Wagner, Frank-Dietrich: Therapieprinzipien zur Unterstützung der rechtsventrikulären Funktion nach Implantation eines linksventrikulären Assist Device

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Literatur

1. Funk M. "Epidemiology of end-stage heart disease." In: Hogness JR, Vanantwerp M, eds. The artificial heart: prototypes, policies, and patients. Washington: National Academic Press, 1991: 251-261.

2. McKee PA, Castelli WP, McNamara PM, Kannel WB. "The natural history of congestive heart failure: the Framingham study. " New England Journal of Medicine 1971; 285: 1441-1446.

3. Kannel WB, Savage D, Castelli WP. "Cardiac failure in the Framingham study: twenty-year follow-up. " In: Braunwald E, Mock MB, Watson JT, eds. Congestive heart failure. New York: Grune & Stratton, 1981: 15-30.

4. The CONSENSUS Trial Study Group. "Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). " New England Journal of Medicine 1987; 316: 1429-1435.

5. The SOLVD Investigators. "Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. " New England Journal of Medicine 1991; 325: 293-302.

6. Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ, Cuddy TE, Davis BR, Geltman EM, Goldman S, Flaker GC, Klein M, Lamas GA, Packer M, Rouleau J, Rouleau JL, Rutherford J, Wertheimer JH, Hawkins CM. "Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. New England Journal of Medicine " 1992; 327: 669-677.

7. Packer M, Greenberg B, Massie B, Dash H. "Deleterious effects of hydralazine in patients with pulmonary hypertension. " New England Journal of Medicine 1982; 306: 1326-1331.

8. Hogness JR. Preface. In: Hogness JR, Vanantwerp M, eds. The artificial heart: prototypes, policies, and patients. Washington: National Academic Press, 1991: i-x.

9. Kaye MP. "The Registry of the International Society for Heart and Lung Transplantation: ninth official report - 1992. " Journal of Heart and Lung Transplantation 1992; 11: 599-606.

10. Young JB, Naftel DC, Bourge RC, Kirklin JK, Clemson BS, Porter CB, Rodeheffer RJ, Kenzora JL. "Matching the heart donor and heart transplant recipient. Clues for successful expansion of the donor pool: a multivariable, multiinstitutional report. The "


113

"Cardiac Transplant Research Database Group. " Journal of Heart and Lung Transplantation 1994; 13: 353-365.

11. McCarthy PM, James KB, Savage RM, Vargo R, Kendall K, Harasaki H, Hobbs RE, Pashkow FJ. "Implantable left ventricular assist device. Approaching an alternative for end-stage heart failure. Implantable LVAD Study Group. " Circulation 1994; 90(Suppl 2): II-83-II-86.

12. Hogness JR. "Clinical effectiveness and need for long-term circulatory support." In: Hogness JR, Vanantwerp M, eds. The artificial heart: prototypes, policies, and patients. Washington: National Academic Press, 1991: 65-84.

13. Gibbon JH. "Application of a mechanical heart and lung apparatus to cardiac surgery." Minnesota Medicine 1954; 37: 171-185.

14. Stuckey JH, Newman MM, Dennis C, Berg EH, Goodman SE, Fries CC, Karlson KE, Blumenfeld M, Weitzner SW, Binder LS, Winston A. "The use of the heart-lung machine in selected cases of acute myocardial infarction." Surgical Forum 1957; 8: 342-344.

15. Cooley DA, Beall AC, Alexander JK. "Acute massive pulmonary embolism: successful surgical treatment using temporary cardiopulmonary bypass." Journal of the American Medical Association 1961; 177: 283-286.

16. Spencer FC, Eiseman B, Trinkle JK, Rossi NP. "Assisted circulation for cardiac failure following intracardiac surgery with cardiopulmonary bypass." Journal of Thoracic and Cardiovascular Surgery 1965; 49: 56-73.

17. Dennis C, Carlens E, Senning A, Hall DP, Moreno HP, Cappelletti RR, Wesolowski SA. "Clinical use of a cannula for left heart bypass without thoracotomy: experimental protection against fibrillation by left heart bypass. " Annals of Surgery 1962; 156: 623-637.

18. DeBakey ME. "Left ventricular bypass pump for cardiac assistance. Clinical experience. " American Journal of Cardiology 1971; 27: 3-11.

19. Moulopoulos SD, Topaz S, Kolff WJ. "Diastolic balloon pumping (with carbon dioxide) in the aorta - a mechanical assistance to the failing circulation." American Heart Journal 1962; 63: 669-675.

20. Kantrowitz A, Tjonneland S, Freed PS, Phillips SJ, Butner AN, Sherman JL. "Initial clinical experience with intraaortic balloon pumping in cardiogenic shock. " Journal of the American Medical Association 1968; 203: 113-118.


114

21. The Working Group on Mechanical Circulatory Support of the National Heart Lung and Blood Institute. "Artificial heart and assist devices: directions, needs, costs, societal and ethical issues. " Bethesda: National Institutes of Health; 1985. Report No.: NIH-NHLBI-85-2723: 9.

22. Starnes VA, Oyer PE, Portner PM, Ramasamy N, Miller PJ, Stinson EB, Baldwin JC, Ream AK, Wyner J, Shumway NE. "Isolated left ventricular assist as bridge to cardiac transplantation." Journal of Thoracic and Cardiovascular Surgery 1988; 96: 62-71.

23. Boujoukos AJ, Martich GD. "Mechanical circulatory assist devices." Journal of Intensive Care Medicine 1996; 11: 23-36.

24. Hetzer R, Hennig E, Schiessler A, Friedel N, Warnecke H, Adt M. "Mechanical circulatory support and heart transplantation." Journal of Heart and Lung Transplantation 1992; 11(Suppl): S175-S181.

25. Friedel N, Viazis P, Schiessler A, Warnecke H, Hennig E, Hetzer R. "Patient selection for mechanical circulatory support as a bridge to cardiac transplantation. " International Journal of Artificial Organs 1991; 14: 276-279.

26. Loebe M, Hennig E, Müller J, Spiegelsberger S, Weng Y, Hetzer R. "Long-term mechanical circulatory support as a bridge to transplantation, for recovery from cardiomyopathy, and for permanent replacement. " European Journal of Cardio-thoracic Surgery 1997; 11(Suppl): S18-S24.

