeschädigungen

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Literaturverzeichnis

Akiyama H, Kawamata T, Yamada T, Tooyama I, Ishii T and McGeer PL. "Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer´s disease and some other degenerative neurological disorders. " Acta Neuropathol. Berl. 85, 628-634 (1993)

Albrich JM, McCarthy CA and Hurst JK. "Biological reactivity of hypochlorous acid: Implications for microbicidal mechanisms of leukocyte myeloperoxidase." Proc. Natl. Acad. Sci. USA 78, 210-214 (1981)

Altman SA, Zastawny L, Cacciuttolo MA, Akman SA, Dizdaroglu M and Rao G. "Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions. " Free Radic. Biol. Med. 19, 897-902 (1995)

Alvarez-Gonzalez R, Althaus FR. "Poly(ADP-ribose) catabolism in mammalian cells exposed to DNA-damaging agents" Mutat. Res. 218, 67-74 (1989)

Ame JC, Rolli V, Schreiber V, et al. "PARP-2: A novel mammalian DNA-damage-dependent poly(ADP-ribose) polymerase." J. Biol. Chem. 274, 17860-17868 (1999)

Ame JC, Rolli V, Schreiber V, Niedergang C, Apiou F, Decker P, Muller S, Hoger T, Menissier-de Murcia J, de Murcia G. "PARP-2, a novel mammalian DNA-damage-dependent poly(ADP-ribose) polymerase " J. Biol. Chem. 274, 17860-17868 (1999)

Arribas J and Castano JG. "Kinetic studies of the differential effect of detergents on the peptidase activities of the multicatalytic proteinase from rat liver." J. Biol. Chem. 265, 13969-13973 (1990)

Babiychuk E, Cottrill PB, Storozhenko S, Fuangthong M, Chen Y, O'Farrell MK, Van Montagu M, Inze D, Kushnir S. "Higher plants possess two structurally different poly(ADP-ribose) polymerases" Plant J. 15, 635-645 (1998)


64

Bechmann I and Nitsch R. "astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: a light, confocal, and electron microscopical study using a phagocytosis-dependent labeling technique. " Glia 20, 145-154 (1997)

Berger NA, Berger SJ, Gerson SL. "DNA repair, ADP-ribosylation and pyridine nucleotide metabolism as targets for cancer chemotherapy." Anticancer Drug Des. 2, 203-209 (1987)

Berger NA. "Poly(ADP-ribose) in the cellular response to DNA damage " Radiat. Res. 101, 4-15 (1985)

Berghammer H, Ebner M, Marksteiner R, Auer B "pADPRT-2: A novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans" FEBS Lett. 449 259-263 (1999)

Berry DM, Williams K, Meckling-Gill KA. "All-trans-retinoic acid induces apoptosis in acute promyelocytic NB4 cells when combined with isoquinolinediol, a poly(ADP-ribose) polymerase inhibitor. " Leuk. Res. 24, 307-316 (2000)

Bhatia M, Kirkland JB and Meckling-Gill KA: "Overexpression of poly(ADP-ribose)polymerase promotes cell cycle arrest and inhibits neutrophilic differentiation of NB4 acute promyelocytic leukemia cells. " Cell Growth Differ. 7, 91-100 (1996)

Bielinska A, Kukowska-Latallo JF, Johnson J, Tomalia DA and Baker JR. "Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers. " Nucleic Acid. Res. 24, 2176-2182 (1996)

Bielinska A, Kukowska-Latallo JF and Baker JR. "The interaction of plasmid DNA mit polyamidoamine dendrimers: mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA. " Biochim. Biophys. Acta 1353, 180-190 (1997)

Boulikas T. "Poly(ADP-ribosyl)ation, DNA strand breaks, chromatin and cancer. " Toxicol Lett. 67, 129-150 (1993)


65

Bowes J, Piper J, Thiemermann C. "Inhibitors of the activity of poly (ADP-ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts " Br. J. Pharmacol. 124, 1760-1766 (1998)

Bowman KJ, Newell DR, Calvert AH, Curtin NJ. "Differential effects of the poly(ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II cytotoxicity in L1210 cells in vitro. " Br. J. Cancer 84, 106-112 (2001)

Burkart V, Kolb H. "Protection of islet cells from inflammatory cell death in vitro " Clin. Exp. Immunol. 93 273-278 (1993)

Burkart V, Wang ZQ, Radons J, Heller B, Herceg Z, Stingl L, Wagner EF, Kolb H. "Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin " Nature Med. 5, 314-319 (1999)

Cagnin A, Brooks DJ, Kennedy AM, Gunn RN, Myers R, Turkheimer FE. "In vivo measurement of activated microglia in dementia. " Lancet 358, 461-467 (2001)

Cantoni O, Cattabeni F, Stocchi V, Meyn RE, Cerutti P and Murray D. "Hydrogen peroxide insult in cultured mammalian cells: relationships between DNA single-strand breakage, poly(ADP-ribose) metabolism and cell killing. Biochem. " Biophys. Acta 1014, 1-7 (1989)

Cervantes-Laurean D, Jacobson EL and Jacobson MK. "Glycation and glycoxidation of histones by ADP-ribose. " J. Biol. Chem. 271, 10461-10469 (1996)

Chambon P, Weill JD, Mandel P. "Nicotinamide mononucleotide activation of new DNA-dependent polyadenylic acid synthesizing nuclear enzyme " Biochem. Biophys. Res. Commun. 11, 39-43 (1963)

Chambon P, Doly JD, Strosser MT and Mandel P. Biochem. Biophys. Res. Commun. 25, 638-643 (1966).

Champlin R, Gale RP. "Acute myelogenous leukemia: recent advances in therapy. " Blood 69, 1551-1562 (1987)


66

Charriaut-Marlangue C, Aggoun-Zouaoui D, Represa A, Ben-Ari Y. "Apoptotic features of selective neuronal death in ischemia, epilepsy and gp 120 toxicity. " Trends Neurosci. 19, 109-114 (1996)

Chatterjee S, Berger SJ, Berger NA. "Poly(ADP-ribose) polymerase: A guardian of the genome that facilitates DNA repair by protecting against DNA recombination. " Mol. Cell. Biochem. 193, 23-30 (1999)

Chatterjee S, Cheng MF, Berger RB, Berger SJ, Berger NA. "Effect of inhibitors of poly(ADP-ribose)polymerase on the induction of GRP78 and subsequent development of resistance to etoposide. " Cancer Res. 55, 868-873 (1995)

Chi NW, Lodish HF. "Tankryase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles. " J. Biol. Chem. 275, 38437-38444 (2000)

Colton CA. and Gilbert DL. "Production of superoxide anions by a CNS macrophage, the microglia. " FEBS Lett. 223, 284-288 (1987)

Cosi C, Colpaert F, Koek W, Degryse A, Marien M. "Poly(ADP-ribose) polymerase inhibitors protect against MPTP-induced depletions of striatal dopamine and cortical noradrenaline in C57B1/6 mice. " Brain Res. 729, 264-269 (1996)

Cosi C, Suzuki H, Milani D, Facci L, Menegazzi M, Vantini G, Kanai Y, Skaper SD. "Poly(ADP-ribose) polymerase: Early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells " J. Neurosci. Res. 39, 38-46 (1994)

Cottet F, Blanché H, Verasdonck P, Le Gall I, Schächter F, Bürkle A et al. "New polymorphisms in the human poly(ADP-ribose) polymerase-1-oding sequence: lack of association with longevity or with increased cellular poly(ADP-ribosyl)ation capacity. " J. Mol. Med. 78, 431-440 (2000)

Coux O, Tanaka K, Goldberg AL. "Structur and functions of the 20S and the 26S proteasomes. " Annu. Rev. Biochem. 65, 801-847 (1996)

D´Amours D, Desnoyers S, D´Silva I, Poirier GG. "Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. " Biochem J. 342, 249-268 (1999)


67

Davies KJA, Doroshow JH. "Redox cycling of anthracyclines by cardiac mitochondria, I: anthracycline radical formation by NADH dehydrogenase. " J Biol Chem. 261, 3060-3067 (1986)

Davies KJA. "Protein damage and degradation by oxygen radicals. " J. Biol. Chem. 262, 9895-9920 (1987)

de Murcia G, Huletsky A, Lamarre D, Gaudreau A, Pouyet J, Daune M. Poirier GG. "Modulation of chromatin superstructure induced by poly(ADP-ribose) synthesis and degradation " J. Biol. Chem. 261, 7011-7017 (1986)

de Murcia G, Menissier de Murcia J. "Poly(ADP-ribose) polymerase: A molecular nick-sensor " Trends Biochem. Sci. 19, 172-176 (1994)

de Murcia J. M., Niedergang C, Trucco C, Ricoul M, Dutrillaux B, Mark M, Oliver FJ, Masson M, Dierich A, LeMeur M, Walztinger C, Chambon P, de Murcia G. "Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells " Proc. Natl. Acad. Sci. USA 94, 7303-7307 (1997)

DeMurcia G, Shall S. Poly (ADP-Ribosylation) Reactions. From DNA damage and stress signalling to cell death. Oxford University Press , 2000

Doroshow JH, Davies KJA. "Redox cycling of anthracyclins by cardiac mitochondria: II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical. " J. Biol. Chem. 261, 3068-3074 (1986)

Ducrocq S, Benjelloun N, Plotkine M, Ben-Ari Y, Charriaut-Marlange C. "Poly(ADP-ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain. " J. Neurochem. 74, 2504-2511 (2000)

Eguchi Y, Shimizu S, Tsujimoto Y. "Intracellular ATP levels determine cell death fate by apoptosis or necrosis " Cancer Res. 57, 1835-1840 (1997)

Eliasson MJ, Huang Z, Ferrante RJ, Sasamata M, Molliver ME, Snyder SH, Moskowitz MA. "Neuronal nitric oxide synthase activation and peroxynitrite formation in ischemic stroke linked to neural damage " J. Neurosci. 19, 5910-5918 (1999)


68

Eliasson MJ, Sampei K, Mandir AS, Hurn PD, Traystman RJ, Bao J, Pieper A, Wang ZQ, Dawson TM, Snyder SH, Dawson VL. "Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia " Nature Med. 3, 1089-1095 (1997)

Endres M, Wang ZQ, Namura S, Waeber C, Moskowitz MA. "Ischemic brain injury is mediated by the activation of poly(ADP- ribose)polymerase " J. Cereb. Blood Flow Metab. 17 1143-1151 (1997)

Enright HU, Miller WJ, Hebbel RP. "Nucleosomal histone proteins protects DNA from iron-mediated damage. " Nucleic Acid Res. 20, 3341-3346 (1992)

Esterbauer H, Schaur RJ, Zollner H. "Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. " Free Radic. Biol. Med. 11, 81-128 (1991)

Feinstein E, Canaani E, Weiner LM. "Dependence of nucleic acid degradation on in situ free-radical production by adriamycin. " Biochemistry 32, 13156-13161 (1993)

Folch E, Salas A, Prats N, Panes J, Pique JM, Gelpi E et al. "H2O2 and PARS mediate lung P-selectin upregulation in acute pancreatitis. " Free Radic. Biol. Med. 28, 1286-1294 (2000)

Fougerousse F, Meloni R, Roudaut C, Beckmann JS. "Dinucleotide repeat polymorphism at the human poly(ADP-ribose) polymerase gene (PPOL). " Nucleic Acid Res. 20, 1166 (1992)

Frechette A. Huletsky A. Aubin RJ, de Murcia G, Mandel P, Lord A, Grondin G, Poirier GG. "Poly(ADP-ribosyl)ation of chromatin: Kinetics of relaxation and its effect on chromatin solubility " Can. J. Biochem. Cell Biol. 63, 764-773 (1985)

Gale EA. "Theory and practice of nicotinamide trials in pre-type 1 diabetes " J. Pediatr. Endocrinol. Metab. 9, 375-379 (1996b)

