Browsing by Author "Siegert, Markus"

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2020-09-09Zeitschriftenartikel

Adduct of the blistering warfare agent sesquimustard with human serum albumin and its mass spectrometric identification for biomedical verification of exposure

Blum, Marc-Michael; Richter, Annika; Siegert, Markus; Thiermann, Horst; John, Harald

Apart from the well-known sulfur mustard (SM), additional sulfur-containing blistering chemical warfare agents exist. Sesquimustard (Q) is one of them and five times more blistering than SM. It is a common impurity in ...
2021-07-02Zeitschriftenartikel

Alkylated albumin-derived dipeptide C(-HETE)P derivatized by propionic anhydride as a biomarker for the verification of poisoning with sulfur mustard

Richter, Annika; Siegert, Markus; Thiermann, Horst; John, Harald

Sulfur mustard (SM) is a banned chemical warfare agent recently used in the Syrian Arab Republic conflict causing erythema and blisters characterized by complicated and delayed wound healing. For medical and legal reasons, ...
2023-07-27Dissertation

Mass spectrometric detection and characterization of covalent reaction products between the chemical warfare agent sulfur mustard and human serum albumin and small molecules

Siegert, Markus

Schwefellost (SM) ist ein verbotener chemischer Kampfstoff. Nach Aufnahme über die Haut führt SM zu einer Reihe von Symptomen. Auf der molekularen Ebene beruht die Toxizität von SM auf der Reaktion mit DNA und Proteinen. ...