27. Müller J, Wallukat G, Weng YG, Dandel M, Spiegelsberger S, Semrau S, Brandes K, Theodoridis V, Loebe M, Meyer R, Hetzer R. "Weaning from mechanical cardiac support in patients with idiopathic dilated cardiomyopathy. " Circulation 1997; 96: 542-549.

28. Hetzer R, Müller J, Weng Y, Wallukat G, Spiegelsberger S, Loebe M. "Cardiac recovery in dilated cardiomyopathy by unloading with a left ventricular assist device. " Annals of Thoracic Surgery 1999; 68: 742-749.

29 . Loebe M, Müller J, Hetzer R. "Ventricular assistance for recovery of cardiac failure." Current Opinion in Cardiology 1999; 14: 234-248.

30. Oz MC, Argenziano M, Catanese KA, Gardocki MT, Goldstein DJ, Ashton RC, Gelijns AC, Rose EA, Levin HR. "Bridge experience with long-term implantable left ventricular assist devices. Are they an alternative to transplantation?" Circulation 1997; 95: 1844-1852.

31. Kormos RL, Borovetz HS, Gasior T, Antaki JF, Armitage JM, Pristas JM, Hardesty RL, Griffith BP. "Experience with univentricular support in mortally ill cardiac transplant candidates." Annals of Thoracic Surgery 1990; 49: 261-272.


115

32. Frazier OH, Rose EA, Macmanus Q, Burton NA, Lefrak EA, Poirier VL, Dasse KA. "Multicenter clinical evaluation of the HeartMate 1000 IP left ventricular assist device. " Annals of Thoracic Surgery 1992; 53: 1080-1090.

33. Nakatani S, Thomas JD, Savage RM, Vargo RL, Smedira NG, McCarthy PM. "Prediction of right ventricular dysfunction after left ventricular assist device implantation." Circulation 1996; 94(Suppl 2): II-216-II-221.

34. Farrar DJ, Compton PG, Hershon JJ, Fonger JD, Hill JD. "Right heart interaction with the mechanically assisted left heart. " World Journal of Surgery 1985; 9: 89-102.

35. Sato N, Mohri H, Miura M, Watanabe T, Nitta S, Sato S. "Right ventricular failure during clinical use of a left ventricular assist device. " ASAIO Transactions 1989; 35: 550-552.

36. Kormos RL, Gasior T, Antaki J, Armitage JM, Miyamoto Y, Borovetz HS, Hardesty RL, Griffith BP. "Evaluation of right ventricular function during clinical left ventricular assistance. " ASAIO Transactions 1989; 35: 547-550.

37 . Fukamachi K, McCarthy PM, Smedira NG, Vargo RL, Starling RC, Young JB. "Preoperative risk factors for right ventricular failure after implantable left ventricular assist device insertion." Annals of Thoracic Surgery 1999; 68: 2181-2184.

38. Oz MC, Slater JP, Edwards N, Dickstein ML, Beck JR, Spotnitz HM, Levin HR. "Desaturated venous-to-arterial shunting reduces right-sided heart failure after cardiopulmonary bypass." Journal of Heart and Lung Transplantation 1995; 14(Suppl): S172-S176.

39. Moon MR, Castro LJ, DeAnda A, Tomizawa Y, Daughters GT, Ingels NB, Miller DC. "Right ventricular dynamics during left ventricular assistance in closed-chest dogs." Annals of Thoracic Surgery 1993; 56: 54-67.

40. Starr I, Jeffers WA, Meade RH. "The absence of conspicuous increments of venous pressure after severe damage to the right ventricle of the dog, with a discussion of the relation between clinical congestive failure and heart disease." American Heart Journal 1943; 26: 291-301.

41. Kagan A. "Dynamic response of the right ventricle following extensive damage by cauterization. " Circulation 1952; 5: 816-823.

42. Donald DE, Essex HE. "Pressure studies after inactivation of the major portion of the canine right ventricle." American Journal of Physiology 1954; 14: 155-166.


116

43. Jett GK, Applebaum RE, Clark RE. "Right ventricular assistance for experimental right ventricular dysfunction. " Journal of Thoracic and Cardiovascular Surgery 1986; 92: 272-278.

44. Weber KT, Janicki JS, Shroff SG, Likoff MJ, St John Sutton MG. "The right ventricle: physiologic and pathophysiologic considerations." Critical Care Medicine 1983; 11: 323-328.

45. Weber KT, Kinasewitz GT, Janicki JS, Fishman AP. "Oxygen utilization and ventilation during exercise in patients with chronic cardiac failure. " Circulation 1982; 65: 1213-1223.

46. Brooks H, Kirk ES, Vokonas PS, Urschel CW, Sonnenblick EH. "Performance of the right ventricle under stress: relation to right coronary flow." Journal of Clinical Investigation 1971; 50: 2176-2183.

47. Barnard D, Alpert JS. "Right ventricular function in health and disease. " Journal of Clinical Investigation 1987; 12: 417-449.

48. Abel FL, Waldhausen JA. "Effects of alterations in pulmonary vascular resistance on right ventricular function." Journal of Thoracic and Cardiovascular Surgery 1967; 54: 886-894.

49. Sarnoff SJ, Berglund E. "Ventricular function. I. Starling's law of the heart studied by means of simultaneous right and left ventricular function curves in the dog." Circulation 1954; 9: 706-718.

50. Pennington DG, Swartz MT. "Assisted circulation and mechanical hearts." In: Braunwald E, ed. Heart Disease: a textbook of cardiovascular medicine. 4th ed. Philadelphia: Saunders, 1992: 535-550.

51. Farrar DJ, Compton PG, Dajee H, Fonger JD, Hill JD. "Right heart function during left heart assist and the effects of volume loading in a canine preparation." Circulation 1984; 70: 708-716.

52. Miyamoto AT, Tanaka S, Matloff JM. "Right ventricular function during left heart bypass." Journal of Thoracic and Cardiovascular Surgery 1983; 85: 49-53.

53. Chow E, Farrar DJ. "Effects of left ventricular pressure reductions on right ventricular systolic performance. " American Journal of Physiology 1989; 257: H1878-H1885.

54. Fukamachi K, Asou T, Nakamura Y, Toshima Y, Oe M, Mitani A, Sakamoto M, Kishizaki K, Sunagawa K, Tokunaga K. "Effects of left heart bypass on right ventricular performance. Evaluation of the right ventricular end-systolic and end-diastolic pressure-volume relation in the in situ normal canine heart." Journal of Thoracic and Car


117

diovascular Surgery 1990; 99: 725-734.

