Inverse relationship between serum high density lipoprotein and negative syndrome in antipsychotic-naive schizophrenia
dc.contributor.author | Venkatasubramanian, Ganesan | |
dc.contributor.author | Arasappa, Rashmi | |
dc.contributor.author | Rao, Naren P. | |
dc.contributor.author | Behere, Rishikesh V. | |
dc.contributor.author | Kalmady, Sunil | |
dc.contributor.author | Gangadhar, Bangalore N. | |
dc.date.accessioned | 2017-06-17T08:16:06Z | |
dc.date.available | 2017-06-17T08:16:06Z | |
dc.date.created | 2010-07-01 | |
dc.date.issued | 2009-09-16 | |
dc.identifier.issn | 1437-4331 | |
dc.identifier.uri | http://edoc.hu-berlin.de/18452/12179 | |
dc.description.abstract | Background: Recent literature suggests a role for apolipoprotein L (apoL) aberrations in the pathogenesis of schizophrenia. ApoL is almost exclusively associated with apolipoprotein A-I in high-density lipoproteins (HDLs). The objective of this study was to examine the correlation between symptom scores and serum HDL in antipsychotic-naive schizophrenia patients. Methods: In this cross-sectional study, 60 antipsychotic-naive schizophrenia patients were systematically examined for their symptom scores, with good inter-rater reliability. Concurrently, an overnight fasting serum lipid profile from these patients was assessed. Results: Serum HDL had a significant inverse correlation with a total negative syndrome score (ρ=−0.43; p=0.001). Conclusions: The study observation supports the potential role for HDL abnormalities in the genesis of negative symptoms in schizophrenia. Clin Chem Lab Med 2010;48:95–8. | eng |
dc.language.iso | und | |
dc.publisher | Kooperation de Gruyter | |
dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | |
dc.title | Inverse relationship between serum high density lipoprotein and negative syndrome in antipsychotic-naive schizophrenia | |
dc.type | article | |
dc.identifier.urn | urn:nbn:de:kobv:11-100144920 | |
dc.identifier.doi | http://dx.doi.org/10.18452/11527 | |
local.edoc.type-name | Zeitschriftenartikel | |
local.edoc.container-type | periodical | |
local.edoc.container-type-name | Zeitschrift | |
local.edoc.container-year | 2010 | |
dc.description.version | Peer Reviewed | |
dcterms.bibliographicCitation.doi | 10.1515/CCLM.2010.004 | |
dcterms.bibliographicCitation.journaltitle | Clinical Chemistry and Laboratory Medicine | |
dcterms.bibliographicCitation.volume | 48 | |
dcterms.bibliographicCitation.issue | 1 | |
dcterms.bibliographicCitation.originalpublishername | de Gruyter | |
dcterms.bibliographicCitation.pagestart | 95 | |
dcterms.bibliographicCitation.pageend | 98 |