[Seite 37↓]

Literaturverzeichnis

1. Taylor ML, Metcalfe DD (2001): Mast cells in allergy and host defense Allergy Asthma Proc 22: 115-9

2. Weber S, Krüger-Krasagakes S, Grabbe J, Zuberbier T, Czarnetzki BM (1995) Mast cells. Int J Dermatol 34: 1-10

3. Artuc M, Hermes B, Steckelings MU, Grützkau A, Henz BM (1999) Mast cells and their mediators in wound healing - active participants or innocent bystanders? Exp Dermatol 8: 1-16

4. Metcalfe DD, Baram D, Mekori YA (1997) Mast cells. Physiol Rev 77, 1033

5. Czarnetzki BM, Grabbe J, Kolde G, Krüger-Krasagakes S, Welker P , Zuberbier T (1995) Mast cells in the cytokine network: The what, where from and what for. Exp. Dermatol. 4: 221-226

6. Haas N, Toppe E, Henz BM (1998) Microscopic morphology of different types of urticaria Arch Dermatol 1998: 134: 41-6

7. Jeziorska M, McCollum C, Woolley DE. (1997) Mast cell distribution, activation, and phenotype in atherosclerotic lesions of human carotid arteries. J Pathol 182 : 115-22

8. Grabbe J, Haas N, Czarnetzki BM (1994) The mast cell. Hautarzt 45: 55-63

9. Benyon RC.Clin Mast cells in the liver (1999) Exp Allergy 29: 155-8

10. Marone G, Patella V, de Crescenzo G, Granata F, Calabrese C. (2000) Immunological interactions between human eosinophils and cardiac mast cells. Chem Immunol 76: 118-33

11. Kurusu A, Suzuki Y, Horikoshi S, Shirato I, Tomino Y. (2001) Relationship between mast cells in the tubulointerstitium and prognosis of patients with IgA nephropathy. Nephron 89: 391-7

12. Panula P, Lintunen M, Karlstedt K. (2000) Histamine in brain development and tumors. Semin Cancer Biol 10: 11-4

13. Purcell WM, Westgate C, Atterwill CK (1996) Rat brain mast cells. An in vitro paradigm for assessing the toxic effects of therapeutics. Neurotoxicology 17: 845-50


[Seite 38↓]

14. Moller A, Henz BM, Grutzkau A, Lippert U, Aragane Y, Schwarz T, Kruger-Krasagakes S. (1998) Comparative cytokine gene expression: regulation and release by human mast cells. Immunology 93: 289-95

15. Horigome K, Pryor JC, Bullock ED, Johnson EM jr (1993) Mediator release from mast cells by nerve growth factor. Neurothrophin specificity and receptor mediation. J Biol Chem 268: 14881-7

16. Chiappara G, Gagliardo R, Siena A, Bonsignore MR, Bousquet J, Bonsignore G, Vignola AM (2001) Airway remodelling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol 1: 85-93

17. Ribatti D, Vacca A, Nico B, Crivellato E, Roncali L, Dammacco F. (2001) The role of mast cells in tumour angiogenesis. Br J Haematol 115: 514-21

18. Bradding P, Holgate ST. Immunopathology and human mast cell cytokines (1999) Crit Rev Oncol Hematol 31: 119-33

19. Kondo S, Kagami S, Kido H, Strutz F, Muller GA, Kuroda Y. (2001) Role of mast cell tryptase in renal interstitial fibrosis J Am Soc Nephrol 12: 1668-76

20. Frangogiannis NG, Smith CW, Entman ML. (2002) The inflammatory response in myocardial infarction Cardiovasc Res 53: 31-47

21. Kruger PG. (2001) Mast cells and multiple sclerosis: a quantitative analysis .Neuropathol Appl Neurobiol 27: 275-80

22. McNeil HP, Gotis-Graham I. (2000) Human mast cell subsets--distinct functions in inflammation? Inflamm Res 49: 3-7

23. .Galli SJ, Wedemeyer J, Tsai M. (2002) Analyzing the roles of mast cells and basophils in host defense and other biological responses. Int J Hematol 75: 363-9

24. Kirshenbaum AS, Goff JP, Kessler SW, Mican JM, Zsebo KM, Metcalf DD (1992) Effect of IL-3 and stem cell factor on the appearance of human basophils and mast cells from CD34+ and pluripotent progenitor cells. J. Immunol. 148: 772-779

25. Czarnetzki BM, Figdor CG, Kolde G, Vroom T, Aalberse R ,de Vries JE (1984) Development of human connective tissue mast cells from purified blood monocytes. Immunology 51: 549-55