55. Elbeery JR, Owen CH, Savitt MA, Davis JW, Feneley MP, Rankin JS, VanTrigt P. "Effects of the left ventricular assist device on right ventricular function." Journal of Thoracic and Cardiovascular Surgery 1990; 99: 809-816.

56. Farrar DJ, Compton PG, Hershon JJ, Hill JD. "Right ventricular function in an operating room model of mechanical left ventricular assistance and its effects in patients with depressed left ventricular function. " Circulation 1985; 72: 1279-1285.

57. Morita S, Kormos RL, Eishi K. "Left ventricular assistance improves mechanical efficiency of the right ventricle. " Surgical Forum 1991; 42: 311-314.

58. Morita S, Kormos RL, Mandarino WA, Eishi K, Kawai A, Gasior TA, Deneault LG, Armitage JM, Hardesty RL, Griffith BP. "Right ventricular/arterial coupling in the patient with left ventricular assistance. " Circulation 1992; 86(Suppl 2): II-316-II-325.

59. Moon MR, DeAnda A, Castro LJ, Daughters GT, Ingels NB, Miller DC. "Effects of mechanical left ventricular support on right ventricular diastolic function." Journal of Heart and Lung Transplantation 1997; 16: 398-407.

60. Moon MR, Bolger AF, DeAnda A, Komeda M, Daughters GT, Nikolic SD, Miller DC, Ingels NB. "Septal function during left ventricular unloading. " Circulation 1997; 95: 1320-1327.

61. Hendry PJ, Ascah KJ, Rajagopalan K, Calvin JE. "Does septal position affect right ventricular function during left ventricular assist in an experimental porcine model?" Circulation 1994; 90(Suppl 2): II-353-II-358.

62. Daly RC, Chandrasekaran K, Cavarocchi NC, Tajik AJ, Schaff HV. "Ischemia of the interventricular septum. A mechanism of right ventricular failure during mechanical left ventricular assist." Journal of Thoracic and Cardiovascular Surgery 1992; 103: 1186-1191.

63. Lazar JM, Flores AR, Grandis DJ, Orie JE, Schulman DS. "Effects of chronic right ventricular pressure overload on left ventricular diastolic function." American Journal of Cardiology 1993; 72: 1179-1182.

64. Grossman W. "Clinical measurement of vascular resistance and assessment of vasodilator drugs. " In: Grossman W, Baim DS, eds. Cardiac catheterization, angiography, and intervention. 4th ed. Philadelphia: Lea & Febiger, 1991: 141-151.

65. Harris P, Segel N, Bishop J. "The relationsship between pressure and flow in the pulmonary circulation in normal subjects and in patients with chronic bronchitis and mitral stenosis." Cardiovascular Research 1968; 1: 73-82.


118

66. Charms BL, Brofman BL, Elder JC, Kohn PM. "Unilateral pulmonary artery occlusion in man. II. Studies in patients with chronic pulmonary disease. " Journal of Thoracic Surgery 1958; 35: 316-331.

67. Moraes DL, Colucci WS, Givertz MM. "Secondary pulmonary hypertension in chronic heart failure: the role of the endothelium in pathophysiology and management." Circulation 2000; 102: 1718-1723.

68. Tuder RM, Lee SD, Cool CC. "Histopathology of pulmonary hypertension." Chest 1998; 114(1 Suppl): 1S-6S.

69. Leopore JJ, Bloch KD. "Nitric oxide and pulmonary hypertension." In: Loscalzo J, Vita JA, eds. Nitric oxide and the cardiovascular system. Totowa: Humana Press, 2000: 247-271.

70 Furchgott RF, Zawadzki JV. "The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. " Nature 1980; 288: 373-376.

71. Palmer RM, Ferrige AG, Moncada S. "Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. " Nature 1987; 327: 524-526.

72. Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. "Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. " Proceedings of the National Academy of Sciences of the United States of America 1987; 84: 9265-9269.

73. Feelisch M, Kelm M. "Biotransformation of organic nitrates to nitric oxide by vascular smooth muscle and endothelial cells. " Biochemical and Biophysical Research Communications 1991; 180: 286-293.

74. Moncada S, Higgs A. "The L-arginine-nitric oxide pathway." New England Journal of Medicine 1993; 329: 2002-2012.

75. Nathan C. "Inducible nitric oxide synthase: what difference does it make?" Journal of Clinical Investigation 1997; 100: 2417-2423.

76. Nakane M, Arai K, Saheki S, Kuno T, Buechler W, Murad F. "Molecular cloning and expression of cDNAs coding for soluble guanylate cyclase from rat lung." Journal of Biological Chemistry 1990; 265: 16841-16845.

77. Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB. "Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase. " Journal of Biological Chemistry 1998; 273: 15559-15564.


119

78. Radomski MW, Palmer RM, Moncada S. "An L-arginine/nitric oxide pathway present in human platelets regulates aggregation." Proceedings of the National Academy of Sciences of the United States of America 1990; 87: 5193-5197.

79. Ignarro LJ, Byrns RE, Buga GM, Wood KS. "Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical. " Circulation Research 1987; 61: 866-879.

80. Ignarro LJ, Buga GM, Chaudhuri G. "EDRF generation and release from perfused bovine pulmonary artery and vein. " European Journal of Pharmacology 1988; 149: 79-88.

81. Cremona G, Dinh-Xuan AT, Higenbottam TW. "Endothelium-derived relaxing factor and the pulmonary circulation." Lung 1991; 169: 185-202.

82. Dinh-Xuan AT. "Endothelial modulation of pulmonary vascular tone. " European Respiratory Journal 1992; 5: 757-762.

83. McMahon TJ, Hood JS, Bellan JA, Kadowitz PJ. "N omega-nitro-L-arginine methyl ester selectively inhibits pulmonary vasodilator responses to acetylcholine and bradykinin. " Journal of Applied Physiology 1991; 71: 2026-2031.

84. Stamler JS, Loh E, Roddy MA, Currie KE, Creager MA. "Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans. " Circulation 1994; 89: 2035-2040.

85. Blitzer ML, Loh E, Roddy MA, Stamler JS, Creager MA. "Endothelium-derived nitric oxide regulates systemic and pulmonary vascular resistance during acute hypoxia in humans. " Journal of the American College of Cardiology 1996; 28: 591-596 .