Gaziew AI, Kutsyi MP. "Gamma-irradiated DNA activates histone H1-specific proteinase of rat liver nuclei. " Int. J. Radiat. Biol. 61, 169-174 (1992)

Goria-Gatti L, Iannone A, Tomasi A, Poli G and Albano E. "In vitro and in vivo evidence for the formation of methyl radical from procarbazine: a spin-trapping "


69

"study. " Carcinogenesis 13, 799-805 (1992)

Grube K, Bürkle A. "Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-species life span. " Proc. Natl. Acad. Sci. USA 89, 11759-11763 (1992)

Grune T, Siems WG, Kowalewski J, Zollner H, Esterbauer H. "Identification of metabolic pathways of the lipid peroxidation product 4-hydroxynonenal by enterocytes of rat small intestine. " Biochem. Int. 25, 963-971 (1991)

Grune T, Siems WG, Zollner H, Esterbauer H. "Metabolism of 4-hydroxynonenal, a cytotoxic lipid peroxidation product, in Ehrlich mouse ascites cells at different proliferation stages. " Cancer Res. 54, 5231-5235 (1992)

Grune T, Blasig IE, Sitte N, Roloff E, Haseloff R and Davies KJA. "Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome. " J. Biol. Chem. 273, 10857-10862 (1998)

Grune T, Reinheckel T, Davies KJA. "Protein degradation in cultured liver epithelial cells during oxidative stress: role of the multicatalytic proteinase complex, proteasome. " J. Biol. Chem. 270, 2344-2351 (1995)

Grune T, Reinheckel T, Davies KJA. "Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. " J. Biol. Chem. 271, 15504-15509 (1996)

Grune T, Reinheckel T, Davies KJA. "Degradation of oxidized proteins in mammalian cells. " FASEB J. 11, 526-534 (1997)

Grune T, Reinheckel T, Joshi M, Davies KJA. "Proteolysis in cultured liver epithelial cells during oxidative stress - Role of the multicatalytic proteinase complex, proteasome. " J. Biol. Chem. 270, 2344-2351 (1995)

Gunjan A, Alexander BT, Sittman DB, Brown DT. "Effects of histone H1 variant overexpression on chromatin structure. " J. Biol. Chem. 274, 37950-37956 (1999)

Ha HC, Snyder SH. "Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion " Proc. Natl. Acad. Sci. USA 96, 13978-13982 (1999)


70

Ha HC, Snyder SH. "Poly(ADP-ribose) polymerase-1 in the nervous system. " Neurobiol. Dis. 7, 225-239 (2000)

Hailer NP, Jarhult JD and Nitsch R. "Resting microglia cell in vitro: analysis of morphology and adhesion molecule expresssion in organotypic hippocampal slice cultures. " Glia 18, 319-331 (1996)

Hailer NP, Bechmann I, Heizmann S and Nitsch R. "Adhesion molecule expression on phagocytic microglial cells following anterograde degeneration of perforant path axons. " Hippocampus 7, 341-349 (1997)

Hailer NP, Heppner FL, Haas D and Nitsch R. "Fluorescent dye pre-labelled microglial cells migrate into hippocampal slice cultures and ramify. " Eur. J. Neurosci. 10, 3284-3290 (1997)

Hailer NP, Heppner FL, Haas D and Nitsch R. "Astrocytic factors deactivate antigen presenting cells that invade the central nervous system. " Brain Pathol. 8, 459-474 (1998)

Hara S, Halicka HD, Bruno S, Gong J, Traganos F, Darzynkiewicz Z. "Effect of protease inhibitors on early events of apoptosis. " Exp. Cell. Res. 223, 372-384 (1996)

Hass R and Lopez-Guerrero J. "Aggressive tumor growth of the human TUR leukemic cells is associated with high levels of c-myc expression and down-regulation of p20-max. " Int. J. Cancer 72, 1113-1116 (1997)

Hass R, Bartels H, Topley N, Hadam M, Köhler L, Goppelt-Strübe M and Resch K, "TPA-induced differentiation and adhesion of U937 cells: changes in ultrastructure, cytoskeletal organization and expression of surface antigens. " Eur. J. Cell Biol. 48, 282-293 (1989)

Hass R, Gunji H, Datta R, Kharbanda S, Hartmann A, Weichselbaum R and Kufe D. "Differentiation and retrodifferentiation of human myeloid leukemia cells is associated with reversible induction of cell cycle regulation genes. " Cancer Res. 52, 1445-1450 (1992)


71

Hass R, Hirano M, Kharbanda S, Rubin E, Meinhardt G and Kufe D. "Resistance to phorbol-ester-induced differentiation of a U937 myleoid leukemia cell variant with a signaling defect upstream to Raf-1 kinase. " Cell Growth Differ. 4, 657-663 (1993)

Hatakeyama K, Nemoto Y, Ueda K, Hayaishi O. "Purification and characterization of poly(ADP-ribose) glycohydrolase: Different modes of action on large and small poly(ADP-ribose) " J. Biol. Chem. 261, 14902-14911 (1986)

Hazen SL, Heinecke JW. "3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. " J. Clin. Invest. 99, 2075-2081 (1997)

Heller B, Wang ZQ. Wagner EF, Radons J, Burkle A, Fehsel K, Burkart V, Kolb H. "Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells " J. Biol. Chem. 270, 11176-11180 (1995)

Heppner FL, Skutella T, Hailer NP, Haas D and Nitsch R. "Activated microglial cells migrate towards the sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures. " Eur. J. Neurosci. 10, 3284-3290 (1998)

Herceg Z, Wang ZQ. "Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis " Mol. Cell. Biol. 19, 5124-5133 (1999)

Hirugashi M, Adachi H, Ohba Y. "Synthesis and degradation of H1 histone subtypes in mouse lymphoma L5178Y cells. " J. Biol. Chem. 262, 13075-13080 (1987)

Hu S, Sheng WS, Peterson PK and Chao CC. "Cytokine modulation of murine microglial cell superoxide production. " Glia 13, 45-50 (1995)