26. Du T, Friend DS, Austen KF, Katz HR. (1996) Tissue-dependent differences in the asynchronous appearance of mast cells in normal mice and in congenic mast cell-deficient mice after infusion of normal bone marrow cells. Clin Exp Immunol 103: 316-21


[Seite 39↓]

27. Grizzi F, Franceschini B, Barbieri B, Gagliano N, Arosio B, Chiriva-Internati M, Annoni G, Dioguardi N. (2002) Mast cell density: a quantitative index of acute liver inflammation. Anal Quant Cytol Histol 24: 63-9

28. Inoue T, Yoneda K, Kakurai M, Fujita S, Manabe M, Demitsu T.J (2002) Alteration of mast cell proliferation/apoptosis and expression of stem cell factor in the regression of mastocytoma - report of a case and a serial immunohistochemical study. Cutan Pathol 29: 305-12

29. Ashman LK. (1999) The biology of stem cell factor and its receptor C-kit. Int J Biochem Cell Biol 311: 1037-51

30. Matsuda H, Kannan Y, Ushio H, Kiso Y, Kanemoto T, Suzuki H, Kitamura Y.J (1991) Nerve growth factor induces development of connective tissue-type mast cells in vitro from murine bone marrow cells. Exp Med 174: 7-14

31. Lantz CS, Huff TF (1995) Differential responsiveness of purified mouse c-kit+ mast cells and their progenitors to IL-3 and stem cell factor. J Immunol 155: 4024-9

32. Kirshenbaum A. (2000) Regulation of mast cell number and function. Hematol Oncol Clin North Am 14: 497-516

33. Matsushima Y, Ishikawa O, Kurosawa M, Miyachi Y.J (2000) Stem cell factor and IL-6 do not promote complete maturation of human cultured mast cells from umbilical cord blood cells: an ultrastructural study. Dermatol Sci 24: 4-13

34. Wright SH, Brown J, Knight PA, Thornton EM, Kilshaw PJ, Miller HR. (2002) Transforming growth factor-beta1 mediates coexpression of the integrin subunit alphaE and the chymase mouse mast cell protease-1 during the early differentiation of bone marrow-derived mucosal mast cell homologues. Clin Exp Allergy 32: 315-24

35. Toru H, Ra C, Nonoyama S, Suzuki K, Yata J, Nakahata T (1996) Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4. Int Immunol 8: 1367-73

36. Williams CM, Galli SJ. (2000) The diverse potential effector and immunoregulatory roles of mast cells in allergic disease. J Allergy Clin Immunol 105: 847-59

37. Hjertson M, Sundstrom C, Nilsson K, Nilsson G. (1999) The potential of human mast cell progenitors to differentiate into mature mast cells remains after


[Seite 40↓]

prolonged culture with flt3 ligand, interleukin-3 or granulocyte-macrophage colony stimulating factor. Br J Haematol 104: 516-22

38. Welker P , Grabbe J, Zuberbier T, Henz BM. (1997) GM-CSF downregulates expression of tryptase, Fc(epsilon)RI(alpha) and histamine in HMC-1 Mast cells. Int Arch Allergy Immunol 113: 284-86

39. Kirshenbaum AS, Worobec AS, Davis TA, Goff JP, Semere T, Metcalfe DD. (1998) Inhibition of human mast cell growth and differentiation by interferon gamma-1b. Exp Hematol 26: 245-51

40. Zhao ZZ, Sugerman PB, Walsh LJ, Savage NW. (2002) Expression of RANTES and CCR1 in oral lichen planus and association with mast cell migration. J Oral Pathol Med 31: 158-62

41. Bochner BS, Schleimer RP (2002) Mast cells, basophils, and eosinophils: distinct but overlapping pathways for recruitment.Immunol Rev 2001 179: 5-15

42. Olsson N, Piek E, ten Dijke P, Nilsson G. (2000) Human mast cell migration in response to members of the transforming growth factor-beta family. J Leukoc Biol 67: 350-6

43. Nilsson G, Mikovits JA, Metcalfe DD, Taub DD (1999) Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB. Blood 93: 2791-7

44. Hartmann K, Henz BM, Kruger-Krasagakes S, Kohl J, Burger R, Guhl S, Haase I, Lippert U, Zuberbier T. (1997) C3a and C5a stimulate chemotaxis of human mast cells. Blood 1997 89: 2863-70

45. Henz BM, Maurer M, Lippert U, Worm M, Babina M (2001) Mast cells as initiators of immunity and host defense. Exp Dermatol 10: 1-10

