2008-12-22Zeitschriftenartikel
Thrombin induces broad spectrum proteolysis in human serum samples
O'Mullan, Patrick; Craft, David; Yi, Jizu; Gelfand, Craig A.
Background: During clotting, α thrombin cleaves fibrinogen releasing fibrinopeptide A (FPA). FPA is easily identified in serum using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry ...