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Browsing by Author "Loibl, Natalia"

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    • 2020-05-26Zeitschriftenartikel
      Monitoring Dicer‐Mediated miRNA‐21 Maturation and Ago2 Loading by a Dual‐Colour FIT PNA Probe Set 
      Loibl, Natalia; Arenz, Christoph; Seitz, Oliver
      The inhibition of micro RNA (miRNA) maturation by Dicer and loading matured miRNAs into the RNA‐induced silencing complex (RISC) is envisioned as a modality for treatment of cancer. Existing methods for evaluating maturation ...
    • 2022-05-10Dissertation
      Monitoring of Micro RNA Maturation and Its Inhibition in Living Cells 
      Loibl, Natalia
      Im ersten Teil der Arbeit wurde die Verwendung von Präkursor microRNA-21(pre-miR21)-spezifischen Peptidnukleinsäure(PNA)-Sonden zur Inhibierung der Dicer-vermittelnden miRNA-Reifung untersucht. Im Gegensatz zur Arbeitshypothese ...
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