86: Cooper CJ, Landzberg MJ, Anderson TJ, Charbonneau F, Creager MA, Ganz P, Selwyn AP. "Role of nitric oxide in the local regulation of pulmonary vascular resistance in humans. " Circulation 1996; 93: 266-271.

87. Ontkean M, Gay R, Greenberg B. "Diminished endothelium-derived relaxing factor activity in an experimental model of chronic heart failure. " Circulation Research 1991; 69: 1088-1096.

88. Cooper CJ, Jevnikar FW, Walsh T, Dickinson J, Mouhaffel A, Selwyn AP. "The influence of basal nitric oxide activity on pulmonary vascular resistance in patients with congestive heart failure. " American Journal of Cardiology 1998; 82: 609-614.

89. Leier CV, Huss P, Magorien RD, Unverferth DV. "Improved exercise capacity and differing arterial and venous tolerance during chronic isosorbide dinitrate therapy for congestive heart failure." Circulation 1983; 67: 817-822.


120

90. Rimar S, Gillis CN. "Selective pulmonary vasodilation by inhaled nitric oxide is due to hemoglobin inactivation. " Circulation 1993; 88: 2884-2887.

91. Frostell CG, Blomqvist H, Hedenstierna G, Lundberg J, Zapol WM. "Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation." Anesthesiology 1993; 78: 427-435.

92. Moinard J, Manier G, Pillet O, Castaing Y. "Effect of inhaled nitric oxide on hemodynamics and VA/Q inequalities in patients with chronic obstructive pulmonary disease." American Journal of Respiratory and Critical Care Medicine 1994; 149: 1482-1487.

93. Rossaint R, Falke KJ, Lopez F, Slama K, Pison U, Zapol WM. "Inhaled nitric oxide for the adult respiratory distress syndrome. " New England Journal of Medicine 1993; 328: 399-405.

94. Roberts JD, Polaner DM, Lang P, Zapol WM. "Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. " Lancet 1992; 340: 818-819.

95. Roberts JD, Fineman JR, Morin FC, Shaul PW, Rimar S, Schreiber MD, Polin RA, Zwass MS, Zayek MM, Gross I, Heymann MA, Zapol WM. "Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group. " New England Journal of Medicine 1997; 336: 605-610.

96. The Neonatal Inhaled Nitric Oxide Study Group. "Inhaled nitric oxide in full-term and nearly full-term infants with hypoxic respiratory failure. " New England Journal of Medicine 1997; 336: 597-604.

97. Yoshida M, Taguchi O, Gabazza EC, Yasui H, Kobayashi T, Kobayashi H, Maruyama K, Adachi Y. "The effect of low-dose inhalation of nitric oxide in patients with pulmonary fibrosis. " European Respiratory Journal 1997; 10: 2051-2054.

98. Williamson DJ, Hayward C, Rogers P, Wallman LL, Sturgess AD, Penny R, Macdonald PS. "Acute hemodynamic responses to inhaled nitric oxide in patients with limited scleroderma and isolated pulmonary hypertension. " Circulation 1996; 94: 477-482.

99. Scherrer U, Vollenweider L, Delabays A, Savcic M, Eichenberger U, Kleger GR, Fikrle A, Ballmer PE, Nicod P, Bartsch P. "Inhaled nitric oxide for high-altitude pulmonary edema. " New England Journal of Medicine 1996; 334: 624-629.

100. Pepke-Zaba J, Higenbottam TW, Dinh-Xuan AT, Stone D, Wallwork J. "Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension." Lancet 1991; 338: 1173-1174.

101. Roberts JD, Lang P, Bigatello LM, Vlahakes GJ, Zapol WM. "Inhaled nitric oxide in congenital heart disease. " Circulation 1993; 87: 447-453.


121

102. Girard C, Lehot JJ, Pannetier JC, Filley S, Ffrench P, Estanove S. "Inhaled nitric oxide after mitral valve replacement in patients with chronic pulmonary artery hypertension. " Anesthesiology 1992; 77: 880-883.

103. Adatia I, Perry S, Landzberg M, Moore P, Thompson JE, Wessel DL. "Inhaled nitric oxide and hemodynamic evaluation of patients with pulmonary hypertension before transplantation." Journal of the American College of Cardiology 1995; 25: 1656-1664.

104. Semigran MJ, Cockrill BA, Kacmarek R, Thompson BT, Zapol WM, Dec GW, Fifer MA. "Hemodynamic effects of inhaled nitric oxide in heart failure. " Journal of the American College of Cardiology 1994; 24: 982-988.

105. Loh E, Stamler JS, Hare JM, Loscalzo J, Colucci WS. "Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction. " Circulation 1994; 90: 2780-2785.

106. Hare JM, Shernan SK, Body SC, Graydon E, Colucci WS, Couper GS. "Influence of inhaled nitric oxide on systemic flow and ventricular filling pressure in patients receiving mechanical circulatory assistance." Circulation 1997; 95: 2250-2253.

107. Hess D, Bigatello L, Hurford WE. "Toxicity and complications of inhaled nitric oxide." Respiratory Care Clinics of North America 1997; 3: 487-503.

108. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. "A novel potent vasoconstrictor peptide produced by vascular endothelial cells. " Nature 1988; 332: 411-415.

109. Ohnaka K, Takayanagi R, Yamauchi T, Okazaki H, Ohashi M, Umeda F, Nawata H. "Identification and characterization of endothelin converting activity in cultured bovine endothelial cells." Biochemical and Biophysical Research Communications 1990; 168: 1128-1136.

110. Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T, Goto K, Masaki T. "The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes." Proceedings of the National Academy of Sciences of the United States of America 1989; 86: 2863-2867.

111. Fukuroda T, Kobayashi M, Ozaki S, Yano M, Miyauchi T, Onizuka M, Sugishita Y, Goto K, Nishikibe M. "Endothelin receptor subtypes in human versus rabbit pulmonary arteries." Journal of Applied Physiology 1994; 76: 1976-1982.

112. Zellers TM, McCormick J, Wu Y. "Interaction among ET-1, endothelium-derived nitric oxide, and prostacyclin in pulmonary arteries and veins." American Journal of Physiology 1994; 267: H139-H147.


