Browsing by Author "Delpero, Manuel"

Now showing items 1-4 of 4

2021-12-15Zeitschriftenartikel

A deletion containing a CTCF-element in intron 8 of the Bbs7 gene is partially responsible for juvenile obesity in the Berlin Fat Mouse

Krause, Florian; Mohebian, Kourosh; Delpero, Manuel; Hesse, Deike; Kühn, Ralf; Arends, Danny; Brockmann, Gudrun A

The Berlin Fat Mouse Inbred (BFMI) line is a model for juvenile obesity. Previous studies on crosses between BFMI and C57Bl/6N (B6N) have identified a recessive defect causing juvenile obesity on chromosome 3 (jObes1). ...
2021-10-23Zeitschriftenartikel

Identification of four novel QTL linked to the metabolic syndrome in the Berlin Fat Mouse

Delpero, Manuel; Arends, Danny; Sprechert, Maximilian; Krause, Florian; Kluth, Oliver; Schürmann, Annette; Brockmann, Gudrun A; Hesse, Deike

Background The Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and the metabolic syndrome. This study aimed to identify genetic variants associated with impaired glucose metabolism using the obese ...
2023-04-13Kumulative Dissertation

Identification of new candidate genes associated with metabolic traits applying a multiomics approach in the obese mouse model BFMI861

Delpero, Manuel

Hintergrund: Die Berlin Fat Mouse Inzuchtlinie (BFMI) ist ein Modell für Adipositas und das metabolische Syndrom. Diese Studie zielte darauf ab, genetische Varianten zu identifizieren, die mit dem gestörten Glukosestoffwechsel ...
2022-06-21Zeitschriftenartikel

QTL-mapping in the obese Berlin Fat Mouse identifies additional candidate genes for obesity and fatty liver disease

Delpero, Manuel; Arends, Danny; Freiberg, Aimée; Brockmann, Gudrun A; Hesse, Deike

The Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and the metabolic syndrome. This study aimed to identify genetic variants associated with liver weight, liver triglycerides, and body weight using the obese ...