Browsing by Author "Semyachkina-Glushkovskaya, Oxana"

Now showing items 1-7 of 7

2021-11-02Zeitschriftenartikel

A Novel Method to Stimulate Lymphatic Clearance of Beta-Amyloid from Mouse Brain Using Noninvasive Music-Induced Opening of the Blood–Brain Barrier with EEG Markers

Semyachkina-Glushkovskaya, Oxana; Khorovodov, Alexander; Fedosov, Ivan; Pavlov, Alexey; Shirokov, Alexander; Sharif, Ali Esmat; Dubrovsky, Alexander; Blokhina, Inna; Terskov, Andrey; Navolokin, Nikita; Evsukova, Arina; Karandin, Georgy; Elovenko, Dariya; Tzoy, Maria; Ageev, Vasily; Agranovich, Ilana; Telnova, Valeriya; Tsven, Anna; Saranceva, Elena; Iskra, Tatyana; Kurths, Jürgen

The lymphatic system of the brain meninges and head plays a crucial role in the clearance of amyloid-β protein (Aβ), a peptide thought to be pathogenic in Alzheimer’s disease (AD), from the brain. The development of methods ...
2018-11-30Zeitschriftenartikel

Blood−Brain Barrier, Lymphatic Clearance, and Recovery: Ariadne’s Thread in Labyrinths of Hypotheses

Semyachkina-Glushkovskaya, Oxana; Postnov, Dmitry; Kurths, Jürgen

The peripheral lymphatic system plays a crucial role in the recovery mechanisms after many pathological changes, such as infection, trauma, vascular, or metabolic diseases. The lymphatic clearance of different tissues from ...
2021-06-28Zeitschriftenartikel

Brain Mechanisms of COVID-19-Sleep Disorders

Semyachkina-Glushkovskaya, Oxana; Mamedova, Aysel; Vinnik, Valeria; Klimova, Maria; Saranceva, Elena; Ageev, Vasily; Yu, Tingting; Zhu, Dan; Penzel, Thomas; Kurths, Jürgen

2020 and 2021 have been unprecedented years due to the rapid spread of the modified severe acute respiratory syndrome coronavirus around the world. The coronavirus disease 2019 (COVID-19) causes atypical infiltrated pneumonia ...
2021-11-24Zeitschriftenartikel

Night Photostimulation of Clearance of Beta-Amyloid from Mouse Brain: New Strategies in Preventing Alzheimer’s Disease

Semyachkina-Glushkovskaya, Oxana; Penzel, Thomas; Blokhina, Inna; Khorovodov, Alexander; Fedosov, Ivan; Yu, Tingting; Karandin, Georgy; Evsukova, Arina; Elovenko, Dariya; Adushkina, Viktoria; Shirokov, Alexander; Dubrovskii, Alexander; Terskov, Andrey; Navolokin, Nikita; Tzoy, Maria; Ageev, Vasily; Agranovich, Ilana; Telnova, Valeriya; Tsven, Anna; Kurths, Jürgen

The deposition of amyloid-β (Aβ) in the brain is a risk factor for Alzheimer’s disease (AD). Therefore, new strategies for the stimulation of Aβ clearance from the brain can be useful in preventing AD. Transcranial ...
2019-12-19Zeitschriftenartikel

Photodynamic Opening of the Blood−Brain Barrier Using Different Photosensitizers in Mice

Semyachkina-Glushkovskaya, Oxana; Borisova, Ekaterina; Mantareva, Vanya; Angelov, Ivan; Eneva, Ivelina; Terskov, Andrey; Mamedova, Aysel; Shirokov, Alexander; Khorovodov, Alexander; Klimova, Maria; Agranovich, Ilana; Blokhina, Inna; Lezhnev, Nikita; Kurths, Jurgen

In a series of previous studies, we demonstrated that the photodynamic therapy (PDT), as a widely used tool for treatment of glioblastoma multiforme (GBM), also site-specifically opens the blood–brain barrier (BBB) in ...
2020-06-26Zeitschriftenartikel

Photostimulation of Extravasation of Beta-Amyloid through the Model of Blood-Brain Barrier

Zinchenko, Ekaterina; Klimova, Maria; Mamedova, Aysel; Agranovich, Ilana; Blokhina, Inna; Antonova, Tatiana; Terskov, Andrey; Shirokov, Alexander; Navolokin, Nikita; Morgun, Andrey; Osipova, Elena; Boytsova, Elizaveta; Yu, Tingting; Zhu, Dan; Kurths, Jürgen; Semyachkina-Glushkovskaya, Oxana

Alzheimer’s disease (AD) is an incurable pathology associated with progressive decline in memory and cognition. Phototherapy might be a new promising and alternative strategy for the effective treatment of AD, and has been ...
2020-08-31Zeitschriftenartikel

Sleep as a Novel Biomarker and a Promising Therapeutic Target for Cerebral Small Vessel Disease: A Review Focusing on Alzheimer’s Disease and the Blood-Brain Barrier

Semyachkina-Glushkovskaya, Oxana; Postnov, Dmitry; Penzel, Thomas; Kurths, Jürgen

Cerebral small vessel disease (CSVD) is a leading cause of cognitive decline in elderly people and development of Alzheimer’s disease (AD). Blood–brain barrier (BBB) leakage is a key pathophysiological mechanism of amyloidal ...