Jacobson MK, Jacobson EL. "Discovering new ADP-ribose polymer cycles: protecting the genome and more. " Trends Biochem. Sci. 24, 415-417 (1999)

Jacobson MK, Althaus F et al. 13th International Symposium on ADP-ribosylation Reactions, June 8-11, 2001, New York, New York USA, www.adpr2001.org/goals.htm


72

Jeggo PA. "DNA repair: PARP - another guardian angel ? " Curr. Biol. 8, R49-R51 (1998)

Jentoft N and Dearborn DG. "Labeling of proteins by reductive methylation using sodium cyanoborohydride. " J. Biol. Chem. 254, 4359-4365 (1979)

Jijon HB, Churchill T, Malfair D, Wessler A, Jewell LD, Parsons HG et al. "Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitis. " Am. J. Physiol Gastrointest. Liver Physiol. 279, G641-651 (2000)

Johansson M. "A human poly(ADP-ribose) polymerase gene family (ADPRTL): cDNA cloning of two novel poly(ADP-ribose) polymerase homologues. " Genomics 57 442-445 (1999)

Jones NJ, Ellard S, Waters R and Parry EM. "Cellullar and chromosomal hypersensitivity to DNA crosslinking agents and toposiomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia teleangiectasia and Fanconi's anaemia cells. " Carcinogenesis 14, 2487-2494 (1993)

Kameoka M, Ota K, Tetsuka T, Tanaka Y, Itaya A, Okamoto T et al. "Evidence for regulation of NF-?B by poly(ADP-ribose) polymerase. " Biochem. J. 346, 641-649 (2000)

Kato T, Suzumura Y, Fukushima M. "Enhancement of bleomycin activity by 3-aminobenzamide, a poly(ADP-ribose) synthesis inhibitor, in vitro and in vivo. " Anticancer Res. 8, 239-243 (1988)

Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE, Poirier GG. "Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. " Cancer Res. 53, 3976-3985 (1993)

Kawamura T, Hanai S, Yokota T , Hayashi T, Poltronieri P, Miwa M, Uchida K. "An alternative form of poly(ADP-ribose) polymerase in Drosophila melanogaster and its ectopic expression in rat-1 cells. " Biochem. Biophys. Res. Commun. 251, 35-40 (1998)


73

Khan AU and Kasha M. "Singlet molecular oxygen evolution upon simple acidification of aqueous hypochlorite: Application to studies on the deleterious health effects of chlorinated drinking water. " Proc. Natl. Acad. Sci. USA 91, 12362-12364 (1994)

Kickhoefer VA, Siva AC, Kedersha NL, Inman EM, Ruland C, Streuli M, Rome LH. "The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase " J. Cell Biol. 146 917-928 (1999)

Kim JW, Kim K, Knag K, Joe CO. "Inhibition of homodimerization of poly(ADP-ribose) polymerase by ist C-terminal cleavage products produced during apoptosis. " J. Biol. Chem. 275, 8121-8125 (2000)

Kirsten E, Bauer PI and Kun E. "Cellular regulation of ADP-ribosylation of proteins. IV. Conversion of poly(ADP-ribose)polymerase activity to NAD-glycohydrolase during retinoic acid-induced differentiation of HL-60 cells. " Exp. Cell. Res. 194, 1-8 (1991)

Kreutzberg GW. "Microglia: a sensor for pathological events in the CNS. " Trends Neurosci. 19, 312-318 (1996)

Kreutzberg GW. "Microglia, the first line of defence in brain pathologies. " Arzneimittelforschung 45, 357-360 (1995)

Krupitza G, Cerutti P. "ADP-ribosylation of ADPR-transferase and topoisomerase I in intact mouse epidermal cells JB6. " Biochemistry 28, 2034-2040 (1989a)

Kukreja RC, Hess ML. "The oxygen free radical system: From equations through membrane-protein interactions to cardiovascular injury and protection. " Cardiovasc. Res. 26, 641-655 (1992)

Kumatori A, Tanaka K, Inamura N, Sone S, Ogura T, Matsumoto T, Tachikawa T, Shin S and Ichihara A. "Abnormally high expression of proteasomes in human leukemic cells. " Proc. Natl. Acad. Sci. USA 87, 7071-7075 (1990)

Lautier D, Lagueux J, Thibodeau J, Menard L, Poirier GG. "Molecular and biochemical features of poly (ADP-ribose) metabolism " Mol. Cell. Biochem. 122, 171-193 (1993)


74

Lee SC, Liu W, Roth P, Dickson DW, Berman JW and Brosnan CF. "Macrophage colony-stimulating factor in human fetal astrocytes and microglia. Differential regulation by cytokines and lipopolysaccharide, and modulation of class II MHC on microglia. " J. Immunol. 150, 594-604 (1993)

Leist M, Single B, Castoldi AF, Kuhnle S, Nicotera P. "Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis " J. Exp. Med. 185, 1481-1486 (1997a)

Leist M, Single B, Kunstle G, Volbracht C, Hentze H, Nicotera P. "Apoptosis in the absence of poly-(ADP-ribose) polymerase " Biochem. Biophys. Res. Commun. 233 518-522 (1997b)

Liaudet L, Szabo A, Soriano FG, Zingarelli B, Szabo C, Salzman AL. "Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia. " Shock 14, 134-141 (2000)

Lindenau J, Noack H, Asayama K and Wolf G. "Enhanced cellular glutathione peroxidase immunoreactivity in activated astrocytes and in microglia during excitotoxin induced neurodegenration. " Glia 24, 252-256 (1998)

Liu J, Ying W, Massa S, Duriez PJ, Swanson RA, Poirier GG et al. "Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains. " Brain Res. Mol. Brain Res. 80, 7-16 (2000)

Love S, Barber R, Wilcock GK. "Increased poly(ADP-ribosyl)ation of nuclear proteins in Alzheimer's disease " Brain 122, 247-253 (1999a)