122

113. Stewart DJ, Levy RD, Cernacek P, Langleben D. "Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? " Annals of Internal Medicine 1991; 114: 464-469.

114. Cody RJ, Haas GJ, Binkley PF, Capers Q, Kelley R. "Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure." Circulation 1992; 85: 504-509.

115. Dupuis J, Stewart DJ, Cernacek P, Gosselin G. "Human pulmonary circulation is an important site for both clearance and production of endothelin-1." Circulation 1996; 94: 1578-1584.

116. Tsutamoto T, Wada A, Maeda Y, Adachi T, Kinoshita M. "Relation between endothelin-1 spillover in the lungs and pulmonary vascular resistance in patients with chronic heart failure. " Journal of the American College of Cardiology 1994; 23: 1427-1433.

117. Giaid A, Yanagisawa M, Langleben D, Michel RP, Levy R, Shennib H, Kimura S, Masaki T, Duguid WP, Stewart DJ. "Expression of endothelin-1 in the lungs of patients with pulmonary hypertension." New England Journal of Medicine 1993; 328: 1732-1739.

118. Zolk O, Quattek J, Sitzler G, Schrader T, Nickenig G, Schnabel P, Shimada K, Takahashi M, Bohm M. "Expression of endothelin-1, endothelin-converting enzyme, and endothelin receptors in chronic heart failure." Circulation 1999; 99: 2118-2123.

119. Wei CM, Lerman A, Rodeheffer RJ, McGregor CG, Brandt RR, Wright S, Heublein DM, Kao PC, Edwards WD, Burnett JC. "Endothelin in human congestive heart failure." Circulation 1994; 89: 1580-1586.

120. Kiowski W, Sutsch G, Hunziker P, Muller P, Kim J, Oechslin E, Schmitt R, Jones R, Bertel O. "Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. " Lancet 1995; 346: 732-736.

121. Benigni A, Remuzzi G. "Endothelin antagonists." Lancet 1999; 353: 133-138.

122. Lippton HL, Hauth TA, Summer WR, Hyman AL. "Endothelin produces pulmonary vasoconstriction and systemic vasodilation. " Journal of Applied Physiology 1989; 66: 1008-1012.

123. Buchan KW, Magnusson H, Rabe KF, Sumner MJ, Watts IS. "Characterisation of the endothelin receptor mediating contraction of human pulmonary artery using BQ123 and Ro 46-2005. " European Journal of Pharmacology 1994; 260: 221-226.


123

124. Picard P, Smith PJ, Monge JC, Rouleau JL, Nguyen QT, Calderone A, Stewart DJ. "Coordinated upregulation of the cardiac endothelin system in a rat model of heart failure. " Journal of Cardiovascular Pharmacology 1998; 31(Suppl 1): S294-S297.

125. Guarda E, Katwa LC, Myers PR, Tyagi SC, Weber KT. "Effects of endothelins on collagen turnover in cardiac fibroblasts. " Cardiovascular Research 1993; 27: 2130-2134.

126. Zamora MA, Dempsey EC, Walchak SJ, Stelzner TJ. "BQ123, an ETA receptor antagonist, inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells." American Journal of Respiratory Cell and Molecular Biology 1993; 9: 429-433.

127. Böttiger BW, Rauch H, Bohrer H, Motsch J, Soder M, Fleischer F, Martin E. "Continuous versus intermittent cardiac output measurement in cardiac surgical patients undergoing hypothermic cardiopulmonary bypass. " Journal of Cardiothoracic and Vascular Anesthesia 1995; 9: 405-411.

128. Boldt J, Menges T, Wollbruck M, Hammermann H, Hempelmann G. "Is continuous cardiac output measurement using thermodilution reliable in the critically ill patient? " Critical Care Medicine 1994; 22: 1913-1918.

129. Francoe M, Troncy E, Blaise G. "Inhaled nitric oxide: technical aspects of administration and monitoring. " Critical Care Medicine 1998; 26: 782-796.

130. Feigenbaum H. Echocardiography. 5th ed. Philadelphia: Lea & Febiger, 1994: 134-180.

131. Jiang L, Wiegers SE, Weyman AE. "Right ventricle." In: Weyman AE, ed. Principles and practice of echocardiography. 2nd ed. Philadelphia: Lea & Febiger, 1994: 901-921.

132. Kovach JA, Minz GS. "Assessment of right ventricular function. " In: St. John Sutton MG, Oldershaw PJ, Kotler NM, eds. Textbook of echocardiography and Doppler in adults and children. Cambridge: Blackwell Science, 1996: 97-115.

133. Jiang L, Levine RA, Weyman AE. "Echocardiographic Assessment of Right Ventricular Volume and Function. " Echocardiography 1997; 14: 189-206.

134. Jiang L, Handschumacher MD, Hibberd MG, Siu SC, King ME, Weyman AE, Levine RA. "Three-dimensional echocardiographic reconstruction of right ventricular volume: in vitro comparison with two-dimensional methods." Journal of the American Society of Echocardiography 1994; 7: 150-158.


124

135. Oe M, Gorcsan J, Mandarino WA, Kawai A, Griffith BP, Kormos RL. "Automated echocardiographic measures of right ventricular area as an index of volume and end-systolic pressure-area relations to assess right ventricular function." Circulation 1995; 92: 1026-1033.

136. Lindberg L, Rydgren G, Larsson A, Olsson SG, Nordstrom L. "A delivery system for inhalation of nitric oxide evaluated with chemiluminescence, electrochemical fuel cells, and capnography. " Critical Care Medicine 1997; 25: 190-196.

137. Schocken DD, Arrieta MI, Leaverton PE, Ross EA. "Prevalence and mortality rate of congestive heart failure in the United States. " Journal of the American College of Cardiology 1992; 20: 301-306.

138. Kriett JM, Kaye MP. "The Registry of the International Society for Heart and Lung Transplantation: eighth official report - 1991." Journal of Heart and Lung Transplantation 1991; 10: 491-498.

139. Franciosa JA, Wilen M, Ziesche S, Cohn JN. "Survival in men with severe chronic left ventricular failure due to either coronary heart disease or idiopathic dilated cardiomyopathy. " American Journal of Cardiology 1983; 51: 831-836.

