Browsing by Author "Penzel, Thomas"

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2021-06-28Zeitschriftenartikel

Brain Mechanisms of COVID-19-Sleep Disorders

Semyachkina-Glushkovskaya, Oxana; Mamedova, Aysel; Vinnik, Valeria; Klimova, Maria; Saranceva, Elena; Ageev, Vasily; Yu, Tingting; Zhu, Dan; Penzel, Thomas; Kurths, Jürgen

2020 and 2021 have been unprecedented years due to the rapid spread of the modified severe acute respiratory syndrome coronavirus around the world. The coronavirus disease 2019 (COVID-19) causes atypical infiltrated pneumonia ...
2023-02-06Zeitschriftenartikel

Brain Waste Removal System and Sleep: Photobiomodulation as an Innovative Strategy for Night Therapy of Brain Diseases

Semyachkina-Glushkovskaya, Oxana; Fedosov, Ivan; Penzel, Thomas; Li, Dongyu; Yu, Tingting; Telnova, Valeria; Kaybeleva, Elmira; Saranceva, Elena; Terskov, Andrey; Khorovodov, Alexander; Blokhina, Inna; Kurths, Jürgen; Zhu, Dan

Emerging evidence suggests that an important function of the sleeping brain is the removal of wastes and toxins from the central nervous system (CNS) due to the activation of the brain waste removal system (BWRS). The ...
2016-10-25Zeitschriftenartikel

Modulations of Heart Rate, ECG, and Cardio-Respiratory Coupling Observed in Polysomnography

Penzel, Thomas; Kantelhardt, Jan; Bartsch, Ronny; Riedl, Maik; Kraemer, Jan; Wessel, Niels; Garcia, Carmen; Glos, Martin; Fietze, Ingo; Schöbel, Christoph

The cardiac component of cardio-respiratory polysomnography is covered by ECG and heart rate recordings. However, their evaluation is often underrepresented in summarizing reports. As complements to EEG, EOG, and EMG, these ...
2021-11-24Zeitschriftenartikel

Night Photostimulation of Clearance of Beta-Amyloid from Mouse Brain: New Strategies in Preventing Alzheimer’s Disease

Semyachkina-Glushkovskaya, Oxana; Penzel, Thomas; Blokhina, Inna; Khorovodov, Alexander; Fedosov, Ivan; Yu, Tingting; Karandin, Georgy; Evsukova, Arina; Elovenko, Dariya; Adushkina, Viktoria; Shirokov, Alexander; Dubrovskii, Alexander; Terskov, Andrey; Navolokin, Nikita; Tzoy, Maria;

The deposition of amyloid-β (Aβ) in the brain is a risk factor for Alzheimer’s disease (AD). Therefore, new strategies for the stimulation of Aβ clearance from the brain can be useful in preventing AD. Transcranial ...
2023-06-30Zeitschriftenartikel

Phototherapy of Alzheimer’s Disease: Photostimulation of Brain Lymphatics during Sleep: A Systematic Review

Semyachkina-Glushkovskaya, Oxana; Penzel, Thomas; Poluektov, Mikhail; Fedosov, Ivan; Tzoy, Maria; Terskov, Andrey; Blokhina, Inna; Sidorov, Victor; Kurths, Jürgen

The global number of people with Alzheimer’s disease (AD) doubles every 5 years. It has been established that unless an effective treatment for AD is found, the incidence of AD will triple by 2060. However, pharmacological ...
2020-08-31Zeitschriftenartikel

Sleep as a Novel Biomarker and a Promising Therapeutic Target for Cerebral Small Vessel Disease: A Review Focusing on Alzheimer’s Disease and the Blood-Brain Barrier

Semyachkina-Glushkovskaya, Oxana; Postnov, Dmitry; Penzel, Thomas; Kurths, Jürgen

Cerebral small vessel disease (CSVD) is a leading cause of cognitive decline in elderly people and development of Alzheimer’s disease (AD). Blood–brain barrier (BBB) leakage is a key pathophysiological mechanism of amyloidal ...
2021-07-22Zeitschriftenartikel

The Different Facets of Heart Rate Variability in Obstructive Sleep Apnea

Qin, Hua; Steenbergen, Nicolas; Glos, Martin; Wessel, Niels; Kraemer, Jan F.; Vaquerizo-Villar, Fernando; Penzel, Thomas

Obstructive sleep apnea (OSA), a heterogeneous and multifactorial sleep related breathing disorder with high prevalence, is a recognized risk factor for cardiovascular morbidity and mortality. Autonomic dysfunction leads ...
2021-08-31Zeitschriftenartikel

The Effect of Night Duty of Pharmacists on Sleepiness and Concentration at Daytime

Biechele, Claus Werner; Glos, Martin; Fietze, Ingo; Kurths, Jürgen; Penzel, Thomas

Background: The changing responsibilities of pharmacists contribute to a lack of qualified pharmacists to fill vacant positions, particularly in rural areas. Consequently, pharmacy managers cover various duties, including ...