Love S, Barber R, Wilcock GK. "Neuronal accumulation of poly(ADP-ribose) after brain ischaemia " Neuropathol. Appl. Neurobiol. 25, 98-103 (1999b)

Lowenstein CJ, Alley EW, Raval P, Snowman AM, Snyder SH, Russell SW, Murphy WJ. "Macrophage nitric oxide synthase gene: Two upstream regions mediate induction by interferon gamma and lipopolysaccharide " Proc. Natl. Acad. Sci. USA 90, 9730-9734 (1993)


75

Ludwig A, Behnke B, Holtlund J, Hilz H. "Immunoquantitation and size determination of intrinsic poly(ADP-ribose) polymerase from acid precipitates: An analysis of the in vivo status in mammalian species and in lower eukaryotes " J. Biol. Chem. 263, 6993-6999 (1988)

Ly DH, Lockhart DJ, Lerner RA, Schutz PG. "Mitotic misregulation and human aging. " Science 287, 2486-2492 (2000)

Mabuchi T et al. "Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats. " Stroke 31, 1735-1743 (2000)

Mahajan PB, Zuo Z. "Purification and cDNA cloning of maize Poly(ADP)-ribose polymerase " Plant Physiol. 118, 895-905 (1998)

Mandir AS, Przedborski S, Jackson-Lewis V, Wang ZQ, Simbulan-Rosenthal CM, Smulson ME, Hoffman BE, Guastella DB, Dawson VL, Dawson TM. "Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism " Proc. Natl. Acad. Sci. USA 96, 5774-5779 (1999)

Mandir AS, Poitras MF, Berliner AR, Herring WJ, Guastella DB, Feldman A et al. "NMDA but not non-NMDA excitotoxicity is mediated by poly(ADP-ribose) polymerase. " J. Neurosci. 20, 8005-8511 (2000)

Marcillat O, Zhang Y, Davies KJA. "Oxidative and non-oxidative mechanisms in the inactivation of cardiac mitochondrial electron transport chain components by doxorubicin. " Biochem J. 259, 181-189 (1989)

Masutani M, Suzuki H, Kamada N, Watanabe M, Ueda O, Nozaki T, Jishage K, Watanabe T, Sugimoto T, Nakagama H, Ochiya T, Sugimura T. "Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes " Proc. Natl. Acad. Sci. USA 96, 2301-2304 (1999)

Masutani M, Nazaki T, Nakmoto K, Nakagama H, Suzuki H, Kusuoka O et al. "The response of PARP knockout mice against DNA damaging agents. " Mutat. Res. 462, 159-166 (2000)


76

McConkey DJ. "Calcium-dependent, interleukin-1-converting enzyme inhibitor-insensitive degradation of laminin B1 and DNA fragmentation in isolated thymocyte nuclei. " J. Biol. Chem. 271, 22398-22406 (1996)

Mellgren RL. "Proteolysis of nuclear proteins by µ-calpain and m-calpain. " J. Biol. Chem. 266, 133920-13924 (1991)

Mendoza-Alvarez H, Alvarez-Gonzales R. "Poly(ADP-ribose) polymerase is a catalytic dimer and the automodification reaction in intermolecular. " J. Biol. Chem. 268, 22575-22580 (1993)

Messmer UK, Lapetina EG and Brune B. "Nitric oxide-induced apoposis in RAW 264.7 macrophages is antagonized by protein kinase C- and protein kinase A-activating compounds. " Mol. Pharmacol. 47, 757-765 (1995)

Meyer R, Müller M, Beneke S, Küpper JH, Bürkle A. "Negative regulation of alkylation-induced sister-chromatid exchange by poly(ADP-ribose) polymerase-1 activity. " Int. J. Cancer 88, 351-355 (2000)

Minaga T and Kun E. "Spectral analysis of the conformation of polyadenosine diphosphoribose. Evidence indicating secondary structure. " J. Biol. Chem. 258, 725-730 (1983)

Miwa M, Sugimura T. "Splitting of the ribose-ribose linkage of poly(adenosine diphosphate-robose) by a calf thymus extract " J. Biol. Chem. 246, 6362-6364 (1971)

Miwa M, Ishihara M, Takishima S, Takasuka N, Maeda M, Yamaizumi Z, Sugimura T, Yokoyama S and Miyazawa T. "The branching and linear portions of poly(adenosine diphosphate ribose) have the same alpha(1 leads to 2) ribose-ribose linkage. " J. Biol. Chem. 256, 2916-2921 (1981)

Muiras ML, Bürkle A. "Defending genome integrity over life span: A proprosed role for PARP-1. " Exp. Gerontol. 35, 703-709 (2000)

Nagao M, Nakayasu M, Aonuma S, Shima H, Sugimura T. "Loss of amplified genes by poly(ADP-ribose)poylmerase inhibitors. " Environ Health Perspect. 93, 169-174 (1991)


77

Nagayama T, Simon RP, Chen D, Henshall DC, Pei W, Stetler RA et al. "Activation of poly (ADP-ribose) polymerase in the rat hippocampus may contribute to cellular recovery following sublethal transient global ischemia. " J. Neurochem. 74, 1636-1645 (2000)

Noack H, Lindenau J, Rothe F, Asayama K and Wolf G. "Differential expression of superoxide dismutase isoforms in neuronal and glial compartments in the course of excitotoxically mediated neurodegeneration: relation to oxidative and nitrergic stress. " Glia 23, 285-297 (1998).