140. Stevenson LW. "Inotropic therapy for heart failure." New England Journal of Medicine 1998; 339: 1848-1850.

141. Persijn G, Cohen B, eds. Eurotransplant Foundation: annual report. Leiden: Eurotransplant Foundation, 1995.

142. McManus RP, O'Hair DP, Beitzinger JM, Schweiger J, Siegel R, Breen TJ, Olinger GN. "Patients who die awaiting heart transplantation." Journal of Heart and Lung Transplantation 1993; 12: 159-172.

143. Goldstein DJ, Oz MC, Rose EA. "Implantable left ventricular assist devices." New England Journal of Medicine 1998; 339: 1522-1533.

144. Hunt SA, Frazier OH. "Mechanical circulatory support and cardiac transplantation." Circulation 1998; 97: 2079-2090.

145. Frazier OH, Rose EA, McCarthy P, Burton NA, Tector A, Levin H, Kayne HL, Poirier VL, Dasse KA. "Improved mortality and rehabilitation of transplant candidates treated with a long-term implantable left ventricular assist system." Annals of Surgery 1995; 222: 327-338.

146. Goldstein DJ, Seldomridge JA, Chen JM, Catanese KA, DeRosa CM, Weinberg AD, Smith CR, Rose EA, Levin HR, Oz MC. "Use of aprotinin in LVAD recipients reduces blood loss, blood use, and perioperative mortality." Annals of Thoracic Surgery


125

1995; 59: 1063-1068.

147. Kormos RL, Borovetz HS, Armitage JM, Hardesty RL, Marrone GC, Griffith BP. "Evolving experience with mechanical circulatory support." Annals of Surgery 1991; 214: 471-477.

148. Cave AC, Manche A, Derias NW, Hearse DJ. "Thromboxane A2 mediates pulmonary hypertension after cardiopulmonary bypass in the rabbit. " Journal of Thoracic and Cardiovascular Surgery 1993; 106: 959-967.

149. Fullerton DA, McIntyre RC. "Inhaled nitric oxide: therapeutic applications in cardiothoracic surgery." Annals of Thoracic Surgery 1996; 61: 1856-1864.

150. Wessel DL, Adatia I, Giglia TM, Thompson JE, Kulik TJ. "Use of inhaled nitric oxide and acetylcholine in the evaluation of pulmonary hypertension and endothelial function after cardiopulmonary bypass. " Circulation 1993; 88: 2128-2138.

151. Fullerton DA, Mitchell MB, Jones DN, Maki A, McIntyre RC. "Pulmonary vasomotor dysfunction is produced with chronically high pulmonary blood flow. " Journal of Thoracic and Cardiovascular Surgery 1996; 111: 190-197.

152. Wessel DL. "Inhaled nitric oxide for the treatment of pulmonary hypertension before and after cardiopulmonary bypass." Critical Care Medicine 1993; 21(9 Suppl): S344-S345.

153. Farrar DJ, Chow E, Compton PG, Foppiano L, Woodard J, Hill JD. "Effects of acute right ventricular ischemia on ventricular interactions during prosthetic left ventricular support." Journal of Thoracic and Cardiovascular Surgery 1991; 102: 588-595.

154. Waldenberger F, Kim YI, Laycock S, Meyns B, Flameng W. "Effects of failure of the right side of the heart and increased pulmonary resistance on mechanical circulatory support with use of the miniaturized HIA-VAD displacement pump system. " Journal of Thoracic and Cardiovascular Surgery 1996; 112: 484-493.

155. Bigatello LM, Hurford WE, Kacmarek RM, Roberts JD, Zapol WM. "Prolonged inhalation of low concentrations of nitric oxide in patients with severe adult respiratory distress syndrome. Effects on pulmonary hemodynamics and oxygenation. " Anesthesiology 1994; 80: 761-770.

156. Kadowitz PJ, Nandiwada P, Gruetter CA, Ignarro LJ, Hyman AL. "Pulmonary vasodilator responses to nitroprusside and nitroglycerin in the dog." Journal of Clinical Investigation 1981; 67: 893-902.


126

157. Sibbald WJ, Driedger AA, McCallum D, Cunningham D, Cheung H. "Nitroprusside infusion does not improve biventricular performance in patients with acute hypoxaemic respiratory failure." J Crit Care 1986; 1: 197-203.

158. Radermacher P, Santak B, Assmann R, Falke KJ. "Prostaglandin E1 and right ventricular function in ARDS. " Intensive Care Medicine 1989; 15: 146-147.

159. Pascual JM, Fiorelli AI, Bellotti GM, Stolf NA, Jatene AD. "Prostacyclin in the management of pulmonary hypertension after heart transplantation." Journal of Heart and Lung Transplantation 1990; 9: 644-651.

160. Rajek A, Pernerstorfer T, Kastner J, Mares P, Grabenwoger M, Sessler DI, Grubhofer G, Hiesmayr M. "Inhaled nitric oxide reduces pulmonary vascular resistance more than prostaglandin E(1) during heart transplantation. " Anesthesia and Analgesia 2000; 90: 523-530.

161. Califf RM, Adams KF, McKenna WJ, Gheorghiade M, Uretsky BF, McNulty SE, Darius H, Schulman K, Zannad F, Handberg-Thurmond E, Harrell FE, Wheeler W, Soler-Soler J, Swedberg K. "A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST). " American Heart Journal 1997; 134: 44-54.

162. Kieler-Jensen N, Ricksten SE, Stenqvist O, Bergh CH, Lindelov B, Wennmalm A, Waagstein F, Lundin S. "Inhaled nitric oxide in the evaluation of heart transplant candidates with elevated pulmonary vascular resistance. " Journal of Heart and Lung Transplantation 1994; 13: 366-375.

163. Rich GF, Murphy GD, Roos CM, Johns RA. "Inhaled nitric oxide. Selective pulmonary vasodilation in cardiac surgical patients. " Anesthesiology 1993; 78: 1028-1035.

164. Kieler-Jensen N, Lundin S, Ricksten SE. "Vasodilator therapy after heart transplantation: effects of inhaled nitric oxide and intravenous prostacyclin, prostaglandin E1, and sodium nitroprusside." Journal of Heart and Lung Transplantation 1995; 14: 436-443.

165. Fullerton DA, Jaggers J, Wollmering MM, Piedalue F, Grover FL, McIntyre RC. "Variable response to inhaled nitric oxide after cardiac surgery." Annals of Thoracic Surgery 1997; 63: 1251-1256.