46. Piliponsky AM, Levi-Schaffer F (2000) Regulation of apoptosis in mast cells. Apoptosis 5: 435-41

47. Gommerman JL, Berger SA. (1998) Protection from apoptosis by steel factor but not interleukin-3 is reversed through blockade of calcium influx. Blood 91: 1891-900

48. Dror Y, Leaker M, Caruana G, Bernstein A, Freedman MH. (2000) Mastocytosis cells bearing a c-kit activating point mutation are characterized by hypersensitivity to stem cell factor and increased apoptosis. Br J Haematol 108: 729-36


[Seite 41↓]

49. Chung KF. Anti-IgE therapy of asthma. (2002) Curr Opin Investig Drugs 3: 1157-60

50. Lippert U, Welker P , Kruger-Krasagakes S, Moller A, Henz BM. (1996) Modulation of in vitro cytokine release from human leukemic mast cells (HMC-1) by glucocorticoids Skin Pharmacol. 9: 93-8

51. Campbell AM, Bousquet J. (1993) Anti-allergic activity of H1 blockers. Int Arch Allergy Immunol 101: 308-10

52. Balzano G, Fuschillo S, Gaudiosi C. (2002) Leukotriene receptor antagonists in the treatment of asthma: an update. Allergy 57 Suppl 72: 16-9

53. Denburg JA (1995) Differentiation of human basophils and mast cells, In: Human basophils and mast cells: Biological aspects (ed. G. Marone). Chem Immunol, p.49, Karger, Basel

54. Huang S, Terstappen LW (1994) Lymphoid and myeloid differentiation of single human CD34+, HLA-DR+, CD38- hematopoietic stem cells. Blood 83: 1515-26

55. Ghannadan M, Baghestanian M, Wimazal F, Eisenmenger M, Latal D, Kargul G, Walchshofer S, Sillaber C, Lechner K, Valent P. (1998) Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies. J Invest Dermatol 111: 689-95

56. Zuberbier T, Welker P , Grabbe J, Henz BM. (2001) Effect of granulocyte macrophage colony-stimulating factor in a patient with benign systemic mastocytosis. Br J Dermatol 145: 661-6

57. Levi-Schaffer F, Austen KF, Gravallese PM, Stevens RL. (1986) Coculture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells Proc Natl Acad Sci U S A 83: 6485-8

58. Welker P , Grabbe J, Hakimi J, Wall AF, Ostmeier H, Czarnetzki BM ( 1992) Fibroblast-derived factors induce different mast cell characteristics in human myeloid cell lines and peripheral monocytes. Int Arch Allergy Appl Immunol 99: 337-339

59. Huang E, Nocka K, Beier DR, Chu TY, Buck J, Lahm HW, Wellner D, Leder P, Besmer P. (1990) The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus Cell 63: 225-33

60. Qiu FH, Ray P, Brown K, Barker PE, Jhanwar S, Ruddle FH, Besmer P (1988) Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase


[Seite 42↓]

family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J 7: 1003-11

61. Bischoff SC, Sellge G. (2002) Mast cell hyperplasia: role of cytokines. Int Arch Allergy Immunol 127: 118-22

62. Tsuji K, Lyman SD, Sudo T, Clark SC, Ogawa M. (1992) Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood 79: 2855-60

63. Lowry PA, Deacon D, Whitefield P, McGrath HE, Quesenberry PJ (1992) Stem cell factor induction of in vitro murine hematopoietic colony formation by "subliminal" cytokine combinations: the role of "anchor factors". Blood 80: 663-9

64. Andrews RG, Bartelmez SH, Knitter GH, Myerson D, Bernstein ID, Appelbaum FR, Zsebo KM. (1992) A c-kit ligand, recombinant human stem cell factor, mediates reversible expansion of multiple CD34+ colony-forming cell types in blood and marrow of baboons. Blood. 80: 920-7

65. Andrews RG, Bensinger WI, Knitter GH, Bartelmez SH, Longin K, Bernstein ID, Appelbaum FR, Zsebo KM. (1992) The ligand for c-kit, stem cell factor, stimulates the circulation of cells that engraft lethally irradiated baboons. Blood 80: 2715-20

66. Moore S, McDiarmid LA, Hughes TP (2000) Stem cell factor and chronic myeloid leukemia CD34+ cells. Leuk Lymphoma 38: 211-20

67. Lapidot T (2001) Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions. Ann N Y Acad Sci 938: 83-95

68. Sundstrom M, Alfredsson J, Olsson N, Nilsson G. (2001) Exp Cell Res Jul 267: 144-51.

69. Galli SJ, Iemura A, Garlick DS, Gamba-Vitalo C, Zsebo KM, Andrews RG. (1993) Reversible expansion of primate mast cell populations in vivo by stem cell factor. J Clin Invest 91: 148-52

