Browsing by Author "Pietsch, Kerstin"

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2012-02-01Dissertation

Defining Quercetin-, Caffeic acid- and Rosmarinic acid- mediated life extension in C. elegans

bioassays and expression analyses

Pietsch, Kerstin

Die mittlere Lebenserwartung des Menschen ist über die letzten 200 Jahre kontinuierlich gestiegen. Da Langlebigkeit ohne Gesundheit wenig Wert besitzt, ist es ein zentrales Anliegen, das Auftreten altersbedingter Krankheiten ...
2012-04-05Zeitschriftenartikel

Meta-Analysis of Global Transcriptomics Suggests that Conserved Genetic Pathways are Responsible for Quercetin and Tannic Acid Mediated Longevity in C. elegans

Pietsch, Kerstin; Saul, Nadine; Swain, Suresh C.; Menzel, Ralph; Steinberg, Christian E.W.; Stürzenbaum, Stephen R.

Recent research has highlighted that the polyphenols Quercetin and Tannic acid are capable of extending the lifespan of Caenorhabditis elegans. To gain a deep understanding of the underlying molecular genetics, we analyzed ...
2012-04-12Zeitschriftenartikel

The Nematode Caenorhabditis elegans, Stress and Aging: Identifying the Complex Interplay of Genetic Pathways Following the Treatment with Humic Substances

Menzel, Ralph; Menzel, Stefanie; Swain, Suresh C.; Pietsch, Kerstin; Tiedt, Sophie; Witczak, Jördis; Stürzenbaum, Stephen R.; Steinberg, Christian E.W.

Low concentrations of the dissolved leonardite humic acid HuminFeed® (HF) prolonged the lifespan and enhanced the thermal stress resistance of the model organism Caenorhabditis elegans. However, growth was impaired and ...