166. Krasuski RA, Warner JJ, Wang A, Harrison JK, Tapson VF, Bashore TM. "Inhaled nitric oxide selectively dilates pulmonary vasculature in adult patients with pulmonary hypertension, irrespective of etiology." Journal of the American College of Cardiology 2000; 36: 2204-2211.


127

167. Rossaint R, Slama K, Steudel W, Gerlach H, Pappert D, Veit S, Falke K. "Effects of inhaled nitric oxide on right ventricular function in severe acute respiratory distress syndrome. " Intensive Care Medicine 1995; 21: 197-203.

168. Bhorade S, Christenson J, O'Connor M, Lavoie A, Pohlman A, Hall JB. "Response to inhaled nitric oxide in patients with acute right heart syndrome." American Journal of Respiratory and Critical Care Medicine 1999; 159: 571-579.

169. Girard C, Durand PG, Vedrinne C, Pannetier JC, Estanove S, Falke K, Adnot S, Lemaire F. "Case 4-1993. Inhaled nitric oxide for right ventricular failure after heart transplantation." Journal of Cardiothoracic and Vascular Anesthesia 1993; 7: 481-485.

170. Argenziano M, Choudhri AF, Moazami N, Rose EA, Smith CR, Levin HR, Smerling AJ, Oz MC. "Randomized, double-blind trial of inhaled nitric oxide in LVAD recipients with pulmonary hypertension. " Annals of Thoracic Surgery 1998; 65: 340-345.

171. Demirakca S, Dotsch J, Knothe C, Magsaam J, Reiter HL, Bauer J, Kuehl PG. "Inhaled nitric oxide in neonatal and pediatric acute respiratory distress syndrome: dose response, prolonged inhalation, and weaning. " Critical Care Medicine 1996; 24: 1913-1919.

172. Manktelow C, Bigatello LM, Hess D, Hurford WE. "Physiologic determinants of the response to inhaled nitric oxide in patients with acute respiratory distress syndrome." Anesthesiology 1997; 87: 297-307.

173 . Dellinger RP, Zimmerman JL, Taylor RW, Straube RC, Hauser DL, Criner GJ, Davis K, Jr., Hyers TM, Papadakos P. "Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome: results of a randomized phase II trial. Inhaled Nitric Oxide in ARDS Study Group." Critical Care Medicine 1998; 26: 15-23.

174. Nakajima W, Ishida A, Arai H, Takada G. "Methaemoglobinaemia after inhalation of nitric oxide in infant with pulmonary hypertension. " Lancet 1997; 350: 1002-1003.

175. Wessel DL, Adatia I, Thompson JE, Hickey PR. "Delivery and monitoring of inhaled nitric oxide in patients with pulmonary hypertension." Critical Care Medicine 1994; 22: 930-938.

176. Nishimura M, Hess D, Kacmarek RM, Ritz R, Hurford WE. "Nitrogen dioxide production during mechanical ventilation with nitric oxide in adults. Effects of ventilator internal volume, air versus nitrogen dilution, minute ventilation, and inspired oxygen fraction." Anesthesiology 1995; 82: 1246-1254.

177. Hogman M, Frostell C, Arnberg H, Hedenstierna G. "Bleeding time prolongation and NO inhalation." Lancet 1993; 341: 1664-1665 .


128

178. Samama CM, Diaby M, Fellahi JL, Mdhafar A, Eyraud D, Arock M, Guillosson JJ, Coriat P, Rouby JJ. "Inhibition of platelet aggregation by inhaled nitric oxide in patients with acute respiratory distress syndrome." Anesthesiology 1995; 83: 56-65.

179. Lavoie A, Hall JB, Olson DM, Wylam ME. "Life-threatening effects of discontinuing inhaled nitric oxide in severe respiratory failure. " American Journal of Respiratory and Critical Care Medicine 1996; 153: 1985-1987.

180. Christenson J, Lavoie A, O'Connor M, Bhorade S, Pohlman A, Hall JB. "The incidence and pathogenesis of cardiopulmonary deterioration after abrupt withdrawal of inhaled nitric oxide. " American Journal of Respiratory and Critical Care Medicine 2000; 161: 1443-1449.

181. Wink DA, Kasprzak KS, Maragos CM, Elespuru RK, Misra M, Dunams TM, Cebula TA, Koch WH, Andrews AW, Allen JS, et al. "DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. " Science 1991; 254: 1001-1003.

182. Oda H, Nogami H, Kusumoto S, Nakujima T, Kurata A, Imai K. "Long-term exposure to nitric oxide in mice." Journal of Japan Society of Air Pollution 1976; 11: 150-160.

183. The National Institute for Occupational Safety and Health. "NIOSH recommendations for occupational safety and health standards 1988. MMWR." Morbidity and mortality weekly report 1988; 37: 1-29.

184. Cuthbertson BH, Dellinger P, Dyar OJ, Evans TE, Higenbottam T, Latimer R, Payen D, Stott SA, Webster NR, Young JD. "UK guidelines for the use of inhaled nitric oxide therapy in adult ICUs. American-European Consensus Conference on ALI/ARDS." Intensive Care Medicine 1997; 23: 1212-1218.

185. Imanaka H, Hess D, Kirmse M, Bigatello LM, Kacmarek RM, Steudel W, Hurford WE. "Inaccuracies of nitric oxide delivery systems during adult mechanical ventilation. " Anesthesiology 1997; 86: 676-688.

186. Beloucif S, Payen D. "A European survey of the use of inhaled nitric oxide in the ICU. Working Group on Inhaled NO in the ICU of the European Society of Intensive Care Medicine. " Intensive Care Medicine 1998; 24: 864-877.

187. Damiano RJ, La Follette P, Cox JL, Lowe JE, Santamore WP. "Significant left ventricular contribution to right ventricular systolic function." American Journal of Physiology 1991; 261: H1514-H1524.

188. Brinker JA, Weiss JL, Lappe DL, Rabson JL, Summer WR, Permutt S, Weisfeldt ML. "Leftward septal displacement during right ventricular loading in man. " Circulation 1980; 61: 626-633.


129

189. Boulanger C, Luscher TF. "Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. " Journal of Clinical Investigation 1990; 85: 587-590.

190. Warner TD, Mitchell JA, de Nucci G, Vane JR. "Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit." Journal of Cardiovascular Pharmacology 1989; 13(Suppl 5): S85-S88.

