2009-04-14Zeitschriftenartikel
Intrathecal synthesis of tumor markers is a highly sensitive test in the diagnosis of leptomeningeal metastasis from solid cancers
Corsini, Elena; Bernardi, Gaetano; Gaviani, Paola; Silvani, Antonio; Grazia, Ugo de; Ciusani, Emilio; Croci, Danilo; Salmaggi, Andrea
Background: Identification of neoplastic cells in cerebrospinal fluid (CSF) by cytological analysis is the key diagnostic feature of leptomeningeal metastasis (LM). Because of the lack of sensitivity of this test, considerable ...