Niedergang CP, de Murcia G, Ittel ME, Pouyet J, Mandel P. "Time course of polynucleosome relaxation and ADP-ribosylation: Correlation between relaxation and histone H1 hyper-ADP-ribosylation " Eur. J. Biochem. 146, 185-191 (1985)

Odaka C, Mizuochi T. "Role of macrophage lysosomal enzymes in the degradation of nucleosomes of apoptotic cells. " J. Immunol. 163, 5346-5352 (1999)

Oliver F, Menissier-de-Murcia J, Nacci C, Decker P, Andriantsitohaina R, Muller S, de la Rubia G, Stoclet JC, de Murcia G. "Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice " EMBO J. 18, 4446-4454 (1999)

Oppenheim RW. "Cell death during development of the nervous system " Annu. Rev. Neurosci. 14, 453-501 (1991)

Perry VH, Matyszak MK and Fearn S. "Altered antigen expression of microglia in the aged rodent CNS. " Glia 7, 60-67 (1993)

Pieper AA, Brat DJ, Krug DK, Watkins CC, Gupta A, Blackshaw S, Verma A, Wang ZQ, Snyder SH. "Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes " Proc. Natl. Acad. Sci. USA 96, 3059-3064 (1999a)

Pieper AA, Walles T, Wei G, Clements EE, Verma A, Snyder SH, Zweier J. "(2000) Myocardial postischemic injury is reduced by polyADPribose polymerase-1 gene disruption " Mol. Med. 6(4), 271-82 (2000)


78

Plaschke K, Kopitz J, Weigand MA, Martin E, Bardenheuer HJ. "The neuroprotective effect of cerebral poly(ADP-ribose) polymerase inhibition in a rat model of global ischemia. " Neurosci. Lett. 284, 109-112 (2000)

Pleschke JM, Kleczkowska HE, Strohm M, Althaus FR. "Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins. " J. Biol. Chem. 275, 40974-40980 (2000)

Plummer SM and Faux SP. "Induction of 8-hydroxydeoxyguanosine in isolated DNA and HeLa cells exposed to fecapentaene-12: evidence for the involvement of prostaglandin H synthetase and iron. " Carcinogenesis 15, 449-453 (1994)

Preisler HD, Anderson K, Rai K, et al. "The frequency of long-term remission in patients with acute myelogenous leukemia treated with concentional maintenance chemotherapy: a study of 760 patients with a minimal follow-up time of 6 years. " Br J Haematol. 71, 189-194 (1989)

Quesada P, Atorino L, Cardone A, Ciarcia G and Farina B. "Poly(ADP-ribosyl)ation system in rat germinal cells at different stages of differentiation. " Exp. Cell. Res. 226, 183-190 (1996)

Realini CA and Althaus FR. "Histone shuttling by poly(ADP-ribosylation). " J. Biol. Chem. 267, 18858-18865 (1992)

Reinheckel T, Ullrich O, Sitte N and Grune T. "Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress. " Arch. Biochem. Biophys. 377, 65-68 (2000)

Rovera G, O'Brian TA and Diamond L. "Induction of differentiation in human promyelocytic leukemia cells by tumor promoters. " Science 204, 868-870 (1979)

Ruf A, de Murcia G, Schulz GE. "Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling. " Biochemistry 37, 3893-3900 (1998)

Sallmann FR, Vodenicharov MD, Wang ZQ, Poirier GG. "Characterization of sPARP-1 " J. Biol. Chem. 275, 15504-15511 (2000)


79

Satoh MS and Lindahl T. "Role of poly(ADP-ribose) formation in DNA repair. " Nature (London) 356, 356-358 (1992)

Schubert P and Rudolphi K. "Interfering with the pathologic activation of microglial cells and astrocytes in dementia. " Alzheimer Dis. Assoc. Disord. 12, Suppl. 2, S21-S28 (1998)

Selle A, Ullrich O, Hass R. "Retrodifferentiation of human leukemic cells is mediated by poly-ADP-ribose-polymerase. " 5th Joint Meeting of the German Signal Transduction Society , Weimar, Germany (2001)

Selley ML, Bourne DJ, Bartlett MR, Tymms KE, Brook AS, Duffield AM, Ardlie NG. "Occurrence of (E)-4-hydroxy-2-nonenal in plasma and synovial fluid of patients with rheumatoid arthritis and osteoarthritis. " Ann. Rheum. Dis. 51, 481-484 (1992)

Shall S, de Murcia G. "Poly(ADP-ribose) polymerse-1: what have we learned from the deficient mouse model ? " Mutat. Res. 460, 1-15 (2000)

She ZW, Wewers MD, Herzyk DJ and Davies WB. "Tumor necrosis factor increases the elastolytic potential of adherent neutrophils: A role for hypochlorous acid. " Am. J. Respir. Cell. Mol. Biol. 9, 386-392 (1993)

Shieh WM, Ame JC, Wilson MV, Wang ZQ, Koh DW, Jacobson MK et al. "Poly(ADP.-ribose) polymerase null mouse cells synthesize ADP-ribose polymers. " J. Biol. Chem. 273, 30069-30072 (1998)

Siems WG, Zollner H, Esterbauer H. "Metabolic pathways of the lipid peroxidation product 4-hydroxynonenal by enterocytes of rat small intestine. " Biochem. Int. 25, 963-971 (1991)

Simbulan-Rosenthal CM, Rosenthal DS, Iyer S, Boulares H and Smulson ME. "Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication. " Mol. Cell. Biochem. 193, 137-148 (1999)

Simbulan-Rosenthal CM, Ly DH, Rosenthal DS, Konopka G, Luo R, Wang ZQ et al. "Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase. " Proc. Natl. Acad. Sci. USA 97, 11274-11279 (2000)


80

Simbulan-Rosenthal CM, Rosenthal DS, Luo R, Li JH, Zhang J, Smulson ME. "Inhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy. " Nucleic Acids Res. 29, 841-849 (2001)

Sinha BK and Mimnaugh EG. "Free radicals and anticancer drug resistance: oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors. " Free Radical Biol. Med. 8, 567-581 (1990)

Sinha BK, Mimnaugh EG. "Free radicals and anticancer drug resistance; oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors. " Free Radic Biol Med. 8, 567-581 (1990)

Smith S, Giriat I, Schmitt A, de Lange T. "Tankyrase, a poly(ADP-ribose) polymerase at human telomeres " Science 282, 1484-1487 (1998)

Smith S, de Lange T. "Tankryase promotes telomere elongation in human cells. " Curr. Biol. 10, 129-302 (2000)

Smith S. "The world according to PARP. " Trends Biochem. Sci. 26, 174-179 (2001)