70. Oliveira SH, Lukacs NW (2001) Stem cell factor and igE-stimulated murine mast cells produce chemokines (CCL2, CCL17, CCL22) and express chemokine receptors. Inflamm Res 50: 168-74

71. Dastych J, Metcalfe DD (1994) Stem cell factor induces mast cell adhesion to fibronectin. J Immunol 152: 213-9


[Seite 43↓]

72. Karimi K, Redegeld FA, Blom R, Nijkamp FP (2000) Stem cell factor and interleukin-4 increase responsiveness of mast cells to substance P. Exp Hematol 28: 626-34

73. Brazis P, Queralt M, de Mora F, Ferrer LI, Puigdemont A (2000) Stem cell factor enhances IgE-mediated histamine and TNF-alpha release from dispersed canine cutaneous mast cells.Vet Immunol Immunopathol 75: 97-108

74. Schmidt-Choudhury A, Meissner J, Seebeck J, Goetzl EJ, Xia M, Galli SJ, Schmidt WE, Schaub J, Wershil BK (1999) Stem cell factor influences neuro-immune interactions: the response of mast cells to pituitary adenylate cyclase activating polypeptide is altered by stem cell factor. Regul Pept 83: 73-80

75. Wershil BK, Tsai M, Geissler EN, Zsebo KM, Galli SJ (1992) The rat c-kit ligand, stem cell factor, induces c-kit receptor-dependent mouse mast cell activation in vivo. Evidence that signaling through the c-kit receptor can induce expression of cellular function. J Exp Med 175: 245-55

76. Iemura A, Tsai M, Ando A, Wershil BK, Galli SJ (1994) The c-kit ligand, stem cell factor, promotes mast cell survival by suppressing apoptosis. Am J Pathol 144: 321-8

77. Büttner C, Henz BM, Welker P , Sepp NT, Grabbe J (1998) Identification of activating c-kit Mutations in Adult-, but not in childhood-onset indolent mastocytosis: a possible explanation for divergent clinical behavior. J Invest Dermatol 111: 1227-31

78. Hermes B, Feldmann-Böddeker, Welker P , Algermissen B, Steckelings MU, Grabbe J, Henz BM (2000) Alterration sof mast cell proteases and c-kit in human cutaneous scar Tissue. J Invest Dermatol 114: 51-55

79. Furitsu T, Tsujimura T, Tono T, Ikeda H, Kitayama H, Koshimizu U, Sugahara H, Butterfield JH, Ashman LK, Kanayama Y (1993) Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. Clin Invest 92: 1736-44

80. Welker P , Grabbe J, Czarnetzki BM, (1995) Human Keratinocytes release mast cell differention factors other than stem cell factor In Arch Allergy Immunol 107: 139-141


[Seite 44↓]

81. Aloe L, Bracci-Laudiero L, Bonini S, Manni L (1997) The expanding role of nerve growth factor: from neurotrophic activity to immunological diseases. Allergy 52, 883

82. Marshall JS, Waserman S (1995) Mast cells and the nerves - potential interactions in the contex of cronic disease. Clin Exp Allergy 25: 102-110

83. Ulrich A, Gray A, Berman C (1983) Human beta-nerve growth factor gene sequence highly homologous to that of mouse. Nature 303, 821

84. Cartwright M, Mikheev AM, Heinrich G (1994) Expression of neurotrophic genes in human fibroblasts: differential regulation of the brain-derived neurotrophic factor gene. Int J Dev Neurosci 12, 685

85. Patrick CW jr, Kukreti S, McIntire LV (1996) Quantitative effects of peripheral monocytes and nerve growth factor on CNS neural morphometric outgrowth parameters in vitro. Exp Neurol 138, 277

86. Pincelli C, Sevignani C, Manfredini R, Grande A, Fantini F, Bracci-Laudiero L, Aloe L, Ferrari S, Cossarizza A, Giannetti A (1994) Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes. J Invest Dermatol 103, 13

87. Santambrogio L, Benedetti M, Chao M.., Muzaffar R, Kulig K, Gabellini N, Hochwald G. (1993) Nerve growth factor production by lymphocytes. J Immunol 153, 4488

88. Leon A., Buriani A., Dal-Toso R., Fabris M., Romanello S, Aloe L, Levi-Montalcini R (1994) Mast cell synthesize, store and release nerve growth factor. Proc Natl Acad Sci USA 91, 3739

89. Tam SY, Tsai M, Yamaguchi M, Yano K, Butterfield JH, Galli SJ (1997) Expression of functional TrkA receptor tyrosine kinase in the HMC-1 human mast cell line and in human mast cells. Blood 90: 1807-20

