Browsing by Author "Martitz, Janine"

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2017-07-11Dissertation

Factors impacting the hepatic selenoprotein expression in matters of critical illness

Martitz, Janine

Selenoproteine spielen eine wichtige Rolle in der antioxidativen Abwehr und bei Immunreaktionen. Der Selen(Se)metabolismus wird von Hepatozyten gesteuert, die das Se-Transportprotein Selenoprotein P (SEPP) synthetisieren ...
2014-03-26Zeitschriftenartikel

Hypoxia reduces and redirects selenoprotein biosynthesis

Becker, Niels-Peter; Martitz, Janine; Renko, Kostja; Stoedter, Mette; Hybsier, Sandra; Cramer, Thorsten; Schomburg, Lutz

Selenium deficiency constitutes a risk factor for the incidence and negative course of severe diseases including sepsis, stroke, autoimmune diseases or cancer. In this study, hypoxia is identified as a powerful stimulus ...