2022-05-05Zeitschriftenartikel
Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells
Burt, Philipp; Cornelis, Rebecca; Geißler, Gustav; Hahne, Stefanie; Radbruch, Andreas; Chang, Hyun-Dong; Thurley, Kevin
Memory plasma cells constitutively produce copious amounts of antibodies, imposing a critical risk factor for autoimmune disease. We previously found that plasma cell survival requires secreted factors such as APRIL and ...