90. Nilsson G, Forsberg-Nilsson K, Xiang Z, Hallbook F, Nilsson K, Metcalfe DD (1997) Human mast cells express functional TrkA and are a source of nerve growth factor. Eur J Immunol 27: 2295-301

91. Urashima R, Mihara M (1998) Cutaneous nerves in atopic dermatitis. A histological, immunohistological and electron microscopic study. Virchow Arch 432: 363-70

92. Aloe L, Levi-Montalcini R (1997) Mast cells increase in tissues of neonatal rats injected with the nerve growth factor. Brain Res 133, 358


[Seite 45↓]

93. Kannan Y., Matsuda H., Ushio H., Kawamoto K. & Shimada Y. (1993) Murine granulocyte-macrophage and mast cell colony formation promoted by nerve growth factor. Int Arch Allergy Immunol 101, 362

94. Kawamoto K., Okada T., Kannan Y., Ushio H., Matsumoto M. & Matsuda H. (1995) Nerve growth factor prevents apoptosis of rat peritoneal mast cells through the trk proto-oncogene receptor. Blood 86, 4638

95. Matsuda H., Kannan Y., Ushio H., Kiso Y., Kanemoto T., Susuki H. & Kitamura Y. (1991) Nerve growth factor induces development of connective tissue-type mast cells in vitro from murine bone marrow cells. J Exp Med 174, 7

96. Tal M. and Liberman R. (1997) Local injection of nerve growth factor (NGF) triggers degranulation of mast cells in rat paw. Neurosci Lett 221, 129

97. Blennerhassett MG, Bienenstock J (1998) Sympathetic nerve contact causes maturation of mast cells in vitro. J Neurobiol 35: 173-82

98. Welker P , Peckenschneider N, Serowka F, Henz BM, Fischer A (2002) : neurotrophins as members of the cytokine network in the skin - role in pathogenesis of Atopic Dermatitis Arch Derm Res 294: 65

99. Zuberbier T, Lelke A, Sänger K, Welker P , Guhl S, Henz BM (2001) Comparison of mast cell precursors and cultured mast cells from the cord blood of children with atopic and nonatopic parents. Int Arch Allergy Immunol 124: 304-6

100. Welker P , Grabbe J, Zuberbier T, Henz BM (1997) GM-CSF downregulates expression of tryptase, Fc(RI( and histamine in HMC-1 mast cells. Int Arch Allergy Immunol 113: 284-286

101. Lopez AF, Elliott MJ, Woodcock J, Vadas MA. (1992) GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells. Immunol Today 13: 495-500

102. Okubo T, Yanai N, Watanabe S, Arai K, Obinata M. (2000) Effect of human granulocyte-macrophage colony stimulating factor (hGM-CSF) on lymphoid and myeloid differentiation of sorted hematopoietic stem cells from hGM-CSF receptor gene transgenic mice. J Biochem (Tokyo) 127: 591-6

103. Bressler RB, Thompson HL, Keffer JM, Metcalfe DD (1989) Inhibition of the growth of IL-3-dependent mast cells from murine bone marrow by recombinant granulocyte macrophage-colony-stimulating factor. J Immunol 143: 135-9

104. Du Z, Li Y, Xia H, Irani AM, Schwartz LB. (1997) Recombinant human granulocyte-macrophage colony-stimulating factor (CSF), but not recombinant human granulocyte CSF, down-regulates the recombinant human stem cell factor-


[Seite 46↓]

dependent differentiation of human fetal liver-derived mast cells. J Immunol 1997 159: 838-45

105. Zuberbier T, Welker P , Grabbe J, Henz BM (2001) Effect of granulocyte macrophage colony-stimulating factor in a patient with benign systemic mastocytosis Br J Dermatol 145: 661-6

106. Gabrilove JL, Wong G, Bollenbacher E, White K, Kojima S, Wilson EL. (1993) Basic fibroblast growth factor counteracts the suppressive effect of transforming growth factor-beta 1 on human myeloid progenitor cells. Blood 81: 909-15

107. Li CY, Baek JY. (2002) Mastocytosis and fibrosis: role of cytokines. Int Arch Allergy Immunol 127: 123-6

108. Welker P , Foitzik K, Bulfone-Paus S, Henz BM, Paus R. (1997) Hair cycle-dependent changes in the gene expression and protein content of transforming factor beta 1 and beta3 in murine skin. Arch Dermatol Res 289: 554-7

109. Costa JJ, Demetri GD, Harrist TJ, Dvorak AM, Hayes DF, Merica EA, Menchaca DM, Gringeri AJ, Schwartz LB, Galli SJ (1996) Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo. J Exp Med 183: 2681-6