Soldatenkov VA, Albor A, Patel BK, Dreszer R, Dritschilo A, Notario V. "Regulation of the human poly(ADP-ribose) polymerase promotor by the ETS transcription factor. " Oncogene 18, 3954-3962 (1999)

Stohwasser R, Giesebrecht J, Kraft R, Muller EC, Hausler KG, Kettenmann H, Hanisch UK and Kloetzel PM. "Biochemical analysis of proteasomes from mouse microglia: induction of immunoproteasomes by interferon-gamma and lipopolysaccharide. " Glia 29, 355-365 (2000)

Stoll G, Jander S and Schroeter M. "Inflammation and glial responses in ischemic brain lesions. " Prog. Neurobiol. 56, 149-171 (1998)

Strosznajder JB, Jesko H, Strosznajder RP. "Age-related alteration of poly(ADP-ribose) polymerase activity in different parts of the brain. " Acta Biohcim. Pol. 47, 331-337 (2000)

Sugaya K, Chouinard M and McKinney M. "Immunostimulation protects microglial cells from nitric oxide-mediated apoptosis. " Neuroreport 8, 2241-2245 (1997)


81

Szabo C, Lim LH, Cuzzocrea S, Getting SJ, Zingarelli B, Flower RJ, Salzman AL, Perretti M. "Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects " J. Exp. Med. 186, 1041-1049 (1997)

Szabo C, Zingarelli B, Salzman AL. "Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite " Circ. Res. 78, 1051-1063 (1996)

Takahashi K, Pieper AA, Croul SE, Zhang J, Snyder SH, Greenberg JH. "Post-treatment with an inhibitor of poly(ADP-ribose) polymerase attenuates cerebral damage in focal ischemia " Brain Res. 829, 46-54 (1999)

Tentori L, Lacal PM, Benincasa E, et al. "Role of wild-type p53 on the antineoplastic activity of temozolomide alone or combined with inhibitors of poly(ADP-ribose)polymerase. " J Pharmacol Exp Ther. 285, 884-893 (1998)

Test ST and Weiss SJ. "The generation of utilization of chlorinated oxidants by human neutrophils. " Adv. Free Radical Biol. Med. 2, 91-116 (1986)

Thomas JO. "Histone H1: location and role. " Curr. Opin. Cell. Biol. 11, 312-317 (1999)

Tomoda T, Kurashige T and Taniguchi T. "Inhibition of interferon-gamma- and phorbol-ester-induced HLA-DR and interleukin-1 production by the expression of a transfected poly(ADP-ribose) synthetase gene in human leukemia THP-1 cells. " Biochem. Biophys. Acta 1135, 79-83 (1992)

Toyokuni S, Okamoto K and Yodoi J. "Persistent oxidative stress in cancer. " FEBS Lett. 358, 1-3 (1995)

Tsvetkov S, Ivanova E, Djondjurov L. "Metabolic behaviors of the core histones in proliferating Friend cells. " Exp. Cell Res. 180, 94-105 (1989)

Tsutsumi M, Masutani M, Nozaki T, Kusuoka O, Tsujichi T, Nakagama H et al. "Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout mice to nitrosamine carcinogenicity. " Carcinogenesis 22, 1-3 (2001)


82

Urade M, Sugi M and Miyazaki T. "Establishment of three bleomycin-resistant human carcinoma cell lines and their cross-resistance to other antitumor agents. " Cancer 61, 1501-1507 (1988)

Ursini MV, Parrella A, Rosa G, Salzano S and Martini G. "Enhanced expression of glucose-6-phosphate dehydrogenase in human cells sustaining oxidative stress. " Biochem. J. 323, 801-806 (1997)

Voelkel-Johnson C, Entingh AJ, Wold WS, Gooding LR, Laster SM. "Activation of intracellular proteases is an early event in TNF-induced apoptosis. " J. Immunol. 154, 1707-1716 (1995)

Wang P, Zweier JL. "Measurement of nitric oxide and peroxynitrite generation in the postischemic heart: Evidence for peroxynitrite-mediated reperfusion injury " J. Biol. Chem. 271, 29223-29230 (1996)

Waterborg JH. "Histone synthesis and turnover in alfalfa. " J. Biol. Che. 268, 4912-4917 (1993)

Watson CY, Whish WJ, Threadgill MD. "Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP). " Bioorg Med Chem. 6, 721-734 (1998)

Weiss SJ and LoBuglio AF. "Biology of disease. Phagocyte generated oxygen metabolites and cellular injury. " Lab. Inv. 47, 5-18 (1982)

Wielckens K, Schmidt A, George B, Bredehorst R and Hilz H. "DNA fragmentation and NAD depletion. Their relation to the turnover of endogenous mono(ADP-ribosyl) and poly(ADP-ribosyl) proteins. " J. Biol. Chem. 257, 12872-12877 (1982)

Wolffe AP. "Histone H1. " Int. J. Biochem. Cell. Biol. 29, 1463-1466 (1997)

Wondrak GT, Cervantes-Laurean D, Jacobson EL, Jacobson MK. "Histone carbonylation in vivo and in vitro. " Biochem. J. 351, 769-777 (2000)

Yakovlev AG, Wang G, Stoica BA, Boulares HA, Spoonde AY, Yoshihara K et al. "A role of the Ca2+/Mg2+ -dependent endonuclease in apoptosis and ist inhibition by poly(ADP-ribose) polymerase. " J. Biol. Chem. 275, 21302-21308 (2000)


83

Yan SD, Chen Y, Fu J, Chen M, Zhu H, Roher A, Slattery T, Zhao L, Nagashima M, Morser J, Migheli A, Nawroth P, Stern P and Schmidt AM. "RAGE and amyloid-beta peptide neurotoxicity in Alzheimer´s disease. " Nature 382, 685-691 (1996)

Zhang J, Dawson VL, Dawson TM, Snyder SH. "Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. " Science 263, 687-689 (1994)

Zhang J, Pieper A, Snyder SH. "Poly(ADP-ribose) synthetase activation: An early indicator of neurotoxic DNA damage " J. Neurochem. 65, 1411-1414 (1995)

