Browsing by Author "Schleimer, Jan Hendrik"

Now showing items 1-4 of 4

2022-04-01Zeitschriftenartikel

A dynamic clamp protocol to artificially modify cell capacitance

Pfeiffer, Paul; Barreda Tomás, Federico José; Wu, Jiameng; Schleimer, Jan Hendrik; Vida, Imre; Schreiber, Susanne

Dynamics of excitable cells and networks depend on the membrane time constant, set by membrane resistance and capacitance. Whereas pharmacological and genetic manipulations of ionic conductances of excitable membranes are ...
2020-02-07Zeitschriftenartikel

Clusters of cooperative ion channels enable a membrane-potential-based mechanism for short-term memory

Pfeiffer, Paul; Egorov, Alexei; Lorenz, Franziska; Schleimer, Jan Hendrik; Draguhn, Andreas; Schreiber, Susanne

Across biological systems, cooperativity between proteins enables fast actions, supra-linear responses, and long-lasting molecular switches. In the nervous system, however, the function of cooperative interactions between ...
2020-08-04Zeitschriftenartikel

Modifications of sodium channel voltage dependence induce arrhythmia-favouring dynamics of cardiac action potentials

Rose, Pia; Schleimer, Jan Hendrik; Schreiber, Susanne

Heart arrhythmia is a pathological condition where the sequence of electrical impulses in the heart deviates from the normal rhythm. It is often associated with specific channelopathies in cardiac tissue, yet how precisely ...
2013-07-26Dissertation

Spike statistics and coding properties of phase models

Schleimer, Jan Hendrik

Ziel dieser Arbeit ist es eine Beziehung zwischen den biophysikalischen Eigenschaften der Nervenmembran, und den ausgeführten Berechnungen und Filtereigenschaften eines tonisch feuernden Neurons, unter Einbeziehen ...