110. Scott G, Ewing J, Ryan D, Abboud C. Stem cell factor regulates human melanocyte-matrix interactions.Pigment Cell Res 7: 44-51

111. Guo CS, Wehrle-Haller B, Rossi J, Ciment G. (1997) Autocrine regulation of neural crest cell development by steel factor. Dev Biol 184: 61-9

112. Flanagan JG, Chan DC, Leder P (1991) Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell 64: 1025-35

113. Wehrle-Haller B, Weston JA (1995) Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway. Development 121: 731-42

114. Huang S, Luca M, Gutman M, McConkey DJ, Langley KE, Lyman SD, Bar-Eli M. (1996) Enforced c-KIT expression renders highly metastatic human melanoma cells susceptible to stem cell factor-induced apoptosis and inhibits their tumorigenic and metastatic potential. Oncogene 13: 2339-47

115. Schadendorf D, Kohlmus C, Gawlik C, Suter L, Czarnetzki BM (1995) Mast cells in melanocytic tumours Arch Dermatol Res 287: 452-6


[Seite 47↓]

116. Grutzkau A, Kruger-Krasagakes S, Baumeister H, Schwarz C, Kogel H, Welker P , Lippert U, Henz BM, Moller A (1998) Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206. Mol Biol Cell 9: 875-84

117. Nurnberg W, Tobias D, Otto F, Henz BM, Schadendorf D. (1999) Expression of interleukin-8 detected by in situ hybridization correlates with worse prognosis in primary cutaneous melanoma. J Pathol 189: 546-51

118. Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, Fusenig NE (1988) Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 106: 761-7

119. Di Girolamo N, Wakefield D (2000). In vitro and in vivo expression of interstitial collagenase/MMP-1 by human mast cells Dev Immunol 7: 131-42

120. Grabbe J, Kors C, Büttner C, Artuc M, Henz BM, Welker P ( (1998) Regulation of SCF expression in human keratinocytes by retinoid acid and dexamethason Arch Derm Res 290: 66

121. Zhao ZZ, Savage NW, Sugerman PB, Walsh LJ 2002 Mast cell/T cell interactions in oral lichen planus. J Oral Pathol Med 31: 189-95

122. Gibbs BF, Wierecky J, Welker P , Henz BM, Wolff HH, Grabbe J (2001) Human skin mast cells rapidly release preformed and newly generated TNF-alpha and IL-8 following stimulation with anti-IgE and other secretagogues .J Exp Dermatol 2001 10: 312-20

123. Moller A, Lippert U, Lessmann D, Kolde G, Hamann K, Welker P , Schadendorf D, Rosenbach T, Luger T, Czarnetzki BM (1993) Human mast cells produce IL-8. J Immunol 151: 3261-6

124. Inamura N, Mekori YA, Bhattacharyya SP, Bianchine PJ, Metcalfe DD (1998) Induction and enhancement of Fc(epsilon)RI-dependent mast cell degranulation following coculture with activated T cells: dependency on ICAM-1- and leukocyte function-associated antigen (LFA)-1-mediated heterotypic aggregation. J Immunol 160: 4026-33

125. Yoshikawa T, Imada T, Nakakubo H, Nakamura N, Naito K. (2001) Rat mast cell protease-I enhances immunoglobulin E production by mouse B cells stimulated with interleukin-4. Immunology 104: 333-40


[Seite 48↓]

126. Welker P , Grabbe J, Zuberbier T, Henz BM. (1999) IgE downmodulates stem cell factor-driven mast cell development from cultured peripheral blood mononuclear cells. Int Arch Allergy Immunol 118: 292-4

127. Asai K, Kitaura J, Kawakami Y, Yamagata N, Tsai M, Carbone DP, Liu FT, Galli SJ, Kawakami T. (2001) Regulation of mast cell survival by IgE. Immunity 14: 791-800

128. Rossmann ED, Lewin N, Jeddi-Tehrani M, Osterborg A, Mellstedt H (2002) Intracellular T cell cytokines in patients with B cell chronic lymphocytic leukaemia (B-CLL). Eur J Haematol 68: 299-306

129. Tachimoto H, Ebisawa M, Hasegawa T, Kashiwabara T, Ra C, Bochner BS, Miura K, Saito H (2000). Reciprocal regulation of cultured human mast cell cytokine production by IL-4 and IFN-gamma. J Allergy Clin Immunol 106: 141-9

130. Yoshizawa Y, Nomaguchi H, Izaki S, Kitamura K. (2002) Serum cytokine levels in atopic dermatitis. Clin Exp Dermatol 27: 225-9

