Browsing by Author "Reimann, Carolin"

Now showing items 1-5 of 5

2021-09-27Zeitschriftenartikel

Assessment of Albumin ECM Accumulation and Inflammation as Novel In Vivo Diagnostic Targets for Multi-Target MR Imaging

Möckel, Jana; Brangsch, Julia; Reimann, Carolin; Kaufmann, Jan O.; Sack, Ingolf; Mangarova, Dilyana; Avan, Kader; Taupitz, Matthias; Adams, Lisa C.; Keller, Sarah; Ludwig, Antje; Hamm, Bernd; Botnar, Rene; Makowski, Marcus R.

Atherosclerosis is a progressive inflammatory vascular disease characterized by endothelial dysfunction and plaque burden. Extracellular matrix (ECM)-associated plasma proteins play an important role in disease development. ...
2020-11-27Zeitschriftenartikel

Assessment of the hepatic tumor extracellular matrix using elastin-specific molecular magnetic resonance imaging in an experimental rabbit cancer model

Keller, Sarah; Borde, Tabea; Brangsch, Julia; Reimann, Carolin; Avan, Kader; Schulze, Daniel; Buchholz, Rebecca; Kaufmann, Jan Ole; Karst, Uwe; Schellenberger, Eyk; Hamm, Bernd; Makowski, Marcus R.

To investigate the imaging performance of an elastin-specific molecular magnetic resonance imaging (MRI) probe with respect to the extracellular matrix (ECM) in an experimental hepatic cancer model. Twelve rabbits with ...
2022-06-13Zeitschriftenartikel

Iron Oxide Nanoparticles for Visualization of Prostate Cancer in MRI

Avan, Kader; Kaufmann, Jan O.; Mangarova, Dilyana; Moeckel, Jana; Brangsch, Julia; Adams, Lisa C.; Zhao, Jing; Reimann, Carolin; Saatz, Jessica; Traub, Heike; Buchholz, Rebecca; Karst, Uwe; Hamm, Bernd; Makowski, Marcus R.

Prostate cancer (PCa) is one of the most common cancers in men. For detection and diagnosis of PCa, non-invasive methods, including magnetic resonance imaging (MRI), can reduce the risk potential of surgical intervention. ...
2020-09-16Zeitschriftenartikel

Simultaneous molecular MRI of extracellular matrix collagen and inflammatory activity to predict abdominal aortic aneurysm rupture

Adams, Lisa C.; Brangsch, Julia; Reimann, Carolin; Kaufmann, Jan O.; Buchholz, Rebecca; Karst, Uwe; Botnar, Rene; Hamm, Bernd; Makowski, Marcus R.

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease with an up to 80% mortality in case of rupture. Current biomarkers fail to account for size-independent risk of rupture. By combining the information ...
2021-11-22Zeitschriftenartikel

Visualization and Quantification of the Extracellular Matrix in Prostate Cancer Using an Elastin Specific Molecular Probe

Avan, Kader; Brangsch, Julia; Reimann, Carolin; Kaufmann, Jan O.; Mangarova, Dilyana; Moeckel, Jana; Adams, Lisa C.; Zhao, Jing; Saatz, Jessica; Traub, Heike; Buchholz, Rebecca; Karst, Uwe; Hamm, Bernd; Makowski, Marcus R.

Human prostate cancer (PCa) is a type of malignancy and one of the most frequently diagnosed cancers in men. Elastin is an important component of the extracellular matrix and is involved in the structure and organization ...