191 . Komai H, Adatia IT, Elliott MJ, de Leval MR, Haworth SG. "Increased plasma levels of endothelin-1 after cardiopulmonary bypass in patients with pulmonary hypertension and congenital heart disease." Journal of Thoracic and Cardiovascular Surgery 1993; 106: 473-478.

192. Saijonmaa O, Ristimaki A, Fyhrquist F. "Atrial natriuretic peptide, nitroglycerine, and nitroprusside reduce basal and stimulated endothelin production from cultured endothelial cells. " Biochemical and Biophysical Research Communications 1990; 173: 514-520.

193. Yokokawa K, Kohno M, Yasunari K, Murakawa K, Takeda T. "Endothelin-3 regulates endothelin-1 production in cultured human endothelial cells." Hypertension 1991; 18: 304-315.

194. Ahlborg G, Lundberg JM. "Nitric oxide-endothelin-1 interaction in humans." Journal of Applied Physiology 1997; 82: 1593-1600.

195. Stangl K, Dschietzig T, Richter C, Laule M, Stangl V, Tanis E, Baumann G, Felix SB. "Pulmonary release and coronary and peripheral consumption of big endothelin and endothelin-1 in severe heart failure: acute effects of vasodilator therapy." Circulation 2000; 102: 1132-1138.

196. Dupuis J, Cernacek P, Tardif JC, Stewart DJ, Gosselin G, Dyrda I, Bonan R, Crepeau J. "Reduced pulmonary clearance of endothelin-1 in pulmonary hypertension." American Heart Journal 1998; 135: 614-620.

197. Kirklin JK, Westaby S, Blackstone EH, Kirklin JW, Chenoweth DE, Pacifico AD. "Complement and the damaging effects of cardiopulmonary bypass. " Journal of Thoracic and Cardiovascular Surgery 1983; 86: 845-857.

198. Komai H, Yamamoto F, Tanaka K, Murashita T, Shibata T, Sakai H, Kawashima Y. "Increased lung injury in pulmonary hypertensive patients during open heart operations." Annals of Thoracic Surgery 1993; 55: 1147-1152.

199. Kirklin JK. "Prospects for understanding and eliminating the deleterious effects of cardiopulmonary bypass." Annals of Thoracic Surgery 1991; 51: 529-531.


130

200. Kirshbom PM, Jacobs MT, Tsui SS, DiBernardo LR, Schwinn DA, Ungerleider RM, Gaynor JW. "Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung." Journal of Thoracic and Cardiovascular Surgery 1996; 111: 1248-1256.

201. Morita K, Ihnken K, Buckberg GD, Sherman MP, Ignarro LJ. "Pulmonary vasoconstriction due to impaired nitric oxide production after cardiopulmonary bypass." Annals of Thoracic Surgery 1996; 61: 1775-1780.

202. Brett SJ, Quinlan GJ, Mitchell J, Pepper JR, Evans TW. "Production of nitric oxide during surgery involving cardiopulmonary bypass. " Critical Care Medicine 1998; 26: 272-278.

203. Hiramatsu T, Imai Y, Takanashi Y, Hoshino S, Yashima M, Tanaka SA, Chang D, Nakazawa M. "Time course of endothelin-1 and nitrate anion levels after cardiopulmonary bypass in congenital heart defects. " Annals of Thoracic Surgery 1997; 63: 648-652.

204. McMullan DM, Bekker JM, Parry AJ, Johengen MJ, Kon A, Heidersbach RS, Black SM, Fineman JR. "Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow." Circulation 2000; 102(Suppl 3): III-172-III-178.

205. Hynynen M, Saijonmaa O, Tikkanen I, Heinonen J, Fyhrquist F. "Increased plasma endothelin immunoreactivity during cardiopulmonary bypass: a preliminary observation." Journal of Thoracic and Cardiovascular Surgery 1992; 103: 1024-1025.

206. Zhu ZG, Wang MS, Jiang ZB, Jiang Z, Xu SX, Ren CY, Shi MX. "The dynamic change of plasma endothelin-1 during the perioperative period in patients with rheumatic valvular disease and secondary pulmonary hypertension." Journal of Thoracic and Cardiovascular Surgery 1994; 108: 960-968.

207. McMurray JJ, Ray SG, Abdullah I, Dargie HJ, Morton JJ. "Plasma endothelin in chronic heart failure." Circulation 1992; 85: 1374-1379.

208. Dupuis J, Goresky CA, Stewart DJ. "Pulmonary removal and production of endothelin in the anesthetized dog. " Journal of Applied Physiology 1994; 76: 694-700.

209. Dupuis J, Goresky CA, Fournier A. "Pulmonary clearance of circulating endothelin-1 in dogs in vivo: exclusive role of ETB receptors." Journal of Applied Physiology 1996; 81: 1510-1515.


131

210. Dupuis J, Rouleau JL, Cernacek P. "Reduced pulmonary clearance of endothelin-1 contributes to the increase of circulating levels in heart failure secondary to myocardial infarction. " Circulation 1998; 98: 1684-1687.

211. Fukuroda T, Fujikawa T, Ozaki S, Ishikawa K, Yano M, Nishikibe M. "Clearance of circulating endothelin-1 by ETB receptors in rats. " Biochemical and Biophysical Research Communications 1994; 199: 1461-1465.

212. Kobayshi T, Miyauchi T, Sakai S, Maeda S, Yamaguchi I, Goto K, Sugishita Y. "Down-regulation of ET(B) receptor, but not ET(A) receptor, in congestive lung secondary to heart failure. Are marked increases in circulating endothelin-1 partly attributable to decreases in lung ET(B) receptor-mediated clearance of endothelin-1? " Life Sciences 1998; 62: 185-193.

213. Eddahibi S, Raffestin B, Braquet P, Chabrier PE, Adnot S. "Pulmonary vascular reactivity to endothelin-1 in normal and chronically pulmonary hypertensive rats." Journal of Cardiovascular Pharmacology 1991; 17: S358-S361.

214. Fagan JM, Rex SE, Hayes-Licitra SA, Waxman L. "L-arginine reduces right heart hypertrophy in hypoxia-induced pulmonary hypertension." Biochemical and Biophysical Research Communications 1999; 254: 100-103.

215. Kourembanas S, McQuillan LP, Leung GK, Faller DV. "Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia. " Journal of Clinical Investigation 1993; 92: 99-104.


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