131. Bohm I, Bauer R. Th1 cells, Th2 cells and atopic dermatitis Hautarzt 1997 48: 223-7

132. Moller A, Lippert U, Lessmann D, Kolde G, Hamann K, Welker P , Schadendorf D, Rosenbach T, Luger T, Czarnetzki BM (1993) Human mast cells produce IL-8. J Immunol 151: 3261-6

133. Baram D, Vaday GG, Salamon P, Drucker I, Hershkoviz R, Mekori YA (2002) Human mast cells release metalloproteinase-9 on contact with activated T cells: juxtacrine regulation by TNF-alpha. J Immunol 167: 4008-16

134. Toth-Jakatics R, Jimi S, Takebayashi S, Kawamoto N. (2000) Cutaneous malignant melanoma: correlation between neovascularization and peritumor accumulation of mast cells overexpressing vascular endothelial growth Hum Pathol 31: 955-60

135. Erkilic S, Erbagci Z. (2001) The significance of mast cells associated with basal cell carcinoma. J Dermatol 28: 312-5

136. Calamandrei G, Alleva E (1995) Neuronal growth factors, neurothrophins and memory deficience. Behav Brain Res 66: 129-32

137. Purcell WM, Westgate C, Atterwill CK (1996) Rat brain mast cells. An in vitro paradigm for assessing the toxic effects of therapeutics. Neurotoxicology 17: 845-50


[Seite 49↓]

138. Horigome K, Pryor JC, Bullock ED, Johnson EM JR (1993) Mediator release from mast cells by nerve growth factor. Neurothrophin specificity and receptor mediation. J Biol Chem 268: 14881-7

139. Lai KO, Fu WY, Ip FC Ip NY (1998) coning and expression of a novel neurothrophin, NT-7, from carp. Mol Cell Neurosci 11: 64-76

140. Marshall JS, Gauldie L, Nielsen L, Bienenstock J (1993) Leukemia inhibitory factor production by rat mast cells. Eur J Immunol 23: 2116-20

141. Klein R., Jing S., Venkata N., O'Rouke E. & Barbacid M. (1991) The trk proto-oncogen encodes a receptor for nerve growth factor. Cell 65, 189

142. Leung DY (1999) : Pathogenesis of atopic dermatitis. J Allergy Clin Immunol 104 (Suppl), S99-108

143. Scholzen T, Armstrong CA, Bunnett NW, Luger TA, Olerud JE, Ansel JC (1998) Neuropeptides in the skin: interactions between neuroendocrine and the skin immun systems. Exp Dermatol 7: 81-96

144. Luger TA (2002) Neuromediators-a crucial component of the skin immune system. J Dermatol Sci 30: 87-93

145. Marshall JS, Waserman S (1995) Mast cells and the nerves - potential interactions in the contex of cronic disease. Clin Exp Allergy 25: 102-110

146. Osterle LS, Cowen T, Rustin MN (1995) Neuropeptides in the skin of patients with atopic dermatitis. Clin Exp Dermatol 20: 482-7

147. Skaper SD, Facci L, Romanello S, Leon A (1996) Mast cell activation causes delayed neurodegeneration in mixed hippocampal cultures via the nitric oxide pathway. J Neurochem 66: 1157-66

148. Janiszewski J, Bienenstock J, Blennerhassett MG (1990) Activation of rat peritoneal mast cells in coculture with sympathetic neurons alters neuronal physiology Brain Behav Immun. 4: 139-50

149. Naukkarinen A, Harvima IT, Aalto ML, Horsmanheimo M (1994) Mast cell tryptase and chymase are potential regulators of neurogenic inflammation in psoriatic skin. Int J Dermatol 33: 361-6

150. Blennerhassett MG, Bienenstock J (1998) Sympathetic nerve contact causes maturation of mast cells in vitro. J Neurobiol 35: 173-82

151. Getchell ML, Kulkarni-Narly A, Takami S, Albers KM, Getchell TV (1995) Age-dependent phenotypic switching of mast cells in NGF transgenic mice. NeuroReport 6: 1261-6


[Seite 50↓]

152. Bullock ED, Johnson EMJr (1996) Nerve growth factor induces the expression of certain cytokine genes and bcl-2 in mast cells: Potential role in survival promotion. J Biol Chem 271, 27500

153. Bruni A., Bignon E., Boarato E, Leon A, Toffano G. (1982) Interaction between nerve growth factor and lysophosphatidylserine on rat peritoneal mast cells. FEBS Lett 138, 190