Zhang J, Lautar S, Hunag S, Ramsey C, Cheung A, Li JH. "GPI 6150 prevents H2O2 cytotoxicity by inhibiting poly(ADP-ribose) polymerase. " Biochem. Biophys. Res. Commun. 278, 590-598 (2000)

Zielasik J, Archelos JJ, Toyka KV and Hartung HP. "Expression of intercellular adhesion molecule-1 on rat microglial cells. " Neurosci. Lett. 153, 136-139 (1993)

Zingarelli B, Cuzzocrea S, Zsengeller Z, Salzman AL, Szabo C. "Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase " Cardiovasc. Res. 36, 205-215 (1997)

Zingarelli B, Salzman AL, Szabo C. "Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. " Circ. Res. 83, 85-94 (1998)

Zingarelli B, Szabo C, Salzman AL. "Blockade of poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis " Gastroenterology 116, 335-345 (1999)


84

Zitierte eigene Arbeiten

O.Ullrich, T.Grune, W.Henke, H.Esterbauer, W.G.Siems. "Identification of metabolic pathways of the lipid peroxidation product 4-hydroxynonenal by mitochondria isolated from rat kidney cortex. " FEBS Lett. 352, 84-86 (1994)

O.Ullrich, T.Grune, W.Henke, H.Esterbauer, W.G.Siems. "The effect of the cytotoxic lipid peroxidation product 4-hydroxynonenal and its metabolite 4-hydroxynonenoic acid on respiration of isolated rat kidney cortex mitochondria. " Free Radical Res. 24(6), 421-427 (1996)

O.Ullrich, T.Grune, K.Lehmann, H.Huser, W.Ehrlich, W.G.Siems. "Inhibition of the poly(ADP-ribose) formation by 4-hydroxynonenal in primary cultures of rabbit synovial fibroblasts. " Biochem. J. 315(3), 705-708 (1996)

O.Ullrich, H.Huser, W.Ehrlich, T.Grune. "Intracellular metabolism of 4-hydroxynonenal in primary cultures of rabbit synovial fibroblasts. " Free Radical Biol. Med. 22(7), 1153-1157 (1997a)

O.Ullrich, T.Grune. "Detection of 8-hydroxy-deoxyguanosine in K562 human hematopoietic cells by high performance capillary electrophoresis. " J. Chrom. B 697, 243-249 (1997b)

O.Sommerburg, O.Ullrich, N.Sitte, W.Siems, T.Grune. "Dose- and wavelength-dependent oxidation of crystallins by UV light - Selective recognition and degradation by the 20S proteasome. " Free Radical Biol. Med. 24(9), 1369-1374 (1998a)

T.Reinheckel, N.Sitte, O.Ullrich, U.Kuckelkorn, K.J.A.Davies, T.Grune. "Resistance of the 20S proteasome to oxidative stress - comparison of the activities of the 20S and 26S proteasome. " Biochem. J. 335, 637-642 (1998b)

O.Ullrich, N.Sitte, O.Sommerburg, V.Sandig, T.Grune. "Influence of DNA binding on the degradation of oxidized histones by the 20S proteasome. " Arch. Biochem. Biophys. 362(2), 21-216 (1999a)


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O.Ullrich, T.Reinheckel, N.Sitte, R.Hass, T.Grune. "Poly-ADP-ribose-polymerase activates nuclear proteasome to degrade oxidatively damaged histones. " Proc. Natl. Acad. Sci. U.S.A. 96, 6223-6228 (1999b)

P. Meyer-Kuckuk, O.Ullrich, T.Grune, M. Ziegler, M.Schweiger. "Functional interaction of poly(ADP-ribose) with the 20S proteasome in vitro. " Biochem. Biophys. Res. Comms. 259, 576-581 (1999c)

O.Ullrich, T.Reinheckel, N.Sitte, T.Grune. "Degradation of hypochlorite damaged glucose-6-phosphate dehydrogenase by the 20S proteasome. " Free Radical Biol. Med. 27, 487-492 (1999d)

T.Reinheckel, O.Ullrich, N.Sitte, T.Grune. "Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress. " Arch. Biochem. Biophys. 377(1), 65-68, (2000a)

O.Ullrich, Ö.Ciftci, R.Hass. "Proteasome activation by poly-ADP-ribose-polymerase in human myelomonocytic cells after oxidative stress. " Free Radical Biol. Med. 29(10), 995-1004 (2000b)

J.Mehlhase, J.Gieche, O.Ullrich, N.Sitte, T.Grune. "LPS-induced protein oxidation and proteolysis in BV-2 microglial cells. " IUBMB Life 50(4-5), 331-335 (2000c)

P.Lasch, T.Petras, O.Ullrich, J.Backmann, D.Naumann, T.Grune. "Hydrogen peroxide- induced structural alterations of RNase " A J. Biol. Chem. 276, 9492-9502 (2001a)

Ö.Ciftci, O.Ullrich*, C.A.Schmidt, A.Diestel, R.Hass. "Regulation of the nuclear proteasome activity in human leukemia cells after adriamycin-treatment. " Blood 97(9) , 2830-2838 (2001b)

O.Ullrich, A.Diestel, I.Bechmann, M.Homberg, T.Grune, R.Hass, R.Nitsch. "Turnover of oxidatively-damaged proteins in BV-2 microglia cells is linked to their activation state by poly(ADP-ribose) polymerase" . FASEB J. 15, 1460-1462 (2001) online: 10.1096/fj.00-0540.fje (April 27, 2001c)


86

O.Ullrich, T.Grune. "Proteasomal degradation of oxidatively-damaged endogenous histones in K562 human leukemic cells. " Free Radic. Biol. Med. 31, 887-893 (2001d)

O.Ullrich, A.Diestel, I.Y.Eyüpoglu, R.Nitsch. "Regulation of microglial expression of integrins by poly(ADP-ribose)polymerase-1. " Nature Cell Biol. 3, 1035-1042 (2001e)


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