Browsing by Author "Ren, Bingjian"

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2019-11-08Dissertation

Physiological importance of phospholipid biogenesis in Toxoplasma gondii

Ren, Bingjian

Toxoplasma gondii ist ein obligater intrazellulärer Parasit, der bei Menschen und Nutztieren Toxoplasmose verursacht. Die Phospholipid-Biosynthese ist entscheidend für das erfolgreiche intrazelluläre Überleben und die ...
2017-07-06Zeitschriftenartikel

Taming Parasites by Tailoring Them

Ren, Bingjian; Gupta, Nishith

The next-generation gene editing based on CRISPR (clustered regularly interspaced short palindromic repeats) has been successfully implemented in a wide range of organisms including some protozoan parasites. However, ...
2021-01-06Zeitschriftenartikel

Toxoplasma and Eimeria co-opt the host cFos expression for intracellular development in mammalian cells

Ren, Bingjian; Schmid, Manuela; Scheiner, Mattea; Mollenkopf, Hans-Joachim; Lucius, Richard; Heitlinger, Emanuel; Gupta, Nishith

Successful asexual reproduction of intracellular pathogens depends on their potential to exploit host resources and subvert antimicrobial defense. In this work, we deployed two prevalent apicomplexan parasites of mammalian ...