154. Renauld JC (2001) New insights into the role of cytokines in asthma. J Clin Pathol 54: 577-89.

155. Yu LC, Perdue MH (2001) Role of mast cells in intestinal mucosal function: studies in models of hypersensitivity and stress. Immunol Rev 179: 61-73

156. Prue H Hart (2001) Regulation of the inflammatory response in asthma by mast cell products . Immunology and Cell Biology 79: 149 -155

157. Grabbe J, Welker P , Humke S, Grewe M, Schopf E, Henz BM, Krutmann J (1996) High-dose ultraviolet A1 (UVA1) , but not UVA/UVB therapy, decreases IgE-binding cells in lesional skin of patients with atopic eczema Invest Dermatol 107: 419-22

158. Clydesdale GJ, Dandie GW, Muller HK. (2001) Ultraviolet light induced injury: immunological and inflammatory effects Immunol Cell Biol 79: 547-68

159. Cox JS (1971) Disodium cromoglycate. Mode of action and its possible relevance to the clinical use of the drug. Br J Dis Chest 65: 189-204

160. Reinsprecht M, Pecht I, Schindler H, Romanin C. (1992) Potent block of Cl- channels by antiallergic drugs Biochem Biophys Res Commun 88: 957-63

161. Alton EW, Norris AA. (1996) Chloride transport and the actions of nedocromil sodium and cromolyn sodium in asthma J Allergy Clin Immunol 98(5 Pt 2) :S102-5; discussion S105-6

162. Borish L, Williams J, Johnson S, Mascali JJ, Miller R, Rosenwasser LJ (1992) Anti-inflammatory effects of nedocromil sodium: inhibition of alveolar macrophage function Clin Exp Allergy 22: 984-90

163. Farrar JR, Rainey DK, Norris AA. (1995) Pharmacologic modulation of Th1 and Th2 cell subsets by nedocromil sodium. Int Arch Allergy Immunol 107 (1-3) 414-5 :

164. Welker P , Lippert U, Nurnberg W, Kruger-Krasagakes S, Moller A, Czarnetzki BM. (1996) Glucocorticoid-induced modulation of cytokine secretion from normal and leukemic human myelomonocytic cells. Int Arch Allergy Immunol 109: 110-5


[Seite 51↓]

165. Lippert U, Welker P , Kruger-Krasagakes S, Moller A, Henz BM. (1996) Modulation of in vitro cytokine release from human leukemic mast cells (HMC-1) by glucocorticoids. Skin Pharmacol 9: 93-8

166. Kassel O, Sancono A, Kratzschmar J, Kreft B, Stassen M, Cato AC (2001) Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO J 20: 7108-16

167. Da Silva CA, Kassel O, Mathieu E, Massard G, Gasser B, Frossard N (2002) Inhibition by glucocorticoids of the interleukin-1beta-enhanced expression of the mast cell growth factor SCF. Br J Pharmacol 135: 1634-40

168. Reitamo S, Remitz A, Kyllonen H, Saarikko J, Granlund H (2002) Topical noncorticosteroid immunomodulation in the treatment of atopic dermatitis. Am J Clin Dermatol 3: 381-8

169. Zuberbier T, Chong SU, Grunow K, Guhl S, Welker P , Grassberger M, Henz BM (2001) The ascomycin macrolactam pimecrolimus (Elidel, SDZ ASM 981) is a potent inhibitor of mediator release from human dermal mast cells and peripheral blood basophils. J Allergy Clin Immunol 108: 275-80

170. Cheer SM, Plosker GL (2001) Tacrolimus ointment. A review of its therapeutic potential as a topical therapy in atopic dermatitis. Am J Clin Dermatol 2: 389-406

171. Baroody FM, Naclerio RM (2000) Antiallergic effects of H1-receptor antagonists. Allergy 55 Suppl 64: 17-27

172. Lippert U, Moller A, Welker P , Artuc M, Henz BM (2000) Inhibition of cytokine secretion from human leukemic mast cells and basophils by H1- and H2-receptor antagonists. Exp Dermatol; 9: 118-24

173. Chari S, Clark-Loeser L, Shupack J, Washenik K (2002) A role for leukotriene antagonists in atopic dermatitis? Am J Clin Dermatol 2: 1-6

174. Rice KD, Tanaka RD, Katz BA, Numerof RP, Moore WR (1998) Inhibitors of tryptase for the treatment of mast cell-mediated diseases. Curr Pharm Des 4: 381-96

175. Luger TA (1995) Cytokine treatment of mast-cell-mediated skin diseases. Exp Dermatol 4: 277-80

176. Kahari VM, Saarialho-Kere U. (1997) Matrix metalloproteinases in skin. Exp Dermatol 6: 199-213


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