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2009-09-16Zeitschriftenartikel DOI: 10.18452/11527
Inverse relationship between serum high density lipoprotein and negative syndrome in antipsychotic-naive schizophrenia
dc.contributor.authorVenkatasubramanian, Ganesan
dc.contributor.authorArasappa, Rashmi
dc.contributor.authorRao, Naren P.
dc.contributor.authorBehere, Rishikesh V.
dc.contributor.authorKalmady, Sunil
dc.contributor.authorGangadhar, Bangalore N.
dc.date.accessioned2017-06-17T08:16:06Z
dc.date.available2017-06-17T08:16:06Z
dc.date.created2010-07-01
dc.date.issued2009-09-16
dc.identifier.issn1437-4331
dc.identifier.urihttp://edoc.hu-berlin.de/18452/12179
dc.description.abstractBackground: Recent literature suggests a role for apolipoprotein L (apoL) aberrations in the pathogenesis of schizophrenia. ApoL is almost exclusively associated with apolipoprotein A-I in high-density lipoproteins (HDLs). The objective of this study was to examine the correlation between symptom scores and serum HDL in antipsychotic-naive schizophrenia patients. Methods: In this cross-sectional study, 60 antipsychotic-naive schizophrenia patients were systematically examined for their symptom scores, with good inter-rater reliability. Concurrently, an overnight fasting serum lipid profile from these patients was assessed. Results: Serum HDL had a significant inverse correlation with a total negative syndrome score (ρ=−0.43; p=0.001). Conclusions: The study observation supports the potential role for HDL abnormalities in the genesis of negative symptoms in schizophrenia. Clin Chem Lab Med 2010;48:95–8.eng
dc.language.isound
dc.publisherKooperation de Gruyter
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleInverse relationship between serum high density lipoprotein and negative syndrome in antipsychotic-naive schizophrenia
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:11-100144920
dc.identifier.doihttp://dx.doi.org/10.18452/11527
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-year2010
dc.description.versionPeer Reviewed
dcterms.bibliographicCitation.doi10.1515/CCLM.2010.004
dcterms.bibliographicCitation.journaltitleClinical Chemistry and Laboratory Medicine
dcterms.bibliographicCitation.volume48
dcterms.bibliographicCitation.issue1
dcterms.bibliographicCitation.originalpublishernamede Gruyter
dcterms.bibliographicCitation.pagestart95
dcterms.bibliographicCitation.pageend98

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